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The Importance Of Making Compassionate Corporations

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Pradeep B. Deshpande is Professor Emeritus and a former chair of the Department of Chemical Engineering at the University of Louisville, a visiting professor of Management at Gatton College of Business & Economics at University of Kentucky and founder, president and CEO of Louisville-based Six Stigma and Advanced Controls, Inc. (SAC).

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He has done some important research that has compassion, love, cooperation and understanding as the core for world transformation. He recently reached out to Collective Evolution and we agreed to share his work with the world, so check it out: Internal Excellence Boosts Business Performance.

At the conclusion of his first interview with the New York Times (21 February 2014), Satya Nadella, the newly appointed CEO of Microsoft remarked, “One of the things I am fascinated about generally is the rise and fall of everything, from civilizations, to families, to companies. We all know the mortality of companies is less than human beings. There are few examples of even 100-year old companies. For us to be a 100- year-old company where people find meaning at work, that is the quest”.

The scientific framework for individual, organizational, national, and world transformation this author has developed in recent years is the path forward to realize Mr. Nadella’s vision. Rise and decline of civilizations follow certain natural laws the author articulated over two decades ago. However, there is nothing in these laws to suggest that with deliberate intent, emerging nations such as India cannot rise faster, or nations currently in decline such as Greece cannot change direction, or for that matter, developed nations such as the United States cannot keep decline at bay longer. Furthermore, these laws apply to populations at large placing no limit whatsoever on an individual aspiring to rise to the highest level possible for a human being regardless of where on the rise and decline curve his or her civilization happens to be. These ideas extend to companies as well.

Excellence comprises of two components: Excellence of the external and excellence of the internal (the definitions are at the end of the article). It is essential for companies aspiring for long term excellence to embrace both. One without the other is insufficient. The US-developed six sigma framework is the wherewithal for the excellence of the external while ancient Indian wisdom is the home of the excellence of the internal. So powerful is the phenomenon of rise and decline that the very culture who has understood it for millennia, is unable escape its effects.

Until recently, the author had maintained six sigma was the only way for individuals, organizations, and nations to emerge as their best. This assertion is only partly correct. Strong evidence has become available which suggests that in the absence of internal excellence, six sigma performs (for that matter, any other quality initiative be it TQM, Kaizen, Lean, CMM Level 5, Balanced Score Card, etc.) will fall far short of expectations. Put it another way, in the presence of internal excellence, six sigma programs will lead to exemplary performance. By extension, the absence of both components of excellence is an invitation of disaster.

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In the following paragraphs three examples are presented to substantiate the claim of a strong link of internal excellence to exemplary performance: (1) Mumbai’s Dabbawallahs, (2) The 2013 Kumbh Mela, and (3) Gamarra Businesses of Lima, Peru.

1. Mumbai’s Dabbawallahs. They are an internationally-renowned group of 5,000 lunchbox delivery boys reportedly with an average eighth grade education who deliver some 150,000 lunch boxes a day in Mumbai, India. Each day, the lunch boxes containing home-cooked meals are picked up from the residences of customers who commute into Mumbai and delivered to their offices throughout the city. The lunch boxes are picked up from customers’ homes long after they have gone to work. After lunch, the process is reversed. Lunch box delivery time is 12:30 PM and the empty boxes are picked up at 1:30 PM for the return journey and delivered before the customers return. The Dabbawallahs know that customer satisfaction issues arise if a customer receives someone else’s lunch box or if it does not arrive on time.

These Dabbawallah    reportedly make one mistake every two months or so. That’s an error rate of one in 8 million deliveries. So impressed was Britain’s Prince Charles that he paid them a personal visit to witness their operations. The price for this exemplary service, $3 per month. In the 1998 article, Forbes expressed their feelings this way: Superb service and charity too. Can anyone ask for more? The Dabbawallahs themselves believe, Work is worship. The author has been taking up this case study in his six sigma training programs for over a decade challenging students that such a great performance is possible when six sigma practices are followed. There is no doubt the performance is outstanding and that the process is six sigma compliant but the claim now is that such performance is impossible without a sufficiently high S component.

2. The 2013 Kumbh Mela. Kumbh Mela, believed to be the largest religious gathering of humans on earth is held at in the city of Allahabad in the state of Uttar Pradesh in India every twelve years on the banks of the confluence of the holy rivers Ganga, Yamuna, and the mythical Saraswati. Most recently the Mela was celebrated during the first quarter of 2013. The Financial Times carried an interesting article on March 1, 2013 written by Victor Mallet titled, “Pop-up Mega City is a Lesson in Logistics for India.”

