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Some Doctors Don’t Believe In This Disease Yet It Predisposes Many Diseases

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mitoThe tragic case of Justina Pelletier has been in the news quite a bit lately.  Justina Pelletier is the teen (14 when her ordeal started, 15 now) who is at the center of a nasty custody battle between her parents and Boston Children’s Hospital. Boston Children’s Hospital and the Massachusetts Department of Children and Families have taken custody of Justina, against the will of her parents, because they assert that Justina’s health problems are psychosomatic and that Justina’s parents are guilty of medical abuse. Justina’s parents, on the other hand, assert that Boston Children’s Hospital has kidnapped their daughter and that Justina is in need of medical care for her mitochondrial disorder.

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Hundreds of news stories and blog posts have been written about Justina’s case.  One of the best articles that I’ve read about the horrible, tragic situation that Justina is caught in the middle of is “A Medical Collision with a Child in the Middle” in The Boston Globe.  The Boston Globe article, and many others, have given a good overview of Justina’s situation, but they have given very little information about the condition which Justina’s parents say she has and the Boston Children’s Hospital doctors deny exists – mitochondrial disease.

This post is to give some basic, introductory information about mitochondrial disease – a topic that most journalists and bloggers who have been writing about the case have glossed over, and a topic that some of the doctors in Justine’s case are woefully ignorant of.  (A doctor who Justine Pelletier sought help from “didn’t believe” in mitochondrial diseases)

Mitochondria 101

Mitochondria are the energy centers of the cells.  They are found in almost every cell in the human body and they produce more than 90% of cellular energy through the generation of ATP (Adenosine Triphosphate).  Mitochondria also play key roles in cellular processes including “calcium, copper and iron homeostatis; heme and iron-sulfer cluster assembly; synthesis of pyrimidines and steroids; thermogenesis and fever response; and calcium signaling” (1) and additionally produce ROS (reactive oxygen species) (2), which play key roles in regulating and determining apoptosis (programmed cell death), as well as signaling communication between cells and tissues.  (3)   Mitochondria have their own DNA, mtDNA, which is separate from the nuclear DNA of the cell.  Proper function of mitochondria is vital for all areas of health.

A hallmark of mitochondrial dysfunction is crippling fatigue and exhaustion.  Because mitochondria are the energy centers of cells, when they are not operating properly patients are unable to do things that require energy.  It is an organic, physical lack of energy, not a choice not to get out of bed or run around the block.

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Mito Action lists poor growth, loss of muscle coordination, muscle weakness, neurological problems, seizures, autism, visual and/or hearing problems, developmental delays, learning disabilities, heart disease, liver disease, kidney disease, GI disorders, diabetes, increased risk of infection, thyroid dysfunction, adrenal dysfunction, autonomic dysfunction and neuropsychological changes as symptoms of mitochondrial diseases.

When mitochondria are not functioning properly, multiple disease states can ensue.  According to Dr. Richard Boles, Director of the Metabolic and Mitochondrial Disorders Clinic at Children’s Hospital Los Angeles:

“these are partial defects. Mitochondrial dysfunction doesn’t really cause anything, what it does is predisposes towards seemingly everything. It’s one of many risk factors in multifactorial disease. It can predispose towards epilepsy, chronic fatigue, and even autism, but it doesn’t do it alone. It does it in combination with other factors, which is why in a family with a single mutation going through the family, everyone in the family is affected in a different way. Because it predisposes for disease throughout the entire system.” (source:  Hormones Matter)

It makes sense that when the energy centers of cells are not functioning properly, the body starts to shut down, and when the body shuts down on a cellular level, multi-symptom, diffuse illnesses result.

Mitochondrial Diseases

There are three basic categories of mitochondrial disease:  1)  Diseases that are recognized as verified mitochondrial diseases, 2)  Diseases that there is a large amount of evidence that links them to mitochondrial dysfunction, but are not generally recognized as mitochondrial diseases, and 3)  Diseases that are indirectly related to mitochondrial function.

