Very First Human Trials Using Cannabis To Treat Brain Cancer Under Way


advertisement - learn more

cellsThe picture to your left is showing immunofluorescence of the human glioma cell line. (View more pictures here)

A European based pharmaceutical company called GW Pharmaceuticals is set to commence its first phase of clinical trials for the treatment of Glioblastoma Multiforme (GBM). It’s a bio-pharmaceutical company focused on discovering, developing and commercializing novel therapeutics from its proprietary cannabinoid product platform.

According to the New England Journal of Medicine, GBM accounts for approximately 50% of the 22,500 new cases of brain cancer diagnosed in the United States alone each year.(1) Treatment with regards to brain cancer are very limited which makes the study of cannabis and its effect on brain tumors crucial.

It’s about time, isn’t it? For several years now, pre-clinical research conducted by multiple scientists and universities all over the world have demonstrated that cannabinoids inhibit the viability of glioma cells both in vitro and in vivo. This happens through the process of apoptosis, or programmed cell death. Cannabis has successfully demonstrated tumor growth-inhibiting action and an improvement in the therapeutic efficacy of temozolomide, a standard treatment for glioma. GW pharmaceuticals have also followed this research and also conduct it themselves. As a result they’ve shown tumor response to be positively associated with tissue levels of cannabinoids.

We are very excited about moving this compound into further human study and the prospects of cannabinoids as new anti-cancer treatments. This is GW’s first clinical study of cannabinoids as a potential treatment to inhibit tumor growth. We believe this clinical program demonstrates the flexibility and broad application of GW’s cannabinoids platform to treat significant, unmet therapeutic needs. – Dr Steven Wright, Director of Research and Development at GW

The study will involve 20 patients, it will be a two-part study with an open-label phase to assess safety and tolerability of GW cannabinoids in combination with temozolomide, and a double-blind, randomized, placebo-controlled phase with patients randomized to active or placebo.

The study objective is to assess the tolerability, safety, and pharmacodynamics of a mixture of two principal cannabinoids, THC and CBD in a 1:1 allocation ration, in combination with temozolomide in patients with recurrent GBM.

Unfortunately the study won’t be entirely cannabis, as mentioned earlier. It will in combination with temozolomide, an oral chemotherapy drug. Who knows what effect this may have with regards to using cannabis as treatment, but we will find out. Prior studies indicate that it (cannabis) does nothing but help.

Earlier I published an article outlining four medical studies that prove cannabis can be an effective treatment, and even cure for brain cancer. Here (below) they are again just in-case you missed it. It’s potential benefits are not limited to brain cancer, but all kinds of cancer that suggest a massive amount of human clinical trials should begin. Take a look at the top 20 medical studies that prove cannabis can cure cancer.

In my opinion, many human trials have already been conducted outside of the medical field. A large number of people have used cannabis to treat their cancer, and have been successful in doing so. It’s very hard to trust pharmaceutical companies these days. Home grown GMO and pesticide free cannabis would be ideal, and don’t forget that the best method of ingestion is eating it as opposed to smoking it.

Hopefully this article sparks you to further your research on the healing properties of this plant if you’re interested. It’s a gift from nature and should not be taken lightly when it comes to its medicinal properties. It seems nature has a cure for everything, but our medicine has become an industry. I am a big believer that everything has a cure.

 1.  A study published in the British Journal of Cancerconducted by the Department of Biochemistry and Molecular Biology at Complutense University in Madrid, this study determined that Tetrahydrocannabinol (THC) and other cannabinoids inhibit tumour growth. They were responsible for the first clinical study aimed at assessing cannabinoid antitumoral action. Cannabinoid delivery was safe and was achieved with zero psychoactive effects. THC was found to decrease tumour cells in two out of the nine patients.

2. A study published in The Journal of Neuroscience examined the biochemical events in both acute neuronal damage and in slowly progressive, neurodegenerative diseases. They conducted a magnetic resonance imaging study that looked at THC (the main active compound in marijuana) and found that it reduced neuronal injury in rats. The results of this study provide evidence that the cannabinoid system can serve to protect the brain against neurodegeneration.

3. A study published in The Journal of Pharmacology And Experimental Therapeutics already acknowledged the fact that cannabinoids have been shown to possess antitumor properties. This study examined the effect of cannabidiol (CBD, non psychoactive cannabinoid compound) on human glioma cell lines. The addition of cannabidiol led to a dramatic drop in the viability of glioma cells. Glioma is the word used to describe a brain tumour.  The study concluded that cannabidiol was able to produce a significant antitumor activity.

