Connect with us

Discover

Scientist Discovers A Virus That Could Cure Alzhiemer’s, Parkinson’s, And More

Published

on

There is currently no cure for Alzheimer’s disease, and while available treatments can temporarily slow the worsening of dementia symptoms and improve quality of life for those suffering from it, they cannot stop the disease from progressing altogether.

advertisement - learn more

But Israeli scientist Beka Solomon may have made a major breakthrough for Alzheimer’s and other brain diseases. The professor, from Tel Aviv University, made an incredible discovery one day when testing a new class of agents against Alzheimer’s disease. The main component is a humble virus scientists refer to as M13, and if successful, it may even mark the beginning of the end of many neurodegenerative diseases.

Of the various forms of viruses, there is one kind that solely infects bacteria. Called bacteriophages, or simply phages, these microbes are more than three billion years old, and reside everywhere on the planet.

M13 is a phage that infects just one type of bacteria, Escherichia coli, or E. coli, found in large quantities within mammalian intestines. The purpose of this phage is to pass on their genes, and in order to do this, they have developed tools to allow them to infiltrate, take over, and kill their bacteria hosts.

It all surfaced in 2004. Solomon was conducting an experiment on a group of mice that had been genetically engineered to develop Alzheimer’s disease plaques in their brains in hopes of seeing whether human-made antibodies delivered through the animals’ nasal passages would penetrate the blood-brain barrier and dissolve the amyloid-beta plaques in their brains. She decided to attach them to M13 phages in an attempt to dissolve more of the plaques and therefore improve the symptoms in the mice.

“The mice showed very nice recovery of their cognitive function,” Solomon explained. In fact, upon examining the brains of the mice, she and her team found that the plaques had been largely dissolved. After running the experiment for a year, Solomon discovered that the phage-treated mice had 80 percent fewer plaques than untreated ones. But how?

advertisement - learn more

While Solomon was unsure, she knew her findings were important, so she decided to patent M13’s therapeutic properties for the University of Tel Aviv. Eventually, in 2007, Solomon’s son, Jonathan Solomon, and fellow Harvard student Hampus Hillerstrom, with $150,000 in seed money contributed by family members, began a new venture, NeuroPhage Pharmaceuticals. Their first order of business was to explore M13’s therapeutic properties.

Researchers at NeuroPhage then discovered something completely unanticipated: the M13 virus was able to dissolve other amyloid aggregates — the tau tangles found in Alzheimer’s and also the amyloid plaques linked to other diseases like alpha-synuclein (Parkinson’s), huntingtin (Huntington’s disease) and superoxide dismutase (amyotrophic lateral sclerosis). The phage proved powerful against the amyloids in prion diseases (a class that includes Creutzfeldt-Jakob disease) as well.

NeuroPhage’s chief scientific officer, Richard Fisher, and his colleagues demonstrated this first by way of test tubes and then in a series of animal experiments. They determined that the M13 virus seemed to possess the properties of a “pan therapy,” which is a universal elixir of the kind the chemist Chris Dobson had once speculated could combat alpha-synuclein for Parkinson’s, as well as amyloids caused by many protein-misfolding diseases at once.

They soon found that M13 phage’s special abilities involved a set of proteins displayed on the tip of the virus, named GP3.

“We tested the different variants for examples of phages with or without tip proteins, and we found that every time we messed around with the tip proteins, it lowered the phage’s ability to attach to amyloids,” explained Rajaraman Krishnan, an Indian postdoctoral student working in an MIT laboratory whom Fisher had recruited to investigate the M13 puzzle.

Fisher found the whole ordeal entirely serendipitous. He said that, by “sheer luck, M13’s keys not only unlock E. coli; they also work on clumps of misfolded proteins.” Fisher explained that the odds of this happening by chance are miniscule. “Viruses have exquisite specificity in their molecular mechanisms, because they’re competing with each other…and you need to have everything right, and the two locks need to work exactly the way they are designed. And this one way of getting into bacteria also works for binding to the amyloid plaques that cause many chronic diseases of our day.”

