It’s no secret that many pharmaceutical drugs have life-threatening side effects, but oftentimes they aren’t discussed when the medication is being prescribed to the patient. It’s important that, when taking any pharmaceutical drug, you weigh the pros and cons of taking the drug, because when it comes to pharmaceuticals, the benefits don’t always outweigh the risks.
Sometimes, the wrong drugs will be prescribed to patients, but it isn’t very often that Big Pharma companies get caught literally conspiring to do so. Pharmaceutical company Insys Therapeutics is currently under investigation for making it look like patients had cancer (when they did not) so they could sell their opioid drugs to them.
The Big Pharma corporation used a variety of tactics to trick both medical staff and patients, including falsifying medical records, misleading insurance companies, and bribing doctors, all of which is outlined in a federal indictment on the United States Department of Justice website.
How Insys Faked Cancer Patients to Push Deadly Drugs for Profit
Shortly after Insys was given approval to sell their opioid drug, they found one very significant problem. Their drug, a sprayable form of fentanyl called Subsys, was designed to treat cancer patients with acute pain. However, they soon found that their market of cancer patients wasn’t quite big enough to match their profit goals, so they started falsifying information to make it look like patients had cancer so they could sell more of their drug.
The U.S. Department of Justice document reads:
Several pharmaceutical executives and managers, formerly employed by Insys Therapeutics, Inc., were arrested today on charges that they led a nationwide conspiracy to bribe medical practitioners to unnecessarily prescribe a fentanyl-based pain medication and defraud healthcare insurers.
Whenever someone needed prior authorization for Subsys, instead of someone from an actual doctor’s office calling the insurance companies, an Insys employee would. The insurance companies were tricked into thinking that they were talking to someone qualified, as Insys employees had a very strategically worded script to give them that impression and would hide their caller ID.
The most crucial element of their scheme surrounded the question of whether the patient had acute pain caused by cancer, referred to as “breakthrough pain.” Subsys is a drug for cancer patients, and so insurance companies needed to ensure that the patient indeed had cancer. Insys would strategically answer this question by implying that the patient had cancer without specifically saying so.
The authorities have a recording of such a call, which is frankly astonishing to listen to. It’s easy to see how the Insys employees got around answering this question but still made it seem like the patient had “breakthrough pain” from cancer.
You can listen to that recording here, which involves a conversation between an Insys employee and an insurance company regarding a New Jersey patient named Sarah Fuller, who was not diagnosed with cancer but was still prescribed Subsys by her doctor. Fuller actually passed away of a Subsys overdose, and her doctor’s license is currently in the process of being suspended.
You can hear the Insys employee stating that Subsys is “intended for the management of breakthrough cancer pain” without actually stating that the patient herself has cancer. The Insys employee also explains that Fuller experiences “breakthrough pain,” but doesn’t actually say the word “cancer.” It’s tricky wording like this that leads the insurance representatives to believe that the patient has cancer, when in reality they don’t.
This fraud and corruption is not going to be swept under the rug, though. Six former Insys higher-ups and employees have already been charged, including the former CEO, with fraud and racketeering crimes in relation to the drug Subsys.
Prosecutors described the situation as a “nationwide conspiracy to bribe medical practitioners to unnecessarily prescribe a fentanyl-based pain medication and defraud health care insurers.”
Special agent Harold Shaw of the FBI explained:
As alleged, top executives of Insys Therapeutics, Inc. paid kickbacks and committed fraud to sell a highly potent and addictive opioid that can lead to abuse and life threatening respiratory depression. In doing so, they contributed to the growing opioid epidemic and placed profit before patient safety. These indictments reflect the steadfast commitment of the FBI and our law enforcement partners to confront the opioid epidemic impacting our communities, while bringing to justice those who seek to profit from fraud or other criminal acts.
Since then, more federal charges have been announced against those connected to Subsys, and numerous state attorneys have filed their own lawsuits against other employees implicated. Though the six executives charged all pled not guilty, other employees have pled guilty.
Two months ago, former Insys regional manager Karen Hill pled guilty, giving the court details about how she trained employees to convince doctors to collude with the company.
