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Flawed Medical Research May Be Ruining Your Health & Your Life (Important!)

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There is a cancer eating at the core of medical research.

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You’ve most likely heard of medical reports touting the effectiveness of a diet plan, a new drug, a supplement, or medical procedure. You may have even decided on a course of action based on these findings, only to find out later that they have been refuted by new studies.

Strikingly, the odds are that the studies that influenced your decision, and possibly the decision of your doctor, were wrong.

We are bombarded by medical research studies that don’t stand the test of time and potentially cause serious negative health outcomes.

Perhaps, because of this, you’ve become jaded about the newest health findings. I don’t wish to dissuade you from how you feel. In fact, this article will show you how untrustworthy medical research is and what you must do to protect yourself and loved ones.

The Case Against Medical Research

Medical research is fraught with incompetence, careerism, and fraud. In the April 15, 2015 edition of Lancet, the UKs leading medical journal, editor-in-chief Richard Horton stated:  “The case against science is straightforward: much of the scientific literature, perhaps half, may simply be untrue.”

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He ominously went on to say “…science has taken a turn toward darkness.”

As early as 1996, voices were being raised against the scandal of medical research. Douglas G. Altman, head of Medical Statistics Laboratory in the UK, asked the following question in the British Medical Journal (BMJ):

“What… should we think about researchers who use the wrong techniques (either willfully or in ignorance), use the right techniques wrongly, misinterpret their results, report their results selectively, cite the literature selectively, and draw unjustified conclusions?”

His answer:

“We should be appalled. Yet numerous studies of the medical literature… have shown that all of the above phenomena are common. This is surely a scandal.”

In 2005 Dr. John P.A. Ioannidis, currently a professor in disease prevention at Stanford University, published the most widely accessed article in the history of the Public Library of Science (PLoS) entitled Why Most Published Research Findings Are False. In the report, he stated:

“Therbad science 3e is increasing concern that most current published research findings are false.”

And that “…in modern research, false findings may be the majority or even the vast majority of published research claims.”

Ioannidis’ research model indicated that up to 80 percent of non-randomized research studies (the most common kind of study) are wrong, along with twenty-five percent of randomized trials (the supposed gold standard of research). Incredulously, these studies are published in top peer reviewed medical journals.

These numbers indicate that much of what our physicians prescribe to us is wrong. Our doctors use research to inform their medical decisions – decisions like what drug to prescribe, what surgery to elect, and what health strategy to adopt. They are making crucial treatment decisions for depression, Alzheimer’s, type 2 Diabetes, cancer, obesity, etc. based on bad, incomplete or hidden medical research. Remember Vioxx, Hormone Replacement Therapy, anti-arrhythmia drugs, high carbohydrate diets? The lives of hundreds of thousands of people were damaged or ended prematurely.

What’s Wrong with Medical Research?

There are serious deficiencies in medical research that have an onerous impact on our well-being.

Research Bias Ioannidis defines bias as “the combination of various design, data, analysis, and presentation factors that tend to produce research findings when they should not be produced.” Many researchers enter their study with a specific finding in mind and, not surprisingly, they find it.

Journalist David H. Freedman in Lies, Damned Lies, and Medical Science quotes Ioannidis:

“At every step in the process, there is room to distort results, a way to make a stronger claim or to select what is going to be concluded,” and there is an “intellectual conflict of interest that pressures researchers to find whatever it is that is most likely to get them funded.”

Bias can happen in numerous ways, such as how the research is designed, how the samples are selected, and how subjects are pressured, or though errors in data collection and measurement or publication bias. All of this leads to erroneous results and potentially disastrous medical advice.

Publication Bias – various industries, governments, and regulatory agencies may severely distort the truth by omission. Nearly half of all research studies never see the light of day. According to Live Science:

“Oftentimes, medical journals or pharmaceutical companies that sponsor research will report only “positive” results, leaving out the non-findings or negative findings where a new drug or procedure may have proved more harmful than helpful.”  In other words, the truth is hidden.

An example of this occurred with nearly 100,000 people dying from taking “safe” prescription anti-arrhythmic drugs in the 1980s. Or more recently, when none of the negative studies of the anti-depressant reboxitene were published.

