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How Big Pharma Creates Diseases For Its Medications. It’s Big Business!

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When pharmaceutical companies create a new drug, they are always looking for compounds that treat specific profitable disorders, especially if they have the potential for blockbuster status. Patent life is 20 years after the drug has been identified as viable in clinical trials – this means that no one else can make or sell the medication during that time.1

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For this reason, pharmaceutical companies prep the marketplace for years prior for a successful launch with maximum impact and profit.

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By the time a drug launches, doctors are ready to write prescriptions for that drug, and patients are primed to ask their doctors for it. Because it’s a name brand drug, the price is high, and pharma will want to keep that price point by protecting and extending their patent exclusivity as long as possible.

Pharma protects their patents in a number of ways. One option is to negotiate with generic drug manufacturers, asking them not to release their own versions for a set amount of time and money. Another way is to extend a patent by finding a new indication for it, thereby buying it another lifecycle as a brand name drug that sells at full premium price. In order to find this new indication, pharmaceutical companies have to get creative.

Pharma has found it profitable to create new illnesses to treat with successful existing drugs. An example of this phenomenon is Eli Lilly’s selective serotonin reuptake inhibitor (SSRI), Prozac. Prozac was originally launched and achieved blockbuster status with an indication for depression. The target market was doctors who specialized in central nervous system (CNS) disorders, Family Practitioners, and on the patient side, anyone who suffered from depression. As the first SSRI on the market, Prozac was hugely successful and widely prescribed for mild, moderate, and severe depression. In the USA, annual sales were $350 million in the first year alone and peaked at $2.6 billion a year.2

Doctors were also encouraged by Lilly’s pharmaceutical sales reps to prescribe Prozac for other “off label” uses. Off label uses are any symptoms that the drug is not indicated for and that haven’t been tested in clinical trials. Examples of off label use of an anti-depressant would be obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), social anxiety disorder, and panic disorder. It is interesting that prior to Prozac, there was no such “disease” as PMDD. Prozac was also recommended to be prescribed for shyness, fear of public speaking, and other non-medical conditions. And, patients were encouraged to ask for Prozac for these types of mild social phobias, making the drug very successful and profitable.

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Because Prozac impedes sexual function, it is also recommended for premature ejaculation. Now that Prozac (fluoxetine) has gone generic, it is also prescribed off label for bulimia, post-partum depression, premenstrual syndrome, fibromyalgia, body dysmorphic disorder, pathological laughter or crying, narcolepsy, agoraphobia, trichotillomania (hair pulling disorder), seasonal affective disorder (SAD), and many other ills that plague the “worried well.”

“Nothing is as lucrative as a product that someone is desperately dependent on. And, nothing is better than getting those on board who aren’t even ill.”

– John Virapen, in his whistleblower book, “Side Effects: Death Confessions of a Pharma Insider” 

Merck developed a drug treatment for benign prostatic hyperplasia (enlarged prostate, commonly referred to as BPH) named Proscar. Interestingly, Proscar was found to grow hair, and was launched as a brand new drug called Propecia for male pattern baldness which was now being positioned as a treatable “disease.” In reality, male pattern baldness is not a disease, it’s a common genetic condition. Gradual hair loss is a normal part of the aging process for many men. But, if repositioned as a disease that can be cured, it presents a huge market to be exploited for Merck.

Unfortunately, growing hair with the use of medication carries risks. In clinical trials, Propecia was found to cause sexual side effects such as decreased libido, erectile dysfunction, and ejaculation disorder. The drug launched anyway to a prepared eager-to-grow-hair target market. What the manufacturer failed to disclose in the prescribing information (PI) was that those adverse events often lingered even after patients discontinued use of the drug. At least 700 lawsuits are pending in New York State with more to come in New Jersey. The issue is that Merck knew that the adverse events would persist after patients ceased use of the drug, and they hid that information from the public.3

Pharmacia (now Pfizer) created a compound that would later be marketed as Genotropin. This drug is a human growth hormone that is targeted at “slow growing” children.4 The brand team primed the marketplace for the drug by appealing to parents of small children, essentially insinuating that being short was, in fact, a disease. Stats were gathered and a case was built that taller adults have more confidence, enjoy more advantages like promotions and raises, and generally earn more money than their shorter coworkers. What parent would want their child to miss out on those advantages? What the manufacturer failed to disclose is that there are serious side effects that come along with the use of growth hormone in a child’s developing body.