“She gave examples that some of her doctors were motivated by money, chocolate, and spending time with her,” federal prosecutors stated in a release regarding her plea. “When the sales representative asked Hill how to identify doctors who were financially motivated to prescribe Subsys, Hill explained that she looks for doctors that are ‘money hungry,’ and went on to describe how to figure out if a doctor has a ‘light in their eyes’ and is willing to ‘play ball.’ “
“Patient safety is paramount and prescriptions for these highly addictive drugs, especially Fentanyl, which is among the most potent and addictive opioids, should be prescribed without the influence of corporate money,” noted United States Attorney Carmen M. Ortiz. “I hope that today’s charges send a clear message that we will continue to attack the opioid epidemic from all angles, whether it is corporate greed or street level dealing.”
It’s inspiring to see that the justice system is taking this form of corruption seriously, especially with an industry as large and powerful as Big Pharma. However, this isn’t the first time doctors were paid money to push opioids or other pharmaceutical drugs.
A recently published study in the American Journal of Public Health demonstrated just how deep this problem of the doctor-opioid relationship runs, proving that opioids represent a lucrative business for both physicians and Big Pharma.
The study found that an astonishing 1 in 12 doctors has received money from drug companies marketing opioid pharmaceuticals. Between August 2013 and December 2015, researchers at Boston Medical Center found that 68,177 doctors were paid a combined amount of $46 million from drug companies marketing these drugs. You can read more about that in our CE article here.
You can even figure out exactly how much your personal doctor gets paid to sell you drugs, regardless of whether or not they’re opioids or any other pharmaceutical drug. You can read more about that in our CE article here and discover how much Big Pharma pays your doctor to prescribe you drugs.
Although the U.S. government has been lenient toward Big Pharma in the past, the situation with Insys clearly illustrates that they can and will take a stand against Big Pharma. Let’s hope that this trend continues into the future!
This entire situation also puts the doctor-patient relationship into question, and makes you wonder why it is that doctors are compensated when you’re sick rather than when you’re cured or feeling better. Doctors’ jobs are supposedly to help cure you, so shouldn’t doctors be paid when they get you off drugs, because that would imply they’ve helped cure you, not to get you on them?
The opioid epidemic is also a huge issue in and of itself, and I’d encourage you to read the following articles so you can get a better understanding of how Big Pharma and the U.S. government played fundamental roles in creating it.
It’s no secret that there’s an opium epidemic plaguing North America, and it’s been a growing issue for decades. Many people often picture drug dealers as these scary individuals selling pills on streets, when in reality, the drug pushers responsible for the abuse of opioids, opium, and heroin are largely the U.S. government, pharmaceutical companies, and doctors.
That’s right: The U.S. government and physicians are deeply connected to the opium trade. You have physicians as well as Big Pharma heavily pushing and marketing opioids, and then you have the U.S. government governing the opium trade. It’s very clear that we need a shift in values in the medical industry, from focusing on profit to focusing on healing.
To learn more, please read the following CE articles:
Prince Harry: “I Will Not Be Bullied Into Playing A Game That Killed My Mom”
- The Facts:
Last week Prince Harry and Meaghan Markle announced that they would be stepping down from their royal duties, and ultimately their life as royals.
- Reflect On:
Why do so many view powerful figures like the Royal's as gods? Is it time to end this type of perception?
Last week Prince Harry and Meaghan Markle announced that they would be stepping down from their royal duties, and ultimately their life as royals. This is pretty huge news. In regards to what prompted this decision there is certainly a lot we could speculate over, perhaps they want to distance themselves from the royal family because of the recent scandal involving Uncle Prince Andrew and the allegations against him being involved in child sex trafficking, maybe they simply want to get out of the public eye, or perhaps they see how the monarchy has already started to crumble and want to get out while they can.
Whatever the reason may be, it certainly seems to validate the massive shift in consciousness that is currently taking place on our planet and perhaps throughout the entire Universe. Some people have already been calling for the abolishment of the British monarchy after the Queen passes away, as many feel this system is very archaic in this day and age.
On The Surface
It was reported that the Queen had no idea of Harry and Meaghan’s decision before it was announced, and inside sources have told reporters that the “monarchy has never been seen in such a bad state.” (source)
Longtime friend of Prince Harry, JJ Chalmers, made an insightful comment during an interview on BBC’s The One on January 10th, stating that he feels Harry likely made this decision in order to “protect his family” and was simply attempting to put his family first and do what was right for them. The details regarding what Harry might be wanting to “protect his family” from weren’t disclosed.