The first category of mitochondrial diseases, those that are verified and acknowledged as mitochondrial diseases include:

  1.  Progressive External Opthalmoplegia
  2. Alper’s Syndrome
  3. Leigh’s Syndrome
  4. Friedrich’s Ataxia

These diseases are matrilineally inherited (mtDNA is passed down through the mother) and involve recognized mtDNA mutations.  The prognosis for many with these diseases is, sadly, poor, and there are “currently no pharmaceutical cures for any mitochondrial diseases.”  (3)   “Although individually rare, diseases caused by mtDNA and nDNA mutations are estimated to collectively have an incidence of ~1/4000 individuals.”  (1)  Interestingly, “a number of human mitochondrial genetic diseases that are clinically discreet are being diagnosed at unexpected rates.”  (4)  A possible explanation for an unexpected increase in hereditary mitochondrial diseases is that some of the environmental toxicants and pharmaceuticals that damage mitochondria have been shown to deplete mtDNA (5), and that depleted mtDNA may be passed from a mother on to a child.

The second category of mitochondrial diseases are diseases that are typically categorized as “mysterious diseases” of modernity.  These diseases have increased in prevalence significantly over the past 50 years.  They are controversial and their existence is denied by many.  Patients suffering from these diseases struggle to have their health problems acknowledged as having a physical cause, and are often accused of making things up or having a somatoform disorder, “a psychiatric condition when a person experiences physical pain for which no known medical explanation can be found.”   The exact cause of these diseases is officially unknown and there are many theories as to their origins.  There is much evidence, however, that these diseases at least feature, and are possibly (probably) caused by, mitochondrial dysfunction and oxidative stress (which occurs in mitochondria as a result of mitochondrial stress, damage or injury).

  1. Chronic Fatigue Syndrome / Myalgic Encephalomyelitis (ME) (6, 7)
  2. Fibromyalgia (8, 9, 10)
  3. Gulf War Syndrome (11)
  4. Autism (12, 13, 14)
  5. Fluoroquinolone Toxicity Syndrome and adverse reactions to other mitochondria damaging prescription drugs (15, 16, 17)
  6. Irritable Bowel Syndrome (IBS) (18)

All of the sources linked to are peer-reviewed.  Yet, these diseases are still woefully under-acknowledged and people, including doctors, seem to feel that they are at liberty to “not believe” in them.

There are a couple of reasons for disbelief in these diseases.  First, tests do not currently exist which can reliably determine the existence of these diseases.  An unfortunately common attitude in medicine is, “if it doesn’t show up on the tests, it doesn’t exist.”  Second, they are diseases of modernity, so there is little history from which to gather information on them.

The link between these mysterious diseases and mitochondrial damage and oxidative stress has been ignored.  This intentional ignorance is likely caused by the notion that if it is admitted that mitochondrial damage and oxidative stress are the causes of these diseases, the question may be asked, “what causes mitochondrial damage and oxidative stress?”  The answer is one that doctors, and anyone else who believes that the current medical system causes more good than harm, doesn’t want to admit – pharmaceuticals and environmental toxins are the causes of mitochondrial damage and oxidative stress. (1, 20) Chemicals in our drugs and in our environment are causing damage to our mitochondria, which are, in turn, causing multi-symptom, chronic, mysterious illnesses that afflict millions of people.

Offending drugs that cause mitochondrial damage include bactericidal antibiotics (15), statins (17), chemotherapy drugs (1), acetaminophen (4), metformin (a diabetes drug) (19), and others.  Disease states caused by chemical harm to mitochondria are often delayed and can involve a threshold of harm to the mitochondria (4), so it is often difficult to connect the mitochondria damaging chemical to the disease state.

The third category of mitochondrial diseases are those that are indirectly related to mitochondrial function.  Per a Review entitled, “Medication-induced Mitochondrial Damage and Disease,” the following diseases are related to mitochondrial damage:

“Damage to mitochondria is now understood to play a role in the pathogenesis of a wide range of seemingly unrelated disorders such as schizophrenia, bipolar disease, dementia, Alzheimer’s disease, epilepsy, migraine headaches, strokes, neuropathic pain, Parkinson’s disease, ataxia, transient ischemic attack, cardiomyopathy, coronary artery disease, chronic fatigue syndrome, fibromyalgia, retinitis pigmentosa, diabetes, hepatitis C, and primary biliary cirrhosis.”

