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Gulf War Illness Tied to Cipro Antibiotics

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gulfwarA U.S. military publication, The Air Force Times, made the connection that victims of Fluoroquinolone Toxicity Syndrome (“Floxies”) have been screaming about for years – that Gulf War Illness is tied to Cipro.  In an article entitled, “New FDA warnings on Cipro may tie into Gulf War Illness,” it was noted that the August, 2013 update to the warning labels of all fluoroquinolone antibiotics stating that PERMANENT peripheral neuropathy is a possible adverse effect, prompted The Air Force Times to make the connection.

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Civilians suffering from Fluoroquinolone Toxicity Syndrome (an adverse reaction to a fluoroquinolone – Cipro/Ciprofloxacin, Levaquin/Levofloxacin, Avelox/Moxifloxacin, Floxin/Ofloxacin and others) have noted the similarities between Gulf War illness and Fluoroquinolone Toxicity Syndrome for years.  It is beyond likely, it is probable, that they are one in the same.

The Symptoms

The VA defines Gulf War Illness as “chronic, unexplained symptoms existing for 6 months or more” that are at least ten percent disabling.  The CDC case definition of Gulf War Illness “requires chronic symptoms in two of three domains of fatigue, cognitive-mood, and musculoskeletal.”

Fluoroquinolone Toxicity Syndrome is a chronic, unexplained illness with symptoms lasting for months, years, or, as the updated warning label notes, permanently.  The symptoms of Fluoroquinolone Toxicity Syndrome are too numerous to list, but a cursory glance at the warning label for Cipro/Ciprofloxacin will tell you that the effects include musculoskeletal problems and central nervous system issues.  Additionally, as  pharmaceuticals that damage mitochondria, the energy centers of cells, severe fatigue is often induced by Fluoroquinolones.

A 1998 study entitled, “Chronic Multisymptom Illness Affecting Air Force Veterans of the Gulf War,” found that the most commonly reported symptoms of Gulf War Illness are sinus congestion, headache, fatigue, joint pain, difficulty remembering or concentrating, joint stiffness, difficulty sleeping, abdominal pain, trouble finding words, (feeling) moody or irritable, rash or sores, numbness or tingling and muscle pain.

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A 2011 study conducted by the Quinolone Vigilance Foundation found that the most commonly reported symptoms of Fluoroquinolone Toxicity Syndrome are tendon, joint, and muscle pain, fatigue, popping/cracking joints, weakness, neuropathic pain, paresthesia (tingling), muscle twitching, depression, anxiety, insomnia, back pain, memory loss, tinnitus, muscle wasting.

The symptoms are similar enough to raise a few eyebrows.  It should be noted that when a chronic, multi-symptom illness suddenly sickens a patient or a soldier, and he or she goes from being healthy and active to suddenly being exhausted and unable to move or think, it is difficult to pinpoint and describe exactly what is going wrong in his or her body.  Thus, even if the symptoms are identical, they may not be described in an identical way because of context and differing areas of focus.

For victims of fluoroquinolones, it is as if a bomb went off in the body of the victim, yet all tests come back “normal” so in addition to physical pain and suffering that the soldier/patient is going through, he or she has to suffer through dismissal and denial from medical professionals as well.  Neither Gulf War Illness nor Fluoroquinolone Toxicity Syndrome are detected by traditional medical tests and thus both diseases are systematically denied.  All blood and urine markers come back within the normal ranges, yet the patient or soldier is suddenly incapable of 90% of what he or she used to be able to do.  When a large number of patients or soldiers (nearly 30% of the soldiers serving in the Gulf reported symptoms.  Exact numbers of civilian patients suffering from Fluoroquinolone Toxicity Syndrome are unknown because of delayed reactions, misdiagnosing the illness, tolerance thresholds, etc.) experience adverse reactions that are undetectable using the tests available, there is something wrong with the tests.  The patients and soldiers aren’t lying and their loss of abilities isn’t “in their heads.”

Exposure to the same Poison

Another glaring similarity between Gulf War Illness and Fluoroquinolone Toxicity Syndrome is that everyone with either syndrome took a Fluoroquinolone.