A video that has gained a lot of popularity on social media over the past week or so, being retweeted over 70,000 times since being posted on January 8th, is an interview of Harry himself discussing the need to protect his family.
Prince Harry said what he said and I’m here to remind you. Period. pic.twitter.com/t1dyZ8Tt3A
— . (@meghanysl) January 9, 2020
In another clip from that same interview we can clearly hear Harry saying that, “I will not be bullied into playing the same game that killed my mom.”
“I will not be bullied into playing a game that killed my mom” OOF pic.twitter.com/DBK1sNXDZn
— Nardos (@lvnlavidanardos) January 10, 2020
How’s The Queen Taking The News?
This past Monday, January 13th a meeting took place to address Harry’s decision. According to CNN.com,
The highly unusual meeting was called after the couple’s bombshell announcement last week that they wished to step back from their roles as senior members of the royal family. The Queen was joined at the summit by Prince Charles, Prince William and Prince Harry, while Meghan was due to have dialed in from Canada.
After a crisis meeting of senior royals at the Queen’s Sandringham estate north of London, the Queen said she had agreed that Prince Harry and Meghan could split their time between the UK and Canada but that “complex matters” would have to be resolved. The monarch said she had ordered final plans to be drawn up in the next few days.
In a statement after the meeting, the Queen said the family would have preferred the couple to “remain full-time working members of the royal family,” but that they “respect and understand” Prince Harry and Meghan’s “wish to live a more independent life.”
The Queen said the family had “very constructive discussions on the future of my grandson and his family” during the meeting, adding that they are “entirely supportive of Harry and Meghan’s desire to create a new life as a young family.”
There were “complex matters for my family to resolve,” and no final agreement had been reached, particularly over Harry and Meghan’s desire to become “financially independent.”
“There is some more work to be done, but I have asked for final decisions to be reached in the coming days,” the Queen said in the statement.
Going A Bit Deeper
When we look at what happened to “the game that killed William and Harry’s mum,” she was harassed relentlessly by the media, and ultimately ended in a fatal car crash. However, there is a lot of controversy behind this official story. Many believe that Princess Diana was against the monarchy in some ways and was attempting to break free from it’s clutches and even potentially expose some of their secrets, and thus believe that her death was no accident, but rather that she was silenced by being taken out by the Royal family.
Are Harry and Meaghan stepping away because they refuse to continue to be harassed by paparazzi, or are they making a bold statement and declaring their values by taking a stance that shows that they no longer wish to be affiliated with or support the Royal family? Could this signify the beginning of the end for the British monarchy? Only time will tell.
Scientists Share Facts About Vaccines At World Health Organization Conference For Vaccine Safety
- The Facts:
Many scientists presented facts about vaccines and vaccine safety at the recent Global Health Vaccine Safety summit hosted by the World Health Organization in Geneva, Switzerland.
- Reflect On:
Why are so many people fighting against each other? Why are there "pro-vax" and "anti-vax" groups? Are these terms not useless? Do they prevent us from having discussions that need to be had and moving forward appropriately?
According to organizations like the American Medical Association as well as the World Health Organization, vaccine hesitancy among people, parents, and, as mentioned by scientists at the World Health Organization’s recent Global Vaccine Safety Summit, health professionals and scientists continues to increase. This is no secret, as vaccines have become a very popular topic over the past few years alone. In fact, the World Health Organization has listed vaccine hesitancy as one of the biggest threats to global health security.
The issue of vaccine hesitancy is no secret, for example, one study (of many) published in the journal EbioMedicine outlines this point, stating in the introduction:
Over the past two decades several vaccine controversies have emerged in various countries, including France, inducing worries about severe adverse effects and eroding confidence in health authorities, experts, and science (Larson et al., 2011). These two dimensions are at the core of the vaccine hesitancy (VH) observed in the general population. VH is defined as delay in acceptance of vaccination, or refusal, or even acceptance with doubts about its safety and benefits, with all these behaviors and attitudes varying according to context, vaccine, and personal profile, despite the availability of vaccine services (Group, 2014,Larson et al., 2014, Dubé et al., 2013). VH presents a challenge to physicians who must address their patients’ concerns about vaccines and ensure satisfactory vaccination coverage.
