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Doctor Explains What Happens To The Human Body When It Goes Into Ketosis (Ketogenic Diet)

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*Latest article published on this topic with important information to consider: Doctor Explains Why She Never Recommends The Ketogenic Diet*

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From a young age we’re taught that eating three meals a day, plus snacks, is healthy and necessary for the human body to function normally, and this rhetoric still dominates North American food guides today. Mark Mattson, the Current Chief of the Laboratory of Neuroscience at the National Institute on Aging, once asked:

Why is it that the normal diet is three meals a day plus snacks? . . . There are a lot of pressures to have that eating pattern, there’s a lot of money involved. The food industry – are they going to make money from skipping breakfast like I did today? No, they’re going to lose money. If people fast, the food industry loses money. What about the pharmaceutical industries? What if people do some intermittent fasting, exercise periodically and are very healthy? Is the pharmaceutical industry going to make any money on healthy people?

The quote above comes from a TED talk Mattson gave on the benefits of fasting, a practice which forces the body to switch its fuel source from glucose to ketones. Scientists are observing a wide variety of health benefits from this transition, from starving cancer to improving cognition, and a ketosis diet is now being implemented for people with cancer, Alzheimer’s disease, epilepsy, and more. It has tremendous benefits for the brain, as explained by Mattson in his talk, but also for the body.

What Is Ketosis?

The human body only has two fuel sources, fat and glycogen (sugar). When we have a lot of sugar stored in the body (from consuming carbohydrates, for example, which turn into sugar), our body uses that sugar to feed our brain and other organs, providing the energy they need to function.

When the body runs out of glucose, it switches energy sources, from glycogen to fat. This can only happen when the body is depleted of its glycogen reserves.

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We’ve been taught for years that the body needs glycogen to operate properly, but as we continue to expand our knowledge, it turns out this might not be the case.

When the body is done running on glycogen, and starts burning its fat reserves, it also produces what are called ketone bodies. These are molecules that are produced by the liver from fatty acids during periods of starvation, fasting, low food intake, carbohydrate restrictive/high fat diets, and long, intense exercise.

As it turns out, these ketone bodies have a wide range of health benefits.

Your Body Will Kill Cancer Cells

In 1923, scientist Otto Warburg hypothesized that cancer was caused by a metabolic process whereby cancer cells fuel their growth “by swallowing up enormous amounts of glucose (blood sugar) and breaking it down without oxygen.” Coined the Warburg Effect, the theory was controversial at the time, but the past few decades have sparked new interest in it, and oncologists now use the dependence on glucose that cancer cells have to locate tumours within a patient’s body.

Warburg made his discovery around the same time the ketogenic diet was found to be beneficial for epilepsy. Studies have shown that when the body produces ketones, they form a protective barrier around the brain, which is why more and more paediatricians are recommending the diet for children with epilepsy. It has a huge success rate, yet, since fasting is neither marketable nor profitable, receives little mainstream attention.

The ketogenic diet incorporates a high fat, low protein, low carbohydrate intake that forces the body into starvation mode. As a result, glucose becomes depleted and the body is forced to produce a new source of energy, one cancer cells cannot feed off. Nutritional manipulation of the body can actually starve tumour cells while maintaining its other tissues by creating protective compensatory mechanisms.

That being said, you can still induce high ketone levels by doing a lot of fasting, and eating healthy, even if you are eating carbs. During your fasting periods, you will still be producing ketones. You can actually measure your blood ketone levels, and you can find out more about that below.

A few years ago, scientists discovered the first evidence of a natural intervention triggering stem cell-based regeneration of an organ or system. The study was published in the June 5 issue of Cell Stem Cell by researchers from the University of Southern California. The research shows that cycles of prolonged fasting protect against immune system damage and induce immune system regeneration. They concluded that fasting shifts stem cells from a dormant state to a state of self-renewal. The study outlines how, during periods of fasting, the body repairs damaged DNA and helps to starve cancer.

If we take a look at a recent study from 2014, published in the journal Trends In Molecular Medicineit outlines and confirms what several studies before it have already done:

  • Caloric restriction (diet high in nutrients but low in calories) and its mimetics (CR) improve lifespan and reduce cancer incidence
  • CR and CR mimetics sensitize cancer cells to chemotherapy
  • CR and CR mimetics combined with chemotherapy enhance anticancer immune responses

According to the study:

Caloric restriction (CR) is currently the most robust environmental intervention known to increase healthy life and prolong lifespan in several models, from yeast to mice. Although the protective effect of CR on the incidence of cancer is well established, its impact on tumor cell responses to chemotherapeutic treatment is currently being investigated. Interestingly, the molecular mechanisms required to extend lifespan upon reduced food intake are being evaluated, and these mechanisms may offer new opportunities for therapeutic intervention. In addition, new findings suggest a beneficial effect of CR in enhancing the efficiency of tumor cell killing by chemotherapeutic drugs and inducing an anticancer immune response.