Per a Veteran of the Marines who commented on healthboards.com about the use of Ciprofloxacin by soldiers in the Gulf:

“The Ciprofloxacin 500 mg were ordered to be taken twice a day. The Marines were the only service that I know for sure were given these orders. We were ordered to start them before the air war, and the order to stop taking them was giver at 0645 Feb 28th 1991 by General Myatt 1st Marine div commander. We were forced to take Cipro 500mg twice a day for 40 plus days. so the Marines were given NAPP (nerve agent protection pills) or pyridiostigmine bromide to protect us from nerve agent, and We were ordered to take the Cipro to protect from anthrax. We were part of the human research trial conducted by the Bayer corporation in the creation of their new anthrax pills. At that time they had no idea of the side effects of flouroquinolones. That’s the class of medications that Cipro falls into. After the Gulf War the FDA and Bayer co. started releasing the list of side effects.  You do need to know what was done to you so you will have to do your own research. Good luck to all of you and Semper Fi.”

By definition, everyone who suffers from Fluoroquinolone Toxicity Syndrome has taken a fluoroquinolone – Cipro/Ciprofloxacin, Levaquin/Levofloxacin, Avelox/Moxifloxacin or Floxin/Ofloxacin.  Civilians are also part of the “human research trial conducted by the Bayer corporation” as well as Johnson & Johnson, Merck and multiple generic drug manufacturers who peddle fluoroquinolones as “safe” antibiotics.

The Case Against Fluoroquinolones

Of course, there were multiple chemicals and poisons that Gulf War Veterans were exposed to in the 1990-91 Persian Gulf War and thus it has been difficult to pinpoint an exact cause of Gulf War Illness.  The ruling out of the following possible causes should certainly be questioned thoroughly, but “depleted uranium, anthrax vaccine, fuels, solvents, sand and particulates, infectious diseases, and chemical agent resistant coating” have been found not to cause Gulf War Illness.  Other potential causes of Gulf War Illness include oil fires, multiple vaccines, pesticides, and, of course, fluoroquinolone antibiotics (Cipro).  (It should be noted that non-deployed military personnel who served during the Gulf War period, but who were not deployed in the Middle East, have also been afflicted with Gulf War Illness and thus toxins that both deployed and non-deployed personnel have been exposed to should be the focus of investigations into the causes of Gulf War Illness.)

The Air Force Times article is one of the first official mentions of the relationship between Cipro and Gulf War Illness.  Officially, the link hasn’t been examined (though some very smart researchers are building a case as you read this).  Why Cipro hasn’t been looked at as a potential cause of Gulf War Illness is a question that I don’t know the answer to.  Perhaps it’s because most people think that all antibiotics are as safe as penicillin.  Perhaps it’s because most people have a tolerance threshold for fluoroquinolones and don’t react negatively to the first prescription that they receive.  Perhaps it’s because even today, more than 30 years after Cipro was patented by Bayer, the exact mechanism by which fluoroquinolones operate is still officially unknown (1).  Perhaps it’s because it is unthinkable that a commonly used antibiotic could cause a chronic syndrome of pain and suffering.  Perhaps it’s because the tests that show the damage done by fluoroquinolones aren’t used by the VA or civilian doctors’ offices.  Perhaps it’s because fluoroquinolones are the perfect drug – they take an acute problem – an infection, and convert it into a chronic disease-state that is systematically misdiagnosed as fibromyalgia, chronic fatigue syndrome, an autoimmune disease, leaky gut syndrome, insomnia, anxiety, depression, etc. and turns formerly healthy people into lifetime customers of the medical establishment / pharmaceutical companies.  Perhaps it is simply widespread ignorance about the way these dangerous drugs work.

