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The Medical Medium: What May Be The Root of Modern Medical Mysteries

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In an age where millions of people are flocking to the internet and seminars to discover the latest about health because they feel doctors may not be up to date, The Medical Medium stands out as a popular go to for many.

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With a radio show on Hay House, Anthony William draws from his astounding connection to a ‘high-level’ spirit, as he calls it, and shares incredible health information to many. In his book Medical Medium: Secrets Behind Chronic and Mystery Illness and How to Finally Heal Anthony talks about the unknown reasons behind some of the many popular illnesses that plague people today. He also provides great insight into how one can treat and heal their bodies back to a healthy state – something that is rather refreshing in this day and age.

Dr. Alejandro Junger, who wrote the forward in William’s book, writes “As a man of science, I have been taught to the point of indoctrination that I must only trust what I can observe, measure, test, and reproduce.” A typical view of western medical professionals. Interestingly, Dr. Junger also has a fascination with healers. Those who appear to perform amazing feats of healing like bringing sight back or instantly healing a disease. How do these things work? Dr. Junger does what many health professionals need to do more of, question the status quo and keep an open mind.

That’s perhaps why he is so fascinated by Anthony William, because not only does he act as a healer for many, but he gets great results.

Anthony William’s website states: ‘For over 25 years, Anthony has devoted his life to helping people overcome and prevent illness—and discover the lives they were meant to live. What he does is several decades ahead of scientific discovery. His compassionate approach, which takes into account well-being on every level, not just physical health, has time and again given relief and results to those who seek him out.

Anthony’s unprecedented accuracy and success rate as the Medical Medium have earned him the trust and love of thousands worldwide, among them movie stars, rock stars, billionaires, professional athletes, best-selling authors, and countless other people from all walks of life who couldn’t find a way to heal until he provided them with insights from Spirit.’

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Written by Anthony Williams, Medical Medium: Secrets Behind Chronic and Mystery Illness and How to Finally Heal 

Epstein-Barr Virus, Chronic Fatigue Syndrome, And Fibromyalgia

The Epstein-Barr virus (EBV) has created a secret epidemic. Out of the roughly 320 million people in the U.S., over 225 million Americans have some form of EBV.

Epstein-Barr is responsible for mystery illnesses of every category: For some people, it creates fatigue and pain that go unnamed. For others, EBV symptoms prompt doctors to prescribe ineffective treatments, such as hormone replacement. And for so many people walking around with EBV, it gets misdiagnosed.

Among the reasons EBV is thriving: so little is understood about it. Medical communities are aware of only one version of EBV, but there are actually over 60 varieties. Epstein-Barr is behind several of the debilitating illnesses that stump doctors. As I said in the Introduction, it’s the mystery illness of mystery illnesses.

Doctors have no idea how the virus operates long-term and how problematic it can be. The truth is, EBV is the source of numerous health problems that are currently considered mystery illnesses, such as fibromyalgia and chronic fatigue syndrome. EBV is also the cause of some major maladies that medical communities think they understand but really don’t—including thyroid disease, vertigo, and tinnitus.

This chapter explains when the Epstein-Barr virus arose, how it’s transmitted, how it operates to create untold havoc in strategic stages no one knows about, and the steps (never revealed before) that can destroy the virus and restore health.

EPSTEIN-BARR ORIGINS AND TRANSMISSION
Though Epstein-Barr was discovered by two brilliant physicians in 1964, it had actually begun taking hold in the early 1900s—over half a century before. EBV’s initial versions—which are still with us—are relatively slow to act, and might not even create notable symptoms until late in life. Even then, they’re only mildly harmful. Many people have these non-aggressive EBV strains.

Unfortunately, EBV has evolved over the decades, and each generation of the virus has grown more challenging than the one before.

Until the publication of this book, those with EBV would typically be stuck with it for the rest of their lives. Doctors seldom recognize EBV as the root cause of the myriad of problems it creates; plus doctors have no idea how to address the Epstein-Barr virus even when it is recognized.

There are many ways to catch EBV. For example, you can get it as a baby if your mother has the virus. You can also get it through infected blood. Hospitals don’t screen for the virus, so any blood transfusion puts you at risk. You can even get it from eating out! That’s because chefs are under tremendous pressure to get dishes prepared quickly. They often end up cutting a finger or hand, slapping on a Band-Aid, and continuing to work. Their blood can get into the food…and if they happen to have EBV during a contagious phase, that can be enough to infect you.

Transmission can also happen through other bodily fluids, such as those exchanged during sex. Under some circumstances, even a kiss can be enough to transmit EBV.

Someone with the virus isn’t contagious all the time, though. It’s most likely to spread during its Stage Two. Which brings up something else that until now hasn’t been revealed: EBV goes through four stages.

EPSTEIN-BARR STAGE ONE
If you catch EBV, it goes through an initial dormant period of floating around in your bloodstream doing little more than slowly replicating itself to build its numbers—and waiting for an opportunity to launch a more direct infection.

For example, if you physically exhaust yourself for weeks and give yourself no chance to fully recover, or allow your body to become deprived of essential nutrients such as zinc or vitamin B12, or undergo a traumatic emotional experience such as a breakup or the death of a loved one, the virus will detect your stress-related hormones and choose that time to take advantage.

EBV will also often act when you’re undergoing a major hormonal change—for example, during puberty, pregnancy, or menopause. A common scenario is when a woman goes through childbirth. Afterward, she may feel various symptoms, including fatigue, aches and pains, and depression. In this case EBV isn’t exploiting your weakness, but the fact that hormones are a powerful food source for it—their abundance acts as a trigger. The hormones flooding through your body effectively does for the virus what spinach does for Popeye.

EBV is inhumanly patient. This Stage One period of fortifying itself and waiting for an ideal opportunity can take weeks, months, or even a decade or longer, depending on a variety of factors.

The virus is especially vulnerable during Stage One. However, it’s also undetectable through tests and causes no symptoms, so you normally wouldn’t know to fight it, because you wouldn’t be aware it was there.

EPSTEIN-BARR STAGE TWO
At the end of Stage One, the Epstein-Barr virus is ready to do battle with your body. That’s when EBV first makes its presence known…by turning into mononucleosis. This is the infamous mono that we all grow up hearing about as the “kissing disease.” It’s what thousands of college students contract every year when they run themselves down with all-night partying and studying.

Medical communities are unaware that every case of mononucleosis is only Stage Two of EBV.

This is the period when the virus is most contagious. It’s therefore advisable to avoid getting exposed to blood, saliva, or other bodily fluids from someone who has mono…or to avoid exposing anyone to your fluids if you have mono.

During this Stage Two, your body’s immune system goes to war with the virus. It sends identifier cells to “tag” virus cells, i.e., place a hormone on them that marks them as invaders. It then sends soldier cells to seek out and kill the tagged virus cells. This is the power of your immune system coming to your defense.

How severely this battle rages will vary from person to person, because everyone is different, and it will also depend on what EBV strain or variety a person has. You can have mono for just a week or two with a mild scratchy throat and tiredness, in which case you aren’t likely to realize what’s really happening, so you most likely won’t visit a doctor for a blood test.

Then again, you can get hit hard with fatigue, sore throat, fever, headaches, rashes, and more that hang on for several months. If this happens, the chances are you’ll go see a doctor who’ll test your blood, and the Epstein-Barr virus will show up as a form of mono…most of the time.