Said the Financial Times, To somebody who does projects, the tent city is like a mega-refugee camp that comes up overnight and gets sustained and managed for two months with people filtering in and out at a rate of millions a day. It’s managed by the Uttar Pradesh State government. If somehow we could translate that capacity to day-to-day business, you could transform UP. It’s really a powerful thought.” Uttar Pradesh is often seen as the epitome of all that is wrong with India. With a population of over 200 million – larger than Brazil’s – the state is notoriously corrupt and inefficient. Take sanitation. In the decade to 2011, the UP government reported steadily rising construction of latrines in rural areas with the help of $600 million in public funds. But the 2011 census showed that almost no toilets had actually been built. Most of the money was stolen, leaving tens of thousands of children to die each year as a result of diarrhea spread by what one aid worker called “appalling” sanitation. There are few such problems at the Kumbh Mela, however.

Mr. Onno Ruhl, Head of the World Bank in India, who visited the Kumbh Mela was so moved by the operations that he decided to bathe in the Ganges himself. He called it an incredible logistical operation.

Said Mr. Ruhl in the Financial Times article, “The city on the sandbanks, soon to be dismantled before the river floods, “has water, sanitation, power, and solid-waste management, everything, actually, that many Indian cities lack”

Harvard researchers described it as “a pop-up mega city”. The bureaucrats and workers from Uttar Pradesh, India’s most populous and one of the poorest states took less than three months to build a tent city for 2 million residents complete with hard roads, toilets, running water, electricity, food shops, garbage collection, and well-manned police stations. This year’s event attracted millions of pilgrims from across India who came to wash away their sins in the Ganges at its confluence with the Yamuna. Over its two months to mid-March, the Mela attracted 80 -100 million visitors, with up to 30 million attempting to bathe in the river on February 10 alone, officials say. Precise numbers are hard to come by but the devotees and foreign visitors are generally full of praise for the organizers of what is arguably the largest gathering of humans on earth. Apart from a February 10 stampede at the nearby Allahabad railway station in which 36 were killed, the Kumbh Mela itself has so far gone off smoothly. Fresh water comes out of the taps, toilets are disinfected, trained police carefully shepherd the crowds to the bathing areas, and the lights come on at night. Devesh Chaturvedi, Divisional commissioner of Allahabad is proud of the “huge task” that he and perhaps 100,000 workers completed in organizing the festival. He mentions 165 km of roads on the sand made of steel plates, 18 pontoon bridges, 560 km of water supply lines, 670 km of electricity lines, 22,500 street lights and 200,000 electricity connections, as well as 275 food shops for essential supplies such as flour, rice, milk and cooking gas. Mr. Chaturvedi agrees there is a contrast between the successful provision of these services and the way life continues in the rest of the state, and has two explanations. First, the authorities ensure that all those working on the project are accountable for their actions and the money they spend. Second, those involved are highly motivated. “They feel it’s a real service to all these pilgrims who have come here, the sadhus

[holy men] and the seers, so it’s a sort of mission which motivates them to work extra, despite difficult working conditions.”

In the concluding thoughts on the article, Victor writes, a question on the minds of both Indians and foreigners is: How? Why? Or rather: if the authorities can build infrastructure so efficiently for this short but very large festival and its instant city, why can they not do the same for permanent villages and towns? We trust the answer is clear to the readers of this article. This level of performance would have been impossible in the absence of a sufficiently high level of consciousness on the part of both the workers and devotees.

3. Gamarra Businesses of Lima Peru. Gamarra businesses span 34 blocks around Hipólito Unanue and Agustín Gamarra streets in La Victoria region of Lima, Peru. Gamarra has 25,000 businesses that employ 100,000 workers, generating $1.2 billion in revenue annually. These businesses import textiles from several countries at competitive prices. Depending on the size, individual entrepreneurs are set up to handle a certain volume of business. However, agreements with other entrepreneurs allow them to handle orders of any size up to the total capacity of all entrepreneurs in Gamarra. This arrangement assures B-to-B customers of not only high quality and low cost but also a quick turnaround.

Depending on season, anywhere between 150,000 and 600,000 visit Gamarra every day. Seventy percent of visitors reportedly purchase something or the other. Gamarra entrepreneurs are renowned and widely respected among both business customers and end-use consumers. Their textile products are known for high quality and low cost.

The author visited Gamarra in 2008 with his former doctoral student, Dr. Roberto Z. Tantalean to study their operations from a lean six sigma perspective. Like their counterparts in Mumbai, they are not a highly educated workforce either. That theirs is a lean six sigma operation is absolutely clear; nothing goes to waste and there is very high level of customer satisfaction. A clue to their higher S component is their motto, Compete but cooperate!

So, how does a company aspiring to replicate such exemplary performance proceed? There are two approaches: A conscious approach wherein one watches over their S, R, T components to be sure that S stays up and nudges higher and R, T stay low and nudge lower. The second approach is a process whose side-effect is a rise in the S component. Meditation is one such process. Investigators have shown that meditation leads to more compassion and evidence is emerging that profits at compassionate companies are far higher than those at other companies. In his papers on a scientific framework for world transformation, the author explains these concepts in detail. In his author’s view this is the way to sustain excellence in the long term that Mr. Nadella was referring to, there is no other way.

Definitions and Note.