By fasting, you’re literally cutting off the energy source for cancer cells, and at the same time, while in ketosis, your body is experiencing a wide range of other health benefits.

The first publication tested on a case by case basis in this area was done in 1995, when two young patients received ketogenic diet therapy for their brain tumours. They were unresponsive to standard treatments, yet with this new therapy, both patients’ tumours began consuming less glucose and shrinking in size.

In 2010, a case report was conducted on a 65-year-old woman who had a brain tumour causing numerous neurological deficits. In addition to standard care, she was put on a ketogenic diet. After two months, she experienced a complete remission of her tumour, yet when the diet was suspended, the tumour returned.

Below is a talk between Joe Rogan and Dr. Dom D’Agostino, Ph.D., an assistant professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and a Senior Research Scientist at the Institute for Human and Machine Cognition (IHMC).

D’Agostino discusses what we know about the ketogenic diet today. He recently published a study showing the benefits the diet can have on cancer cells. Here is a 13 minute TEDx talk that’s also pretty informative if you don’t want to listen to the whole podcast below.

Here is an episode of a doctor sharing a different perspective.

A Practical Guide for Getting Started on the Ketogenic Diet

This is also discussed in the podcast above, but a good way to start is with intermittent fasting. This requires one to restrict their eating time to an eight-hour period. For example, if you have your first meal of the day at 12 p.m., your last meal would be before 8 p.m. and then you wouldn’t eat again until the next day. This way, you will gain the benefits of fasting, as long as your eating period is filled with good, healthy foods.

Everybody gets into ketosis differently. If you’re intermittent fasting, your diet will have to be high in healthy fats and low in carbs. But it varies with each individual just how strict they have to be, depending on their lifestyle. For one person, it might take 14 hours to deplete their glucose reserves, for another, it might take 24. The longer you go into a fast, the more ketone bodies you will produce, which is also discussed in the podcast above.

Nutrients are critical here, and it’s not going to work unless you are eating the right foods during your eating periods.

Dr.  D’Agostino’s website is a great resource to learn more about this. It’s essential to research this diet thoroughly before trying at home, and his website includes lots of information and guides for getting started.

Related CE Article: Study Shows What A Ketogenic Diet Did To Mice With Systemic Metastatic Cancer

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Awareness

Johnson & Johnson Found To Have Knowingly Allowed Asbestos In Their Baby Powder

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In Brief

  • The Facts:

    Johnson and Johnson have recently lost lawsuits for negligence in knowingly allowing carcinogenic substances in their talc-based hygiene products.

  • Reflect On:

    Are we starting to turn the page on an era where human health and safety are not the prime considerations in the manufacturing of consumer products?

We are starting to awaken to the fact that it seems to be the rule, and not the exception, that large Western corporations put profits above human health considerations. The only time they seem to give any regard to human health concerns is when their forecasts of potential lawsuits down the road would likely exceed the cost measures needed to ensure the safety of their product.

Johnson & Johnson is just one of a long line of corporate perpetrators who believed that covering up and lying about known health concerns would make better business sense than taking the time and resources to actually address those health concerns within their products.

Contaminated Baby Powder: The Height Of Indignity

One would think, regardless of an understanding that the bottom line is a priority for most private companies, that the health and safety of a nursing mother and her newborn child would be sacrosanct for any industry. The reality is that this is simply not the case, even though J&J could have mitigated this problem from the start.

Companies that mine talc are required to take extra steps to ensure the absence of asbestos in their talc. Instead, J&J allegedly went to great lengths to fake it.

Not only did the company know about the asbestos contamination, evidence suggests, but J&J also failed to warn its customers about the link between Baby Powder and cancer or replace its talc with a safer alternative. As a result, J&J guaranteed its customers’ exposure to asbestos.

And regardless of their size or numbers, asbestos fibers are lethal at any capacity. As the World Health Organization (WHO) has stressed repeatedly, there is no safe level of exposure. (source)

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The Testimony of Scientist James Webber

Baby Powder’s contamination with asbestos (a mineral that naturally occurs near talc) has long been the subject of lawsuits. But only in recent years has evidence begun to unravel J&J’s defense – that the company had no idea – and threatened its success in lawsuits to come.

In March, a California jury awarded $29 million to Terry Leavitt, a woman who said that asbestos in Johnson & Johnson’s talcum-powder-based products caused her terminal mesothelioma. Environmental scientist James Webber testified in her high-profile California trial and made these observations:

During several hours on the stand, Webber explained how he ran tests that showed “clear” evidence of asbestos contamination in the mines from which J&J sourced talc.