The team’s next order of business was to see if they could capture the phage’s ability to bust amyloids in a more patient friendly medicine, so they created a new antibody that had the GP3 protein on its surface in order to dissolve amyloid plaques. By 2013, NeuroPhage had tested the new compound, called NPT088, in test tubes and in animals, including nonhuman primates, and found that it performed incredibly well.

So, the big question remains: Will it work in humans?

Although NPT088 is made up of large molecules, it is still fairly poor at penetrating the blood-brain barrier. However, because the medicine persists in the body for several weeks, Fisher believes that, over time, enough can infiltrate the brain to effectively remove plaques.

The hope is to administer the antibody to patients once or twice per month via intravenous infusion for as long as needed.

And if it works, it will undoubtedly change the world. “A single compound that effectively treats Alzheimer’s and Parkinson’s could be a twenty billion-dollar-a-year blockbuster drug,” noted Solomon.

Free Docu-series - Supplements Revealed

Over the past year, Revealed Films has been filming researchers, medical professionals, scientists, athletes, executives, moms, advocates, and many more to clear the air on all things supplements. The global viewing event for Supplements Revealed is finally here and we want you to see it - February 18-28.

Click To Register Free

Advertisement
advertisement - learn more

Alternative News

If You Could Power Your Entire Home With 60 Minutes Of Cycling, Would You Do It?

Published

on

In Brief

  • The Facts:

    Mechanical energy, converted into kinetic energy can provide the energy that we use on a regular basis to power our homes and electronic devices.

  • Reflect On:

    Rather than focusing on the current problems in our world it is great to change gears and have a look at all of the solutions that are popping up all over the world.

Imagine if your morning workout could power your home for the entire day, all the way until your next morning workout. Well, you may not have to imagine, as this technology exists now. Manoj Bhargava has invented a new exercise bike that can power some homes for 24 hours after use for only sixty minutes per day.

This invention was a part of a new initiative to bring electricity to places that undergo frequent power outages or may only have access to power for a few hours during the day. In our modern age, going without electricity can really separate a person from the rest of the world. Bhargava’s mission is to bridge the gap for those who suffer from poverty and make it easier for them to access the same information as the rest of the world, potentially giving them more opportunities in life.

The Free Electric

The above heading is also the name of this awesome and innovative bike serving as a solution to a pretty significant issue in the underdeveloped nations of the world.

According to Bhargava, the Free Electric is meant to lead to “better health, more leisure time, better access to education and opportunities for entrepreneurship.” He also feels that it could, “literally change the world.”

Power to change the world? Bold statement, but if this is able to be implemented worldwide, I would absolutely have to agree with him. This technology not only has the capacity to assist those in poverty, but can also be used by the rest of the world as well as more and more people around the world who are aiming to reduce their usee of fossil fuels. I have a feeling that Millennials (such as myself) and younger generations would be all over this if its made available! Not only is it a great way to get your cardio in, but it provides FREE electricity that produces no other pollution.

advertisement - learn more

As mentioned in the video, it is also a great solution in the face of natural, or even man made disasters because this type of electricity would not rely on that generated and sold by power companies. Perhaps even one day a way to stock up and store this energy will be possible — then, the opportunities here will be much more plentiful and could be a huge factor in reducing the amount of pollution our current methods of energy production are creating.

The Future Is Friendly

As much as there is sometimes destruction all around us, there is also innovation and ingenuity. Human beings have tremendous potential. Even though there are many problems that we as a society are facing, solutions are popping up and fast, and in most cases they already exist. Finding solutions doesn’t seem to be the problem, so ask yourself, what is?  It’s so great to see ideas such as these being conceptualized and then created and put into use so efficiently, it shows how our species is capable of stopping and potentially reversing some of the destruction that we have caused over the years.

This is absolutely a double win! We are constantly bombarded with news stories and articles that are telling us to be more active, stop sitting so much, and now with the Free Electric, we will have to be active before we can relax and enjoy the use of our precious technology.

Free Docu-series - Supplements Revealed

Over the past year, Revealed Films has been filming researchers, medical professionals, scientists, athletes, executives, moms, advocates, and many more to clear the air on all things supplements. The global viewing event for Supplements Revealed is finally here and we want you to see it - February 18-28.