These diseases are often associated with old age (1) but they are afflicting younger and younger people over the past couple of decades.

The Regulatory Agencies are Failing to Protect our Mitochondria

Seeing as mitochondrial health is related to almost every chronic disease there is, it wouldn’t be too much to expect for the FDA and EPA to regularly look at the effects of drugs and environmental toxins on mitochondria when determining the safety of drugs and chemicals that humans come into contact with.  However, “mitochondrial toxicity testing is still not required by the US FDA for drug approval.”  (20)  The researchers who wrote the review entitled “Mitochondria as a Target of Environmental Toxicants” in 2013, noted that, “The existence of so many mitochondrial diseases illustrates the critical importance of maintenance of mitochondrial and mtDNA integrity for health.  It also raises an important question with implications for environment-mediated mitochondrial toxicity: Why did it take us so long to realize that many diseases are in fact mitochondrial diseases?” (1)  Good question.

Ignorance surrounding mitochondrial diseases can be explained by noting the following:

  1.  Mitochondria are a strange mix of vulnerable and resistant to assaults.  All sorts of drugs and chemicals damage mitochondria, and mtDNA is far more vulnerable to damage than nuclear DNA.  However, damage to mitochondria does not manifest itself in a disease state until a certain threshold of damage has occurred.  So, an individual can tolerate a certain amount of a mtDNA depleting drug, like Cipro/Ciprofloxacin (21), until their mtDNA is depleted sufficiently, then disease states will ensue. (4)
  2. The onset of diseases caused by mitochondrial damage are often delayed for days, months or even years after the offending chemical has done damage.  (4)
  3. Inertia.  The role of mitochondria in health has been ignored for years.  It would require a paradigm shift for medical professionals to start noticing mitochondrial dysfunction.  And if they start noticing mitochondrial dysfunction, they might start to realize that their drugs are the cause of the dysfunctional mitochondria.  (1, 20)
  4. There is very little that Western Medicine can do to fix mitochondrial dysfunction.  (1)  Rather than admit that there is nothing that they can do to fix the problem, those in the medical system deny that there is a problem.
  5. GREED, CORRUPTION and INFLUENCE.  The FDA and the EPA don’t require testing of drugs or environmental toxicants on mitochondria because the results would be incriminating, and those who would be incriminated have a massive amount of money and power.  It’s pretty simple, actually.

The ignorant, foolish doctor who “didn’t believe in mitochondrial disease” may want to note that:

“Mitochondrial function and behavior are central to the physiology of humans and, consequently, ‘mitochondrial dysfunction’ has been implicated in a wide range of diseases that encompass all aspects of medicine.”  (3)

It is time for those in the medical profession to stop ignoring the role of mitochondria in modern, chronic diseases.  The answers to preventing and fixing modern, chronic illnesses lie in the mitochondria.  Neither the questions nor the answers may be pleasant or convenient, but they are true and honest ones.  Cells don’t lie.  And the evidence against pharmaceutical and environmental toxicants that damage mitochondria is damning.

Post Script:  The author’s mitochondria were damaged by a prescription antibiotic, Cipro/Ciprofloxacin, a fluoroquinolone antibiotic.  Her blog, describing her story, and road to healing, is www.floxiehope.com.