It’s during this stage that EBV seeks a long-term home by making a run for one or more of your major organs—typically your liver and/or spleen. EBV loves being in these organs because mercury, dioxins, and other toxins are likely to accumulate there. The virus thrives on these poisons.

One other secret about EBV is that it has a best friend, a bacterium called Streptococcus. In such cases your body is dealing with not only a virus, but also bacteria that further confuse the immune system and produce their own array of symptoms. This is Epstein-Barr’s number one cofactor.

During EBV’s Stage Two, Streptococcus can travel up to create strep throat and/or infest the sinuses, nose, or mouth. It can also travel down to create infections in the urinary tract, vagina, kidneys, or bladder . . . eventually causing cystitis.

EPSTEIN-BARR STAGE THREE
Once the virus settles into your liver, spleen, and/or other organs, it nests there.

From this point on, when a doctor tests for Epstein-Barr, she or he will find antibodies and take these to indicate a past infection, when EBV was in its mono phase. The doctor will not find the EBV presently active in the bloodstream. The confusion here is one of the biggest blunders in medical history—this is how this virus has slipped through the cracks. Unless you have already followed the measures outlined in this book to kill the EBV, the virus is, in fact, still alive and causing new symptoms…and it’s eluding the tests. That’s because it’s living in the liver, spleen, or other organs, and the test to detect this has not yet been invented.

With the virus hiding undetected in your organs, your body assumes it’s won the war and the invader has been destroyed. Your immune system returns to its normal state, your mononucleosis ends, and your doctor tells you that you’re healthy.

Unfortunately, the Epstein-Barr virus has barely begun its voyage through your body.

If you have a typical variety, EBV could lie dormant in your organs for years—possibly for decades—without your knowing it. If you have an especially aggressive variety, though, EBV may create serious problems even while it’s nesting.

For example, the virus may burrow deep into your liver and spleen, causing those organs to become inflamed and enlarged. And once again, keep in mind that your doctor does not know to connect the dots between past EBV and its present activity in the organs.

The virus also creates three types of poison:

EBV excretes toxic waste matter, or viral byproduct. This becomes increasingly significant as the virus grows more cells, and its expanding army keeps eating and excreting poisonous byproduct. This waste matter is often identified as spirochetes, which can trigger false positives on tests such as Lyme titers (screening tests for Lyme disease) and lead to a false diagnosis of Lyme.
When a cell of the virus dies—which happens often, as the cells have a six-week life cycle—the corpse that is left behind is itself toxic and so further poisons your body. As with viral byproduct, this problem becomes more severe as EBV’s army grows, creating fatigue.

The poisons EBV creates through these two processes have the ability to generate a neurotoxin—i.e., a poison that disrupts nerve function and confuses your immune system. It will secrete this special toxin at strategic periods during Stage Three, and continuously during Stage Four, to prevent your immune system from zeroing in on the virus and attacking it.
The issues that may result from an aggressive variety of EBV nesting in your organs include:

Your liver performing so sluggishly that it does a poor job of flushing toxins out of your system.
Hepatitis C. (EBV is actually the primary cause of hepatitis C.)

Your liver’s sluggish performance leading to the lowering of your stomach’s hydrochloric acid and your intestinal tract starting to become toxic. This in turn can result in some food not being fully digested and instead putrefying in your intestinal tract, resulting in bloating and/or constipation.

Your developing sensitivities to foods that never caused you problems before. This happens when the virus consumes a food it likes, such as cheese, and transforms it into something your body doesn’t recognize.

The virus bides its time until it senses stress-related hormones indicating you’re in an especially vulnerable state—say, as a result of burning the candle at both ends, enduring a severe emotional blow, or suffering a physical jolt such as being in a car accident—or when it senses you’re undergoing hormonal upheaval, such as during pregnancy or menopause.

When the virus is nearly ready to spring, it begins excreting its neurotoxin. This adds to the burden on your system already created by EBV’s byproduct and virus corpses. All this poison in your system finally triggers your immune system—and also thoroughly confuses it, because it has no idea where the toxins are coming from.

Lupus
The immune system response I’ve just described triggers the mysterious symptoms that doctors can diagnose as lupus. Medical communities have no understanding that lupus is just the body reacting to Epstein-Barr’s byproducts and neurotoxins. It’s the body having an allergic reaction to these neurotoxins, which then elevates the inflammatory markers that doctors search for to identify and diagnose lupus. In truth, lupus is just a viral infection of Epstein-Barr.

Hypothyroidism and Other Thyroid Disorders
While your immune system is in disarray, EBV takes advantage of the chaos by leaving the organs it’s been nesting in and making a run for a different major organ or gland—which this time is your thyroid!

Medical communities aren’t yet aware that EBV is the actual cause of most thyroid disorders and diseases—especially Hashimoto’s, but also Graves’, thyroid cancer, and other thyroid ills. (Thyroid disease is also sometimes caused by radiation; but in over 95 percent of cases, the culprit is Epstein-Barr.) Medical research has not yet uncovered the true causes of thyroid disorders, and it’s still decades away from discovering that EBV is the virus that causes them. If a doctor gives you a Hashimoto’s diagnosis, it really means that she or he doesn’t know what’s wrong. The claim is that your body is attacking your thyroid—a view that arises from misinformation. In truth, it’s the EBV—not your body—attacking the thyroid.

Once in your thyroid, EBV begins drilling into its tissues. The virus cells literally twist and spin like drills to burrow deep into the thyroid, killing thyroid cells and scarring the organ as they go, creating hidden hypothyroidism in millions of women, from mild cases to the more extreme. Your immune system notices this and tries to intervene, causing inflammation; but between EBV’s neurotoxin, viral byproduct, and poisonous corpses confusing things, and with EBV hiding in your thyroid, your immune system can’t tag the virus for complete destruction.

While the above may sound unnerving, don’t let it rattle you; your thyroid has the ability to rejuvenate and heal itself when it’s given what it needs. And never underestimate the power of your immune system, which by the end of this chapter will become activated just by you learning the truth.

As a fallback option, your immune system tries to wall off the virus with calcium, creating nodules in your thyroid. However, this doesn’t hurt EBV. First, most of its cells evade this attack and remain free. Second, a virus cell that your immune system successfully walls off typically remains alive and turns its calcium prison into a comfortable home, where it feeds on your thyroid, draining it of energy. The virus cell might even eventually transform its prison into a living growth, called a cyst, that creates further strain on your thyroid.

Meanwhile, these attacks against EBV can hurt you if you aren’t eating enough calcium-rich foods. That’s because if your immune system can’t get the calcium to wall off the virus from your bloodstream, it’ll extract what it needs from your bones…which can lead to osteoporosis.

Simultaneously, the hundreds of virus cells that aren’t imprisoned in nodules can weaken your thyroid, making it less effective at producing the hormones your body needs to function. This lack of adequate thyroid hormones, coupled with EBV’s toxins, can in turn lead to weight gain, fatigue, mental fogginess, impaired memory, depression, hair loss, insomnia, brittle nails, muscle weakness, and/or dozens of other symptoms.

Some especially rare, aggressive varieties of EBV go even further. They create cancer in the thyroid. The rate of thyroid cancer in the U.S. has been rising rapidly. Medical communities don’t know that the cause is an increase in rare, aggressive forms of EBV.