The Cliffs Notes version of how fluoroquinolones work is as follows:

The fluoroquinolone depletes liver enzymes that metabolize drugs (CYP450) (2).  When the enzymes are depleted sufficiently, the fluoroquinolone forms a poisonous adduct to mitochondrial DNA (mtDNA) (3, 4), which destroys and depletes mtDNA (5).  While the mtDNA is being destroyed, the fluoroquinolone is also binding to cellular magnesium. (6, 7)  The mitochondria reacts to being assaulted by producing reactive oxygen species (ROS) (8, 9).  Some of the ROS, specifically hydrogen peroxide, combines with the excess calcium (there is a balance in cells of magnesium and calcium and the binding of the magnesium results in an excess of calcium) to induce the expression of CD95L/Fas Ligand (5) which then causes cell death (apoptosis) and immune system dysfunction (10) which leads the body to attack itself – like an autoimmune disease.

Damage is caused by every single step in the process.  Additional damage may be done by the fluorine atom that is added to fluoroquinolones to make them more potent.  It should be noted that the complexity of these cellular interactions is too vast to write up in this article.

Every symptom of Gulf War Illness is consistent with mitochondrial damage and oxidative stress (11), both of which have been shown to be brought on by fluoroquinolones.

Though the tests used in typical medical practice show no reason for victims of fluoroquinolones to be ill, that fact simply shows that the wrong tests are being used.  Tests of mitochondrial function, antioxidant/oxidant ratios and DNA will show the damage that is done by fluoroquinolones.  The way to determine whether Cipro is the cause of Gulf War Illness is to conduct a DNA mass spectrogram analysis on afflicted Gulf War Veterans.  If the DNA mass spectrogram analysis shows that quinolone molecules have adducted to the DNA of the Veterans, that’s a smoking gun of damage done by Cipro.

Millions of civilians have also been hurt by fluoroquinolones.  I can connect fluoroquinolones to almost every chronic disease that has increased in prevalence since the introduction of fluoroquinolones to the mass population in the mid-1980s.  Additionally, DNA is damaged and thus the effects are intergenerational and many of the chronic diseases that plague children can be linked to fluoroquinolone use by parents.

Some very well-respected researchers are working on more furthering  the case that Cipro is responsible for Gulf War Illness.  If any Gulf War Veterans want to take on Bayer before those studies are released, the way to do so is through obtaining a DNA mass spectrogram analysis and having it analyzed by a toxicologist.  It is proof of damage and it is necessary.  When that proof is obtained, I encourage all Gulf War Veterans to use it to fight those who poisoned them – Bayer and their corroborators in the DOD and the FDA.

To any Gulf War Veterans who read this – you are soldiers and you are warriors.  I know that you have been weakened, but you are still alive and those of you who can fight, should, because a grave injustice has been done to you.  It is an injustice that is also being inflicted on innocent civilians.  There is nothing okay about the poisoning of our military men and women, or the American public, with chemotherapy drugs masquerading as antibiotics.  I encourage you to fight Bayer and their corroborators like what they are – domestic terrorists.  It is a fight that you can win.  The truth, and a significant amount evidence, are on your side.

Post Script:  The author’s web site, with more information about fluoroquinolones, is www.floxiehope.com.  Further information about fluoroquinolones can be found through the Quinolone Vigilance Foundation – www.saferpills.org.

Numbered Sources:

  1. Inorganic Chemistry, “New uses for old drugs: attempts to convert quinolone antibacterials into potential anticancer agents containing ruthenium.
  2. FDA Warning Label for Ciprofloxacin
  3. The Journal of Biological Chemistry, “The Mechanism of Inhibition of Topoisomerase IV by Quinolone Antibacterials.”
  4. Findings of Toxicologist Joe King
  5. The Journal of Immunology, “Mitochondrial Reactive Oxygen Species Control T Cell Activation by Regulating IL-2 and IL-4 Expression: MechanismN of Ciprofloxacin Mediated Immunosuppression
  6. Antimicrobial Agents and Chemotherapy, “Effects of Magnesium Complexation by Fluoroquinolones on their Antibacterial Properties
  7. Proceedings of the National Academy of Sciences of the United States, Biochemistry, “Quinolone Binding to DNA Mediated by Magnesium Ions”
  8. Science Translational Medicine, “Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells
  9. Journal of Young Pharmacists, “Oxidative Stress Induced by Fluoroquinolones on Treatment for Complicated Urinary Tract Infections in Indian Patients
  10. Antimicrobial Agents and Chemotherapy, “Ciprofloxacin Induces an Immunomodulatory Stress Response in Human T Lymphocytes
  11. Nature Precedings, “Oxidative Stress and Mitochondrial Injury in Chronic Multisymptom Conditions:  From Gulf War Illness to Autism Spectrum Disorder

