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The GMO Agenda Takes a Menacing Leap Forward with EPA’s Silent Approval of Monsanto/Dow’s RNAi Corn

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Article written by Written by Sayer Ji, founder of Greenmedinfo.com, a reviewer at the International Journal of Human Nutrition and Functional Medicine, Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of the National Health Federation, Steering Committee Member of the Global Non-GMO Foundation

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Without much more than a whisper from the mainstream media, Monsanto’s newest Frankenfood has received full EPA approval and will be arriving on dinner plates by the end of the decade. The implications of this are harrowing, to say the least.

While you may not have made up your mind on the dangers of GMOs, you likely feel entitled to know when you’re consuming a food that is the product of laboratory research. For this reason, I am reporting on Monsanto’s latest food technology, unfortunately, already in the pipeline. And quite silently so. I write this with a certain degree of solemnity, if not also a tinge of regret, because, for three years, I have heard rumblings of Monsanto’s next project – RNA interference technology. It was actually the late Heidi Stevenson, my friend, colleague, and founder of the platform Gaia Health, who first alerted me to the dangers of RNA interference-based tinkering with our food supply when she reported on the near disastrous approval of GMO wheat using RNA interference technology in Australia. Thankfully a few brave scientists and informed public stood up and, together, averted the disaster. But since then, both the dangers and the breakneck speed of development of this technology have gone largely ignored, even among activists deep in the non-GMO movement. In order to truly appreciate the gravity of the situation, and why the EPA’s approval of RNAi corn intended for human consumption, is so concerning, it will first require a little background information on the fascinating topic of non-coding small RNAs, and their formidable relevance to our health.

How Non-Coding, Small RNAs Link Together The Entire Biosphere

One of the most important discoveries of our time is that all plants, including those we use for food and animal feed, contain a wide range of RNA molecules capable of inhibiting gene expression or translation. These non-coding RNA molecules neutralize targeted messenger RNA molecules (mRNAs), which prevents their translation into a protein, i.e. they “silence genes.”

Compelling research has surfaced suggesting that not only do these genome-regulating small RNA molecules exist in our foods, but that they are capable of surviving digestion, and being absorbed into our bodies fully intact where they alter, suppress or silence genes, post-transcriptionally. Moreover, some of these small RNAs — primarily microRNAs (miRNAs) and small interfering RNAs (siRNAs) — are believed to be cross-kingdom mediators of genetic information, making it possible for RNAs in one species impacting many others through both their active and passive exposure to them.

Food therefore is essentially an epigenetic modifier of gene expression, making it a form of information, and not only a source of bodily building blocks and caloric energy, as conventionally understood. As such, any significant changes to food or feed staples within our food chain could have powerful impacts on the physiological fate of those consuming them, essentially rewriting the functionality of our genomic hardware via software like changes in RNA profiles. The entire biosphere, therefore, is held together in a web-like fashion through these molecular RNA messengers, lending a plausible mechanism to the biotic aspect of Lovelock and Margulis’ Gaia theory of Earth as a self-regulating, meta-organism. You can learn more by reading my article Genetic Dark Matter, Return of the Goddess, and the Post-Science Era.

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Monsanto and Co Capitalizing on RNA interference Technology

While this discovery will have profound implications for the field of nutrition and medicine, it has also created enormous interest among biotech and agricultural firms, namely, Monsanto and Dow, looking to capitalize on the design of proprietary products using interference (RNAi) technology. In mid June, last month Monsanto received EPA approval for a type of corn genetically altered to produce an RNA-based pesticidal agent (aka, a plant-incorporated protectant (PIP)) which lethally targets a metabolic pathway within the corn rootworm, known within the industry as the “billion dollar bug.” Branded as Smartstax PRO, the newly minted GMO plant produces a small, double-stranded RNA known as DvSnf7 dsRNA which disrupts a critical gene within the rootworm, causing its death. This was added on top of four other “stacked” GMO traits, such as the ability to produce two other pesticidal proteins (Cry1A.105 and Cry2Ab2), as well as survive exposure to both glyphosate (aka Monsanto’s Roundup 2) and Glufosinate (aka Dow’s Libertylink), highly toxic herbicides. Roundup, for instance, has demonstrated carcinogenicity in the parts per trillion range. Yet, the EPA considers it perfectly safe for consumers to ingest many orders of magnitude higher concentrations than that, proving its function as a cheerleader and not a regulator of the industry that controls our food supply.