  •   Rising level of Internal Excellence equates to higher S, R, T Level of Consciousness
  •   S: Truthfulness, honesty, steadfastness, equanimity; study
  •   R: Attachment, bravery, ego, ambition, greed, desire to live;
  •   T: Lying, cheating, causing injury in words or deeds, sleep.
  •   Minimum S, R, T required for life.
  •   S component strongly correlates with positive emotions (Unconditioned love, kindness, empathy, compassion, gratitude, forgiveness, etc.)
  •   Excessive R, T components strongly correlate with negative emotions (Anger, hostility, hatred, irritation, sorrow, fear).
  •   External Excellence refers to the wherewithal of doing all that we do from wake up time to bedtime including all that we do at work in the best possible manner.

Further Reading

  1. [1]  Deshpande, P. B., Internal Excellence Boosts Business Performance, 2014.
  2. [2]  Deshpande, P. B., Aroskar, S. A., Bhavsar, S. N., and Kulkarni, B. D., Mind Over Matter: Investigation of Materialization of Intentions, Journal of Consciousness Exploration & Research, 5, 2, February 2014.
  3. [3]  Deshpande, P. B., Can the excellence of the Internal be Measured, Journal of Consciousness Exploration and Research, 4, 11, November 2013.
  4. [4]  Deshpande, P. B., Scientific Framework for Individual, Organizational, National, and Global Transformation, 17th Annual Conference on Science, Information, and Consciousness, St. Petersburg, Russia, July 6 8, 2013.
  5. [5]  Deshpande, P. B., Compassion, Performance, and Programs of Excellence, Journal of Consciousness Exploration and Research, 4, 4, April 2013.
  6. [6]  Deshpande, P. B., Science of Compassion, Journal of Consciousness Exploration and Research, 3, 9, October

     

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Awareness

Epigenetic Memories Are Passed Down 14 Successive Generations, Game-Changing Research Reveals

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In Brief

  • The Facts:

    It's amazing how much information can be passed on to our offspring. Scientist have discovered that our DNA has memories, and these can also be passed down. We are talking about thoughts, feelings, emotions and perceptions.

  • Reflect On:

    Biological changes are shaped by our environment, as well as our thoughts, feelings, emotions and reaction to that environment. Our DNA can be changed with belief, the placebo is a great example. Thoughts feelings and emotions are huge in biology.

This article was written by the Greenmedinfo research group, from Greenmedinfo.com. Posted here with permission.

Until recently, it was believed that our genes dictate our destiny. That we are slated for the diseases that will ultimately beset us based upon the pre-wired indecipherable code written in stone in our genetic material. The burgeoning field of epigenetics, however, is overturning these tenets, and ushering in a school of thought where nurture, not nature, is seen to be the predominant influence when it comes to genetic expression and our freedom from or affliction by chronic disease.

Epigenetics: The Demise of Biological Determinism

Epigenetics, or the study of the physiological mechanisms that silence or activate genes, encompasses processes which alter gene function without changing the sequence of nucleotide base pairs in our DNA. Translated literally to mean “in addition to changes in genetic sequence,” epigenetics includes processes such as methylation, acetylation, phosphorylation, sumolyation, and ubiquitylation which can be transmitted to daughter cells upon cell division (1). Methylation, for example, is the attachment of simple methyl group tags to DNA molecules, which can repress transcription of a gene when it occurs in the region of a gene promoter. This simple methyl group, or a carbon bound to three hydrogen molecules, effectively turns the gene off.

Post-translational modifications of histone proteins is another epigenetic process. Histones help to package and condense the DNA double helix into the cell nucleus in a complex called chromatin, which can be modified by enzymes, acetyl groups, and forms of RNA called small interfering RNAs and microRNAs (1). These chemical modifications of chromatin influence its three-dimensional structure, which in turn governs its accessibility for DNA transcription and dictates whether genes are expressed or not.

We inherit one allele, or variant, of each gene from our mother and the other from our father. If the result of epigenetic processes is imprinting, a phenomenon where one of the two alleles of a gene pair is turned off, this can generate a deleterious health outcome if the expressed allele is defective or increases our susceptibility to infections or toxicants (1). Studies link cancers of nearly all types, neurobehavioral and cognitive dysfunction, respiratory illnessesautoimmune disorders, reproductive anomalies, and cardiovascular disease to epigenetic mechanisms (1). For example, the cardiac antiarrhythmic drug procainamide and the antihypertensive agent hydralazine can cause lupus in some people by causing aberrant patterns of DNA methylation and disrupting signalling pathways (1).

Genes Load the Gun, Environment Pulls the Trigger

Pharmaceuticals, however, are not the only agents that can induce epigenetic disturbances. Whether you were born via vaginal birth or Cesarean section, breastfed or bottle-fed, raised with a pet in the house, or infected with certain childhood illnesses all influence your epigenetic expression. Whether you are sedentary, pray, smoke, mediate, do yoga, have an extensive network of social support or are alienated from your community—all of your lifestyle choices play into your risk for disease operating through mechanisms of epigenetics.