At the conference, this fact was emphasized by Professor Heidi Larson, a Professor of Anthropology and the Risk and Decision Scientist Director at the Vaccine Confidence Project. She is referenced, as you can see, by the authors in the study above. At the conference, she emphasized that safety concerns among people and health professionals seem to be the biggest issue regarding vaccine hesitancy.
She also stated,
The other thing that’s a trend, and an issue, is not just confidence in providers but confidence of health care providers, we have a very wobbly health professional frontline that is starting to question vaccines and the safety of vaccines. That’s a huge problem, because to this day any study I’ve seen… still, the most trusted person on any study I’ve seen globally is the health care provider, and if we lose that, we’re in trouble.
She also brought up her belief that safety studies are incomplete, and that to continue to refer people to the same old science on safety is not adequately addressing their new concerns because better studies need to be done. Furthermore, she recommended that doctors and professionals forego name-calling with ‘hostile language’ such as “anti-vax”. She recommended encouraging people to ask questions about vaccine safety. After all, it makes sense–in order to make our vaccines safer and more effective, you would think everybody would be on board with constant questioning and examination. After all, that’s just good science, and it’s in everyone’s best interest.
Another interesting point that caught my attention was brought up by Dr. Martin Howell Friede, Coordinator of Initiative For Vaccine Research at the World Health Organization. He brought up the topic of vaccine adjuvants like thimerosal or aluminum, for example. In certain vaccines, without these adjuvants the vaccine simply doesn’t work. Dr. Friede mentioned that there are clinical studies that blame adjuvants for adverse events seen as a result of administering vaccines, and how people in general often blame adverse reactions to vaccines being the result of the vaccine adjuvant. He mentioned aluminum specifically.
He showed concern given the fact that “without adjuvants, we are not going to have the next generation of vaccines.”
He also stated that,
When we add an adjuvant, it’s because it is essential. We do not add adjuvants to vaccines because we want to do so, but when we add them it adds to the complexity. And I give courses every year on ‘how do you develop vaccines’ and ‘how do you make vaccines’ and the first lesson is, while you are making your vaccine, if you can avoid using an adjuvant, please do so. Lesson two is, if you’re going to use an adjuvant, use one that has a history of safety, and lesson three is, if you’re not going to do that, think very carefully.
Furthermore, he criticized the assumption that if an adjuvant like aluminum appears to be safe for one vaccine, that it should be not be presumed to be safe for other vaccines. Dr. Friede said that current safety surveillance is quite effective at determining immediate effects (such as immediate injury to the arm at the injection site), but not as effective in identifying “systemic” long term adverse events.
When I heard him mention lesson two, that “if you’re going to use an adjuvant, use one that has a history of safety,” it instantly reminded me of aluminum because it’s an adjuvant used in multiple vaccines like the HPV vaccine, for example, but has no history of safety.
A study published as far back as 2011 in Current Medical Chemistry makes this quite clear, emphasizing that,
Aluminum is an experimentally demonstrated neurotoxin and the most commonly used vaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants, medical science’s understanding about their mechanisms of action is still remarkably poor. There is also a concerning scarcity of data on toxicology and pharmacokinetics of these compounds. In spite of this, the notion that aluminum in vaccines is safe appears to be widely accepted. Experimental research, however, clearly shows that aluminum adjuvants have a potential to induce serious immunological disorders in humans. (source)
The key sentence here is that “their mechanisms of action is still remarkably poor.” Based on what Dr. Friede said at the conference, it really makes you think.
A study published in BMC Med in 2015 found that “Evidence that aluminum-coated particles phagocytozed in the injected muscle and its draining lymph nodes can disseminate within phagocytes throughout the body and slowly accumulate in the brain further suggests that alum safety should be evaluated in the long term.”
This brings me to another point made at the conference by many scientists in attendance, which was that according to some of them, vaccines seem to lack the appropriate safety testing. This is another big reason why people are so confused and have voiced their concerns about safety, as mentioned above by Professor Larson.
Marion Gruber, PhD and Director of the FDA Office of Vaccines Research and Review, questioned the scope of vaccine safety surveillance and monitoring during pre-licensing vaccine trials as well during the conference.