The Atlantic, one of the only mainstream news outlets to report on the topic, pointed out how surprisingly low key the approval process was:

“The EPA’s decision attracted little attention from the press or even from environmental groups that reliably come out against new genetically modified crops.”

Bill Freese, The Center for Food Safety’s science policy analyst, told the Atlantic he was caught off guard by EPA’s decision to only allow 15 days of public comment, and the fact that it did not post its decision to the Federal Register, as it customary, especially considering how unprecedented the use of a RNAi insecticide in a plant intended for human consumption is. Monsanto anticipates the new corn will be on the market by the end of the decade.

One would imagine that such revolutionary technology would require short and long-term (decades) of safety testing before licensure. Instead, as is often the case with big-ticket market agendas, the product is being rushed to market. There are already significant biases in place within the EPA and USDA in regard to nucleic acids – assumptions that exempt them from cautionary considerations. RNA is considered Generally Accepted As Safe (GRAS), but this is because it is defined and perceived only as a physical substance rather than as the powerful signaling/informational molecule it is. The EPA’s approval of RNAi food crops ignores the fact that it takes a multi-generational timescale to understand the influence of epigenetic modifiers on the genome of a species, much less the human species, whose timescale is orders of magnitude beyond animal models used to establish much of the risk/benefit data used in pre-approval evaluations. RNAi interference technology promises specificity — one RNAi molecule change equals one gene suppressed — but ignores the virtually infinite possibility of unintended, adverse effects in what are incomprehensibly complex biological systems. Indeed, researchers have warned that RNAi can not only profoundly affect gene expression, but that the changes it induces can permanently alter a species through inherited traits 1:

“Once a silencing effect is initiated, the effect may be inherited. The biochemistry of this process varies depending on the organism and remains an area of active research with many unknown aspects. Nevertheless, it is known for example that human cells can maintain the modifications necessary for TGS, creating actual or potential epigenetic inheritance within tissues and organisms (Hawkins et al., 2009). In some cases the dsRNA pathways induce RNA-dependent DNA methylation and chromatin changes (TGS) that persist through reproduction or cell division, and in other cases the cytoplasmic pathways remain active in descendents (Cogoni and Macino, 2000).”

GM Technology and Unintended Consequences

Indeed, critics of RNA interference technology make the point that RNAi technology aims to target the production of a specific protein by identifying the sequence in question. But two or more genes can have sequence homologies. This means, as applies to the use of RNA interference in medicine, a gene that is targeted to turn off a “disease-causing gene” could have a number of off-target effects, one of which w

Criticisms of RNAi in the agricultural sector are long-standing among the highly informed. For instance, Jonathan Latham, Ph.D. and Allison Wilson, Ph.D., wrote a seminal paper on the topic over a decade ago titled “Off-target effects of plant transgenic RNAi: three mechanisms lead to distinct toxicological and environmental hazards,” wherein 3 of the primary safety concerns are addressed: 1) Off target effects leading to non-specific down-regulation of plant RNAs 2) Off target effects affecting non-target invertebrates feeding on plant material 3) potential effects on mammals. In mammals, long (>30 bp) perfectly duplexed RNAs (such as are typically produced by plant RNAi transgenes) are Pathogen Associated Molecular Patterns (PAMPS) and are consequently highly potent triggers of innate anti-viral defences. The effects of long dsRNAs on mammalian cellular functions are typically profound and extend to complete inhibition of protein translation and cell death. Nevertheless, the implications of such molecules in  the mammalian diet have hardly been tested.