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Johnson & Johnson Found To Have Knowingly Allowed Asbestos In Their Baby Powder

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In Brief

  • The Facts:

    Johnson and Johnson have recently lost lawsuits for negligence in knowingly allowing carcinogenic substances in their talc-based hygiene products.

  • Reflect On:

    Are we starting to turn the page on an era where human health and safety are not the prime considerations in the manufacturing of consumer products?

We are starting to awaken to the fact that it seems to be the rule, and not the exception, that large Western corporations put profits above human health considerations. The only time they seem to give any regard to human health concerns is when their forecasts of potential lawsuits down the road would likely exceed the cost measures needed to ensure the safety of their product.

Johnson & Johnson is just one of a long line of corporate perpetrators who believed that covering up and lying about known health concerns would make better business sense than taking the time and resources to actually address those health concerns within their products.

Contaminated Baby Powder: The Height Of Indignity

One would think, regardless of an understanding that the bottom line is a priority for most private companies, that the health and safety of a nursing mother and her newborn child would be sacrosanct for any industry. The reality is that this is simply not the case, even though J&J could have mitigated this problem from the start.

Companies that mine talc are required to take extra steps to ensure the absence of asbestos in their talc. Instead, J&J allegedly went to great lengths to fake it.

Not only did the company know about the asbestos contamination, evidence suggests, but J&J also failed to warn its customers about the link between Baby Powder and cancer or replace its talc with a safer alternative. As a result, J&J guaranteed its customers’ exposure to asbestos.

And regardless of their size or numbers, asbestos fibers are lethal at any capacity. As the World Health Organization (WHO) has stressed repeatedly, there is no safe level of exposure. (source)

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The Testimony of Scientist James Webber

Baby Powder’s contamination with asbestos (a mineral that naturally occurs near talc) has long been the subject of lawsuits. But only in recent years has evidence begun to unravel J&J’s defense – that the company had no idea – and threatened its success in lawsuits to come.

In March, a California jury awarded $29 million to Terry Leavitt, a woman who said that asbestos in Johnson & Johnson’s talcum-powder-based products caused her terminal mesothelioma. Environmental scientist James Webber testified in her high-profile California trial and made these observations:

During several hours on the stand, Webber explained how he ran tests that showed “clear” evidence of asbestos contamination in the mines from which J&J sourced talc.

“The testing I have seen [shows] that it was present at least as early as 1971 and up through the late 1990s,” said Webber, who ran an asbestos laboratory in New York state.

Despite denying it publicly, J&J had observed this contamination in internal memos. Its notes dismissed the amount of asbestos in its talc as “but a trace,” Webber alleged. But that was just an optimistic interpretation of superficial testing, he said: the tests used methods too weak to detect microscopic asbestos fibers. Webber insisted the actual tests results revealed there could be millions of asbestos fibers per gram of talc.

And J&J’s inaccurate reports were allegedly only the tip of the iceberg. In some instances, Webber said, photos attached to J&J’s reports revealed that “they had been seeing it and not reporting it.”  (source)

And It’s Getting Worse

The $29 million verdict, in California Superior Court in Oakland, was the latest defeat for the healthcare conglomerate facing more than 13,000 talc-related lawsuits nationwide. And things may be getting even worse for J&J, according to ZeroHedge:

Johnson & Johnson shares are down over 5% after Bloomberg reports that, according to people with knowledge of the matter, the U.S. Justice Department is pursuing a criminal investigation into whether Johnson & Johnson lied to the public about the possible cancer risks of its talcum powder…

Now, a grand jury in Washington is examining documents related to what company officials knew about any carcinogens in their products, the people said.