The Epstein-Barr virus invades your thyroid for a strategic reason—it’s seeking to confuse and place stress on your endocrine system. The strain on your adrenal glands produces more adrenaline, which is a favored food of EBV that makes it stronger and better able to go after its ultimate target: your nervous system.

EPSTEIN-BARR STAGE FOUR
The ultimate goal of the Epstein-Barr virus is to leave your thyroid and inflame your central nervous system.

Your immune system normally wouldn’t allow this to happen. But if EBV has successfully worn you down in Stage Three by entering your thyroid, and if on top of that you abruptly get clobbered with some physical or severe emotional injury, the virus will take advantage of your vulnerability and start to cause a multitude of strange symptoms that range from heart palpitations to generalized aches and pains to nerve pain.

A common scenario is being in an accident, getting surgery, or suffering some other physical damage, and then feeling awful for much longer than would be expected from the injury alone. A typical reaction is to “feel like a truck hit me.”

Blood tests, X-rays, and MRIs will reveal nothing wrong, so doctors won’t be aware of the virus inflaming the nerves. Stage Four Epstein-Barr is therefore a major source of mystery illnesses—that is, problems that cause doctors massive confusion.

What’s actually happening is that your injured nerves trigger an “alarm” hormone to notify your body that the nerves are exposed and need repair. In Stage Four, EBV detects that hormone and rushes over to latch onto those damaged nerves.

A nerve is similar to a string of yarn with little root hairs hanging off it. When the nerve is injured, the root hairs pop off the sides of the nerve sheath. EBV looks for those openings and grabs onto them. If it succeeds, it can keep the area inflamed for years. As a result, you can have a relatively small injury that remains flared up and causes you continual pain.

The issues that result from this viral inflammation can include muscle pain, joint pain, painful tender points, back pain, tingling and/or numbness in the hands and feet, migraines, ongoing fatigue, dizziness, insomnia, unrestful sleep, and night sweats. Patients with these issues are sometimes diagnosed as having fibromyalgia, chronic fatigue syndrome, or rheumatoid arthritis, all of which are collections of symptoms that medical communities admit they don’t understand and for which they have no cure. In such cases the patients are given inappropriate treatments that don’t begin to address the real culprit—because these mystery illnesses are really Stage Four Epstein-Barr.

One of the greatest missteps of all time is mistaking women’s Epstein-Barr symptoms for perimenopause and menopause. Symptoms such as hot flashes, night sweats, heart palpitations, dizziness, depression, hair loss, and anxiety were and are frequently misinterpreted as hormonal change—which is what launched the disastrous HRT movement. (To learn more, see Chapter 15, “Premenstrual Syndrome and Menopause.”)

Let’s take a closer look at the chronic illnesses that have puzzled doctors for decades and are the result of Stage Four Epstein-Barr.

Chronic Fatigue Syndrome
There’s a long history of womankind facing denial that there’s a physical cause of their suffering. Like those with fibromyalgia (see below), people with chronic fatigue syndrome (CFS)—also known by names such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), chronic fatigue immune dysfunction syndrome (CFIDS), and systemic exertion intolerance disease (SEID)—often hear that they are liars, lazy, delusional, and/or crazy. It’s an illness that affects women in disproportionately large numbers.

And chronic fatigue syndrome is on the rise.

It’s becoming common for young women in college to return home mid-semester with the condition, unable to do anything but lie in bed. Contracting CFS as a woman in your late teens or early 20s can be particularly devastating as you watch friends move on with relationships and jobs, meanwhile feeling stuck and unable to live up to your potential.

Women who get CFS in their 30s, 40s, or 50s have their own obstacles: while you’re old enough at this point to have an established life and support network, you also have established responsibilities. You’re likely trying to be everything to everybody, taking care of more than you can handle, and so you feel the pressure to act normal when CFS hits.

Compounding the isolation for both age groups are the feelings of guilt, fear, and shame that accompany their misdiagnoses. I’m sure that if you have CFS, you’ve been in the depths of physical suffering and had someone say, “But you look perfectly healthy.” It is so disheartening to feel unwell and hear from practitioners, friends, or family that there’s nothing wrong with you.

Chronic fatigue syndrome is real. It’s the Epstein-Barr virus.

As we’ve seen, those with CFS have an elevated viral load of EBV, which systematically afflicts the body by creating a neurotoxin that inflames the central nervous system. This can eventually weaken the adrenals and digestive system, and create the feeling that you have a low battery.

Fibromyalgia
We’ve had over six decades of medical denial that fibromyalgia is a legitimate problem. Now, medical communities are finally accepting it as an actual condition.

The best explanation doctors are given by the establishment, though, is that fibromyalgia is overactive nerves. What this really translates to is…no one has a clue. It’s not the doctors’ fault. There’s no magic book they receive that tells them what will help their fibromyalgia patients or what is genuinely causing their pain.

The medical system is still years from discovering the illness’s true root—because it’s viral, and it takes place at a nerve level that medical tools currently can’t detect.

Those suffering from fibromyalgia are under a very real and debilitating attack. It’s the Epstein-Barr virus that is causing this disorder, inflaming both the central nervous system and nerves throughout the body, which creates ongoing pain, sensitivity to touch, severe fatigue, and a host of other issues.

Tinnitus
Tinnitus, or ringing in the ear, is usually caused by EBV getting into the inner ear’s nerve channel, called the labyrinth. The ringing is the result of the virus inflaming and vibrating the labyrinth and the vestibulocochlear nerve.

Vertigo and Meniere’s Disease
Vertigo and Meniere’s disease are often attributed by doctors to calcium crystals, or stones, becoming disrupted in the inner ear. However, most chronic cases are actually caused by EBV’s neurotoxin inflaming the vagus nerve.

Other Symptoms
Anxiety, dizziness, chest tightness, chest pain, esophageal spasms, and asthma can also be caused by EBV inflaming the vagus nerve.

Insomnia, and tingling and numbness in hands and feet, can be caused by phrenic nerves becoming perpetually inflamed by EBV.

And heart palpitations can result from buildup of EBV’s poisonous virus corpses and byproduct in the heart’s mitral valve.

If you have EBV, or suspect you do, you may find the virus in Stage Four beyond frustrating. Take comfort. If you take the right steps—which medical communities don’t know about yet, but which are covered at the end of this chapter—you can recover, rebuild your immune system, return to a normal state again, and regain control of your life.

1cec5f_032e6c289fbb49b7b4daaa34b0d12e9aTYPES OF EPSTEIN-BARR
As I’ve noted earlier, there are over 60 varieties of the Epstein-Barr virus. That number is so large because EBV has existed for well over 100 years. It’s had generations of people to move through, mutating and elevating its various hybrids and strains in that time. The strains can be organized into six groups of escalating severity, with roughly ten types per group.

EBV Group 1 is the oldest and mildest. These versions of the virus typically take years, even decades, to transition from one stage to another. Their effects might not be noticeable until you’re in your 70s or 80s, and then result in little more than back pain. They might even remain in your organs and never reach Stage Three or Stage Four.

EBV Group 2 moves from stage to stage a bit quicker than Group 1; you might notice symptoms in your 50s or 60s. These varieties may partially linger in the thyroid and send only some of their virus cells out to inflame nerves, resulting in relatively mild nerve inflammation. The only variety of EBV that medical communities are aware of is in this group.