That’s quite a serious list of concerns. As you can see, concern #3 includes the possibility that these dsRNAs may lead to protein translation and cell death. Clearly if the EPA has declared Monsanto and Dow’s new RNAi corn safe for human consumption, they would need to prove this a non-issue.

Monsanto Falling On Their Own ‘Peer-Reviewed’ Sword

Surprisingly, Monsanto itself has produced one of the most damning papers on the topic yet. Several years ago I stumbled upon a study funded by Monsanto that raised a number of red flags for me. Titled, “Endogenous small RNAs in grain: Semi-quantification and sequence homology to human and animal genes,” researchers employed by Monsanto in their St. Louis, MO, laboratory analyzed the presence of endogenous small RNAs in common food and feed staples — soybeans, corn, rice — discovering that hundreds of these plant RNAs had a perfect 100% complementary match to human genes as well as other mammals.

Why is this significant? Endogenous small RNAs, such as small interfering RNAs (siRNAs) and microRNAs (miRNAs), are effector molecules of RNA interference (RNAi), which is a gene suppression mechanism found in plants, mammals, and other eukaryotes. The implication, therefore, of Monsanto’s finding is that plant RNAs — were they capable of surviving digestion and accumulating in target tissues to physiologically relevant concentrations — are capable of epigenetically silencing hundreds of genes within the human body. Below you will find a list of the RNA/gene matches between rice and the human genome:

Despite the abundance of perfect 100% complementarity matches listed above, Monsanto’s conclusion was a conveniently pollyannish dismissal of the safety implications of these findings, stating that:

“The abundance of endogenous small RNA molecules in grain from safely consumed food and feed crops such as soybean, corn, and rice and the homology of a number of these dietary small RNAs to human and animal genomes and transcriptomes establishes a history of safe consumption for dietary small RNAs.” 

While this may be true for traditionally used plants, it does not follow that genetically modified organisms would necessarily be safe because non-GMO versions are. [The pseudo-scientific conceptual ploy of “substantial equivalency behind traditional and GMO cultivars has been the basis for the approval of GMOs since their inception.] Monsanto’s conclusion relates to the fact that it has invested a great amount of resources into developing proprietary RNAi-based organisms which help it to maintain and further expand its monopolizing control on the global food supply.

Additionally, one of their primary justifications for concluding the safety of endogenous plant RNAs on human health was that: “…there does not appear to be any evidence in the scientific literature suggesting that intact RNA is absorbed following ingestion.” This bold claim has been disproven. The Monsanto paper was written in 2008, 3 years before the groundbreaking discovery of Zhang et al published in the Cell Research, entitled,”Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA,” wherein it was demonstrated that human subjects fed rice containing the microRNA MIR168a have measurable amounts of it present in their blood and tissue, and that it binds to the lipoprotein receptor adapter protein in the liver. More succinctly:

“These findings demonstrate that exogenous plant miRNAs in food can regulate the expression of target genes in mammals.”

Since then, a hotly contested debate has ensued, which is understandable, given the increasingly politicized and financially-motivated nature of scientific debate and findings.

Here’s Monsanto’s conclusion about the safety of RNAi-based food technology:

“Based on this evidence it can be concluded that RNAi-mediated regulation of gene expression in biotechnology-derived crops is as safe for food and feed use as conventional crops that harness RNAi-based gene regulation as one of several ways to achieve new plant traits. The safety of future crops generated through applications of RNAi should thus be evaluated for safety using the existing comparative safety assessment paradigm, which has been developed for biotechnology-derived Crops.”

First of all, the “evidence” they are referring to is based on an axiomatic absurdity: equating the absence of evidence with evidence of absence. In other words, you can’t prove this negative: “that a hazard does not exist” because positivistic proof of anything requires that you demonstrating something, not nothing.