The Takeaway

It seems as though corporations have long been willing to take the calculated risk of short-cuts and denials instead of ensuring that their products are safe for public use. My suspicion is that a part of our collective awakening process will be issuing in a new business paradigm in which human health and safety become paramount.

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Awareness

Prescription Infant Formulas Found To Be Contaminated With Aluminum

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In Brief

  • The Facts:

    Multiple brands of prescription infant formula were found to contain high levels of aluminum.

  • Reflect On:

    Should we be questioning the quality of products that come from pharmaceutical production? Do we veer away from natural methods of raising children more than we should? At what cost?

You may not think aluminum is a big deal, but it is. For anybody who has looked into aluminum toxicology, it’s quite clear and apparent that it has no place inside of any living biological organism. Putting it simply, it wreaks havoc on our biology. High amounts of aluminum have been found in the brains of people with Alzheimer’s disease, with experts in the field believing that aluminum brain accumulation may be one of the main causes of Alzheimer’s disease.

It’s also been discovered within the brains of MS patients, and some of the highest aluminum content ever recorded in brain tissue has also been discovered in people with autism. Aluminum is associated with several diseases. But an adult body can do a great job of flushing out aluminum.

Despite the fact that aluminum has no place within earth’s biota, it’s still present in many of our medications, our food, and even in the water that we drink due to contamination since the industrial revolution. Aluminum inside the body is a new phenomenon and still understudied. Again, there is a threshold, and aluminum that is injected via vaccines doesn’t exit the body–there is strong evidence that it remains inside the body and ends up in distant organs and eventually inside of the brain. If you want to access more studies on that topic, you can read this article I published that provides them and goes into more detail. You can also watch this interview with Christopher Exley, where he also points to that fact.

A new study published in the International Journal of Environmental Research and Public Health has shown that multiple popular infant prescriptions are contaminated with aluminum. You may be asking how much aluminum, but the authors make it a point to stress that there are no safe amounts of aluminum levels that can be inside of a human body, let alone a newborn baby. That being said, the amounts found are listed within the abstract of the study:

Historical and recent data demonstrate that off-the-shelf infant formulas are heavily contaminated with aluminium. The origin of this contamination remains to be elucidated though may be imported via ingredients, packaging and processing. Specialised infant formulas exist to address health issues, such as low birth weight, allergy or intolerance and medical conditions, such as renal insufficiency. The aluminium content of these prescription infant formulas is measured here for the first time. We obtained 24 prescription infant formulas through a paediatric clinic and measured their total aluminium content by transversely heated graphite furnace atomic absorption spectrometry following microwave assisted acid/peroxide digestion. The aluminium content of ready-to-drink formulas ranged from 49.9 (33.7) to 1956.3 (111.0) μg/L. The most heavily contaminated products were those designed as nutritional supplements for infants struggling to gain weight. The aluminium content of powdered formulas ranged from 0.27 (0.04) to 3.27 (0.19) μg/g. The most heavily contaminated products tended to be those addressing allergies and intolerance. Prescription infant formulas are contaminated with aluminium.

Another very important point made right off the bat by the authors:

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Human exposure to aluminium is a serious health concern. Aluminium exposure in infants is understandably a burgeoning issue. While infant exposure to aluminium continues to be documented, its consequences, immediate and in the future, have received only scant attention and research is required to understand the biological availability of aluminium through formula feeding. For example, how much aluminium is absorbed across the neonate gut and its subsequent fate, including excretion.

There is already too much aluminium in infant formulas and herein we have measured its content in a large number of prescription formulas, products which are fed to vulnerable infants in their first months of life. Many of these products are heavily contaminated with aluminium.

As for the specific infant formulas, you can refer to the study. The researchers obtained 24 prescription infant formulas via the Paediatric Clinic of Russells Hall Hospital in Dudley, United Kingdom. The ready-to-drink and powdered products were new, ready-to-be used and unopened samples. These formulas are for babies with some sort of growth restriction, like for preterm infants or infants who have poor weight gain. There were also powdered formulas for allergies and intolerances and powdered formulas with additional amino acids.