This leaves us and our doctors in the dark about the efficacy and safety of drugs and medical procedures. We are systematically being misled!

See Dr. Ben Goldacre’s Ted Talk to learn more.

Conflicts of Interest many studies, especially drug studies, “…have the added corruptive force of financial conflict of interest.” The more embedded the financial and other interests in the outcome of a study, the more likely the findings are going to be false. Ioannidis’ own research found that conflicts of interest “are common in biomedical research and typically they are inadequately and sparsely reported.”

Conflicts of interest are not limited to financial matters:

“Many otherwise seemingly independent, university-based studies may be conducted for no other reason than to give physicians and researchers qualifications for promotion or tenure.”

Research findings can be distorted by: small sample size, poor choice of methodology, and erroneous statistical analysis, all of which are widespread in medical research.

What Can We Do to Protect Ourselves?

Given the distorted, corrupt and unreliable state of much of medical research how can we know what to do?

Short of ignoring research altogether, there are ways we can protect ourselves.

In his book WrongDavid Freedman lists some practical measures we can take to evaluate the reliability of medical research.

You can tell that a research study is probably wrong if:

  • It’s simplistic, universal and definitive. It touts a cure for cancer, obesity, and aging.
  • It’s supported by a single study, small studies or animal studies. One small study of mice proving a cure for dementia.
  • It claims to be groundbreaking. The truth about heart disease has finally been discovered.
  • It is being pushed by people or organizations that will benefit financially.
  • It’s geared toward preventing a recent trauma or occurrence from happening in the future. A quick fix to solve serious and complex problems.
  • I would add that association does not prove causation. Unless a study is a randomized control trial (RCT) it can not prove that one thing causes another, such as red meat causing heart disease.

Read Doctoring Data by Dr. Malcolm Kendrick for an in-depth study of flawed medical research.

Conclusion

There are efforts being made within science to rectify the problem with medical research. But much remains unreliable and downright wrong. We cannot afford to be fooled by flawed studies. Arm yourself with knowledge. Review the scientific reliability of a course of action. Discuss it with your physician. This can help in wading through the biased and damaging studies given the light of day in scientific journals and media. Take responsibility. Your life may depend on it.

 

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Alternative News

12,000 Doctors Urge the FDA to Put Cancer Warnings on Cheese

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In Brief

  • The Facts:

    The Physicians Committee for Responsible Medicine (PCRM) recently submitted a citizen petition with the Food and Drug Administration (FDA) to change labeling on cheese to include a cancer warning.

  • Reflect On:

    Why have our federal health regulatory agencies and big food companies marketed dairy products as safe, healthy and necessary when the science clearly suggests otherwise.

What do doctors learn about nutrition in medical school? Shockingly and unfortunately, nothing. Why? Because nutrition does not bring in profit, and treating people with nutrition hasn’t seemed to be an option at all ever since the birth of the mainstream medical industry. The sad reality is that “the medical profession is being bought by the pharmaceutical industry, not only in terms of the practice of medicine, but also in terms of teaching and research. The academic institutions of this country are allowing themselves to be the paid agents of the pharmaceutical industry. I think it’s disgraceful.” – Arnold Seymour Relman (source)

Thankfully, things are changing and changing fast. A lot of people are taking their nutritional education into their own hands, and many doctors are also educating themselves on the power of nutrition through the plethora studies and clinical evidence that’s available out there.

One of the latest examples of doctors educating themselves comes from the Physicians Committee for Responsible Medicine (PCRM), who recently submitted a citizen petition with the Food and Drug Administration (FDA) to change labeling on cheese to include a cancer warning.

Why? Because based on the research, cheese, and dairy from the animal of another is not good, but bad for us. This reality may be hard for many to believe given the fact that it’s been one of the stable food groups for so long. It’s time we start recognizing that “nutritional education” that we grow up with is a product of the big food companies and marketing, it’s not backed by any science and more people are starting to become aware of what the science is actually showing us.

The petition states:

Dairy cheese contains reproductive hormones that may increase breast cancer mortality risk. (This sentence is what they want on dairy cheese products).

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High-fat dairy products, such as cheese, are associated with an increased risk for breast cancer. Components in dairy such as insulin-like growth factor (IGF-1) and other growth hormones may be among the reasons for the increased risk for cancer.