Let’s also not overlook the conflict of interest statement at the end of their paper: “All authors are employees of the Monsanto Company. The  Monsanto Company is an agricultural company that produces,” which speaks to Monsanto’s long history of funding science that denies safety risks of their products, such as the Roundup-Cancer link, which now even the California EPA accepts as fact.

The Heart of the Problem

In a seminal paper published in 2016 in Trends in Microbiology, entitled, “How Our Other Genome Controls Our Epi-Genome,” it is proposed that the very RNAs biotech/agrochemical companies like Monsanto and Dow are tinkering with in our food should be reconsidered as part of the definition of our species versus the conventional view that it is just something informationally inert that we eat and exists “out there.” Using a revised version of Da Vinci’s Vitruvian man, as pictured below, they propose that there are 4 inseparable parts of our species: 1) human cells 2) human microbiota and other bacteria 3) Fungi and Viruses 4) Food.

As you can see, because of the interconnectivity and “social networking” functionalities of RNAs packaged in microvesicles called exosomes, all four parts of this new definition of man become united in an indivisible whole. Because these RNAs packed in edible exosomesepigenetically active, the food we eat “literally talks to our mRNA and DNA,” as I have explained in greater detail here:  “Amazing Food Science Discovery: Edible Plants ‘Talk’ To Animal Cells, Promote Healing.”

As we have seen in Monsanto’s own paper on the topic, foods contain hundreds of small RNAs whose 100% complementarity match with human genes imply they can directly impact, and even silence those genes. This silencing is not necessarily “bad,” but it is clear that we are tinkering with a design that we are only just beginning to understand, much less know how to ascertain the risks of and properly regulate. But, considering that Monsanto’s research reveals how intricately connected the human and the food genomes are are — and furthermore, that post-2008 research has surfaced showing Monsanto was wrong and plant RNAs from food do have direct impacts on human genome/epigenome expression — it is highly irresponsible for them to continue to claim that food manipulation technologies will not have unintended, adverse effects in principle. Sadly, with the EPAs approval of four new RNAi forms of corn already completed, and likely many more on the way, we may be stuck with secondary and much slower forms of recourse: post-marketing, epidemiological surveillance of exposed populations, where patterns of disease can take decades if not generations to surface — and then with so many confounding factors at play, not with any certainty.

That said, I believe education and the awareness it generates is our best bet at countermanding the widespread acceptance of this highly experimental and obviously dangerous form of genetic engineering. As has been the case recently with glyphosate being classified as a carcinogen by the California EPA, and a growing mainstream movement to fight the forced feeding of non-labeled GMO laden products (March Against Monsanto), the tides are turning. Please help us spread this information far and wide.

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*This work is reproduced and distributed with permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here: http://www.greenmedinfo.com/greenmed/newsletter

References

Heinemann JA, Agapito-Tenfen SZ, Carman JA. A comparative evaluation of the regulation of GM crops or products containing dsRNA and suggested improvements to risk assessments. Environ Int. 2013 May;55:43-55. doi: 10.1016/j.envint.2013.02.010. Epub 2013 Mar 20. PubMed PMID: 23523853.

 

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10 Things That Happen To Your Body When You Walk Everyday

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In Brief

  • The Facts:

    There are multiple health benefits to be gained by taking a simple walk every day. These benefits are measurable, and if you don't already have an active lifestyle it can be a great way to assist you with your health.

  • Reflect On:

    Reflect on how the human race has become extremely sedentary, and how disease rates continue to climb as a result of the modern human lifestyle.

The human experience has become extremely sedentary, the average human lifestyle in the western world has been linked to multiple diseases and is one of the main causes of why disease rates continue to climb, among many other factors that surround all aspects of human life, like big food, for example. With technology in place and jobs that require tremendous amounts of sitting, there is no doubt that it’s having a detrimental effect on our lives.

That being said, the world is clearly becoming way more health conscious. It’s like we needed this experience of unhealthy food, the corporate take-over of everything, and our motionless lifestyle to knock us out of it. We are seeing a health revolution take place, where more and more people are becoming health conscious, and are always being encouraged to be more active.