“The testing I have seen [shows] that it was present at least as early as 1971 and up through the late 1990s,” said Webber, who ran an asbestos laboratory in New York state.

Despite denying it publicly, J&J had observed this contamination in internal memos. Its notes dismissed the amount of asbestos in its talc as “but a trace,” Webber alleged. But that was just an optimistic interpretation of superficial testing, he said: the tests used methods too weak to detect microscopic asbestos fibers. Webber insisted the actual tests results revealed there could be millions of asbestos fibers per gram of talc.

And J&J’s inaccurate reports were allegedly only the tip of the iceberg. In some instances, Webber said, photos attached to J&J’s reports revealed that “they had been seeing it and not reporting it.”  (source)

And It’s Getting Worse

The $29 million verdict, in California Superior Court in Oakland, was the latest defeat for the healthcare conglomerate facing more than 13,000 talc-related lawsuits nationwide. And things may be getting even worse for J&J, according to ZeroHedge:

Johnson & Johnson shares are down over 5% after Bloomberg reports that, according to people with knowledge of the matter, the U.S. Justice Department is pursuing a criminal investigation into whether Johnson & Johnson lied to the public about the possible cancer risks of its talcum powder…

Now, a grand jury in Washington is examining documents related to what company officials knew about any carcinogens in their products, the people said.

The Takeaway

It seems as though corporations have long been willing to take the calculated risk of short-cuts and denials instead of ensuring that their products are safe for public use. My suspicion is that a part of our collective awakening process will be issuing in a new business paradigm in which human health and safety become paramount.

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Awareness

Prescription Infant Formulas Found To Be Contaminated With Aluminum

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In Brief

  • The Facts:

    Multiple brands of prescription infant formula were found to contain high levels of aluminum.

  • Reflect On:

    Should we be questioning the quality of products that come from pharmaceutical production? Do we veer away from natural methods of raising children more than we should? At what cost?

You may not think aluminum is a big deal, but it is. For anybody who has looked into aluminum toxicology, it’s quite clear and apparent that it has no place inside of any living biological organism. Putting it simply, it wreaks havoc on our biology. High amounts of aluminum have been found in the brains of people with Alzheimer’s disease, with experts in the field believing that aluminum brain accumulation may be one of the main causes of Alzheimer’s disease.

It’s also been discovered within the brains of MS patients, and some of the highest aluminum content ever recorded in brain tissue has also been discovered in people with autism. Aluminum is associated with several diseases. But an adult body can do a great job of flushing out aluminum.

Despite the fact that aluminum has no place within earth’s biota, it’s still present in many of our medications, our food, and even in the water that we drink due to contamination since the industrial revolution. Aluminum inside the body is a new phenomenon and still understudied. Again, there is a threshold, and aluminum that is injected via vaccines doesn’t exit the body–there is strong evidence that it remains inside the body and ends up in distant organs and eventually inside of the brain. If you want to access more studies on that topic, you can read this article I published that provides them and goes into more detail. You can also watch this interview with Christopher Exley, where he also points to that fact.

A new study published in the International Journal of Environmental Research and Public Health has shown that multiple popular infant prescriptions are contaminated with aluminum. You may be asking how much aluminum, but the authors make it a point to stress that there are no safe amounts of aluminum levels that can be inside of a human body, let alone a newborn baby. That being said, the amounts found are listed within the abstract of the study:

Historical and recent data demonstrate that off-the-shelf infant formulas are heavily contaminated with aluminium. The origin of this contamination remains to be elucidated though may be imported via ingredients, packaging and processing. Specialised infant formulas exist to address health issues, such as low birth weight, allergy or intolerance and medical conditions, such as renal insufficiency. The aluminium content of these prescription infant formulas is measured here for the first time. We obtained 24 prescription infant formulas through a paediatric clinic and measured their total aluminium content by transversely heated graphite furnace atomic absorption spectrometry following microwave assisted acid/peroxide digestion. The aluminium content of ready-to-drink formulas ranged from 49.9 (33.7) to 1956.3 (111.0) μg/L. The most heavily contaminated products were those designed as nutritional supplements for infants struggling to gain weight. The aluminium content of powdered formulas ranged from 0.27 (0.04) to 3.27 (0.19) μg/g. The most heavily contaminated products tended to be those addressing allergies and intolerance. Prescription infant formulas are contaminated with aluminium.

Another very important point made right off the bat by the authors:

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Human exposure to aluminium is a serious health concern. Aluminium exposure in infants is understandably a burgeoning issue. While infant exposure to aluminium continues to be documented, its consequences, immediate and in the future, have received only scant attention and research is required to understand the biological availability of aluminium through formula feeding. For example, how much aluminium is absorbed across the neonate gut and its subsequent fate, including excretion.