To ensure that Americans understand the potential significant risks, and resulting long-term costs, of consuming dairy cheese products, the FDA should ensure that the notice above is prominently placed on product packaging and labeling for all dairy cheese products.

I find it interesting that they mention IGF-1 growth hormone.

A 2015 study published in Cell Metabolism is one of multiple studies that points out:

Mice and humans with Growth Hormone Receptor/IGF-1 deficiencies display major reductions in age-related diseases. Because protein restriction reduces GHR-IGF-1 activity, we examined links between protein intake and mortality. Respondents (n=6,381) aged 50–65 reporting high protein intake had a 75% increase in overall mortality and a 4-fold increase in cancer and diabetes mortality during an 18 year follow up period. These associations were either abolished or attenuated if the source of proteins was plant-based.

The study above corroborates with a lot of other research showing that animal protein skyrockets IFG-1 growth hormone, thus leading to a wide variety of diseases, in the long term, including cancer. The interesting thing is that protein from plants, as the study points out, “abolished or attenuated” these associations “if the source of proteins was plant-based.”

Fasting has been shown to reduce the risk and even reverse many age related diseases, like Parkinson’s and Alzheimer’s. It’s also been shown to regenerate stem cells and slow down the overall aging process, much of that is due to the fact that fasting drops our IGF-1 growth hormone levels.

A recent study conducted by researchers in California and France found that meat protein is associated with a very sharp increased risk of heart disease, while protein from nuts and seeds is actually beneficial for the human heart.

The study is titled “Patterns of plant and animal protein intake are strongly associated with cardiovascular mortality: The Adventist Health Study-2 cohort,” It was a joint project between researchers from Loma Linda University School of Public Health in California and AgroParisTech and the Institut National de la Recherche Agronomique in Paris, France.

It was published in the International Journal of Epidemiology. The researchers found that people who ate large amounts of meat protein, which is a daily norm for many people, represented a portion of the human population that would experience a 60 percent increase in cardiovascular disease (CVD), while people who consumed large amounts of protein from nuts and seeds actually experienced a 40 percent reduction in CVD.

Dairy “Turning on Cancer.”

Doctor Colin Campbell. author of the “China Study”  discovered that animal protein (casein) can accelerate and “turn on” cancer, while plant based protein has the opposite effect.

“What I did during the early part of my career was nothing more than what traditional science would suggest. I made the observation that diets presumably higher in animal protein were associated with liver cancer in the Philippines. When coupled with the extraordinary report from India showing that casein fed to experimental rats at the usual levels of intake dramatically promoted liver cancer, it prompted my 27-year-long study The China Project, of how this effect worked. We did dozens of experiments to see if this was true and, further, how it worked.” – Dr Colin Campbell, (China Study)

Campbell is an American biochemist who specializes in the effect of nutrition on long term health. He is Professor Emeritus of Nutritional Biochemistry at Cornell University, he has a Ph.D. in nutrition, biochemistry, and microbiology. Scholars like Campbell and their work is so important in a world of medical education and academia that almost completely ignores nutrition.

Casein is the most relevant chemical carcinogen ever identified, make no mistake about it. (source)

Campbell went beyond mere correlation and found using animal studies he conducted that casein actually “turns on” cancer. When animals were fed a diet high in casein, the cancer increased dramatically. What’s even more interesting is when they decided to do a comparison using plant protein.

What we learned along the way is that we could turn on and turn off cancer. Turn it on by increasing casein consumption, turn it off by decreasing it or replacing it with plant protein. That was a really exciting thing that we could take nutrition and turn cancer on and off, I mean that, that was pretty startling. – Campbell (source)

The Takeaway

We are the only species on the planet that consumes the dairy of another animal after weaning.  The reduction of lactase activity after infancy is a genetically programmed event. Approximately 75 % of Earths population is lactose intolerant for a reason, because it’s perfectly natural. We are not meant to drink the milk of another animal and we had to evolve the gene to digest it.  The statistics vary from race to race and country to country but overall they show an abnormal amount of individuals who qualify. In some Asian countries, 90 percent of the population is lactose intolerant.