Ultimately, we can’t really blame the human experience for our lack of movement, it’s something that all of us have the time to incorporate into our lives in one way or another, and if you’re someone who doesn’t enjoy being too active, a simple walk every day can have tremendous amounts of benefits. As pointed out in the video below, by Bright Side.

If You Want To Increase The Benefits Even More, Walk Barefoot

It’s called grounding, or ‘earthing’ and it involves placing your feet directly on the ground, without shoes or socks as a barrier. Why? Because there is an intense negative charge carried by the Earth, it’s electron-rich, which serves as a good supply of antioxidants and free radical destroying electrons.

A study published in the Journal of Environmental and Public Health titled “Earthing: Health Implications of Reconnecting the Human Body to the Earth’s Surface Electrons” postulates that earthing could represent a potential treatment for a variety of chronic degenerative diseases.

That’s right, many positive health benefits occur as a result of walking barefoot, and these are measurable.

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The picture below represents improved facial circulation (right image) after 20 minutes of grounding, as documented by a Speckle Contrast Laser Imager (dark blue=lowest circulation; dark red=highest circulation). Image Source: Scientific Research Publishing

If you want to read more publications and access the in-depth science with regards to grounding, you can refer to the article linked above the picture.

10 Things That Happen To Your Body When You Walk Barefoot On Earth 

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So far, the response to this interview has been off the charts as people are calling it the most concise update of what's happening in our world today.

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Nature Valley Ad Shows The Down Side Of Children Addicted To Technology

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In Brief

  • The Facts:

    Technology has impacted most of our lives in a really big way. We use it daily for everything we do pretty much. Kids today, unlike previous generations, use technology more than ever and spend much less time in nature.

  • Reflect On:

    How much is too much technology for young and developing minds? Is it time to reevaluate our children's relationship with technology and get them back into nature?

Technology has become a staple in most of our lives, really, could you imagine life without it? In the video posted below, Nature Valley asks 3 generations what it was that they did for fun as a kid, the answers from the youngest generation may or may not surprise you, but is it time to cut back on the technology and bring kids back to nature?

Technology is not bad per se, that isn’t the discussion here. This is about how we use it.

Before technology, children would look to nature for entertainment. They would play outside on the lawn, go sledding, build forts, and use their imagination to create their own entertainment. Nowadays it’s all too easy for kids to get sucked into technology, there are video games, tablets, computers, cell phones and television, all of which provide a type of escape from the real world. Although, there are many ways that technology is and has been used for good in the world, is the disconnect that it is causing children and adults to part from nature causing more harm?

With the rise of mental disorders and illnesses, is it possible that the answer to these issues is simply to get kids back into nature, more time with self, using their brains to build things, be creative and connect to the energy from the Earth? We already know how effective a simple walk or hike in nature is and how they both can literally change our brains. Nature appears to be much more important than we generally give it credit for.

In my own experience, disconnecting from technology and going camping on my own proved to be a very cathartic and healing experience for me. I’ve come to realize that although being immersed in nature regularly does have a lot of benefits, but even just making time for it at all can cause a positive impact. For many of us who live in cities, with the constant bombardment of noise and of course EMF frequencies etc., just disconnecting for a short period can make a huge difference.

The following video is a brilliant ad from Nature Valley, check it out.

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It’s easy to get emotional watching something like this as it shows just how far removed the newer generations are from what has been most natural to children for centuries, simply playing in nature. The children are essentially self-proclaimed tech addicts and get their entertainment by playing video games, watching videos or tv shows, texting etc. Is it time to go back to the basics and start evaluating how detrimental too much technology can be on young and developing brains? You can read more about this issue here, Is Your Child Struggling From Nature-Deficit Disorder?

Is it up to the parents to ensure they are setting proper boundaries with the amount of time their children are allowed to use technology? Or is this the future and something we should simply let happen as a natural part of evolution?