Click To Register Free

Continue Reading

Discover

Physicists ‘Grow’ A Man Made Diamond From Nuclear Waste That’s Able To Generate Electricity

Published

on

In Brief

  • The Facts:

    Scientists have developed a technology that can convert leftover radioactive materials into diamond batteries to power a wide range of electronics.

  • Reflect On:

    Could this be the solution to use op all the radioactive materials on the planet and shut down nuclear power plants worldwide?

Currently there is more than 2 billion tons of nuclear waste across the globe. This nuclear waste is a hazardous threat to the environment if not disposed of correctly. Scientists have recently begun attempting to transform nuclear waste into batteries that could last for thousands of years. If they are successful with this conversion project it would be a double win, less nuclear waste contaminating our environment, and a way to reuse energy that was generated to give power to whatever requires it.

Diamond batteries that use the energy from leftover radioactive materials have been developed and tested by researchers at the University of Bristol. They are now hoping to be able to recycle the waste leftover from decommissioned nuclear power plants in the UK. According to the University, “New technology has been developed that uses nuclear waste to generate electricity in a nuclear-powered battery….A team of physicists and chemists from the University of Bristol have grown a man-made diamond that, when placed in a radioactive field, is able to generate a small electrical current.” (source)

How Does This Work?

According to The Independent,

Carbon-14 isotopes extracted from graphite blocks produced by the plant are infused with wafer-thin diamonds to create the batteries, which researchers say are capable of providing power on a “near-infinite basis”.

Potential applications range from powering hearing aids and pacemakers, to extending the range of spacecraft to distances much further than are currently possible.

“Eventually, a highly powerful version of a diamond battery could power a mobile phone,” James Barker, from the University of Bristol’s Faculty of Engineering, told The Independent.

advertisement - learn more

“Primarily though, they are best for devices requiring long lifetime, low power and where it is difficult to replace energy sources.”

In order to make these diamond batteries safe for medical and consumer use they are encased in a non-radioactive diamond layer, which will absorb any radiation given off by the C14 source.

According to the University,

Unlike the majority of electricity-generation technologies, which use energy to move a magnet through a coil of wire to generate a current, the man-made diamond is able to produce a charge simply by being placed in close proximity to a radioactive source.

Tom Scott, Professor in Materials in the University’s Interface Analysis Centre and a member of the Cabot Institute, said: “There are no moving parts involved, no emissions generated and no maintenance required, just direct electricity generation.  By encapsulating radioactive material inside diamonds, we turn a long-term problem of nuclear waste into a nuclear-powered battery and a long-term supply of clean energy.”

Could This Be The Solution We’ve Been Searching For?

“The ultimate aim is to have a factory based at one of the former power stations in the South West that takes Carbon-14 isotopes directly from the graphite blocks for use in diamond batteries. This would significantly reduce the radioactivity of the remaining material, making it easier and safer to manage,” said Professor Tom Scott, director of the South West Nuclear Hub.

“With the majority of the UK’s nuclear power plants set to go offline in the next 10-15 years this presents a huge opportunity to recycle a large amount of material to generate power for so many great uses.”

Time will tell how effective this method that scientists have come up with will be able to be implemented worldwide, but if it is, just imagine the implications of what this technology could represent.

Is It Time To Move Away From Nuclear Energy?

You’d think since the Fukushima disaster there would be a worldwide agreement for countries to stop generating power from nuclear reactors and to safely shut down these plants. Nuclear disasters have devastating effects on our planet and all of it’s inhabitants, recovery from such accidents can take tens of thousands of years to lose their hazardous radioactivity. Take the Chernobyl disaster that occurred in 1986 and is now contained under a metal shell, this site will likely remain radioactive for up to 20,000 years.

Instead of waiting for these disasters to occur, shouldn’t we be safely dismantling these sites before any more devastating disasters occur? Thankfully many countries are vowing to shut down their nuclear power plants and we can only hope that the rest of the world will follow suit.

The Future Is Here

There are so many amazing technologies that have the capacity to revolutionize the way we use energy on this planet. Of course many of those are hidden from us, especially if they cannot be in some way profited from, and unfortunately as it seems, if they don’t exploit the environment and our resources in some way.