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In fact, the Centers for Disease Control (CDC) states that genetics account for only 10% of disease, with the remaining 90% owing to environmental variables (2). An article published in the Public Library of Science One (PLoS One) entitled “Genetic factors are not the major causes of chronic diseases” echoes these claims, citing that chronic disease is only 16.4% genetic, and 84.6% environmental (3). These concepts make sense in light of research on the exposome, the cumulative measure of all the environmental insults an individual incurs during their life course that determines susceptibility to disease (4)

In delineating the totality of exposures to which an individual is subjected over their lifetime, the exposome can be subdivided into three overlapping and intertwined domains. One segment of the exposome called the internal environment is comprised of processes innate to the body which impinge on the cellular milieu. This encompasses hormones and other cellular messengers, oxidative stress, inflammation, lipid peroxidation, bodily morphology, the gut microbiotaaging and biochemical stress (5).

Another portion of the exposome, the specific external environment, consists of exposures including pathogens, radiation, chemical contaminants and pollutants, and medical interventions, as well as dietary, lifestyle, and occupational elements (5). At an even broader sociocultural and ecological level is the segment of the exposome called the general external environment, which may circumscribe factors such as psychological stress, socioeconomic status, geopolitical variables, educational attainment, urban or rural residence, and climate (5).

Transgenerational Inheritance of Epigenetic Change: Endocrine Disruptors Trigger Infertility in Future Generations

Scientists formerly speculated that epigenetic changes disappear with each new generation during gametogenesis, the formation of sperm and ovum, and after fertilization. However, this theory was first challenged by research published in the journal Science which demonstrated that transient exposure of pregnant rats to the insecticide methoxychlor, an estrogenic compound, or the fungicide vinclozolin, an antiandrogenic compound, resulted in increased incidence of male infertility and decreased sperm production and viability in 90% of the males of four subsequent generations that were tracked (1).

Most notably, these reproductive effects were associated with derangements in DNA methylation patterns in the germ line, suggesting that epigenetic changes are passed on to future generations. The authors concluded, “The ability of an environmental factor (for example, endocrine disruptor) to reprogram the germ line and to promote a transgenerational disease state has significant implications for evolutionary biology and disease etiology” (6, p. 1466). This may suggest that the endocrine-disrupting, fragrance-laden personal care products and commercial cleaning supplies to which we are all exposed may trigger fertility problems in multiple future generations.

Transgenerational Inheritance of Traumatic Episodes: Parental Experience Shapes Traits of Offspring

In addition, traumatic experiences may be transmitted to future generations via epigenetics as a way to inform progeny about salient information needed for their survival (7). In one study, researchers wafted the cherry-like chemical acetophenone into the chambers of mice while administering electric shocks, conditioning the mice to fear the scent (7). This reaction was passed onto two successive generations, which shuddered significantly more in the presence of acetophenone despite never having encountered it compared to descendants of mice that had not received this conditioning (7).

The study suggests that certain characteristics of the parental sensory environment experienced before conception can remodel the sensory nervous system and neuroanatomy in subsequently conceived generations (7). Alterations in brain structures that process olfactory stimuli were observed, as well as enhanced representation of the receptor that perceives the odor compared to control mice and their progeny (7). These changes were conveyed by epigenetic mechanisms, as illustrated by evidence that the acetophenone-sensing genes in fearful mice were hypomethylated, which may have enhanced expression of odorant-receptor genes during development leading to acetophenone sensitivity (7).

The Human Experience of Famine and Tragedy Spans Generations

The mouse study, which illustrates how germ cells (egg and sperm) exhibit dynamic plasticity and adaptability in response to environmental signals, is mirrored by human studies. For instance, exposures to certain stressors such as starvation during the gestational period are associated with poor health outcomes for offspring. Women who undergo famine before conception of her offspring have been demonstrated to give birth to children with lower self-reported mental health and quality of life, for example (8).

Studies similarly highlight that, “Maternal famine exposure around the time of conception has been related to prevalence of major affective disorders, antisocial personality disorders, schizophrenia, decreased intracranial volume, and congenital abnormalities of the central nervous system” (8). Gestational exposure to the Dutch Famine of the mid-twentieth century is also associated with lower perceived health (9), as well as enhanced incidence of cardiovascular disease, hypertension, and obesity in offspring (8). Maternal undernourishment during pregnancy leads to neonatal adiposity, which is a predictor of future obesity (10), in the grandchildren (11).

The impact of epigenetics is also exemplified by research on the intergenerational effects of trauma, which illuminates that descendants of people who survived the Holocaust exhibit abnormal stresshormone profiles, and low cortisol production in particular (12). Because of their impaired cortisol response and altered stress reactivity, children of Holocaust survivors are often at enhanced risk for post-traumatic stress disorder (PTSD), anxiety, and depression (13).