One source of confusion might be that ‘high-ranking’ health authorities sometimes making conflicting statements. For example, Soumya Swaminathan, MD and Chief Scientist at the World Health Organization, stated at the conference,
I don’t think we can overemphasize the fact that we really don’t have very good safety monitoring systems in many countries and this adds to the miscommunication and the misapprehensions because we’re not able to give clear cut answers when people ask questions about deaths that have occurred due to particular vaccines… One should be able to give a very factual account of what exactly is happening, what the cause of deaths are, but in most cases there’s some obfuscation at that level and therefore there’s less and less trust then in the system.
Prior to this statement, in a promotional video released just days before the conference began, she stated that “we have vaccine safety systems, robust vaccine safety systems.”
She completely contradicted herself.
If you’d like access to the entire conference, you can do so at the World Health Organization’s website.
The scientific community should never stop questioning, especially when it comes to medication. Based on the information that’s come out at this conference, it’s quite clear that there is a lot of room for improvement when it comes to the development of vaccines and vaccine safety overall. Discussion is always encouraging, as long as it’s peaceful and facts are presented like they were at this conference. It’s better to understand the reasons why a lot of people are hesitant about vaccination and appropriately respond, instead of simply using ridicule and hatred because that’s never effective and both parties cannot move forward that way. At the end of the day, scientists should never cease to question.
Gulf War Illness Tied To Cipro Antibiotics
Civilians suffering from Fluoroquinolone Toxicity Syndrome (an adverse reaction to a fluoroquinolone – Cipro/Ciprofloxacin, Levaquin/Levofloxacin, Avelox/Moxifloxacin, Floxin/Ofloxacin and others) have noted the similarities between Gulf War illness and Fluoroquinolone Toxicity Syndrome for years. It is beyond likely, it is probable, that they are one in the same.
The VA defines Gulf War Illness as “chronic, unexplained symptoms existing for 6 months or more” that are at least ten percent disabling. The CDC case definition of Gulf War Illness “requires chronic symptoms in two of three domains of fatigue, cognitive-mood, and musculoskeletal.”
Fluoroquinolone Toxicity Syndrome is a chronic, unexplained illness with symptoms lasting for months, years, or, as the updated warning label notes, permanently. The symptoms of Fluoroquinolone Toxicity Syndrome are too numerous to list, but a cursory glance at the warning label for Cipro/Ciprofloxacin will tell you that the effects include musculoskeletal problems and central nervous system issues. Additionally, as pharmaceuticals that damage mitochondria, the energy centers of cells, severe fatigue is often induced by Fluoroquinolones.
A 1998 study entitled, “Chronic Multisymptom Illness Affecting Air Force Veterans of the Gulf War,” found that the most commonly reported symptoms of Gulf War Illness are sinus congestion, headache, fatigue, joint pain, difficulty remembering or concentrating, joint stiffness, difficulty sleeping, abdominal pain, trouble finding words, (feeling) moody or irritable, rash or sores, numbness or tingling and muscle pain.
A 2011 study conducted by the Quinolone Vigilance Foundation found that the most commonly reported symptoms of Fluoroquinolone Toxicity Syndrome are tendon, joint, and muscle pain, fatigue, popping/cracking joints, weakness, neuropathic pain, paresthesia (tingling), muscle twitching, depression, anxiety, insomnia, back pain, memory loss, tinnitus, muscle wasting.
The symptoms are similar enough to raise a few eyebrows. It should be noted that when a chronic, multi-symptom illness suddenly sickens a patient or a soldier, and he or she goes from being healthy and active to suddenly being exhausted and unable to move or think, it is difficult to pinpoint and describe exactly what is going wrong in his or her body. Thus, even if the symptoms are identical, they may not be described in an identical way because of context and differing areas of focus.
For victims of fluoroquinolones, it is as if a bomb went off in the body of the victim, yet all tests come back “normal” so in addition to physical pain and suffering that the soldier/patient is going through, he or she has to suffer through dismissal and denial from medical professionals as well. Neither Gulf War Illness nor Fluoroquinolone Toxicity Syndrome are detected by traditional medical tests and thus both diseases are systematically denied. All blood and urine markers come back within the normal ranges, yet the patient or soldier is suddenly incapable of 90% of what he or she used to be able to do. When a large number of patients or soldiers (nearly 30% of the soldiers serving in the Gulf reported symptoms. Exact numbers of civilian patients suffering from Fluoroquinolone Toxicity Syndrome are unknown because of delayed reactions, misdiagnosing the illness, tolerance thresholds, etc.) experience adverse reactions that are undetectable using the tests available, there is something wrong with the tests. The patients and soldiers aren’t lying and their loss of abilities isn’t “in their heads.”