The off-label use of Genotropin was supposed to be the real cash cow. The goal of the Product Managers was to tap into the beauty market by promoting human growth hormone as an anti-aging breakthrough, attempting to relabel the entire process of aging as a disease process in need of pharmaceutical treatment. Researchers had hopes that clinical trials would demonstrate the compound stimulated the growth of muscle mass and decreased fat. Those trials never bore fruit, and Pfizer was unable to push that off label use. But it doesn’t mind promoting Genotropin to orthopedists to inject into the joints of injured athletes who are looking to recover quickly from sports injuries. Using human growth hormone may cause such side effects as pain in joints and muscles, arm and leg swelling, carpal tunnel syndrome, and gynecomastia in men (breast enlargement), and may also lead to heart disease and diabetes.5 These side effects were seen in older people rather than younger, but isn’t it older people who are more likely to take the bait of aging as a disease?

The trouble with prescribing any drug for off label use to treat a newly created disease, such as aging, is the potential for adverse events and even death. This is especially risky if that drug is prescribed by a General Practitioner who isn’t monitoring the patient for a specific disease the way a specialist would. Creating pseudo-diseases to increase profits isn’t about patient health. It’s about pharma wealth.

SOURCES

1 http://www.drugsdb.com/blog/how-long-is-a-drug-patent-good-for.html

http://archive.fortune.com/magazines/fortune/fortune_archive/2001/08/13/308077/index.htm

3 https://www.drugwatch.com/propecia/

4 http://www.genotropin.com/

5 http://www.mayoclinic.org/healthy-lifestyle/healthy-aging/in-depth/growth-hormone/art-20045735

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Attention Readers: We’ve Moved Our Journalism To The Pulse

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Take a moment and breathe. Place your hand over your chest area, near your heart. Breathe slowly into the area for about a minute, focusing on a sense of ease entering your mind and body. Click here to learn why we suggest this.

A large portion of our journalism that you’re used to seeing on our Collective Evolution platform has now moved over to The Pulse. We will be publishing most of our news articles there, while Collective Evolution focuses more on personal development.

You can follow The Pulse on Telegram, Facebook, Instagram and Twitter.  

We’ve done this for a number of reasons, mainly due to the struggles we’ve had with regards to extreme censorship at Collective Evolution. We hope you join us over at The Pulse in our quest to keep doing what we do!

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Abductions & Car Vandalism – Startling Australian UFO Report Unclassified

Gautam Peddada

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An uncovered Australian report performed by their Department of Defence. “Scientific Intelligence — General — Unidentified Flying Objects” is trending again. Those who have done extensive research on UFOs will find the Australian version of disclosure to be far more intellectually honest than the American version. Albeit it was conducted decades ago.

According to ex-US intelligence official Luis Elizondo, the Defense Department’s Inspector General is presently conducting three reviews. The inquiries vary from the Department of Defense’s handling of UFO claims to Elizondo’s alleged whistleblower retribution. The open IG cases are crucial to Australia’s report because they establish beyond a shadow of a doubt that the US Department of Defense is being dishonest and shady when it comes to the UFO subject. For decades, Australia has been a loyal friend of the United States. Within Australia’s boundaries, they share a military installation (Pine Gap). When a close defense ally’s intelligence agencies determined that the US was not being intellectually honest in its approach, perhaps it is reasonable to conclude that there is more to the tale than the 144 incidents studied since 2004 by the UAPTF.

The CIA became alarmed at the overloading of military communications during the mass sightings of 1952 and considered the possibility that the USSR may take advantage of such a situation.

Australian UFO study.