It seems the big food companies convinced us that it’s a requirement, and that it’s healthy. They used protein and calcium (both of which are present in a number of plant sources, for example) as mass marketing tools to push dairy products on the population in order to turn a very large profit, all at the health expense of human beings.

This is one of multiple examples off mass perception manipulation.

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Consciousness

California’s First Surgeon General: Screen Every Student For Childhood Trauma

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In Brief

  • The Facts:

    California's first surgeon general Dr. Nadine Burke Harris has a dream to screen children for childhood trauma before entering schools in an attempt to help them process these experiences to avoid developmental issues.

  • Reflect On:

    Is it time we take an entirely new societal and cultural approach to the emotional challenges we collectively face? Is it time we take personal responsibility for the communities we live within?

California’s first surgeon general, Dr. Nadine Burke Harris, has an ambitious goal to screen every student for childhood trauma before entering school. Dr. Harris has dedicated her career to changing the way society views and responds to childhood trauma. This is a worthwhile effort as research shows childhood trauma affects brain development and it will build a society that is more empathetic to all and unique situations.

Why it matters: While some feel this is not the job of state to determine this, and in the wrong hands this could appear to be a pharmaceutical nightmare, it appears Dr. Harris’ specifics are going in the right direction. Reframing ‘disorders’ doctors simply don’t seem to understand is an important step in helping kids.

“One thing that tipped me off was the number of kids being sent to me by schools — principals, teachers and administrators — with ADHD […] “What I found was that many of the kids were experiencing signs of adversity, and there seemed to be a strong association between adversity and the trauma they experienced and school functioning.”

Already, Dr. Harris’ research team has found that kids who had experienced severe trauma were 32 times more likely to be diagnosed with learning and behavioural problems than kids who had not. Further pointing to the fact that many of the challenges we face in society come from challenging times and emotions that never get processed.

We live in a time where emotional intelligence and self-awareness are extremely undeveloped across the globe, and this is not being taught to enough people, especially at a young age.

The conscious takeaway: There is no doubting the fact that we need more community in our world. And while people doubt the creation of community in the wrong hands, it doesn’t mean all have nefarious intentions. Raising awareness about topics such as this whereby a leader truly feels that blanket statements like ADHD don’t really tell us anything about a child and we must look deeper, is a great thing!

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Imagine a world where education and societal culture did focus on things like emotional intelligence and helping people process their challenging experiences? We all know telling someone to just ‘buck up and let it go’ hasn’t brought us to a good space, perhaps it’s time for an entire cultural shift? This, after all, has been what we have been creating here at Collective Evolution for the last 10 years.

This story very much plays into steps 2, 3 and 4 of the CE Protocol. Awakening neutrality within people, deprogramming our limitations and then living aligned with our true and authentic self.

“When you have a whole community making real change, you can have a big and lasting change.” – Dr. Nadine Burke Harris

Looking deeper: Currently, the approach to children who are ‘problems’ in school is to get rid of them or medicate them. In fact, there are over 20 million schoolchildren who are being prescribed stimulants and psychotropic drugs according to Citizens Commission on Human Rights. Most of the public is not even aware of this. While big pharma profits huge with an unconscious approach to these challenges, society suffers greatly.

It’s truly time for something different, and all you have to ask yourself is are we capable of creating more peace within our youth and society? If yes, a new approach is needed.

20 Million Schoolchildren Have Been Prescribed Psychiatric Drugs Known to Cause Suicidal Thoughts

More Public Schools Choosing Meditation Over Detention & Teaching Mindfulness Practices

 

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Awareness

7 Ways to Prevent and Even Reverse Heart Disease with Nutrition

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In Brief

  • The Facts:

    This article was written by Sayer Ji. Founder of Greenmedinfo.com. Posted here with permission.

  • Reflect On:

    Heart disease, while still the #1 cause of mortality in the developed world, can be prevented and even reversed with nutritional interventions, according to a growing body of scientific research.

Considering that heart disease is the #1 cause of death in the developed world, anything that can prevent or reduce cardiac mortality, or slow or even reverse the cardiovascular disease process, should be of great interest to health professionals and the general public alike.

Sadly, millions are still unaware of the extensive body of biomedical literature that exists supporting the use of natural compounds for preventing and even reversing heart disease, which we have indexed on GreenMedInfo.com.