Intrauterine exposure to maternal stress in the form of intimate partner violence during pregnancy can also lead to changes in the methylation status of the glucocorticoid receptor (GR) of their adolescent offspring (14). These studies suggest that an individual’s experience of trauma can predispose their descendants to mental illness, behavioral problems, and psychological abnormalities due to “transgenerational epigenetic programming of genes operating in the hypothalamic-pituitary-adrenal axis,” a complex set of interactions among endocrine glands which determine stress response and resilience (14).

Body Cells Pass Genetic Information Directly Into Sperm Cells

Not only that, but studies are illuminating that genetic information can be transferred through the germ line cells of a species in real time. These paradigm-shifting findings overturn conventional logic which postulates that genetic change occurs over the protracted time scale of hundreds of thousands or even millions of years. In a relatively recent study, exosomes were found to be the medium through which information was transferred from somatic cells to gametes.

This experiment entailed xenotransplantation, a process where living cells from one species are grafted into a recipient of another species. Specifically, human melanoma tumor cells genetically engineered to express genes for a fluorescent tracer enzyme called EGFP-encoding plasmid were transplanted into mice. The experimenters found that information-containing molecules containing the EGFP tracer were released into the animals’ blood (15). Exosomes, or “specialized membranous nano-sized vesicles derived from endocytic compartments that are released by many cell types” were found among the EGFP trackable molecules (16, p. 447).

Exosomes, which are synthesized by all plant and animal cells, contain distinct protein repertoires and are created when inward budding occurs from the membrane of multivesicular bodies (MVBs), a type of organelle that serves as a membrane-bound sorting compartment within eukaryotic cells (16). Exosomes contain microRNA (miRNA) and small RNA, types of non-coding RNA involved in regulating gene expression (16). In this study, exosomes delivered RNAs to mature sperm cells (spermatozoa) and remained stored there (15).

The researchers highlight that this kind of RNA can behave as a “transgenerational determinant of inheritable epigenetic variations and that spermatozoal RNA can carry and deliver information that cause phenotypic variations in the progeny” (15). In other words, the RNA carried to sperm cells by exosomes can preside over gene expression in a way that changes the observable traits and disease risk of the offspring as well as its morphology, development, and physiology.

This study was the first to elucidate RNA-mediated transfer of information from somatic to germ cells, which fundamentally overturns what is known as the Weisman barrier, a principle which states that the movement of hereditary information from genes to body cells is unidirectional, and that the information transmitted by egg and sperm to future generations remains independent of somatic cells and parental experience (15).

Further, this may bear implications for cancer risk, as exosomes contain vast amounts of genetic information which can be source of lateral gene transfer (17) and are abundantly liberated from tumor cells (18). This can be reconciled with the fact that exosome-resembling vesicles have been observed in various mammals (15), including humans, in close proximity to sperm in anatomical structures such as the epididymis as well as in seminal fluid (19). These exosomes may thereafter be propagated to future generations with fertilization and augment cancer risk in the offspring (20).

The researchers concluded that sperm cells can act as the final repositories of somatic cell-derived information, which suggests that epigenetic insults to our body cells can be relayed to future generations. This notion is confirmatory of the evolutionary theory of “soft inheritance” proposed by French naturalist Jean-Baptiste Lamarck, whereby characteristics acquired over the life of an organism are transmitted to offspring, a concept which modern genetics previously rejected before the epigenetics arrived on the scene. In this way, the sperm are able to spontaneously assimilate exogenous DNA and RNA molecules, behaving both as vector of their native genome and of extrachromosomal foreign genetic material which is “then delivered to oocytes at fertilization with the ensuing generation of phenotypically modified animals” (15).

Epigenetic Changes Endure Longer Than Ever Predicted

In a recent study, nematode worms were manipulated to harbor a transgene for a fluorescent protein, which made the worms glow under ultraviolet light when the gene was activated (21). When the worms were incubated under the ambient temperature of 20° Celsius (68° Fahrenheit), negligible glowing was observed, indicating low activity of the transgene (21). However, transferring the worms to a warmer climate of 25°C (77° F) stimulated expression of the gene, as the worms glowed brightly (21).

In addition, this temperature-induced alteration in gene expression was found to persist for at least 14 generations, representing the preservation of epigenetic memories of environmental change across an unprecedented number of generations (21). In other words, the worms transmitted memories of past environmental conditions to their descendants, through the vehicle of epigenetic change, as a way to prepare their offspring for prevailing environmental conditions and ensure their survivability.

Future Directions: Where Do We Go From Here?

Taken cumulatively, the aforementioned research challenges traditional Mendelian laws of genetics, which postulate that genetic inheritance occurs exclusively through sexual reproduction and that traits are passed to offspring through the chromosomes contained in germ line cells, and never through somatic (bodily) cells. Effectively, this proves the existence of non-Mendelian transgenerational inheritance, where traits separate from chromosomal genes are transmitted to progeny, resulting in persistent phenotypes that endure across generations (22).