EBV Group 3 will transition between stages faster than Group 2, so its symptoms might be noticeable around age 40. Also, these viruses fully complete Stage Four—that is, they entirely leave the thyroid to latch onto nerves. Viruses in this group can cause a variety of ills, including joint pain, fatigue, heart palpitations, tinnitus, and vertigo.

EBV Group 4 will create noticeable problems as early as age 30. Its aggressive actions on nerves can result in symptoms associated with fibromyalgia, chronic fatigue syndrome, brain fog, confusion, anxiety, moodiness, and everything caused by Groups 1 to 3. This group can also create symptoms of post traumatic stress disorder, even if a person never underwent any trauma beyond getting inflamed by the virus.

EBV Group 5 will create noticeable issues as early as age 20. This is an especially nasty form of the virus because it strikes just when a young person is setting out to start an independent life. It can create all the problems of Group 4, and it feeds off negative emotions such as fear and worry. Doctors who can’t find anything wrong, and perceive these patients as young and healthy, often declare “it’s all in your head” and send them to psychologists to convince them what’s actually happening in their bodies isn’t real. Unless, that is, a patient happens upon a doctor who’s up on the Lyme disease trend, in which case the patient will probably walk away with a Lyme misdiagnosis.

The worst type, however, is EBV Group 6, which can strike hard even in young children. In addition to everything Group 5 does, Group 6 can create symptoms so severe that they’re misdiagnosed as leukemia, viral meningitis, lupus, and more. Plus it suppresses the immune system, which can lead to a wide variety of symptoms including rashes, weakness in the limbs, and severe nerve pain.

HEALING FROM THE EPSTEIN-BARR VIRUS
Because it’s very easy to catch and hard to detect, and can cause a number of mysterious symptoms, you might understandably find the Epstein-Barr virus overwhelming and its effects disheartening.

The good news is that if you carefully and patiently follow the steps detailed in this section, and in Part IV of the book, you can heal. You can recover your immune system, free yourself of EBV, rejuvenate your body, gain full control over your health, and move on with your life.

How long the process takes varies for each individual and depends on myriad factors. Some people conquer the virus in as little as three months. However, a more typical period is a full year. And there are some people who need 18 months or more to destroy EBV.

Healing Foods
Certain fruits and vegetables can help your body rid itself of EBV and heal from its effects. The following are the best ones to incorporate into your diet (listed in rough order of importance). Try to eat at least three of these foods per day—the more the better—rotating your consumption so that in a given week or two, you get all of these foods into your system.

  • Wild blueberries: help restore the central nervous system and flush EBV neurotoxins out of the liver.
  • Celery: strengthens hydrochloric acid in the gut and provides mineral salts to the central nervous system.
  • Sprouts: high in zinc and selenium to strengthen the immune system against EBV.
  • Asparagus: cleanses the liver and spleen; strengthens the pancreas.
  • Spinach: creates an alkaline environment in the body and provides highly absorbable micronutrients to the nervous system.
  • Cilantro: removes heavy metals such as mercury and lead, which are favored foods of EBV.
  • Parsley: removes high levels of copper and aluminum, which feed EBV.
  • Coconut oil: antiviral and acts as an anti-inflammatory.
  • Garlic: antiviral and antibacterial that defends against EBV.
  • Ginger: helps with nutrient assimilation and relieves spasms associated with EBV.
  • Raspberries: rich in antioxidants to remove free radicals from the organs and bloodstream.
  • Lettuce: stimulates peristaltic action in the intestinal tract and helps cleanse EBV from the liver.
  • Papayas: restore the central nervous system; strengthen and rebuild hydrochloric acid in the gut.
  • Apricots: immune system rebuilders that also strengthen the blood.
  • Pomegranates: help detox and cleanse the blood as well as the lymphatic system.
  • Grapefruit: rich source of bioflavonoids and calcium to support the immune system and flush toxins out of the body.
  • Kale: high in specific alkaloids that protect against viruses such as EBV.
  • Sweet potatoes: help cleanse and detox the liver from EBV byproducts and toxins.
  • Cucumbers: strengthen the adrenals and kidneys and flush neurotoxins out of the bloodstream.
  • Fennel: contains strong antiviral compounds to fight off EBV.

Healing Herbs and Supplements
The following herbs and supplements (listed in rough order of importance) can further strengthen your immune system and aid your body in healing from the virus’s effects:

  • Cat’s claw: herb that reduces EBV and cofactors such as strep A and strep B.
  • Silver hydrosol: lowers EBV viral load.
  • Zinc: strengthens the immune system and protects the thyroid from EBV inflammation.
  • Vitamin B12 (as methylcobalamin and/or adenosylcobalamin): strengthens the central nervous system.
  • Licorice root: lowers EBV production and strengthens the adrenals and kidneys.
  • Lemon balm: antiviral and antibacterial. Kills EBV cells and strengthens the immune system.
  • 5-MTHF (5-methyltetrahydrofolate): helps strengthen the endocrine system and central nervous system.
  • Selenium: strengthens and protects the central nervous system.
  • Red marine algae: powerful antiviral that removes heavy metals such as mercury and reduces viral load.
  • L-lysine: lowers EBV load and acts as a central nervous system anti-inflammatory.
  • Spirulina (preferably from Hawaii): rebuilds the central nervous system and eliminates heavy metals.
  • Ester-C: strengthens the immune system and flushes EBV toxins from the liver.
  • Nettle leaf: provides vital micronutrients to the brain, blood, and central nervous system.
  • Monolaurin: antiviral; breaks down EBV load and reduces cofactors.
  • Elderberry: antiviral; strengthens the immune system.
  • Red clover: cleanses the liver, lymphatic system, and spleen of neurotoxins from EBV.
  • Star anise: antiviral; helps destroy EBV in the liver and thyroid.
  • Curcumin: component of turmeric that helps strengthen the endocrine system and central nervous system.

KNOWLEDGE IS POWER
The first step of the healing process is to know the cause of your suffering is Epstein-Barr—and to realize it’s not your fault.

Your EBV-related health problems aren’t the result of anything you did wrong or any moral failing. You didn’t make this happen, and you’re in no way to blame. You did not manifest this; you did not attract this. You’re a vibrant, wonderful human being and you have every God-given right to heal. You deserve to heal.

Much of EBV’s effectiveness stems from hiding in the shadows so that neither you nor your body’s immune system can sense its presence. This not only allows it to commit its mayhem unchecked, it leads to negative emotions such as guilt, fear, and helplessness.

Now things are different for you. If you have EBV, you now have a mind-body understanding of what’s causing your health problems. From this alone, your immune system will strengthen and the virus will naturally weaken. So when it comes to fighting EBV, in a very real sense, knowledge is power.


Check out Anthony William’s entire book Medical Medium: Secrets Behind Chronic and Mystery Illness and How to Finally Heal

The views expressed in this article intend to highlight alternative studies and induce conversation. This article is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment, and should never be relied upon for specific medical advice.

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Awareness

Scientists Break Down How Aging Is “Plastic” & We Can Manipulate It To Slow Down Aging

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In Brief

  • The Facts:

    Slowing down the ageing process is not about looks, it's about health, and feeling good. Scientists have discovered multiple healthy ways to regenerate our immune systems and repair our DNA, and caloric restriction/fasting is one of them.

  • Reflect On:

    Why are we told to eat three meals a day? Why are our national food guides more of a guide towards bad health rather than health? Why have many people stopped caring about health? To change the world, we have to change ourselves in multiple ways.