Exposure to the same Poison
Another glaring similarity between Gulf War Illness and Fluoroquinolone Toxicity Syndrome is that everyone with either syndrome took a Fluoroquinolone.
Per a Veteran of the Marines who commented on healthboards.com about the use of Ciprofloxacin by soldiers in the Gulf:
“The Ciprofloxacin 500 mg were ordered to be taken twice a day. The Marines were the only service that I know for sure were given these orders. We were ordered to start them before the air war, and the order to stop taking them was giver at 0645 Feb 28th 1991 by General Myatt 1st Marine div commander. We were forced to take Cipro 500mg twice a day for 40 plus days. so the Marines were given NAPP (nerve agent protection pills) or pyridiostigmine bromide to protect us from nerve agent, and We were ordered to take the Cipro to protect from anthrax. We were part of the human research trial conducted by the Bayer corporation in the creation of their new anthrax pills. At that time they had no idea of the side effects of flouroquinolones. That’s the class of medications that Cipro falls into. After the Gulf War the FDA and Bayer co. started releasing the list of side effects. You do need to know what was done to you so you will have to do your own research. Good luck to all of you and Semper Fi.”
By definition, everyone who suffers from Fluoroquinolone Toxicity Syndrome has taken a fluoroquinolone – Cipro/Ciprofloxacin, Levaquin/Levofloxacin, Avelox/Moxifloxacin or Floxin/Ofloxacin. Civilians are also part of the “human research trial conducted by the Bayer corporation” as well as Johnson & Johnson, Merck and multiple generic drug manufacturers who peddle fluoroquinolones as “safe” antibiotics.
The Case Against Fluoroquinolones
Of course, there were multiple chemicals and poisons that Gulf War Veterans were exposed to in the 1990-91 Persian Gulf War and thus it has been difficult to pinpoint an exact cause of Gulf War Illness. The ruling out of the following possible causes should certainly be questioned thoroughly, but “depleted uranium, anthrax vaccine, fuels, solvents, sand and particulates, infectious diseases, and chemical agent resistant coating” have been found not to cause Gulf War Illness. Other potential causes of Gulf War Illness include oil fires, multiple vaccines, pesticides, and, of course, fluoroquinolone antibiotics (Cipro). (It should be noted that non-deployed military personnel who served during the Gulf War period, but who were not deployed in the Middle East, have also been afflicted with Gulf War Illness and thus toxins that both deployed and non-deployed personnel have been exposed to should be the focus of investigations into the causes of Gulf War Illness.)
The Air Force Times article is one of the first official mentions of the relationship between Cipro and Gulf War Illness. Officially, the link hasn’t been examined (though some very smart researchers are building a case as you read this). Why Cipro hasn’t been looked at as a potential cause of Gulf War Illness is a question that I don’t know the answer to. Perhaps it’s because most people think that all antibiotics are as safe as penicillin. Perhaps it’s because most people have a tolerance threshold for fluoroquinolones and don’t react negatively to the first prescription that they receive. Perhaps it’s because even today, more than 30 years after Cipro was patented by Bayer, the exact mechanism by which fluoroquinolones operate is still officially unknown (1). Perhaps it’s because it is unthinkable that a commonly used antibiotic could cause a chronic syndrome of pain and suffering. Perhaps it’s because the tests that show the damage done by fluoroquinolones aren’t used by the VA or civilian doctors’ offices. Perhaps it’s because fluoroquinolones are the perfect drug – they take an acute problem – an infection, and convert it into a chronic disease-state that is systematically misdiagnosed as fibromyalgia, chronic fatigue syndrome, an autoimmune disease, leaky gut syndrome, insomnia, anxiety, depression, etc. and turns formerly healthy people into lifetime customers of the medical establishment / pharmaceutical companies. Perhaps it is simply widespread ignorance about the way these dangerous drugs work.