This research imparts new meaning to the principle of seven generation stewardship taught by Native Americans, which mandates that we consider the welfare of seven generations to come in each of our decisions. Not only should we embody this approach in practices of environmental sustainability, but we would be wise to consider how the conditions to which we subject our bodies—the pollution and toxicants which permeate the landscape and pervade our bodies, the nutrient-devoid soil that engenders micronutrient-poor food, the disruptions to our circadian rhythm due to the ubiquity of electronic devices, our divorce from nature and the demise of our tribal affiliations—may translate into ill health effects and diminished quality of life for a previously unfathomed number of subsequent generations.

Hazards of modern agriculture, the industrial revolution, and contemporary living are the “known or suspected drivers behind epigenetic processes…including heavy metals, pesticides, diesel exhaust, tobacco smoke, polycyclic aromatic hydrocarbons, hormones, radioactivity, viruses, bacteria, and basic nutrients” (1, p. A160). Serendipitously, however, many inputs such as exercise, mindfulness, and bioactive components in fruits and vegetables such as sulforaphane in cruciferous vegetables, resveratrol from red grapes, genistein from soy, diallyl sulphide from garlic, curcumin from turmeric, betaine from beets, and green tea catechin can favorably modify epigenetic phenomena “either by directly inhibiting enzymes that catalyze DNA methylation or histone modifications, or by altering the availability of substrates necessary for those enzymatic reactions” (23, p. 8).

This quintessentially underscores that the air we breathe, the food we eat, the thoughts we allow, the toxins to which we are exposed, and the experiences we undergo may persevere in our descendants and remain in our progeny long after we are gone. We must be cognizant of the effects of our actions, as they elicit a ripple effect through the proverbial sands of time.

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References

1. Weinhold, B. (2006). Epigenetics: The Science of Change. Environmental Health Perspectives, 114(3), A160-A167.

2. Centers for Disease Control and Prevention. (2014). Exposome and Exposomics. Retrieved from https://www.cdc.gov/niosh/topics/exposome/

3. Rappaport, S.M. (2016). Genetic factors are not the major causes of chronic diseases. PLoS One, 11(4), e0154387.

4. Vrijheid, M. (2014). The exposome: a new paradigm to study the impact of environment on health. Thorax, 69(9), 876-878. doi: 10.1136/thoraxjnl-2013-204949.

5. Wild, C.P. (2012). The exposome: from concept to utility. International Journal of Epidemiology, 41, 24–32. doi:10.1093/ije/dyr236

6. Anway, M.D. et al. (2005). Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science, 308(5727), 1466-1469.

7. Dias, B.G., & Ressler, K.J. (2014). Parental olfactory experience influences behavior and neural structure in subsequent generations. Nature Neuroscience, 17(1), 89-98.

8. Stein, A.D. et al. (2009). Maternal exposure to the Dutch Famine before conception and during pregnancy: quality of life and depressive symptoms in adult offspring. Epidemiology, 20(6), doi:  10.1097/EDE.0b013e3181b5f227.

9. Roseboom, T.J. et al. (2003). Perceived health of adults after prenatal exposure to the Dutch famine. Paediatrics Perinatal Epidemiology, 17, 391–397.

10. Badon, S.E. et al. (2014). Gestational Weight Gain and Neonatal Adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Study-North American Region. Obesity (Silver Spring), 22(7), 1731–1738.

11. Veenendaal, M.V. et al. (2013). Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine. BJOG, 120(5), 548-53. doi: 10.1111/1471-0528.

12. Yehuda, R., & Bierer, L.M. (2008). Transgenerational transmission of cortisol and PTSD risk. Progress in Brain Research, 167, 121-135.

13. Aviad-Wilcheck, Y. et al. (2013). The effects of the survival characteristics of parent Holocaust survivors on offsprings’ anxiety and depression symptoms. The Israel Journal of Psychiatry and Related Sciences, 50(3), 210-216.

14. Radke, K.M. et al. (2011). Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor. Translational Psychiatry, 1, e21. doi: 10.1038/tp.2011.21.

15. Cossetti, C. et al. (2014). Soma-to-Germline Transmission of RNA in Mice Xenografted with Human Tumour Cells: Possible Transport by Exosomes. PLoS One, https://doi.org/10.1371/journal.pone.0101629.

16. Zomer, A. et al. (2010). Exosomes: Fit to deliver small RNA. Communicative and Integrative Biology, 3(5), 447–450.

17. Balaj, L. et al. (2011) Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences. Natural Communications, 2, 180.

18. Azmi, A.S., Bao, B., & Sarkar, F.H. (2013). Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. Cancer Metastasis Review, 32, 623-643

19. Poliakov, A. et al. (2009). Structural heterogeneity and protein composition of exosomes-like vesicles (prostasomes) in human semen. Prostate, 69, 159-167.

20. Cheng, R.Y. et al. (2004) Epigenetic and gene expression changes related to transgenerational carcinogenesis. Molecular Carcinogenesis, 40, 1–11.