The authors contacted each manufacturer and expressed that they denied knowing that there was any aluminum in their products, which means it’s still a mystery as to their source. The authors hypothesize on a number of ways that aluminum could be entering into the formulas.

In their conclusion, the authors emphasize that:

Where possible, breast milk feeding should be prioritised, as the aluminium content of breast milk is invariably an order of magnitude lower than in formula feeds. Where infant formulas are the only source of nutrition for many infants in their first weeks and months of life, aluminium ingested in formula feeds will be the major contributor to their body burden of aluminium. The last thing that vulnerable infants fed specialised formulas for their specific nutritional/medicinal need is additional aluminium in their diet.

Detoxing

There is a lot of information out there on how a person can detox from aluminum and other heavy metals. There are multiple studies, and based on what I’ve looked into, water with high amounts of Silica are effective in draining aluminum out of your body and brain. Herbs like cilantro and substances like chlorella and spirulina are also great for removing some metals. The information is out there, so be sure to do your research.

The Takeaway

It’s concerning to think about what these corporations are doing. Again, aluminum should hold no place in our society, it should’ve remained well below our surface as part of the Earth’s crust for a reason. It wasn’t until humans began digging it out and using it for a number of things, irresponsibly I might add, that we started to see the health implications which still go largely ignored by the medical community.

In fact, heavy metal accumulation and detoxification of aluminum haven’t been addressed at all, which is odd given the fact that heavy metal accumulation is linked to a variety of diseases.

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Awareness

9 Studies You Should Be Aware of Before Trying The Ketogenic Diet

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In Brief

  • The Facts:

    The Ketogenic diet is a popular fad diet that promotes quick weight loss and symptom management for bodies that are dealing with poor lymph, kidney and digestion health.

  • Reflect On:

    Based on the studies that are emerging, is our desire for quick weight loss more important than living a long and healthy life? Are we learning about these diets primarily through those with strong ties to upholding these diets?

The ketogenic diet has popped up as a popular approach to weight loss in the last few years. Is it successful at that? Sure, it is. I’ve experimented with the diet myself years ago when I was looking to lose some belly fat. I was entering into ketosis in a different way than most, as I was not eating any animal products, but it does in fact work.

But like any animal product based diet, what are the consequences of eating so much food that does not truly jive with our human bodies? Not only that, is fast weight loss more important than keeping our morality rate down?

In the last few years, we’ve reported a lot on the Keto diet and the various ways it can be done. We have explored the studies, the results and in some ways, we supported it. But lately, I have been thinking about how supporting this could actually be encouraging people to jump into these diets, including the paleo diet, when in reality these diets increase mortality rates and are not healthy for the human body.

It became a thought in the back of my mind, I have always strived to put the best information out that I can through this platform to promote good health. And so we must look at that, even if that means upsetting some people who currently are on paleo or keto and are seeing some good weight loss or symptom management. The truth is, like the many people I’ve seen crash on these diets after a few years, I want people to know the truth of what’s going on out there. And how we can get beyond diets that symptom manage, and instead get onto diets that truly heal.

Anytime we have fad diets, which paleo and keto are, we see products and bias pop up all over the place to support the continuation of these trends. It becomes less about health and more about upholding an identity or a business.

So as I recently looked into what experts are saying about these diets, I came upon two important videos I think everyone should check out. Both have been embedded below. Remember, it’s not that I care what you choose in your own life, or that I feel there is a right or wrong, it’s that I believe we should be informed and I wish to use this platform to promote as best a message as I can.

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The Videos

Thanks to Plant-Based News for creating such a good channel and resource of information on YouTube.

In this video, several plant-based health experts talk through 9 nutrition studies that would be of interest to low carb keto diet proponents. To read the 9 studies, click here.

Next up, Dr. Kim Williams (past President of the American College of Cardiology) shares his insights about the ketogenic.

Related Articles

Diabetic Shares Why He Quit ‘The Ketogenic Diet’

Doctor Explains Why She Never Recommends The ‘Ketogenic Diet’

The Biggest Misconception About The ‘Ketogenic Diet’…You Don’t Actually Have To Follow It

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