Instead, they spend billions of healthcare dollars annually on highly toxic cholesterol-lowering pharmaceuticals such as statin drugs which have known cardiotoxicity, among 300 other proven side effects, simply because their doctors told them to do so. Bad advice is the rule and not the exception here. For instance, after decades of recommending a so-called ‘low dose’ aspirin to prevent heart disease and stroke, the weight of evidence now points to it being a cause of significantly more harm than good: Doctors Reverse Decades Old Aspirin Recommendation: Deadly Risks Outweigh Benefits for Heart Disease & Stroke

So, with this in mind, let’s look at a small but significant sample of natural, food-based alternatives to these drugs through the lens of the clinical and biomedical literature itself.

Three Natural Substances that Reduce the Risk of Heart-Related Death

  • Omega-3 Fatty Acids: There is a robust body of research indicating that the risk of sudden cardiac death is reduced when consuming higher levels of omega-3 fatty acids. Going all the way back to 2002, the New England Journal of Medicine published a study titled, “Blood levels of long-chain n-3 fatty acids and the risk of sudden death,” which found: “The n-3 fatty acids found in fish are strongly associated with a reduced risk of sudden death among men without evidence of prior cardiovascular disease.” Another 2002 study, published in the journal Circulation, found that Omega-3 fatty acid supplementation reduces total mortality and sudden death in patients who have already had a heart attack.[i] For additional research, view our dataset on the topic of Omega-3 fatty acids and the reduction of cardiac mortality. It should be noted that the best-selling cholesterol drug class known as statins may actually reduce the effectiveness of omega-3 fats at protecting the heart. This has been offered as an explanation as to why newer research seems to show that consuming omega-3 fats does not lower the risk of cardiac mortality.
  • Vitamin D: Levels of this essential compound have been found to be directly associated with the risk of dying from all causes. Being in the lowest 25% percent of vitamin D levels is associated with a 26% increased rate of all-cause mortality.[ii] It has been proposed that doubling global vitamin D levels could significantly reduce mortality.[iii] Research published in the journal Clinical Endocrinology in 2009 confirmed that lower vitamin D levels are associated with increased all-cause mortality but also that the effect is even more pronounced with cardiovascular mortality.[iv] This finding was confirmed the same year in the Journal of the American Geriatric Society, [v] and again in 2010 in the American Journal of Clinical Nutrition.[vi]
  • Magnesium: In a world gone mad over taking inorganic calcium supplementation for manufactured diseases such as T-score defined “osteopenia” or “osteoporosis,”despite their well-known association with increased risk of cardiac mortality, magnesium’s role in protecting against heart disease cannot be overstressed. It is well-known that even the accelerated aging of the heart muscle experienced by those in long space flight is due to magnesium deficiency. In 2010, the Journal of Biomedical Sciences reported that cardiovascular risks are significantly lower in individuals who excrete higher levels of magnesium, indicating its protective role.[vii] Another study published in the journal Atherosclerosis in 2011 found that low serum magnesium concentrations predict cardiovascular and all-cause mortality.[viii] Remember that when you are looking to ‘supplement’ your diet with magnesium go green. Chlorophyll is green because it has a magnesium atom at its center. Kale, for example, is far better a source of complex nutrition than magnesium supplements. But, failing the culinary approach, magnesium supplements can be highly effective at attaining a therapeutic and/or cardioprotective dose.

For an additional list of compounds that may reduce cardiac mortality, including cocoa, tea, wine and yes, even cholesterol itself, view our Reduce Cardiac Mortality page.

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Four Natural Compounds Which May Unclog the Arteries