Peer Reviewed Sources: 

  1. Toxicological Sciences, “Mitochondria as a Target of Environmental Toxicants
  2. Biochemical Society Transactions, “Mitochondrial Matirix Reactive Oxygen Species Production is Very Sensitive to Mild Uncoupling
  3. Cell, “Mitochondria:  In Sickness and In Health
  4. Molecular Interventions, “Mechanisms of Pathogenesis in Drug Hepatotoxicity Putting the Stress on Mitochondria
  5. Antimicrobial Agents and Chemotherapy, “Calcium Signals are Affected by Ciprofloxacin as a Consequence of Reduction of Mitochondrial DNA Content in Jurkat Cells
  6. International Journal of Clinical and Experimental Medicine, “Chronic Fatigue Syndrome and Mitochondrial Dysfunction
  7. Journal of Internal Medicine, “Chronic fatigue syndrome: assessment of increased oxidative stress and altered muscle excitability in response to incremental exercise
  8. Muscle and Nerve, “Mitochondrial Myopathy Mimicking Fibromyalgia Syndrome
  9. The Journal of Rheumatology.  Supplement., “The Muscle in Fibromyalgia – A Review of Swedish Studies
  10. PLoS One, “Clinical Symptoms in Fibromyalgia Are Better Associated to Lipid Peroxidation Levels in Blood Mononuclear Cells Rather than in Plasma
  11. Nature Precedings, “Oxidative Stress and Mitochondrial Injury in Chronic Multisymptom Conditions: From Gulf War Illness to Autism Spectrum Disorder
  12. Pathophysiology, “Oxidative Stress in Autism
  13. Journal of Childhood Neurology, “Developmental Regression and Mitochondrial Dysfunction in a Child with Autism”
  14. Journal of Toxicology and Environmental Health, “Evidence of Toxicity, Oxidative Stress, and Neuronal Insult in Autism
  15. Science Translational Medicine, “Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells
  16. Journal of Young Pharmacists, “Oxidative Stress Induced by Fluoroquinolones on Treatment for Complicated Urinary Tract Infections in Indian Patients
  17. American Journal of Cardiovascular Drugs, “Statin Adverse Effects: A Review of the Literature and Evidence for a Mitochondrial Mechanism
  18. BMC Medicine, “Chronic fatigue syndrome: Harvey and Wessely’s (bio)psychosocial model versus a bio(psychosocial) model based on inflammatory and oxidative and nitrosative stress pathways
  19. Biochemical Journal, “Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study
  20. Molecular Nutrition & Food Research, “Medication Induced Mitochondrial Damage and Disease
  21. Antimicrobial Agents and Chemotherapy, “Calcium Signals Are Affected by Ciprofloxacin as a Consequence of Reduction of Mitochondrial DNA Content in Jurkat Cells

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Awareness

30-Year Study Finds Weekly Use Of Disinfectants Greatly Increases Your Chances Of Lung Disease

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In Brief

  • The Facts:

    A 30-year study conducted by Harvard researchers and the French National Institute of Health and Medical Research determined that people who use disinfectants just once a week have a 22-32% of developing lung disease.

  • Reflect On:

    There are many other natural alternatives out there these days. Some are listed in the article, be sure to do your research!

One of the most versatile cleaning supplies in the home, bleach disinfects anything it comes into contact with and can not only clean every surface but remove stains from fabrics, too. Despite its cleaning power, we’ve also long heard of the effects such chemicals can have on our health and wellbeing. The labels on such products make some of these clear, explaining they are corrosive and can irritate  eyes, skin, and respiratory tract, often through simple inhalation. Despite these warnings signs, people continue to buy into this corporate propaganda.

As previously stated in an article of ours from 2013:

It is important to note that there is no FDA-type organization that regulates the cleaning products that are brought into your home. Instead groups such as the United States Environmental Protection Agency (EPA) make warnings of the use of Chlorine Bleach publicly available. Under the assumption that consumers will continue to use Chlorine Bleach within their households, the following safety precautions are widely recommended:

  • Dilute the chlorine bleach with water. The lower concentration poses a potentially lesser risk of unwanted exposure.
  • Wear a safety mask and rubber gloves when working with bleach as a preventative measure.
  • Only use chlorine bleach in a well ventilated area to allow for sufficient air flow and to prevent the unwanted gasses from remaining stationary in the working space.
  • Never mix chlorine bleach with any other household cleaners.

It’s unlikely people exercise these precautions when dealing with this chemical, and it’s also interesting to note that even more studies have come forward since then confirming these risks.