4. A study published in the journal Molecular Cancer Therapeutics outlines how brain tumours are highly resistant to current anticancer treatments, which makes it crucial to find new therapeutic strategies aimed at improving the poor prognosis of patients suffering from this disease. This study also demonstrated the reversal of tumour activity in Glioblastoma multiforme.

 Sources:

http://www.gwpharm.com/GW%20Pharmaceuticals%20Commences%20Phase%201b2a%20Clinical%20Trial%20%20for%20the%20Treatment%20of%20Glioblastoma%20Multiforme%20GBM.aspx

advertisement - learn more

More From 'Awareness'

CE provides a space for free thinkers to explore and discuss new, alternative information and ideas. The goal? Question everything, think differently, spread love and live a joy filled life.

  1. If I got that sick the last thing I would do is see a doctor.

  2. Pingback: Very First Human Trials Using Cannabis To Treat Brain Cancer Under Way | Collective-Evolution | auntiebs

  3. Pingback: Go Puff Daddy! Research indicates marijuana helps chronic pain AND helps clear free-radicals from the brain | thefibrocoach

  4. Pingback: Contrary To What We’re Told ALS Does Have Known Causes & Treatments – Here They Are | The Viral Times

  5. maybe I will live long enough to get a try at this?/

  6. Pingback: Contrary To What We’re Told ALS Does Have Known Causes & Treatments – Here They Are | In the Now

  7. Pingback: Contrary To What We’re Told ALS Does Have Known Causes & Treatments – Here They Are | Awareness Zone

  8. Pingback: Contrary To What We’re Told ALS Does Have Known Causes & Treatments – Here They Are | Collective-Evolution

  9. Pingback: Puff Daddy! New studies reveal marijuana helps pain, muscle spasm AND autoimmune diseases | fibeegirls.com

  10. AMINANT

    I was diagnosed with stage IV lung cancer in October 2013. In December my doctor was pressuring me to get one of my lung nodules removed and begin chemotherapy as soon as possible. I wanted to wait it out just a little bit longer, I guess my intuition was telling me something. While browsing online I stumbled upon a website:www.phoenixtears.ca and was very interested. It seemed unreal, It was very hard to believe but I bought his book and read it cover to cover. Wow, that is all I could say. The things I read flipped my understanding of nutrition and cancer upside down. And my doctor never told me any of these things.I ordered for his oil on:ricksimpsoncancercure@outlook.com and was delivered to me within 48 hours, I started the protocol the same day after finishing the book. A few days later I woke up and I had no pain in my side, that was interesting. Two days later I could walk outside for a good half an hour and not get fatigued. My health was improving so fast I actually couldn’t believe it. A week later I sent my HCG urine test in and it went down by 5 points!! I had to get these results tested with my doctor just to be sure. I scheduled an appointment, did my scans, and guess what. Two of my tumors had disappeared, and the third one was half the size, this is in three weeks after starting the protocol. One month later my doctor officially pronounced me cancer free. I owe my life to you RICK SIMPSON and I thank you dearly. I will pass this information to everyone I know and I hope all those suffering from cancer know that it’s not the end, there is a way!

    • As states legalize pot the it will be critical they get people to use it. Plenty of people will use it recreational but that’s not enough to line all the pockets planning on getting filthy rich off of legalized pot.

      There are going to be all kinds of creeps coming out of the woodwork trying to sell cannabis as a cure all and no one will stop them because the business is more important than the facts.

      Cannabis or cannabis oil does not cure any thing. The ONLY thing it can do is relax a person or help a person sleep which in turn boost immunity because peace of mind and sleep boost immunity, cannabis without peace of mind and better sleep will not boost immunity.

      Smoke pot because you are an adult and it is your right but don’t believe for one second that cannabis is a cure all or a cure anything. Those claims are not from real people, just people with a product to sell.

      FYI https://www.facebook.com/beimmunetodisease?ref=hl

      • Mike Krehl

        Dear David, Your statement “Cannabis or cannabis oil does not cure any thing. The ONLY thing it can do is relax a person or help a person sleep which in turn boost immunity” is inaccurate. Studies from around the world verify the efficacy of cannabis therapeutics in not only halting the proliferation of cancer cells (stopping cancer cells from spreading to healthy cells) but also shows that cannabis induces cancer cell apoptosis (encourages programmed cell death in cancer cells) which leads to tumors shrinking. So, while you are correct in saying that it helps a person relax, sleep and assists in boosting ones immune system, that is most certainly NOT the ONLY thing that it can do!! The information Is uot there, we just need to educate ourselves and others!!