  • Pomegranate: this remarkable fruit has been found in a human clinical study to reverse the carotid artery thickness (i.e. blockage) by up to 29% within 1 year[ix] There are a broad range of mechanisms that have been identified which may be responsible for this effect, including: 1) lowering blood pressure 2) fighting infection (plaque in arteries often contains bacteria and viruses) 3) preventing cholesterol oxidation 4) reducing inflammation.[x]
  • Arginine: Preclinical and clinical research indicates that this amino acid not only prevents the progression of atherosclerosis but also reverses pathologies associated with the process. (see also: Clogged Arteries and Arginine). One of the mechanisms in which it accomplishes this feat is by increasing the production of nitric oxide which is normally depressed in blood vessels where the inner lining has been damaged (endothelium) resulting in dysfunction.
  • Garlic: Not only has garlic been found to reduce a multitude of risk factors associated with arteriosclerosis, the thickening and hardening of the arteries, but it also significantly reduces the risk of heart attack and stroke.[xi] In vitro research has confirmed that garlic inhibits arteriosclerotic plaque formation.[xii] Aged garlic extract has also been studied to inhibit the progression of coronary artery calcification in patients receiving statin therapy.[xiii] And let us not forget, garlic’s benefits are extremely broad. We have identified over 150 diseases that this remarkable culinary and medicinal herb has been confirmed to be of potential value in treating and preventing and which can be viewed here: Garlic Health Benefits.
  • B-Complex: One of the few vitamin categories that has been confirmed in human studies to not only reduce the progression of plaque buildup in the arteries but actually reverse it is B-complex. A 2009 study published in the journal Stroke found that high dose B-complex vitamin supplementation significantly reduces the progression of early-stage subclinical atherosclerosis in healthy individuals.[xiv] More remarkably, a 2005 study published in the journal Atherosclerosis found a B-vitamin formula decreased the carotid artery thickness in patients at risk for cerebral ischemia.[xv] Another possible explanation for these positive effects is the role B-vitamins have in reducing the production of homocysteine, an artery and otherwise blood vessel scarring amino acid.[xvi]

For additional research on artery unclogging substances visit our page dedicated to the topic Unclogging Arteries.

Additional Heart Unfriendly Things To Avoid

No discussion of preventing cardiac mortality would be complete without discussing things that need to be removed in order to reduce risk, such as:

  • NSAIDs: Drugs like aspirin, ibuprofen, and Tylenol, have well-known association with increased cardiac mortality. Review six studies on the topic here: NSAID Cardiotoxicity.
  • Statin Drugs: It is the height of irony that the very category of drugs promoted to millions globally as the standard of care for primary and secondary prevention of cardiovascular disease and cardiac mortality are actually cardiotoxic agents, linked to no less than 300 adverse health effects. Statin drugs have devastating health effects. Explore the research here: Statin Drug Health Effects.
  • Wheat: while this connection is rarely discussed, even by those who promote grain-free and wheat free diets, wheat has profound cardiotoxic potential, along with over 200 documented adverse health effects: Wheat Toxicity. And why wouldn’t it, when the very countries that eat the most of it have the highest rate of cardiovascular disease and heart-related deaths? For an in-depth explanation read our article: Wheat’s Cardiotoxicity: As Serious As A Heart Attack.

Finally, for additional research on the topic of heart health promoting strategies visit our Health Guide: Heart Health. Interested in healing an injured heart? Read about cardiac tissue regeneration: 6 Bodily Tissues That Can Be Regenerated Through Nutrition.


References

[i] Roberto Marchioli, Federica Barzi, Elena Bomba, Carmine Chieffo, Domenico Di Gregorio, Rocco Di Mascio, Maria Grazia Franzosi, Enrico Geraci, Giacomo Levantesi, Aldo Pietro Maggioni, Loredana Mantini, Rosa Maria Marfisi, G Mastrogiuseppe, Nicola Mininni, Gian Luigi Nicolosi, Massimo Santini, Carlo Schweiger, Luigi Tavazzi, Gianni Tognoni, Corrado Tucci, Franco Valagussa,. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico (GISSI)-Prevenzione. Circulation. 2002 Apr 23;105(16):1897-903. PMID: 11997274

[ii] Michal L Melamed, Erin D Michos, Wendy Post, Brad Astor. 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med. 2008 Aug 11;168(15):1629-37. PMID: 18695076

[iii] W B Grant. An estimate of the global reduction in mortality rates through doubling vitamin D levels. Eur J Clin Nutr. 2011 Jul 6. Epub 2011 Jul 6. PMID: 21731036

[iv] Stefan Pilz, Harald Dobnig, Giel Nijpels, Robert J Heine, Coen D A Stehouwer, Marieke B Snijder, Rob M van Dam, Jacqueline M Dekker. Vitamin D and mortality in older men and women. Clin Endocrinol (Oxf). 2009 Nov;71(5):666-72. Epub 2009 Feb 18. PMID: 19226272