Can we reverse age regression, or slow it down? Given our research into Black Budget programs, it’s clear what we know in the mainstream scientific world differs greatly from the world of secrecy. We recently conducted an interview with a neuroscientist from the University of Arizona who also makes a clear distinction between mainstream science and Black Budget science.

From a mainstream scientific standpoint, it is reversible. At least in human cells and in mice. 

This is why it’s always interesting to ponder just how advanced the world might be. The U.S. air strike against Libya in 1986 used the F-111 fighter aircraft, for instance, but not the F-117A Nighthawk. The latter was still classified at the time, and keeping it secret was more important than using it for this mission. Then there’s the National Reconnaissance Office, which was founded in 1960 but remained completely secret for 30 years. What type of technology were/are they using? Does the NSA have computers that are far more advanced than ours? Can we teleport? Can we travel faster than the speed of light? Is there a secret space program? Can humans be cloned?

While these questions might conflict with many people’s belief systems, they represent valid concerns. Another question worth asking is, can we reverse age regression? We have no idea what military technology is capable of, or how far beyond us it has progressed. Considering the advancements in technology in the past century alone within the mainstream scientific/technical world, these things are hardly beyond our grasp.

But let’s take a look at what we do know. We are, after all, living in a world where science fiction is becoming a reality.

Aging Is Reversible

Today, scientists are actually able to tweak genes that turn adult cells back into embryonic-like ones. For example, it wasn’t long ago that researchers at the Salk Institute for Biological Studies reversed the aging of human and mouse cells, in vitro. The study was published in the journal Cell

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According to Juan Carlos Izpisua Belmonte, the study’s senior author and an expert in gene expression at Salk, “aging is something plastic that we can manipulate.” In living mice, they activated what are known as “Yamanaka factors,” which rejuvenated muscles that were damaged, as well as the pancreas in a middle-aged mouse. This extended the lifespan of the mouse, who also had a genetic mutation for Hutchinson-Gilford progeria syndrome, which causes rapid aging in children.

The researchers believe that this study suggests it’s not just possible to slow the aging process, but actually reverse it.

“I fully agree with the conclusions. This work indicated that epigenetic shift is parr responsible for aging, and reprogramming can correct these epigenetic errors. This will be the basis for future exciting developments.”

– Manuel Serrano from the Spanish National Cancer Research Center In Madrid

Epigenetics is the study of changes in organisms caused by gene expression, and gene expression can change due to a myriad of factors.

But, as Scientific American points out“The study also showed how fine the line can be between benefit and harm. When the researchers treated mice continually, some developed tumors and died within a week. When the scientists cut the treatment to two days out of seven, however, the mice benefited significantly.” 

The lead author also told Scientific American that they “currently think the brain’s hypothalamus—known as the seat of control for hormones, body temperature, mood, hunger and circadian rhythms—may also act as a regulator of aging.”

According to the Telegraph, with the success of these animals studies, scientists predict human trials to commence within 10 years.

Caloric Restriction and Fasting 

Did you know that, in all animal model studies, caloric restriction reverses signs of aging, slowing it down, and reverses age-related diseases? Research has shown that it reduces what’s called the PKA enzyme, which has been linked to aging, tumour progression, and cancer.

According to a review of fasting literature conducted in 2003“Calorie restriction (CR) extends lifespan and retards age-related chronic diseases in a variety of species, including rats, mice, fish, flies, worms, and yeast. The mechanism or mechanisms through which this occurs are unclear.”

Fasting and caloric restriction have also shown to have a tremendous effect on the brain. As an article from John Hopkins Magazine reveals:

Dietary changes have long been known to have an effect on the brain. Children who suffer from epileptic seizures have fewer of them when placed on caloric restriction or fasts. It is believed that fasting helps kick-start protective measures that help counteract the overexcited signals that epileptic brains often exhibit. (Some children with epilepsy have also benefited from a specific high-fat, low-carbohydrate diet.) Normal brains, when overfed, can experience another kind of uncontrolled excitation, impairing the brain’s function.

A plate, fork and knife

Fasting has also been shown to regenerate the immune system and our organs. With regards to the brain, fasting challenges it, and your brain responds to that challenge by adapting stress response pathways that help your brain cope with stress and disease risk. The same changes that occur in the brain during fasting mimic the changes that occur with regular exercise — both increase the production of protein in the brain (neurotrophic factors), which in turn promotes the growth of neurons, the connection between neurons, and the strength of synapses. This is why it’s been found to completely reverse age-related neurodegenerative diseases.

Here is an excellent  TEDx talk given by Mark Mattson, the current Chief of the Laboratory of Neuroscience at the National Institute on Aging. He is also a professor of Neuroscience at Johns Hopkins University, and one of the foremost researchers of the cellular and molecular mechanisms underlying multiple neurodegenerative disorders, like Parkinson’s and Alzheimer’s disease.

We’ve published many articles on fasting, and to find out more information on how to do it, different strategies, and more science, you can start here. Below are a select few related articles:

Neuroscientist Shows What Fasting Does To Your Brain & Why Big Pharma Won’t Study It 

The Complete Guide To Fasting & Reversing Type 2 Diabetes: A Special Inter Interview With Dr. Jason Fung

Why Researchers Are Seeking FDA Approval For Fasting & Caloric Restriction For Cancer Treatment 

Scientists Discover That Fasting Triggers Stem Cell Regeneration & Fights Cancer

Reversing the Age of White Blood Cells

Elizabeth Parris, the CEO of Bioviva USA Inc, has become the very first human being to successfully, from a biological standpoint, reverse the age of her white blood cells, thanks to her own company’s experimental therapies. Bioviva utilizes intramural and extramural peer-reviewed research to create therapies for age-related diseases (Parkinson’s, Alzheimer’s, cancer, heart-disease), and now, they have reversed 20 years of ‘telomere shortening’ in a human for the first time.

Telomeres are short segments of DNA that cap the ends of every chromosome and act as a protective feature against wear and tear, which occurs naturally as the human body ages. As we age, these telomeres become shorter and shorter as our cells continue to divide more and more. Eventually, they become too short to protect the chromosome, which is what causes our cells to malfunction and age-related diseases to start setting in.

We published a story about this early last year, and you can read more about it here:

First Human Being Has Their DNA Manipulated To Make White Blood Cells 20 Years Younger

So, as you can see, even within the mainstream scientific world, we’re not too far off from reversing aging, or slowing it down to prevent age-related diseases. This research represents just the tip of the iceberg, and at our current rate of acceleration with regards to scientific and technological advancement, who knows where we will be in 20 years?

Would age reversal be “playing God?” It’s impossible to say. Perhaps “God” meant us to discover our own intelligence and ability and use these findings for good. Perhaps manipulating our own genes is part of our natural process of human evolution and development. This, however, is a completely separate topic, worthy of another article.

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Awareness

22 Out Of 25 Popular Burger Chains Just Failed Their Antibiotic Use Report

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In Brief

  • The Facts:

    A recent study was done examining how well top fast food chains actually implemented their antibiotic use policies in their beef. 22 of 25 failed including McDonald's, Sonic, Burger King and In-N-Out.

  • Reflect On:

    Do you still eat fast food? If so, why do you find yourself doing so? What healthier choices can be made instead? If we want to see a healthier world, population and animal kingdom, we have to choose what we support more wisely.

