Very First Human Trials Using Cannabis To Treat Brain Cancer Under Way

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cellsThe picture to your left is showing immunofluorescence of the human glioma cell line. (View more pictures here)

A European based pharmaceutical company called GW Pharmaceuticals is set to commence its first phase of clinical trials for the treatment of Glioblastoma Multiforme (GBM). It’s a bio-pharmaceutical company focused on discovering, developing and commercializing novel therapeutics from its proprietary cannabinoid product platform.

According to the New England Journal of Medicine, GBM accounts for approximately 50% of the 22,500 new cases of brain cancer diagnosed in the United States alone each year.(1) Treatment with regards to brain cancer are very limited which makes the study of cannabis and its effect on brain tumors crucial.

It’s about time, isn’t it? For several years now, pre-clinical research conducted by multiple scientists and universities all over the world have demonstrated that cannabinoids inhibit the viability of glioma cells both in vitro and in vivo. This happens through the process of apoptosis, or programmed cell death. Cannabis has successfully demonstrated tumor growth-inhibiting action and an improvement in the therapeutic efficacy of temozolomide, a standard treatment for glioma. GW pharmaceuticals have also followed this research and also conduct it themselves. As a result they’ve shown tumor response to be positively associated with tissue levels of cannabinoids.

We are very excited about moving this compound into further human study and the prospects of cannabinoids as new anti-cancer treatments. This is GW’s first clinical study of cannabinoids as a potential treatment to inhibit tumor growth. We believe this clinical program demonstrates the flexibility and broad application of GW’s cannabinoids platform to treat significant, unmet therapeutic needs. – Dr Steven Wright, Director of Research and Development at GW

The study will involve 20 patients, it will be a two-part study with an open-label phase to assess safety and tolerability of GW cannabinoids in combination with temozolomide, and a double-blind, randomized, placebo-controlled phase with patients randomized to active or placebo.

The study objective is to assess the tolerability, safety, and pharmacodynamics of a mixture of two principal cannabinoids, THC and CBD in a 1:1 allocation ration, in combination with temozolomide in patients with recurrent GBM.

Unfortunately the study won’t be entirely cannabis, as mentioned earlier. It will in combination with temozolomide, an oral chemotherapy drug. Who knows what effect this may have with regards to using cannabis as treatment, but we will find out. Prior studies indicate that it (cannabis) does nothing but help.

Earlier I published an article outlining four medical studies that prove cannabis can be an effective treatment, and even cure for brain cancer. Here (below) they are again just in-case you missed it. It’s potential benefits are not limited to brain cancer, but all kinds of cancer that suggest a massive amount of human clinical trials should begin. Take a look at the top 20 medical studies that prove cannabis can cure cancer.

In my opinion, many human trials have already been conducted outside of the medical field. A large number of people have used cannabis to treat their cancer, and have been successful in doing so. It’s very hard to trust pharmaceutical companies these days. Home grown GMO and pesticide free cannabis would be ideal, and don’t forget that the best method of ingestion is eating it as opposed to smoking it.

Hopefully this article sparks you to further your research on the healing properties of this plant if you’re interested. It’s a gift from nature and should not be taken lightly when it comes to its medicinal properties. It seems nature has a cure for everything, but our medicine has become an industry. I am a big believer that everything has a cure.

 1.  A study published in the British Journal of Cancerconducted by the Department of Biochemistry and Molecular Biology at Complutense University in Madrid, this study determined that Tetrahydrocannabinol (THC) and other cannabinoids inhibit tumour growth. They were responsible for the first clinical study aimed at assessing cannabinoid antitumoral action. Cannabinoid delivery was safe and was achieved with zero psychoactive effects. THC was found to decrease tumour cells in two out of the nine patients.

2. A study published in The Journal of Neuroscience examined the biochemical events in both acute neuronal damage and in slowly progressive, neurodegenerative diseases. They conducted a magnetic resonance imaging study that looked at THC (the main active compound in marijuana) and found that it reduced neuronal injury in rats. The results of this study provide evidence that the cannabinoid system can serve to protect the brain against neurodegeneration.