As innovative ideas abound and technology continues to rapidly develop, we have to assume that safer and more innovative means of producing electricity will be uncovered. Hopefully these technologies will also have the capacity to undo some of the damage that we have done to our planet.

At the end of the day, using nuclear energy is not needed anymore, and in reality nuclear waste should not even exist at this point in our development as a collective.

Free Docu-series - Supplements Revealed

Over the past year, Revealed Films has been filming researchers, medical professionals, scientists, athletes, executives, moms, advocates, and many more to clear the air on all things supplements. The global viewing event for Supplements Revealed is finally here and we want you to see it - February 18-28.

Click To Register Free

Continue Reading

Alternative News

Galaxies Millions of Light Years Apart Seem To Be Connected By Invisible “Large Scale Structures”

Published

on

In Brief

  • The Facts:

    A study published in The Astrophysical Journal in October found that hundreds of galaxies were rotating in sync with the motions of galaxies that were tens of millions of light years away. This suggests that an invisible force somehow connects them.

  • Reflect On:

    How much of what we know, and what we think we know, is false? Are our minds open to accepting new concepts of reality that don't fit within the framework of accepted knowledge?

“We are all connected” — a statement that may evoke an eye-roll from someone you express this to. This is common when it comes to such topics, or any topic that dives into the ‘spooky’ world of quantum physics, which seems to be directly intertwined with philosophy and metaphysics in various ways. These subjects are going to really conflict with the belief systems of many, and that’s ok.

“There is nothing new to be discovered in physics now. All that remains is more and more precise measurement.” This statement was made by Lord Kelvin — a famous Scottish mathematician and physicist who contributed to many branches of physics — in 1900, and shattered only five years later when Einstein published his paper on special relativity. The new theories proposed by Einstein challenged the current framework of understanding, forcing the scientific community to open up to an alternative view of the true nature of our reality. This serves as a great example of how things that are originally taken as truth can suddenly turn out to be fiction.

This type of thing is happening quite often today, and with most of us trying to put food on the table and pay our bills, we don’t really have time to keep up with all that’s being discovered.

When it comes to the connection between all living systems, there are a number of examples one could use from many different fields of study. We see connection in all different forms, including all the way down to smallest bits of matter, the physical ‘stuff’ that our world is made up of. In quantum entanglement, for example, particles remain connected so that if you separate them, regardless of distance, whatever actions are performed on one of them affect the other. This has been seen with photons, for example.

This strange connection is not only seen at the smallest levels of the physical world, but also in large scale. This has been demonstrated by a new study published in the Astrophysical Journal  last October, which found that hundreds of galaxies were rotating in sync with the motions of galaxies that were tens of millions of light years away.

This is a new discovery and a new phenomenon that came from studying 445 galaxies within 400 million light years of our planet. The observed coherence is quite astonishing, and the authors hypothesize that it must have something to do with “large scale structures” that are perhaps connecting them, causing them to move so precisely in sync as they do, especially given the fact that the galaxies observed are separated by approximately 20 million light years. Somehow they “directly interact with each other,” said Joon Hyeop Lee, an astronomer at the Korea Astronomy and Space Science Institute.

advertisement - learn more

The paper suggests that the synchronized galaxies are somehow embedded along the same ‘large scale structure,’ which is slowly rotating in a counter-clockwise direction and could be an explanation for the coherence seen between the rotation of these galaxies and their neighbours.

Obviously, a lot is still unknown.

“The dynamical coherence even out to millions of light-years was unexpected and surprising to us, because such distances are obviously too far for neighbor galaxies to directly interact with each other” says Joon Hyeop Lee, first author of the study, from KASI at Daejeon, Korea “Nevertheless, since the observational evidence supports the interaction origin of the dynamical coherence, we could not but think of the possibility that it is the vestige of past interactions.” (source)

These large structures are, as of now, invisible. Astronomers can’t identify what they are, but the discovery hints to the idea that the structures are made predominately of dark matter that links these galaxies in some sort of cosmic web, as galaxies and space in general seem to be dominated by dark matter.

This is where the world of non-material science comes in, as we start to bridge the gap that seems to separate science and metaphysics.