[v] Adit A Ginde, Robert Scragg, Robert S Schwartz, Carlos A Camargo. Prospective study of serum 25-hydroxyvitamin D level, cardiovascular disease mortality, and all-cause mortality in older U.S. adults. J Am Geriatr Soc. 2009 Sep;57(9):1595-603. Epub 2009 Jun 22. PMID: 19549021

[vi] Karl Michaëlsson, John A Baron, Greta Snellman, Rolf Gedeborg, Liisa Byberg, Johan Sundström, Lars Berglund, Johan Arnlöv, Per Hellman, Rune Blomhoff, Alicja Wolk, Hans Garmo, Lars Holmberg, Håkan Melhus. Plasma vitamin D and mortality in older men: a community-based prospective cohort study. Am J Clin Nutr. 2010 Oct;92(4):841-8. Epub 2010 Aug 18. PMID: 20720256

[vii] Yukio Yamori, Takashi Taguchi, Hideki Mori, Mari Mori. Low cardiovascular risks in the middle aged males and females excreting greater 24-hour urinary taurine and magnesium in 41 WHO-CARDIAC study populations in the world. J Biomed Sci. 2010;17 Suppl 1:S21. Epub 2010 Aug 24. PMID: 20804596

[viii] Thorsten Reffelmann, Till Ittermann, Marcus Dörr, Henry Völzke, Markus Reinthaler, Astrid Petersmann, Stephan B Felix. Low serum magnesium concentrations predict cardiovascular and all-cause mortality. Atherosclerosis. 2011 Jun 12. Epub 2011 Jun 12. PMID: 21703623

[ix] Sayer Ji, Research: Pomegranate May Reverse Blocked Arteries

[x] GreenMedInfo.com, Pomegranate’s Health Benefits

[xi] G Siegel, A Walter, S Engel, A Walper, F Michel. [Pleiotropic effects of garlic]. Wien Med Wochenschr. 1999;149(8-10):217-24. PMID: 10483684

[xii] Günter Siegel, Frank Michel, Michael Ploch, Miguel Rodríguez, Martin Malmsten. [Inhibition of arteriosclerotic plaque development by garlic]. Wien Med Wochenschr. 2004 Nov;154(21-22):515-22. PMID: 15638070

[xiii] Matthew J Budoff, Junichiro Takasu, Ferdinand R Flores, Yutaka Niihara, Bin Lu, Benjamin H Lau, Robert T Rosen, Harunobu Amagase. Inhibiting progression of coronary calcification using Aged Garlic Extract in patients receiving statin therapy: a preliminary study. Prev Med. 2004 Nov;39(5):985-91. PMID: 15475033

[xiv] Howard N Hodis, Wendy J Mack, Laurie Dustin, Peter R Mahrer, Stanley P Azen, Robert Detrano, Jacob Selhub, Petar Alaupovic, Chao-ran Liu, Ci-hua Liu, Juliana Hwang, Alison G Wilcox, Robert H Selzer,. High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial. Stroke. 2009 Mar;40(3):730-6. Epub 2008 Dec 31. PMID: 19118243

[xv] Uwe Till, Peter Röhl, Almut Jentsch, Heiko Till, Andreas Müller, Klaus Bellstedt, Dietmar Plonné, Horst S Fink, Rüdiger Vollandt, Ulrich Sliwka, Falko H Herrmann, Henning Petermann, Reiner Riezler. Decrease of carotid intima-media thickness in patients at risk to cerebral ischemia after supplementation with folic acid, Vitamins B6 and B12. Atherosclerosis. 2005 Jul;181(1):131-5. Epub 2005 Feb 16. PMID: 15939064

[xvi] Claudio Maldonado, Chirag V Soni, Nathan D Todnem, Sathnur Pushpakumar, Dorothea Rosenberger, Srikanth Givvimani, Juan Villafane, Suresh C Tyagi. Hyperhomocysteinemia and sudden cardiac death: potential arrhythmogenic mechanisms. Curr Vasc Pharmacol. 2010 Jan;8(1):64-74. PMID: 19485933

Originally published: 2018-08-05

Aritcle updated: 2019-07-24


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