Much Love

Free David Wilcock Screening: Disclosure & The Fall of the Cabal

We interviewed David about what is happening within the cabal and disclosure. He shared some incredible insight that is insanely relevant to today.

So far, the response to this interview has been off the charts as people are calling it the most concise update of what's happening in our world today.

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6 Proven Ways to Cleanse Your Liver & Release Pent Up Anger

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In Brief

  • The Facts:

    In Chinese Medicine our liver is directly connected to anger and unfortunately, we live in a world where our liver is regularly taxed by toxic chemicals. Thankfully there is plenty that you can do without medication to keep this vital organ healthy!

  • Reflect On:

    What toxins are you regularly exposed to and what steps are you currently taking to combat them?

A toxic liver can lead to anger. In Chinese medicine, our biggest detox organ – our liver – is the organ connected to anger. When we work at changing our lifestyles and daily habits, we begin to see it having a positive effect on our mood as well as general health.

When toxicity mounts we have a more difficult time controlling or letting go of our angry feelings. Toxic chemicals accumulate in our bodies because we live in a toxic world. We microwave in plastic, we cook food in Tephlon coated pans, we smoke, we take medication, and eat fried and processed foods.

These food-like products contain toxic chemical preservatives, glyphosate; GMOs and pesticides. Ingesting poison daily results in everything from immune deficiency, mood disorders, lowered mental performance, and even life-threatening cancer.

So, besides avoiding many of the contributors of liver toxicity – what can we do?

1. Eat less added sugar & address possible yeast overgrowth in the gut

Yeast can cause fermentation of food in place of digestion and cause bloating and gas. It can contribute to “leaky gut syndrome” – thus in turn can lead to the production of toxins that may affect the brain and nervous system. Yeast overgrowth can produce alcohol as its byproduct, acetaldehyde, giving us a “hangover” feeling. It can also lead to liver damage, and it prevents the proper detoxification of other pollutants, increasing the toxicity of other toxins.

2. Support the liver with botanicals

Plant medicine like Milk Thistle and Dandelion Root can help cleanse the liver. Both extracts are known to be pretty safe and well tolerated, and toxic or adverse effects observed in the reviewed clinical trials seem to be minimal. Only those with a ragweed, iodine or latex allergy should be cautious with dandelion. (Learn more about milk thistle)

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3. Drink organic aloe vera juice

High quality; raw organic aloe vera can be a phenomenal digestive aid. It seals the gut wall, aids in digestion, has anti-inflammatory properties, helps the immune system, and detoxifies the liver, skin, and colon.

4. Cook with more turmeric & black pepper to help the body absorb nutrients better

Black pepper contains a compound called piperine, which increases the bioavailability of food by decreasing activity in the intestinal tract and inhibiting the metabolism of certain enzymes. Better still, cook with lots of turmeric and black pepper together. The combination helps the body absorb more curcumin, the active ingredient in turmeric.

This ingredient can heal gut wall permeability due to its amazing anti-inflammatory properties. It also aids in digestion, strengthens the immune system, improves asthma, heals wounds, prevents the progression of memory loss, controls diabetes, improves liver function, lowers cholesterol, and fights cancer. (Note: A great supplement for this that I recommend for is Liver Health)

5. Incorporate liver cleansing foods into your diet

Incorporate liver cleansing foods such as green leafy veggies, avocados, apples, garlic, olive oil, citrus fruit, beets, and cruciferous vegetables into your weekly diet.

6. See An Acupuncturist

Used for thousands of years, acupuncture has been used to detox and balance the liver meridians to reduce anger and other emotional and psychiatric issues.  Simple needless acupressure is often used on children.


Learn more about my family’s healing journey (including everything that has worked for me and many of my clients) in my book Healing Without Hurting. And to receive more info on how you and your family can overcome ADHD, apraxia, anxiety and more without medication SIGN UP HERE.

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