A new study has found that people who use disinfectants just once a week have a 22-32% increased chance of developing chronic obstructive pulmonary disease (COPD).

“COPD is the third leading cause of death in the United States. More than 11 million people have been diagnosed with COPD, but millions more may have the disease without even knowing it. COPD causes serious long-term disability and early death. At this time there is no cure, and the number of people dying from COPD is growing,” according to the American Lung Association.

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The 30-year study was conducted by Harvard University and the French National Institute of Health and Medical Research. This new study could potentially link COPD to specific cleaning chemicals, as two other studies in European populations showed that “working as a cleaner was associated with a higher risk of COPD,” according to Orianne Dumas, a researcher at Inserm. Dumas goes on to say, “Earlier studies have found a link between asthma and exposure to cleaning products and disinfectants at home, such as bleach and sprays, so it is important to investigate this further.”

In 1989, the Harvard researchers found 55,185 working female nurses in the U.S. who did not have COPD, then analyzed those who were still working in 2009 over the next eight years. Participants were given a questionnaire to determine which disinfectants they used most frequently and why they used them. The disinfectants included glutaraldehyde (a strong disinfectant used for medical instruments), bleach, hydrogen peroxide, alcohol, and quaternary ammonium compounds (known as “quats”). In addition to the questionnaire, they took into account factors such as age, weight and ethnicity.

During this period they found that 663 were diagnosed with the condition. “In our study population, 37% of nurses used disinfectants to clean surfaces on a weekly basis and 19% used disinfectants to clean medical instruments on a weekly basis,” says Dumas.

The study aims to highlight the lack of health guidelines when it comes to cleaning and disinfectants, especially in healthcare settings, and researchers hope their results will prompt further investigation and better safety precautions.

There are many substantial alternatives to bleach like vinegar or essential oils, and if you’d like to further rid your home of harsh chemicals, check out this article (click here).

We need more people like these researchers, who dedicate their time to ensuring our safety when it comes to items we have incorporated into our lifestyle and assume are safe, doing this kind of work. This information isn’t meant to scare anyone, especially those of us who actively use these materials, but rather to bring more awareness so that we can educate ourselves and make healthier choices. There are countless healthy and safe alternatives when it comes to what we clean with, what we wear, and what we eat. You have to play the role of researcher in your own life if you expect to make positive change, and by having an open mind, you allow yourself to accept opportunities that can further your growth, mentally, physically, and spiritually.

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Awareness

Alcohol Is Killing More People Than The Opioid Epidemic. So Why Aren’t We Talking About It?

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In Brief

  • The Facts:

    Alcohol related deaths are the third leading cause of preventable deaths in the US.

  • Reflect On:

    Should we be glamorizing the consumption of alcohol in the media and in advertisements? Is it time to get real about the potentially life threatening risks of this drug?

In recent years, we have been hearing a lot about the opioid epidemic that is sweeping the nation. The Center for Disease Control reported that over 47,000 people died in the United States alone from an opiate overdose in 2017, that is almost 5 times the amount of deaths caused by opiates in 1999. This is important, and yes it is good this is getting the attention that it deserves. However, in the same year, an estimated 88,000 people died from alcohol related causes — Did anyone hear about that?

Alcohol is the third leading cause of preventable death in the United States, the first is tobacco and the second is poor diet and minimal physical activity. Given this, why aren’t we talking about it? And why don’t we see warning labels on alcoholic beverages? Why are we promoting such a harmful substance? We certainly don’t see huge billboards with people in bikinis popping oxycontin or injecting heroin, because we are well aware that these substances are addictive and can cause harm, so again, why are we openly promoting alcohol? Especially to young people?

Is It Because It’s Legal?

Is it possible that alcohol related deaths do not garner as much of a cause for concern because it is legal, easily available and socially acceptable? Most likely. Alcohol sales reached $253.8 billion in the US in 2018 — this might also have something to do with it.