The modern-day food industry seems to pay no attention to health. Thankfully, global consciousness is shifting in several ways including how we live as humans, view our health, our economy, education, politics, and the environment. You could say that humanity is going through one MASSIVE change.

Today, billions of animals in the United States alone are raised, tortured, and slaughtered for human consumption. This reckless production and consumption, in turn, has created enormous environmental and health problems that continue to accelerate. That being said, awareness on this issue (food) in particular, has come along way. We are seeing changes in the food guide, a shift towards plant-based diets, and more corporations catering to new choices people are making around food and health. This is a good thing!

One common trend helping to create change is the continues ‘bad press’ unhealthy players in the food industry are getting.

The latest news to come out regarding food quality within fast food comes from a report recently released by six major consumer and environmental groups. They graded America’s 25 largest burger chains and their use of antibiotics in their beef supply.

22 popular fast food restaurants completely failed, including giants like McDonald’s, Burger King, Sonic and In-N-Out.  The evaluation looked at each chain’s antibiotic use policies and whether these policies were truly implemented in their product. They also examined how transparent the chains were with their antibiotic use.

The Problem With Antibiotic Use

Antibiotics given to farm animals can lead to antibiotic-resistant bacteria, among other things. This is actually one of the top threats to global public health, which is exemplified by the fact that each year, more than 2 million Americans alone suffer from these infections.

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In September 1999, Albrecht and Schutte published “Homeopathy Versus Antibiotics in Metaphylaxis of Infectious Diseases: A Clinical Study in Pig Fattening and Its Significance to Consumers” in Alternative Therapies. The study compared outcomes for four randomly assigned groups of pigs that were given placebo, homeopathic treatment, a standard blend of antibiotics and other conventional drugs in a routine low prophylactic dose, or conventional drugs in a high therapeutic dose.

There were 1440 pigs involved in the study, which took place at an intensive livestock farm in Germany. The primary outcome measured was the incidence of respiratory disease, a common problem for pigs on such farms.

The results were astounding.

Homeopathic treatment was far superior to prophylactic doses of antibiotics in preventing respiratory disease. The prophylactic antibiotic treatment made it only 11 percent less likely (than placebo) that the pigs would become sick. But homeopathic remedies made it 40 percent less likely. When the antibiotics were raised to therapeutic levels, meaning a level that is only given when people or an animal was sick, it became 70 percent less likely that the pigs would become diseased.

The significance of this is that homeopathic treatment on animals would already be better than routine antibiotic treatment. When an animal is actually sick, the farmer would then have the choice to increase homeopathic or use a legitimately high-level dose of antibiotics. This, significantly less cost and significantly fewer antibiotics in meat.

The List

The Takeaway

Simple, avoid fast food. There are many out there who seem to believe that people will always consume this food, but we fail to recognize that it’s not just our choice. The “food” these corporations offer is highly addictive to people, and that’s done on purpose.

If we can connect with caring about our health, quality of life and well-being of animals and the planet, these are places you must steer away from. In general, eating meat does not support the health and wellbeing of us nor animals, but this is a choice we each make.

Recommended Articles

A Native American Perspective On Veganism

Plant-Based Protein VS. Protein From Meat: Which One Is Better For You? 

Doctor Explains How Humans Have A “Strict” Vegan Physiology

Vegan Activist James Aspey Beautifully Shows How To Consciously Inform People

9 Things That Happen When You Stop Eating Meat

Internal Medicine Physician Shares What Happens To Your Body When You Stop Eating Meat

Animals – Why Do We Love One But Eat The Other? 

The Heart Disease Rates of Meat-Eaters Versus Vegetarians & Vegans

Were Those Who Roamed The Earth Before US Nearly All Vegetarian?

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Epigenetic Memories Are Passed Down 14 Successive Generations, Game-Changing Research Reveals

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In Brief

  • The Facts:

    It's amazing how much information can be passed on to our offspring. Scientist have discovered that our DNA has memories, and these can also be passed down. We are talking about thoughts, feelings, emotions and perceptions.

  • Reflect On:

    Biological changes are shaped by our environment, as well as our thoughts, feelings, emotions and reaction to that environment. Our DNA can be changed with belief, the placebo is a great example. Thoughts feelings and emotions are huge in biology.

This article was written by the Greenmedinfo research group, from Greenmedinfo.com. Posted here with permission.

Until recently, it was believed that our genes dictate our destiny. That we are slated for the diseases that will ultimately beset us based upon the pre-wired indecipherable code written in stone in our genetic material. The burgeoning field of epigenetics, however, is overturning these tenets, and ushering in a school of thought where nurture, not nature, is seen to be the predominant influence when it comes to genetic expression and our freedom from or affliction by chronic disease.

Epigenetics: The Demise of Biological Determinism

Epigenetics, or the study of the physiological mechanisms that silence or activate genes, encompasses processes which alter gene function without changing the sequence of nucleotide base pairs in our DNA. Translated literally to mean “in addition to changes in genetic sequence,” epigenetics includes processes such as methylation, acetylation, phosphorylation, sumolyation, and ubiquitylation which can be transmitted to daughter cells upon cell division (1). Methylation, for example, is the attachment of simple methyl group tags to DNA molecules, which can repress transcription of a gene when it occurs in the region of a gene promoter. This simple methyl group, or a carbon bound to three hydrogen molecules, effectively turns the gene off.

Post-translational modifications of histone proteins is another epigenetic process. Histones help to package and condense the DNA double helix into the cell nucleus in a complex called chromatin, which can be modified by enzymes, acetyl groups, and forms of RNA called small interfering RNAs and microRNAs (1). These chemical modifications of chromatin influence its three-dimensional structure, which in turn governs its accessibility for DNA transcription and dictates whether genes are expressed or not.

We inherit one allele, or variant, of each gene from our mother and the other from our father. If the result of epigenetic processes is imprinting, a phenomenon where one of the two alleles of a gene pair is turned off, this can generate a deleterious health outcome if the expressed allele is defective or increases our susceptibility to infections or toxicants (1). Studies link cancers of nearly all types, neurobehavioral and cognitive dysfunction, respiratory illnessesautoimmune disorders, reproductive anomalies, and cardiovascular disease to epigenetic mechanisms (1). For example, the cardiac antiarrhythmic drug procainamide and the antihypertensive agent hydralazine can cause lupus in some people by causing aberrant patterns of DNA methylation and disrupting signalling pathways (1).

Genes Load the Gun, Environment Pulls the Trigger

Pharmaceuticals, however, are not the only agents that can induce epigenetic disturbances. Whether you were born via vaginal birth or Cesarean section, breastfed or bottle-fed, raised with a pet in the house, or infected with certain childhood illnesses all influence your epigenetic expression. Whether you are sedentary, pray, smoke, mediate, do yoga, have an extensive network of social support or are alienated from your community—all of your lifestyle choices play into your risk for disease operating through mechanisms of epigenetics.

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In fact, the Centers for Disease Control (CDC) states that genetics account for only 10% of disease, with the remaining 90% owing to environmental variables (2). An article published in the Public Library of Science One (PLoS One) entitled “Genetic factors are not the major causes of chronic diseases” echoes these claims, citing that chronic disease is only 16.4% genetic, and 84.6% environmental (3). These concepts make sense in light of research on the exposome, the cumulative measure of all the environmental insults an individual incurs during their life course that determines susceptibility to disease (4)

In delineating the totality of exposures to which an individual is subjected over their lifetime, the exposome can be subdivided into three overlapping and intertwined domains. One segment of the exposome called the internal environment is comprised of processes innate to the body which impinge on the cellular milieu. This encompasses hormones and other cellular messengers, oxidative stress, inflammation, lipid peroxidation, bodily morphology, the gut microbiotaaging and biochemical stress (5).