3. A study published in The Journal of Pharmacology And Experimental Therapeutics already acknowledged the fact that cannabinoids have been shown to possess antitumor properties. This study examined the effect of cannabidiol (CBD, non psychoactive cannabinoid compound) on human glioma cell lines. The addition of cannabidiol led to a dramatic drop in the viability of glioma cells. Glioma is the word used to describe a brain tumour.  The study concluded that cannabidiol was able to produce a significant antitumor activity.

4. A study published in the journal Molecular Cancer Therapeutics outlines how brain tumours are highly resistant to current anticancer treatments, which makes it crucial to find new therapeutic strategies aimed at improving the poor prognosis of patients suffering from this disease. This study also demonstrated the reversal of tumour activity in Glioblastoma multiforme.


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  3. maybe I will live long enough to get a try at this?/

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    I was diagnosed with stage IV lung cancer in October 2013. In December my doctor was pressuring me to get one of my lung nodules removed and begin chemotherapy as soon as possible. I wanted to wait it out just a little bit longer, I guess my intuition was telling me something. While browsing online I stumbled upon a and was very interested. It seemed unreal, It was very hard to believe but I bought his book and read it cover to cover. Wow, that is all I could say. The things I read flipped my understanding of nutrition and cancer upside down. And my doctor never told me any of these things.I ordered for his oil and was delivered to me within 48 hours, I started the protocol the same day after finishing the book. A few days later I woke up and I had no pain in my side, that was interesting. Two days later I could walk outside for a good half an hour and not get fatigued. My health was improving so fast I actually couldn’t believe it. A week later I sent my HCG urine test in and it went down by 5 points!! I had to get these results tested with my doctor just to be sure. I scheduled an appointment, did my scans, and guess what. Two of my tumors had disappeared, and the third one was half the size, this is in three weeks after starting the protocol. One month later my doctor officially pronounced me cancer free. I owe my life to you RICK SIMPSON and I thank you dearly. I will pass this information to everyone I know and I hope all those suffering from cancer know that it’s not the end, there is a way!

    • As states legalize pot the it will be critical they get people to use it. Plenty of people will use it recreational but that’s not enough to line all the pockets planning on getting filthy rich off of legalized pot.

      There are going to be all kinds of creeps coming out of the woodwork trying to sell cannabis as a cure all and no one will stop them because the business is more important than the facts.

      Cannabis or cannabis oil does not cure any thing. The ONLY thing it can do is relax a person or help a person sleep which in turn boost immunity because peace of mind and sleep boost immunity, cannabis without peace of mind and better sleep will not boost immunity.

      Smoke pot because you are an adult and it is your right but don’t believe for one second that cannabis is a cure all or a cure anything. Those claims are not from real people, just people with a product to sell.


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  10. W.White

    my 8 month old baby has a astrocytoma glioma and is currently on weekly treatments of chemotherapy (vincristine and carboplatin) for about 4 weeks now. She is now having complications due to chemo including neutropenia, GI issues. We are interested in CBD therapy but live in a state where it is not an option. I would really appreciate any helpful info or suggestions. Thank you.

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  15. mary

    My Husband that was highly infected with cancer of the lungs, he was even given days that he would live is now as healthy as a new born baby with the help of Rick Simpson Hemp Oil.
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  23. My wife & I lost our 30 year old daughter to a childhood brain tumor which the doctors went in to debulk and they got a mere fraction of it and what was a benign tumor began to behave aggressively… As a result of the cock-ups, she ended up with VP SHUNTS which were not managed properly and when they did attend to them it was too late… All the while, feeding her on CANNABIS OIL during the course of her illness meant that the tumor did not affect her in anyway – neither headaches, seizures or anything!!! She travelled for 10 hours during one of the toughest times in her journey from Vancouver Int’l Airport to London Heathrow after ingesting about a gram & half of oil before her flight and did not sleep a wink for 10 hours.The problem was her SHUNTS which eventually took her out!!! So for all the JACKASSES* who want to place their “FAITH” in medical science (especially DOCTORS) – good luck to ‘em!!! I believe my healthcare is my business and the rite to self-medicate is PERSONAL & SACROSANCT!!!

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