The Cliffs Notes version of how fluoroquinolones work is as follows:
The fluoroquinolone depletes liver enzymes that metabolize drugs (CYP450) (2). When the enzymes are depleted sufficiently, the fluoroquinolone forms a poisonous adduct to mitochondrial DNA (mtDNA) (3, 4), which destroys and depletes mtDNA (5). While the mtDNA is being destroyed, the fluoroquinolone is also binding to cellular magnesium. (6, 7) The mitochondria reacts to being assaulted by producing reactive oxygen species (ROS) (8, 9). Some of the ROS, specifically hydrogen peroxide, combines with the excess calcium (there is a balance in cells of magnesium and calcium and the binding of the magnesium results in an excess of calcium) to induce the expression of CD95L/Fas Ligand (5) which then causes cell death (apoptosis) and immune system dysfunction (10) which leads the body to attack itself – like an autoimmune disease.
Damage is caused by every single step in the process. Additional damage may be done by the fluorine atom that is added to fluoroquinolones to make them more potent. It should be noted that the complexity of these cellular interactions is too vast to write up in this article.
Every symptom of Gulf War Illness is consistent with mitochondrial damage and oxidative stress (11), both of which have been shown to be brought on by fluoroquinolones.
Though the tests used in typical medical practice show no reason for victims of fluoroquinolones to be ill, that fact simply shows that the wrong tests are being used. Tests of mitochondrial function, antioxidant/oxidant ratios and DNA will show the damage that is done by fluoroquinolones. The way to determine whether Cipro is the cause of Gulf War Illness is to conduct a DNA mass spectrogram analysis on afflicted Gulf War Veterans. If the DNA mass spectrogram analysis shows that quinolone molecules have adducted to the DNA of the Veterans, that’s a smoking gun of damage done by Cipro.
Millions of civilians have also been hurt by fluoroquinolones. I can connect fluoroquinolones to almost every chronic disease that has increased in prevalence since the introduction of fluoroquinolones to the mass population in the mid-1980s. Additionally, DNA is damaged and thus the effects are intergenerational and many of the chronic diseases that plague children can be linked to fluoroquinolone use by parents.
Some very well-respected researchers are working on more furthering the case that Cipro is responsible for Gulf War Illness. If any Gulf War Veterans want to take on Bayer before those studies are released, the way to do so is through obtaining a DNA mass spectrogram analysis and having it analyzed by a toxicologist. It is proof of damage and it is necessary. When that proof is obtained, I encourage all Gulf War Veterans to use it to fight those who poisoned them – Bayer and their corroborators in the DOD and the FDA.
To any Gulf War Veterans who read this – you are soldiers and you are warriors. I know that you have been weakened, but you are still alive and those of you who can fight, should, because a grave injustice has been done to you. It is an injustice that is also being inflicted on innocent civilians. There is nothing okay about the poisoning of our military men and women, or the American public, with chemotherapy drugs masquerading as antibiotics. I encourage you to fight Bayer and their corroborators like what they are – domestic terrorists. It is a fight that you can win. The truth, and a significant amount evidence, are on your side.
Post Script: The author’s web site, with more information about fluoroquinolones, is www.floxiehope.com. Further information about fluoroquinolones can be found through the Quinolone Vigilance Foundation – www.saferpills.org.
- Inorganic Chemistry, “New uses for old drugs: attempts to convert quinolone antibacterials into potential anticancer agents containing ruthenium.”
- FDA Warning Label for Ciprofloxacin
- The Journal of Biological Chemistry, “The Mechanism of Inhibition of Topoisomerase IV by Quinolone Antibacterials.”
- Findings of Toxicologist Joe King
- The Journal of Immunology, “Mitochondrial Reactive Oxygen Species Control T Cell Activation by Regulating IL-2 and IL-4 Expression: MechanismN of Ciprofloxacin Mediated Immunosuppression“
- Antimicrobial Agents and Chemotherapy, “Effects of Magnesium Complexation by Fluoroquinolones on their Antibacterial Properties”
- Proceedings of the National Academy of Sciences of the United States, Biochemistry, “Quinolone Binding to DNA Mediated by Magnesium Ions”
- Science Translational Medicine, “Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells“
- Journal of Young Pharmacists, “Oxidative Stress Induced by Fluoroquinolones on Treatment for Complicated Urinary Tract Infections in Indian Patients“
- Antimicrobial Agents and Chemotherapy, “Ciprofloxacin Induces an Immunomodulatory Stress Response in Human T Lymphocytes“
- Nature Precedings, “Oxidative Stress and Mitochondrial Injury in Chronic Multisymptom Conditions: From Gulf War Illness to Autism Spectrum Disorder”
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