21. Klosin, A. et al. (2017). Transgenerational transmission of environmental information in C. elegans. Science, 356(6335).

22. Lim, J.P., & Brunet, A. (2013). Bridging the transgenerational gap with epigenetic memory. Trends in Genetics, 29(3), 176-186. doi: 10.1016/j.tig.2012.12.008

23. Choi, S.-W., & Friso, S. (2010). Epigenetics: A New Bridge between Nutrition and Health Advances in Nutrition: An International Review Journal, 1(1), 8-16. doi:10.3945/an.110.1004.

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Catholic Church Ignores Pedophilia, But Bishop Warns Reiki & Energy Healing Are Satanic

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In Brief

  • The Facts:

    Catholic Bishop Alphonsus Cullinan has said he is establishing a "delivery ministry" that will attempt to rid people of the devil and warned that using reiki or other new-age healing methods could open one up to demonic influence.

  • Reflect On:

    Can these types of fear-based attempts to retain power over people serve the greater awakening to our innate power and sovereignty?

It is wisely said that, ‘you should clean up your own backyard first before you come running over to fix mine.’ Obviously, this wisdom continues to be lost on the clergy of the Catholic Church.

According to this Irish News article, Catholic Bishop Alphonsus Cullinan has said he is establishing a “delivery ministry” of people who will attempt to rid others of the devil and warned that using reiki or other new-age healing methods could open one up to the possibility of encountering malevolent spirits. He said he had received “several requests” from people to help deal with evil forces.

On the strength of what spellbinding evidence and research does the bishop rest his indictment against reiki healing treatments on? He said he was told by the brother of a reiki master that the man was “working on somebody one day when he actually says he saw a vision of Satan” and was “scared out of his wits, dropped the reiki and went back to the Church”.

Gosh. Did Bishop Cullinan even go so far as to interview the reiki master himself, to verify the authenticity of the report, and perhaps inform himself just a touch more about the philosophy and practice of reiki, before giving it such firm identification with the dark side?

Heavens, no.

 

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“This is something that has to be done in secret because you don’t let these people’s names out, and they are going to houses where people maybe have been involved in some kind of new-age thing or some kind of séance or that kind of thing, and unfortunately, they’ve opened up a door to an evil force, Satan.” Bishop Alphonsus Cullinan

Absolving Personal Responsibility

Let’s be clear on what the good bishop is saying here: he is worried about people getting influenced by Satan while engaging in ‘new-age’ healing practices.  (In fact, he misidentifies reiki as a ‘new age’ practice when in fact it was developed in the early 1900’s in Japan by Mikao Usui, who realized that healing energy can be transmitted between human beings via the hands and directed intention and visualization.) Does he say what the consequences might be if people fall deeply enough under Satan’s spell under these conditions? Will they suddenly be tempted to steal an apple from the grocery store? Say a crossword to a neighbor? He doesn’t know. And doesn’t say. And probably hasn’t even thought that far.

No, what it really looks like is that the good bishop would like to stop people who are taking personal responsibility for their own healing, and play the devil card to encourage such people to run back to the Catholic Church where members don’t actually have to take responsibility for their own actions–they can simply believe the devil made them do it. This is a scenario in which the good bishop can feel useful in an advisory capacity because he has the God-given power to absolve participants of their sins with the recitation of a few ‘Hail Mary’s.

Why Not Address In-House Pedophilia?

You would think, if indeed you believe Cullinan is being sincere, that he would not be sticking his nose into something he knows little about, and instead bring his Satan-fighting attention to the actions of his Catholic brethren who are already known to be raping and torturing children. You would think it would be of the highest order to turn his exorcising powers to work on these contemporaries of his, if for nothing else than to try to resurrect the reputation of the Catholic Church which has fallen to unprecedented depths.

But you get the feeling that his attitude falls in line with the Church on the matter of pedophilia in the church. Their inaction seems to indicate that they feel not much can be done about it. It is not a question of personal responsibility, it is a question of demonic possession. In the article, Cullinan said he “absolutely” agreed with Pope Francis’s view that child abuse is caused by Satan. Which means offenders themselves are not to ‘blame’ for their actions. The church’s propensity to take offenders of these violent crimes and simply move them away from one outraged community to continue their criminal activity in another one is a clear sign of this.

The Takeaway

This bishop certainly has gall to act concerned about potential demonic influence coming from modern energy healing practices he knows nothing about. The good news is, the hypocrisy of the Catholic Church continues to reveal itself in these feeble attempts to retain power over people, and they could serve as a catalyst for more people who still give themselves over to these institutions to take their power back.

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Consciousness

The Remarkable Brainwaves Of High-Level Meditators

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In Brief

  • The Facts:

    Expert meditators are constantly producing high range brainwave frequencies, even when they're not meditating. A normal human being rarely hits these brainwave frequencies.