According to the summary, OSI, acting through the Robertson-Panel, encouraged the USAF to use Project Blue Book to publicly “debunk” UFOs. In a tragic twist of fate, when Australian authorities sought explanations from the US Air Force, the allegation was debunked. The authors of the study were depicted as conspiratorial and even crazy by the US Air Force. Ross Coulthart reported this, and it may be heard in a recent Project Unity interview. Courthart is an award-winning investigative journalist who is drawn to forbidden subjects. He also stated on the same podcast that a senior US Navy official identified as Nat Kobitz told him that the US had been in the midst of reverse-engineering numerous non-human craft. According to his obituary, Mr. Kobitz was a former Director of Research and Development at Naval Sea Systems Command.

Continue reading the entire article at The Pulse. 

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PGA Tour To End COVID Testing For Both Vaccinated & Non-Vaccinated Players

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In Brief

  • The Facts:

    The PGA Tour has announced that it will stop testing players every week, regardless of whether they have been vaccinated or not.

  • Reflect On:

    Are PCR tests appropriate to identify infectious people? Should people who are healthy and not sick be tested at all, anywhere?

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The picture you see above is of John Rahm, a professional golfer on the PGA tour being carted off the golf course after tournament officials told him he had COVID. He was healthy and had no symptoms, yet was forced to withdraw from the tournament. He was told in front of the camera’s, and a big scene was made out of the event. You would think something like that, especially when you are a big time sports figure, would be done behind closed doors with some privacy.

Earlier on in June a spokesperson for the PGA Tour said that more than 50 percent of players on the PGA tour have been vaccinated. Although it seems that the majority of players on the tour will be fully vaccinated judging by this statement, it does leave a fairly large minority who won’t be, and that’s something we’re seeing across the globe as COVID vaccine hesitancy remains high for multiple reasons.

We are pleased to announce, after consultation with PGA Tour medical advisors, that due to the high rate of vaccination among all constituents on the PGA Tour, as well as other positively trending factors across the country, testing for COVID-19 will no longer be required as a condition of competition beginning with the 3M Open. – PGA tour Senior VP Tyler Dennis

The tour recently announced that the testing of players every week will stop starting in July for both the vaccinated and the unvaccinated. This was an unexpected announcement given the fact that, at least it seems in some countries, vaccinated individuals will enjoy previous rights and freedoms that everyone did before the pandemic. Travelling without need to quarantine and possibly in the future not having to be tested could be a few of those privileges. Others may include attending concerts, sporting events, or perhaps even keeping their job depending on whether or not their employer deems it to be mandatory, if that’s even legally possible. We will see what happens.

Luckily for professional golfers, regardless of their vaccination status they won’t have to worry about testing positive for COVID, especially if they’re not sick. This is the appropriate move by the PGA tour, who is represented by their players and it’s a move that the players themselves may have had a say in. It’s important because PCR tests are not designed nor are they appropriate for identifying infectious people. A number of scientists have been emphasizing this since the beginning of the pandemic. More recently, a letter to the editor published in the Journal of infection explain why more than half of al “positive” PCR tests are likely to have been people who are not infectious, otherwise known as “false positives.”

This is why the Swedish Public Health agency has a notice on their website explaining how and why polymerase chain reaction (PCR) tests are not useful for determining if someone is infected with COVID or if someone can transmit it to others, and it’s better to use someone who is actually showing symptoms as a judgement call of whether or not they could be infected or free from infection.

PCR tests using a high cycle threshold are extremely sensitive. An article published in the journal Clinical Infectious Diseases found that among positive PCR samples with a cycle count over 35, only 3 percent of the samples showed viral replication. This can be interpreted as, if someone tests positive via PCR when a Ct of 35 or higher is used, the probability that said person is actually infected is less than 3%, and the probability that said result is a false positive is 97 percent. This begs the question, why has Manitoba, Canada, for example, using cycle thresholds of up to 45 to identify “positive” people?

When it comes to golf, the fact that spread occurring in an outdoor setting is highly unlikely could have been a factor, but it’s also important to mention that asymptomatic spread within one’s own household is also considerably rare. It really makes you wonder what’s going on here, doesn’t it?

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