I’m not suggesting that criminalizing alcohol is a solution to this issue or anything, the same way I don’t see how it’s still against the law to use any drugs at all, regardless of how bad they are for you. I believe that we should have the say in how we treat ourselves and what we put into our bodies, not the government or a legal system. But instead of being portrayed as a harmful substance, like opiates, crystel meth, and crack are — alcohol is glamorized by the media; often being portrayed as sophisticated, fun, sexy and generally just the cool thing to do.

Alcohol Is Basically Encouraged In Our Society

There is no doubt about it, the use of alcohol is deeply ingrained in our culture. So much so, that choosing not to drink is often the more odd thing to do. People will always ask, oh, how come you’re not drinking? As opposed to other drugs, people won’t typically ask, oh why aren’t you smoking meth tonight? Or whatever it may be.

Binge drinking is practically expected on the weekends, and for many people it is a way to unwind, let loose and have fun after a long workweek. Many people justify their consumption this way insisting that it’s fine, because, I don’t drink every day. The thing about alcohol abuse is that it doesn’t have to be every day to be considered a problem or for the person to be considered an alcoholic.

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There are many ways we tend to justify our use, because the thought of giving it up entirely or admitting that we even have a problem can be extremely overwhelming — especially if our entire livelihoods are centered on it.

How Much Is Too Much?

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) created a web site called “Rethinking Drinking” to highlight the amount of misconceptions about what is considered “low-risk” and “high-risk” alcohol consumption. It turns out, more than three drinks in a day or more than seven drinks per week for women and four drinks per day or 14 drinks per week for men are considered “high-risk,” and these patterns can be detrimental both in the short and long-term.

Some people might have an attitude of, I don’t drink at all during the week, so I have all of my allotted alcoholic beverages on the weekend — however, for men consuming 5 or more drinks and for women consuming 4 or more drinks in about a 2 hour period is considered binge drinking.

Is It Time To ‘Rethink That Drink’?

Should we have more campaigns aimed to raise awareness about the potential harm caused by alcohol? Because it is legal it seems to have this view of also being safe, because our government officials and lawmakers always have our best interest at heart, right? 😉 But if we aren’t educating young people effectively on the potential risks associated with alcohol consumption, then perhaps there should be more of an effort to make the risks known on the packaging and even eliminating ads. In my opinion, it simply does not make sense to be legally allowed to advertise something that is so harmful — especially in such a glamorized way.

I don’t know what it’s like now for teens and if it is still considered “cool” to drink and if there is a ton of peer pressure around the whole thing. My hope is that this view will shift, young people will be made more aware of the risks and more people will find the courage to step away from what is no longer serving them or what’s not in their best interest.

Many health advocates and people that are very cautious with regards to what they are putting into their body are still completely overlooking alcohol as a harmful substance. Now, there is no judgment to anyone who chooses to drink, but I think it’s time to take a good hard look at these things and at least have the awareness behind it. Surely, it can be fun from time to time to relax, to loosen up, to be silly, but when we are relying on it to escape our unhappiness from our current situation, well then maybe it’s time to face these situations head on, rather than escape them and change whatever is encouraging us to reach for that glass of wine, whiskey or beer in the first place.

How Can We Support Others?

The fact of the matter remains, many people who drink can do so sparingly, not in excess and not very often. They have a handle on it and it doesn’t interfere with their lives in a negative way. However, for the ones who have struggled — with drinking too much, too frequently, with black outs, it can be difficult to even know if it’s a problem because of how acceptable it is in our society.

If someone says, no thanks I’m not drinking, don’t ask why, and instead try, right on! And no peer pressure. I’ve had problems with drinking, have quit and relapsed twice, currently I’m sober. Before I stopped drinking this time around I would open up to some people about it, questioning my use and whether or not it was harmful, many people would tell me, ahh don’t be so hard on yourself! We are allowed to enjoy life, or shut down from time to time if we need to. If someone is expressing to you that they are concerned they might have a drinking problem, don’t make them second guess themselves, if they are opening up about it please try to support them. We don’t always know what others are going through — apparently even if they flat out tell us. This may also challenge our own relationship with alcohol, but if you can keep that separate.