  • Reflect On:

    Meditation could help people of all ages, create more peace in their lives. As it becomes a global collective practice, it will make a big impact on world peace and overall quality of life.

Listen To This Article

Measuring brainwaves while in altered states of consciousness is a fascinating way to see what happens to the brain during these states. It makes me feel that factors associated with consciousness exist separate from the brain, and that the brain is simply a receiver of this non-material input from some unidentified part of ourselves.

When it comes to meditation, scientists have been able to measure the brainwaves of high-level meditators. They found that some meditators are consistently operating in the gamma brainwave range, approximately at 40Hz. I’ve written about the brainwaves of lucid dreamers before, and those studies also show that when someone is lucid dreaming, they are also operating within the gamma brainwave range. This brainwave range is associated with a conscious state of heightened self-awareness, an even more conscious state than when one is awake.

Human beings don’t operate anywhere near these frequencies when we are in our normal wakeful state, and we operate at an even lower frequency during sleep states.

There are delta brainwaves, which are most pronounced in premature babies, then there are theta brainwaves which are characterized by light sleep, REM sleep, dreams and hallucinations.  Alpha brainwaves are an even higher frequency, which are most prominent during relaxation, contemplation and a lack of visual stimuli. These occur when you are not distracted or focused on the external world too much, and their frequency is approximately 8-12 Hz, so you can see why the jump to Gamma brainwaves for meditators is quite significant, which range from 40 – 100 Hz.

These are the fastest brainwave frequencies known to man.

It’s been more than a decade since researchers at the University of Wisconsin-Madison, found that Zen Buddhist monks show “an extraordinary synchronization of brainwaves known as gamma synchrony – a pattern increasingly associated with robust brain function and the synthesis of activity that we call the mind.”  (Scientific American)

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 Meditation has always been intertwined with “superhuman” abilities. During a visit to remote monasteries in the 1980s, Harvard Professor of Medicine Herbert Benson and his team of researchers studied monks living in the Himalayan Mountains who could, by g Tum-mo (a yoga technique), raise the temperatures of their fingers and toes by as much as 17 degrees. It is still unknown how the monks are able to generate such heat. (source). The researchers also studied advanced meditators in Sikkim, India, where they were astonished to find that these monks could lower their metabolism by 64%. (source)

It’s important to mention that meditation has also shown significant changes in the brain, with an increase in brain matter and in other ways. It’s also shown to be successful for the treatment of multiple ailments, like Irritable Bowel Syndrome. You can read more about the scientific benefits of meditation in a recent article we published, here.

In the video below, psychologist and science writer Daniel Goleman discusses his work along with his colleague and research colleague, neuroscientist, Richard Davidson. Fascinating stuff.

Expert meditators, as described below in this case, were flown in from all over the world and put in a lab.

Their brainwave, shows gamma very strong all the time as a lasting trait, no matter what they’re doing…it’s not during meditation alone, it’s just their every-day state of mind. We actually have no idea what that means experientially, science has never seen it before. We also find that in these olympic level meditators, when we asked them to do a meditation on compassion, their level of gamma jumps 700/800 percent in seconds. This has also never been seen by science. There is a state of being which is not like ordinary states, sometimes it’s called liberation, or enlightenment. There’s really no vocabulary that captures what that might be.

How To Meditate, What is Meditation?

I’ve always thought that meditation can be multiple things, but at its core involves the non-judgement of the thoughts that arise during the practice. Just let them come, and let them go as is. It also involves multiple states of meditation, as mentioned above, these experts are constantly in that “state of mind.” Many high-level meditators express how this is exactly what meditation is. That being said, sitting down, and meditating with intention and a goal in mind could also be very beneficial.

There could be multiple depths to meditation, and you don’t always have to sit cross-legged and do it a specific way. You can meditate in the shower, while you are on a walk, one person doing laundry could perhaps be in the same state of mind as another who is in a deep meditation, therefore both accomplishing the same experience, at least from a brainwave perspective that is. Just like the video explains above, they’re always in gamma range.

You want to begin by getting in a comfortable position. Take deep breaths, slow them down, and allow whatever comes into your head, to simply exit. That’s the general way start out if you’re just beginning your journey into meditation. The intention behind the meditation can be anything, including to simply experience this other state of consciousness and get closer to “source.”

The Takeaway

Imagine what would happen if 7 billion people on the planet all meditated together for world peace, would it manifest? It’s amazing what we now know about mediation, and what it can do to our biological realty. Perhaps it can do a lot to physical reality as well. These types of findings go to show that our most natural inner state is one of peace. Why else would it be the state that’s most beneficial for our body, and that allows us to operate at a higher capacity?

A Quick Important Notice:

The demand for Collective Evolution's content is bigger than ever, except ad agencies and social media keep cutting our revenues. This is making it hard for us to continue.

In order to stay truly independent, we need your help. We are not going to put up paywalls on this website, as we want to get our info out far and wide. For as little as $3 a month, you can help keep CE alive!

SUPPORT CE HERE!

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