More is unknown than is known. We know how much dark energy there is because we know how it affects the universe’s expansion. Other than that, it is a complete mystery. But it is an important mystery. It turns out that roughly 68% of the universe is dark energy. Dark matter makes up about 27%. The rest – everything on Earth, everything ever observed with all of our instruments, all normal matter – adds up to less than 5% of the universe. Come to think of it, maybe it shouldn’t be called “normal” matter at all, since it is such a small fraction of the universe.

Non-material, invisible substances dominate our world — they are not perceivable to the senses, but they can be detected.

If you’ve looked into dark matter, you may also know that what scientists refer to as the quantum vacuum is often mistaken for dark matter or ‘dark energy,’ but we don’t hear about this in mainstream channels.

Space is actually not empty and it’s full of energy… The energy in space is not trivial, there’s a lot of it and we can actually calculate how much energy there is in that space and that reality might actually come out of it. Everything we see is actually emerging from this space. – Nasim Haramein

This idea was illustrated decades ago with the “Casimir Effect,” which demonstrates what’s called zero-point energy. Today, we are beginning to see that these concepts are not just theoretical, but instead are very practical. (source)(source) This is why it’s interesting to point out how multiple scientists, over the past little while, have been expressing the idea that what we call “Dark Matter” might actually be mistaken for this ‘zero-point energy.’

Take, for example, this Defense Intelligence Agency unclassified document entitled “Warp Drive, Dark Energy & The Manipulation of Extra-Dimensions,” written and prepared for the agency by senior research physicist Richard K. Obousky, Ph.D. and Eric W. Davis, Ph.D.

When it comes to dark energy, here’s what the paper states:

This is what now is being accepted as the ‘substance’ of space. Space is not empty–if you look at an atom, it’s mostly made up of ’empty space,’ but the space is not actually empty, it’s full of energy.

Nikola Tesla was well aware of this substance/force at the turn of the 20th Century:

All perceptible matter comes from a primary substance, or tenuity beyond conception, filling all space, the akasha, or luminiferous ether, which is acted upon by the life-giving Prana or creative force, calling into existence, in never-ending cycles all things and phenomena.” – Nikola Tesla, Man’s Greatest Achievement, 1907

The late Parahamsa Tewari recently had a paper published in Physics Essays. The paper is titled “Structural Relation Between The Vacuum Space and The Electron.” You can access the full study here. Tewari also points out that dark matter has been mistaken for the ether.

Ether has got to be, once again, established, then there will be the meaningful understanding of physics, meaningful understanding of metaphysics, and meaningful understanding of spiritual processes.” – Tewari (source)

I believe that there is something non-physical connecting these galaxies, connecting space and connecting time in ways that we are just beginning to understand, and I believe that what’s beyond this non-physical ‘substance’ is consciousness.

The Takeaway

Science still has a long way to go with regards to making discoveries about our universe, as there are many more questions than answers, but something seems to be a common theme, and that’s the fact that invisible forces like dark matter, dark energy, and the zero-point energy field are key components with regards to the structure and nature of reality.

What’s even more fascinating? The fact that consciousness itself may play an integral role in shaping how our physical world behaves. You cannot go into quantum physics without diving into consciousness. Max Planck, the theoretical physicist credited with originating quantum theory — a feat that won him the Physics Nobel Prize in 1918 — offers perhaps the best explanation for why understanding consciousness is so essential: “I regard consciousness as fundamental. I regard matter as derivative from consciousness. We cannot get behind consciousness. Everything that we talk about, everything that we regard as existing, postulates consciousness.”(source)

Perhaps the universe itself is conscious?

Free Docu-series - Supplements Revealed

Over the past year, Revealed Films has been filming researchers, medical professionals, scientists, athletes, executives, moms, advocates, and many more to clear the air on all things supplements. The global viewing event for Supplements Revealed is finally here and we want you to see it - February 18-28.

Click To Register Free

Continue Reading
advertisement - learn more
advertisement - learn more

Video

Pod

Elevate your inbox and get conscious articles sent directly to your inbox!

Choose your topics of interest below:

You have Successfully Subscribed!