Do You Have A Problem?

If you are concerned that you might have a drinking problem, you probably do. Keeping in mind that having a problem with alcohol doesn’t necessarily make you an alcoholic. You may have a problem with alcohol if you can identify with any of the following scenarios:

  1. Spending a lot of time obtaining, using, and recovering from the effects of alcohol.
  2. Cravings, or a strong desire to use alcohol.
  3. Being unable to cut down on alcohol use despite a desire to do so.
  4. Continuing to abuse alcohol despite negative interpersonal or social problems that are likely due to alcohol use.
  5. Using alcohol in physically dangerous situations (such as driving or operating machinery).
  6. Drinking more or for a longer time than originally intended.
  7. Continuing to abuse alcohol despite the presence of a psychological or physical problem that is probably due to alcohol use.
  8. Being unable to fulfill major obligations at home, work, or school because of alcohol use.
  9. Giving up previously enjoyed social, occupational, or recreational activities because of alcohol use.
  10. Having a tolerance (i.e. needing to drink increasingly large or more frequent amounts of alcohol to achieve the desired effect).
  11. Developing symptoms of withdrawal when efforts are made to stop using alcohol.

A great way to get things in check is to commit to a period of time without any alcohol consumption and monitor how you feel, what you accomplish, and if you feel uplifted. You may need to ask your friends to support you during this time and have some sober activities prepared! Board games, cards, movies, sports, hiking — all these things can be great sober fun!

If your problem is more severe than this, or you are needing help in any way, reach out to a trusted friend or family member or you may benefit from your local Alcoholics Anonymous meetings for a whole slough of support and resources. If that’s not your jam, check out Hello Sunday Morning for assistance in moderating your use.

My hope is that in the near future it will be more common not to drink and doing so will be more like taking a drug, or having an experience that is typically out of the ordinary.

It is never too late to make a change, first step is to get really honest with yourself…

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Alternative News

Joe Rogan May Take Down The Original Criticism Of “The Game Changers” Documentary

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In Brief

  • The Facts:

    Joe Rogan recently had James Wilks, the maker of "The Game Changers" documentary on to discuss the benefits of a plant base diet and to refute a previous episode where Chris Kresser debunked it.

  • Reflect On:

    When it comes to health, it's important sometimes to suspend what we believe and have been made to believe, and simply look at the information from a neutral perspective.

Joe Rogan has long ‘criticized’ vegans in various ways, and has also emphasized his belief that one cannot be optimally healthy on a vegan diet. He’s done this a number of times, which was hard for some onlookers to watch and listen to who have educated themselves on plant-based diets. Until recently, Rogan mainly focused on guests that were geared towards promoting meat-eating as optimal, and there’s nothing wrong with that, but a balance of understanding and information can go a long way to educating people.

One of the most recent examples of Joe Rogan and his guest ‘”debunking” a plant-based diet came from a critique of a recent documentary that is now airing on Netflix, called “The Game Changers,” made by filmmaker, James Wilks – a retired English mixed martial artist. The film was executively produced by James Cameron, and features interviews with the top scientists and doctors in their field who present an abundance of research and publications showing the benefits of a plant-based diet.

Not long ago, health coach and author Chris Kresser came on the “Joe Rogan Experience” after the documentary received a lot of attention, and the title of the podcast was titled: “Chris Kresser Debunks ‘The Game Changers Documentary.’

For someone like my self who has done a lot of research into the topic, it was frustrating to listen to it given the fact that it was quite clear, for me and others who had actually done thorough research from a neutral standpoint, that Kresser wasn’t really addressing all the facts, and was simply a big believer in what he was saying without even examining the information on the other side.

The challenge is, Rogan’s podcast was listened to by millions of people, and many came away actually believing the information that was said in the original debunking episode – information we later find out was completely incorrect. These types of episodes that massively mislead people are not just an issue with people who have large followings discussing vegan diets and health, but it’s a big issue with many other topics. This is why it was great that Rogan decided to have James Wilks on for a chance to defend his documentary, and the truth is he absolutely destroyed Kresser’s claims that were presented as facts in the previous podcast with Rogan. The best part was Kresser was on the show as well so he had a chance to truly make sure everyone was on the same page.