        • Mike, studies do not verify anything, if they did there would be cures and preventions. Studies are nothing but marketing, made up solely of hypothesis. The people behind the studies you are so blindly loyal to simply BELIEVE cannabis is useful but, do they really BELIEVE it to be useful or are they just trying to build more appreciation for the cannabis industry? YOU WILL NEVER KNOW.

          Furthermore, there are no studies on the human immune system so you and the other cannabis lovers have no idea what the immune system can do or does.

          https://www.facebook.com/beimmunetodisease

          Sorry Mike, cannabis only brings a bit of peace of mind to some, some it doesn’t even do that.

          “Studies” mean absolutely nothing except marketing. That’s a fact.

        • “Studies” show there is a new disease threatening the world called Ebola but it doesn’t make it true. The “studies” are paving the way for the most profitable disease the world has ever known. It’s a very simple business plan, those who create “studies” take a COMMON group of signs and symptoms and then link them to a virus that cannot be proven to exist or proven doesn’t exist and then use propaganda to literally scare people to an actual DEATH.

          Every day in Texas people die who have the same exact signs and symptoms as the person who supposedly diet of Ebola. It is quite possible that half the American population will test positive for Ebola if they faked signs and symptoms and demanded to be tested because the test for viruses do not detect any actual virus, they detect “indications”, “indications” that do not truly indicate any presence of any particular pathogen.

          AIDS was very profitable, but will not even compare to what Ebola will generate. AIDS was marketed to be a discriminative disease only threatening homosexuals, drug users and promiscuous people. Ebola is being marketed to threaten people of all walks of life.

          I predict when the industry of medicine and commercial science, those who create your so-called “studies” hit their predicted profit margin they will miraculously come up with a vaccination, probably saline and nothing more and sell it for $60 a pop and then they will declare the disease as NO LONGER A THREAT and the fear will abate and it will be history. The question is how many people do they destroy through fear before they consider the profits to be enough. Of course population control is also important to those who are in charge of the “studies” people remain so loyal too.

          Before anyone gets too angry about my comment here, let it be known if you get a chronic headache caused by nothing more than sinus pressure and you go to the doctor and they diagnose you with Ebola, the diagnoses will kill you not some germ or virus. Fear is far more deadly than any pathogen. “Studies” only mean profit, they mean nothing more.

          https://www.facebook.com/beimmunetodisease

      • Love Is The Answer

        David Flowers: You need to bone up on your scientific homework, Bro. The *smoking* of cannabis doesn’t cure cancer, but *ingesting* its extract oil most certainly does. Via empirical evidence, the cannabinoids in cannabis have proven to induce what’s called apoptosis (cell death) in cancer tumor cells, shrinking them into oblivion. International studies – namely in Spain and Canada – have been going on for the past few decades proving that fact via empirical evidence. WE in the US don’t hear about it because Big Pharma profits a whopping $185 billion per year on cancer alone. The US government has known since 1974 that it can cure most cancers if the correct protocol is applied; they even own a patent on it. Connect the dots, for crying out loud, and wake up.

        • “Bone up on my science”, are you kidding, I could get a degree in science and medicine from Berkley, Harvard, Oxford and Yale all in one and I wouldn’t be any more equipped to offer any “study” for the betterment of humanity than a 4 year old child. The reason being, today’s science is not science, it is marketing and PURE propaganda. If I told you to write a two paragraph paper on actual “cancer” facts you couldn’t do it, you couldn’t even copy and paste two paragraphs of facts from the American Cancer Society and the reason being is there are NO FACTS. Everything consumers believe to be fact is nothing more than hypothesis in other words profitable beliefs. Whatever you attempt to suggest is fact will prove to be nothing but a best guess.

          “Bone up on my science”, I’m the leading scientific EXPERT in the world when it comes to health, healing and disease. I’m the ONLY scientist in the world who provides factual science and data because I’m the only person stubborn enough to insist on truth. But that’s not all, I provide immunity to my clients and I maintain immunity in myself, immunity to all disease because I am BONED up on REAL science. I know how the human immune system works, I know why yours does not keep you immune to cancer or other disease, but mostly I know how to help you get your immune prowess back. However if you insist on remaining loyal to commercial scientific fantasy that proves to fail every time but makes more money through failure than any industry can make through success, be my guest. There is no science in regards to health and healing today outside of my work. https://www.facebook.com/beimmunetodisease

          There is no real science in regards to cannabis oil just a bunch of brainwashed, misinformed, pompous and corrupt idiots with top degrees in science fiction. If “cancer” is ever to be prevented or cured it will only be through the human immune system and it doesn’t take much more than a week or two. They push products because they can sell them and the science you mentioned isn’t science at all, otherwise they would already be telling you about your immune system so you wouldn’t waste all your money on cannabis oil. Bone up my friend.
          As it is, you are simply trying to trade one fraud for another. As long as you keep chasing the carrot, you will never know what it is to be disease free.