There is already too much aluminium in infant formulas and herein we have measured its content in a large number of prescription formulas, products which are fed to vulnerable infants in their first months of life. Many of these products are heavily contaminated with aluminium.

As for the specific infant formulas, you can refer to the study. The researchers obtained 24 prescription infant formulas via the Paediatric Clinic of Russells Hall Hospital in Dudley, United Kingdom. The ready-to-drink and powdered products were new, ready-to-be used and unopened samples. These formulas are for babies with some sort of growth restriction, like for preterm infants or infants who have poor weight gain. There were also powdered formulas for allergies and intolerances and powdered formulas with additional amino acids.

The authors contacted each manufacturer and expressed that they denied knowing that there was any aluminum in their products, which means it’s still a mystery as to their source. The authors hypothesize on a number of ways that aluminum could be entering into the formulas.

In their conclusion, the authors emphasize that:

Where possible, breast milk feeding should be prioritised, as the aluminium content of breast milk is invariably an order of magnitude lower than in formula feeds. Where infant formulas are the only source of nutrition for many infants in their first weeks and months of life, aluminium ingested in formula feeds will be the major contributor to their body burden of aluminium. The last thing that vulnerable infants fed specialised formulas for their specific nutritional/medicinal need is additional aluminium in their diet.

Detoxing

There is a lot of information out there on how a person can detox from aluminum and other heavy metals. There are multiple studies, and based on what I’ve looked into, water with high amounts of Silica are effective in draining aluminum out of your body and brain. Herbs like cilantro and substances like chlorella and spirulina are also great for removing some metals. The information is out there, so be sure to do your research.

The Takeaway

It’s concerning to think about what these corporations are doing. Again, aluminum should hold no place in our society, it should’ve remained well below our surface as part of the Earth’s crust for a reason. It wasn’t until humans began digging it out and using it for a number of things, irresponsibly I might add, that we started to see the health implications which still go largely ignored by the medical community.

In fact, heavy metal accumulation and detoxification of aluminum haven’t been addressed at all, which is odd given the fact that heavy metal accumulation is linked to a variety of diseases.

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Awareness

9 Studies You Should Be Aware of Before Trying The Ketogenic Diet

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In Brief

  • The Facts:

    The Ketogenic diet is a popular fad diet that promotes quick weight loss and symptom management for bodies that are dealing with poor lymph, kidney and digestion health.

  • Reflect On:

    Based on the studies that are emerging, is our desire for quick weight loss more important than living a long and healthy life? Are we learning about these diets primarily through those with strong ties to upholding these diets?

The ketogenic diet has popped up as a popular approach to weight loss in the last few years. Is it successful at that? Sure, it is. I’ve experimented with the diet myself years ago when I was looking to lose some belly fat. I was entering into ketosis in a different way than most, as I was not eating any animal products, but it does in fact work.

But like any animal product based diet, what are the consequences of eating so much food that does not truly jive with our human bodies? Not only that, is fast weight loss more important than keeping our morality rate down?

In the last few years, we’ve reported a lot on the Keto diet and the various ways it can be done. We have explored the studies, the results and in some ways, we supported it. But lately, I have been thinking about how supporting this could actually be encouraging people to jump into these diets, including the paleo diet, when in reality these diets increase mortality rates and are not healthy for the human body.

It became a thought in the back of my mind, I have always strived to put the best information out that I can through this platform to promote good health. And so we must look at that, even if that means upsetting some people who currently are on paleo or keto and are seeing some good weight loss or symptom management. The truth is, like the many people I’ve seen crash on these diets after a few years, I want people to know the truth of what’s going on out there. And how we can get beyond diets that symptom manage, and instead get onto diets that truly heal.

Anytime we have fad diets, which paleo and keto are, we see products and bias pop up all over the place to support the continuation of these trends. It becomes less about health and more about upholding an identity or a business.

So as I recently looked into what experts are saying about these diets, I came upon two important videos I think everyone should check out. Both have been embedded below. Remember, it’s not that I care what you choose in your own life, or that I feel there is a right or wrong, it’s that I believe we should be informed and I wish to use this platform to promote as best a message as I can.

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The Videos

Thanks to Plant-Based News for creating such a good channel and resource of information on YouTube.

In this video, several plant-based health experts talk through 9 nutrition studies that would be of interest to low carb keto diet proponents. To read the 9 studies, click here.

Next up, Dr. Kim Williams (past President of the American College of Cardiology) shares his insights about the ketogenic.

Related Articles

Diabetic Shares Why He Quit ‘The Ketogenic Diet’

Doctor Explains Why She Never Recommends The ‘Ketogenic Diet’

The Biggest Misconception About The ‘Ketogenic Diet’…You Don’t Actually Have To Follow It

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