Wilks addressed every single criticism made by Kresser in the previous episode, from topics such as B12, protein amount, and protein quality, among many others. He also brought up the fact that we shouldn’t be listening to people like Kresser on such topics, but should be relying on properly published peer reviewed research that’s repeatable, non-industry conflicting research, as well as information that comes from the world’s leading scientists in the field of biology and nutrition, many of whom were presented in the Game Changers documentary. Or, people like Wilks, who have throughout done their research.  This episode really exposes how Kresser is not accurate or factual in his position on this topic, an important note for his followers.

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It’s important to keep in mind that not everything Kresser said previously had time to be addressed in this podcast, but it could have been. 100 percent of Kresser’s criticisms that were addressed were 100 percent completely debunked by Wilks, so much so that this is what Joe Rogan had to say via an Instagram post:

If interested, you can watch The Game Changers documentary on Netflix, and check out the podcast in question below.

Some Quotes From The Game Changers Documentary

One of these experts is Dr. Christina Warinner, who earned her Ph.D. from Harvard University in 2010 and received her postdoctoral training at the University of Zurich (2010-2012) and the University of Oklahoma (2012-2014). She became a Presidential Research Professor and Assistant Professor of Anthropology at the University of Oklahoma in 2014, and is currently a Leader in Microbiome Sciences at the Max Planck Institute for the Science of Human History.

Her work has led to some very interesting findings and conclusions:

“Humans do not have any specialized genetic anatomical or physiological adaptations to meat consumption. By contrast, we have many adaptations to plant consumption.” (The Game Changers documentary)

She goes deeper in her presentation at the 2016 International Conference on Nutrition in Medicine, and in this TEDX talk she gave a number of years ago.

Gradual increases in brain sizes of early humans have also been attributed to meat, but research is showing that “because there is not a very strong match between meat consumption and gradual increases in brain size, scientists have looked to other options. And given that plant foods are such an important part of modern humans that hunt and gather foods, the money is on plant foods and shift in the kinds of plant foods as being the major driving factor in increasing brain size.” – Nathaniel J. Dominy

“We have a brain, that just is desperate for glucose. It’s such a fussy organ, that’s the only thing it really takes in for energy. Well, meat is not a very good source of glucose, to have a big brain like this you need to eat something different. And the most efficient way to get glucose is to eat carbohydrates.” – Dr. Mark Thomas, geneticist, University College, London (The Game Changers documentary)

With overwhelming scientific evidence to many of the most common deadly diseases, I discovered that the meat, egg, and dairy industries have been engaged in a covert response, funding studies that deny this evidence while burying their involvement in the fine print. One of the hired guns paid to conduct these studies is Exponent, INC. A company whose research was used by the Tobacco industry to deny the connection between second hand smoke and cancer. For more than 50 years, Exponent has generated studies that challenge the health-risks of everything from asbestos, arsenic and and mercury, to animal foods.” – James Wilks,  “The Game Changers” documentary

“The formula, works beautifully for people selling food, it works beautifully for people selling drugs to treat the diseases that bad food causes, and it works beautifully for the media, which can give us a new story about diet, everyday. But despite the appearance in our media of confusion, there’s massive global consensus about the fundamentals of a health-promoting, and it’s a diet that every time… In every population, every kind of research, it’s a plant food predominant diet, every time.” – Dr. David Katz, Founding Director of Yale University Prevention Research Center (The Game Changers documentary)

A Related CE Articles With More Information: 

Humans Are Not Designed To Eat Meat – Leading Microbiome Scientist Explains

12,000 Doctors Urge The FDA to put Cancer Warnings on Cheese 

Scientist: Milk From Cows Has “The Most Relevant Carcinogen Ever Identified” & “Turns on Cancer”

Scientist Explains How Cow’s Milk Leeches Calcium From Your Bones & Makes Them Weaker

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