  11. Pingback: » Man Pushing 80 Years Given Two Weeks To Live – Cured His Cancer Using Cannabis ~ (Article)

  12. W.White

    my 8 month old baby has a astrocytoma glioma and is currently on weekly treatments of chemotherapy (vincristine and carboplatin) for about 4 weeks now. She is now having complications due to chemo including neutropenia, GI issues. We are interested in CBD therapy but live in a state where it is not an option. I would really appreciate any helpful info or suggestions. Thank you.

  13. Pingback: Cannabis Oil Dissolves Large Inoperable Cancerous Tumor In 8 Month Old Baby | Awareness Zone

  14. Pingback: Cannabis Oil Dissolves Large Inoperable Cancerous Tumor In 8 Month Old Baby | Collective-Evolution

  15. Pingback: Medical Marijuana And All It's Uses | Stoner In The Pulpit

  16. Pingback: Miracle #1837 | The Miraculist Blog

  17. mary

    My Husband that was highly infected with cancer of the lungs, he was even given days that he would live is now as healthy as a new born baby with the help of Rick Simpson Hemp Oil.
    I acquire the Hemp oil medication from which was used in curing my Husband lungs cancer within 90 days of treatment as said by Rick Simpson. you can contact them on every medical challenges his email: ricksimpsoncancerfoundation@gmail.com for more help.
    Once again i want to appreciate them and their wonderful Hemp Oil which saved my family. We are now happy family with my Husband back alive ,strong and healthy. you can contact them on every medical challenges his email: ricksimpsoncancerfoundation@gmail.com for more help.

  18. Pingback: Cannabis to treat brain cancer | CANCER

  19. Pingback: Man Pushing 80 Years Given Two Weeks To Live – Cured His Cancer Using Cannabis |

  20. Pingback: Man Pushing 80 Years Given Two Weeks To Live – Cured His Cancer Using Cannabis | Wausau News

  21. Pingback: Man Pushing 80 Years Given Two Weeks To Live – Cured His Cancer Using Cannabis

  22. Pingback: Video: Man Pushing 80 Years Given Two Weeks To Live Cured His Cancer Using Cannabis | Kannaway Global

  23. Pingback: Man Pushing 80 Years Given Two Weeks To Live – Cured His Cancer Using Cannabis | CBD Health and Beauty...Launching March 1

  24. Pingback: Man Pushing 80 Years Given Two Weeks To Live – Cured His Cancer Using Cannabis | Collective-Evolution

  25. My wife & I lost our 30 year old daughter to a childhood brain tumor which the doctors went in to debulk and they got a mere fraction of it and what was a benign tumor began to behave aggressively… As a result of the cock-ups, she ended up with VP SHUNTS which were not managed properly and when they did attend to them it was too late… All the while, feeding her on CANNABIS OIL during the course of her illness meant that the tumor did not affect her in anyway – neither headaches, seizures or anything!!! She travelled for 10 hours during one of the toughest times in her journey from Vancouver Int’l Airport to London Heathrow after ingesting about a gram & half of oil before her flight and did not sleep a wink for 10 hours.The problem was her SHUNTS which eventually took her out!!! So for all the JACKASSES* who want to place their “FAITH” in medical science (especially DOCTORS) – good luck to ‘em!!! I believe my healthcare is my business and the rite to self-medicate is PERSONAL & SACROSANCT!!!

Leave a Reply

Featured TEDx Talk

TEDx - Agents of Change
Connect, Inspire, Chat & Share!
advertisement - learn more
CE Radio - Listen now!
Amazers
Subscribe to CE Magazine Monthly For Exclusive Content!
The Mind Unleashed
advertisement - learn more

We Recommend

www.truththeory.com

Trending Now

fast

14 Fast Food & Restaurant Employees Confess The One Item You Should Never Order

People all over the world are starting to be more conscious about the food that they eat. Fast food restaurants are full of food that is literally designed to turn people into addicts. They are often littered with and chemically…