Another portion of the exposome, the specific external environment, consists of exposures including pathogens, radiation, chemical contaminants and pollutants, and medical interventions, as well as dietary, lifestyle, and occupational elements (5). At an even broader sociocultural and ecological level is the segment of the exposome called the general external environment, which may circumscribe factors such as psychological stress, socioeconomic status, geopolitical variables, educational attainment, urban or rural residence, and climate (5).

Transgenerational Inheritance of Epigenetic Change: Endocrine Disruptors Trigger Infertility in Future Generations

Scientists formerly speculated that epigenetic changes disappear with each new generation during gametogenesis, the formation of sperm and ovum, and after fertilization. However, this theory was first challenged by research published in the journal Science which demonstrated that transient exposure of pregnant rats to the insecticide methoxychlor, an estrogenic compound, or the fungicide vinclozolin, an antiandrogenic compound, resulted in increased incidence of male infertility and decreased sperm production and viability in 90% of the males of four subsequent generations that were tracked (1).

Most notably, these reproductive effects were associated with derangements in DNA methylation patterns in the germ line, suggesting that epigenetic changes are passed on to future generations. The authors concluded, “The ability of an environmental factor (for example, endocrine disruptor) to reprogram the germ line and to promote a transgenerational disease state has significant implications for evolutionary biology and disease etiology” (6, p. 1466). This may suggest that the endocrine-disrupting, fragrance-laden personal care products and commercial cleaning supplies to which we are all exposed may trigger fertility problems in multiple future generations.

Transgenerational Inheritance of Traumatic Episodes: Parental Experience Shapes Traits of Offspring

In addition, traumatic experiences may be transmitted to future generations via epigenetics as a way to inform progeny about salient information needed for their survival (7). In one study, researchers wafted the cherry-like chemical acetophenone into the chambers of mice while administering electric shocks, conditioning the mice to fear the scent (7). This reaction was passed onto two successive generations, which shuddered significantly more in the presence of acetophenone despite never having encountered it compared to descendants of mice that had not received this conditioning (7).

The study suggests that certain characteristics of the parental sensory environment experienced before conception can remodel the sensory nervous system and neuroanatomy in subsequently conceived generations (7). Alterations in brain structures that process olfactory stimuli were observed, as well as enhanced representation of the receptor that perceives the odor compared to control mice and their progeny (7). These changes were conveyed by epigenetic mechanisms, as illustrated by evidence that the acetophenone-sensing genes in fearful mice were hypomethylated, which may have enhanced expression of odorant-receptor genes during development leading to acetophenone sensitivity (7).

The Human Experience of Famine and Tragedy Spans Generations

The mouse study, which illustrates how germ cells (egg and sperm) exhibit dynamic plasticity and adaptability in response to environmental signals, is mirrored by human studies. For instance, exposures to certain stressors such as starvation during the gestational period are associated with poor health outcomes for offspring. Women who undergo famine before conception of her offspring have been demonstrated to give birth to children with lower self-reported mental health and quality of life, for example (8).

Studies similarly highlight that, “Maternal famine exposure around the time of conception has been related to prevalence of major affective disorders, antisocial personality disorders, schizophrenia, decreased intracranial volume, and congenital abnormalities of the central nervous system” (8). Gestational exposure to the Dutch Famine of the mid-twentieth century is also associated with lower perceived health (9), as well as enhanced incidence of cardiovascular disease, hypertension, and obesity in offspring (8). Maternal undernourishment during pregnancy leads to neonatal adiposity, which is a predictor of future obesity (10), in the grandchildren (11).

The impact of epigenetics is also exemplified by research on the intergenerational effects of trauma, which illuminates that descendants of people who survived the Holocaust exhibit abnormal stresshormone profiles, and low cortisol production in particular (12). Because of their impaired cortisol response and altered stress reactivity, children of Holocaust survivors are often at enhanced risk for post-traumatic stress disorder (PTSD), anxiety, and depression (13).

Intrauterine exposure to maternal stress in the form of intimate partner violence during pregnancy can also lead to changes in the methylation status of the glucocorticoid receptor (GR) of their adolescent offspring (14). These studies suggest that an individual’s experience of trauma can predispose their descendants to mental illness, behavioral problems, and psychological abnormalities due to “transgenerational epigenetic programming of genes operating in the hypothalamic-pituitary-adrenal axis,” a complex set of interactions among endocrine glands which determine stress response and resilience (14).

Body Cells Pass Genetic Information Directly Into Sperm Cells

Not only that, but studies are illuminating that genetic information can be transferred through the germ line cells of a species in real time. These paradigm-shifting findings overturn conventional logic which postulates that genetic change occurs over the protracted time scale of hundreds of thousands or even millions of years. In a relatively recent study, exosomes were found to be the medium through which information was transferred from somatic cells to gametes.

This experiment entailed xenotransplantation, a process where living cells from one species are grafted into a recipient of another species. Specifically, human melanoma tumor cells genetically engineered to express genes for a fluorescent tracer enzyme called EGFP-encoding plasmid were transplanted into mice. The experimenters found that information-containing molecules containing the EGFP tracer were released into the animals’ blood (15). Exosomes, or “specialized membranous nano-sized vesicles derived from endocytic compartments that are released by many cell types” were found among the EGFP trackable molecules (16, p. 447).

Exosomes, which are synthesized by all plant and animal cells, contain distinct protein repertoires and are created when inward budding occurs from the membrane of multivesicular bodies (MVBs), a type of organelle that serves as a membrane-bound sorting compartment within eukaryotic cells (16). Exosomes contain microRNA (miRNA) and small RNA, types of non-coding RNA involved in regulating gene expression (16). In this study, exosomes delivered RNAs to mature sperm cells (spermatozoa) and remained stored there (15).

The researchers highlight that this kind of RNA can behave as a “transgenerational determinant of inheritable epigenetic variations and that spermatozoal RNA can carry and deliver information that cause phenotypic variations in the progeny” (15). In other words, the RNA carried to sperm cells by exosomes can preside over gene expression in a way that changes the observable traits and disease risk of the offspring as well as its morphology, development, and physiology.

This study was the first to elucidate RNA-mediated transfer of information from somatic to germ cells, which fundamentally overturns what is known as the Weisman barrier, a principle which states that the movement of hereditary information from genes to body cells is unidirectional, and that the information transmitted by egg and sperm to future generations remains independent of somatic cells and parental experience (15).

Further, this may bear implications for cancer risk, as exosomes contain vast amounts of genetic information which can be source of lateral gene transfer (17) and are abundantly liberated from tumor cells (18). This can be reconciled with the fact that exosome-resembling vesicles have been observed in various mammals (15), including humans, in close proximity to sperm in anatomical structures such as the epididymis as well as in seminal fluid (19). These exosomes may thereafter be propagated to future generations with fertilization and augment cancer risk in the offspring (20).

The researchers concluded that sperm cells can act as the final repositories of somatic cell-derived information, which suggests that epigenetic insults to our body cells can be relayed to future generations. This notion is confirmatory of the evolutionary theory of “soft inheritance” proposed by French naturalist Jean-Baptiste Lamarck, whereby characteristics acquired over the life of an organism are transmitted to offspring, a concept which modern genetics previously rejected before the epigenetics arrived on the scene. In this way, the sperm are able to spontaneously assimilate exogenous DNA and RNA molecules, behaving both as vector of their native genome and of extrachromosomal foreign genetic material which is “then delivered to oocytes at fertilization with the ensuing generation of phenotypically modified animals” (15).

Epigenetic Changes Endure Longer Than Ever Predicted

In a recent study, nematode worms were manipulated to harbor a transgene for a fluorescent protein, which made the worms glow under ultraviolet light when the gene was activated (21). When the worms were incubated under the ambient temperature of 20° Celsius (68° Fahrenheit), negligible glowing was observed, indicating low activity of the transgene (21). However, transferring the worms to a warmer climate of 25°C (77° F) stimulated expression of the gene, as the worms glowed brightly (21).

In addition, this temperature-induced alteration in gene expression was found to persist for at least 14 generations, representing the preservation of epigenetic memories of environmental change across an unprecedented number of generations (21). In other words, the worms transmitted memories of past environmental conditions to their descendants, through the vehicle of epigenetic change, as a way to prepare their offspring for prevailing environmental conditions and ensure their survivability.

Future Directions: Where Do We Go From Here?

Taken cumulatively, the aforementioned research challenges traditional Mendelian laws of genetics, which postulate that genetic inheritance occurs exclusively through sexual reproduction and that traits are passed to offspring through the chromosomes contained in germ line cells, and never through somatic (bodily) cells. Effectively, this proves the existence of non-Mendelian transgenerational inheritance, where traits separate from chromosomal genes are transmitted to progeny, resulting in persistent phenotypes that endure across generations (22).

This research imparts new meaning to the principle of seven generation stewardship taught by Native Americans, which mandates that we consider the welfare of seven generations to come in each of our decisions. Not only should we embody this approach in practices of environmental sustainability, but we would be wise to consider how the conditions to which we subject our bodies—the pollution and toxicants which permeate the landscape and pervade our bodies, the nutrient-devoid soil that engenders micronutrient-poor food, the disruptions to our circadian rhythm due to the ubiquity of electronic devices, our divorce from nature and the demise of our tribal affiliations—may translate into ill health effects and diminished quality of life for a previously unfathomed number of subsequent generations.

Hazards of modern agriculture, the industrial revolution, and contemporary living are the “known or suspected drivers behind epigenetic processes…including heavy metals, pesticides, diesel exhaust, tobacco smoke, polycyclic aromatic hydrocarbons, hormones, radioactivity, viruses, bacteria, and basic nutrients” (1, p. A160). Serendipitously, however, many inputs such as exercise, mindfulness, and bioactive components in fruits and vegetables such as sulforaphane in cruciferous vegetables, resveratrol from red grapes, genistein from soy, diallyl sulphide from garlic, curcumin from turmeric, betaine from beets, and green tea catechin can favorably modify epigenetic phenomena “either by directly inhibiting enzymes that catalyze DNA methylation or histone modifications, or by altering the availability of substrates necessary for those enzymatic reactions” (23, p. 8).

This quintessentially underscores that the air we breathe, the food we eat, the thoughts we allow, the toxins to which we are exposed, and the experiences we undergo may persevere in our descendants and remain in our progeny long after we are gone. We must be cognizant of the effects of our actions, as they elicit a ripple effect through the proverbial sands of time.

You can join the Greenmedinfo newsletter here for updates and more information about the world of health

References

1. Weinhold, B. (2006). Epigenetics: The Science of Change. Environmental Health Perspectives, 114(3), A160-A167.

2. Centers for Disease Control and Prevention. (2014). Exposome and Exposomics. Retrieved from https://www.cdc.gov/niosh/topics/exposome/

3. Rappaport, S.M. (2016). Genetic factors are not the major causes of chronic diseases. PLoS One, 11(4), e0154387.

4. Vrijheid, M. (2014). The exposome: a new paradigm to study the impact of environment on health. Thorax, 69(9), 876-878. doi: 10.1136/thoraxjnl-2013-204949.

5. Wild, C.P. (2012). The exposome: from concept to utility. International Journal of Epidemiology, 41, 24–32. doi:10.1093/ije/dyr236

6. Anway, M.D. et al. (2005). Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science, 308(5727), 1466-1469.

7. Dias, B.G., & Ressler, K.J. (2014). Parental olfactory experience influences behavior and neural structure in subsequent generations. Nature Neuroscience, 17(1), 89-98.

8. Stein, A.D. et al. (2009). Maternal exposure to the Dutch Famine before conception and during pregnancy: quality of life and depressive symptoms in adult offspring. Epidemiology, 20(6), doi:  10.1097/EDE.0b013e3181b5f227.

9. Roseboom, T.J. et al. (2003). Perceived health of adults after prenatal exposure to the Dutch famine. Paediatrics Perinatal Epidemiology, 17, 391–397.

10. Badon, S.E. et al. (2014). Gestational Weight Gain and Neonatal Adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Study-North American Region. Obesity (Silver Spring), 22(7), 1731–1738.

11. Veenendaal, M.V. et al. (2013). Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine. BJOG, 120(5), 548-53. doi: 10.1111/1471-0528.

12. Yehuda, R., & Bierer, L.M. (2008). Transgenerational transmission of cortisol and PTSD risk. Progress in Brain Research, 167, 121-135.

13. Aviad-Wilcheck, Y. et al. (2013). The effects of the survival characteristics of parent Holocaust survivors on offsprings’ anxiety and depression symptoms. The Israel Journal of Psychiatry and Related Sciences, 50(3), 210-216.

14. Radke, K.M. et al. (2011). Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor. Translational Psychiatry, 1, e21. doi: 10.1038/tp.2011.21.

15. Cossetti, C. et al. (2014). Soma-to-Germline Transmission of RNA in Mice Xenografted with Human Tumour Cells: Possible Transport by Exosomes. PLoS One, https://doi.org/10.1371/journal.pone.0101629.

16. Zomer, A. et al. (2010). Exosomes: Fit to deliver small RNA. Communicative and Integrative Biology, 3(5), 447–450.

17. Balaj, L. et al. (2011) Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences. Natural Communications, 2, 180.

18. Azmi, A.S., Bao, B., & Sarkar, F.H. (2013). Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. Cancer Metastasis Review, 32, 623-643

19. Poliakov, A. et al. (2009). Structural heterogeneity and protein composition of exosomes-like vesicles (prostasomes) in human semen. Prostate, 69, 159-167.

20. Cheng, R.Y. et al. (2004) Epigenetic and gene expression changes related to transgenerational carcinogenesis. Molecular Carcinogenesis, 40, 1–11.

21. Klosin, A. et al. (2017). Transgenerational transmission of environmental information in C. elegans. Science, 356(6335).

22. Lim, J.P., & Brunet, A. (2013). Bridging the transgenerational gap with epigenetic memory. Trends in Genetics, 29(3), 176-186. doi: 10.1016/j.tig.2012.12.008

23. Choi, S.-W., & Friso, S. (2010). Epigenetics: A New Bridge between Nutrition and Health Advances in Nutrition: An International Review Journal, 1(1), 8-16. doi:10.3945/an.110.1004.

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