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Magnesium: The Safe First Line of Defense for Clinical Depression

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This article was written by Ali Le Vere for Greenmedinfo.com. It’s republished here with their permission. For more information from Greenmedinfo, you can sign up for the newsletter here.

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The science supporting the efficacy of magnesium for major depression and other psychiatric disorders, testing for magnesium deficiency, and which forms and dosages are most effective.

Depression, a life-threatening psychiatric disorder, lies at the confluence of biochemical, hormonal, immunological, and neurodegenerative variables, which intersect to generate the pro-inflammatory state with which depression is associated. A major public health issue, depression is estimated to become one of the top three contributors to the global burden of diseases within a few years. Not only does depression consume a sizable portion of health care expenditures, but it is considered to be an independent risk factor for metabolic, cardiovascular, and neuropsychiatric disorders (1).

Current treatments are predicated upon a misguided serotonin theory of depression, and are accompanied by a laundry list of deleterious side effects ranging from sexual dysfunction to homicidality (2, 3, 4). Antidepressant medications likewise significantly increase the risk of all-cause mortality, or death from any cause, as well as heart disease, leading researchers to deem this class of pharmaceuticals as harmful to the general population (5). This, in combination with data indicating that antidepressants are clinically equivalent to placebo, render them an unfavorable option (6), especially considering that they offer little in the way of resolving the root cause.

Magnesium: The Miracle Mineral

Rather than resorting to psychotropic drugs, it would be prudent to explore whether magnesium (Mg) supplementation improves depression, since this essential mineral is implicated in the pathophysiology of this disorder. Magnesium may be indeed branded as miraculous given its essentiality as a cofactor to over three hundred enzymatic reactions (7). It is second only to potassium in terms of the predominant intracellular cations, or ions residing in cells that harbor a positive charge (7).

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Magnesium is fundamentally involved in protein production, synthesis of nucleic acids, cell growth and division, and maintenance of the delicate electrolyte composition of our cells (7). It also imparts stability to the membranes of the energy factories of our cells called mitochondria (7). As articulated by researchers, “The physiological consequences of these biochemical activities include Mg’s central roles in the control of neuronal activity, cardiac excitability, neuromuscular transmission, muscular contraction, vasomotor tone, and blood pressure” (7).

The biological effects of magnesium are widespread. When deficient, magnesium is correlated with systemic inflammation. Not only does magnesium sufficiency promote cardiovascular health, relaxing the smooth muscles that comprise blood vessels and preventing high levels of vascular resistance that cause hypertension, but it also plays a role in musculoskeletal health and prevents sarcopenia, osteoporosis, and fractures (8). Magnesium is essential to regulation of sleep (9) and vitamin D metabolism (10) as well as neural plasticity and cognitive function.

However, food processing and industrial agriculture, including monoculture crop practices and the use of magnesium-devoid fertilizers, have led to soil erosion and depletion of magnesium content in our food (7). Magnesium is likewise removed from most drinking water supplies, rendering magnesium deficiency an inevitability (11). As such, our daily intake of magnesium has steadily declined from 500 milligrams (mg) per day to 175 mg per day (7). The nutrient-poor, energy-dense dietary patterns which have come to dominate the industrialized landscape are also insufficient in the fiber-rich fruits and vegetables which contain magnesium.

Animal Studies Propose a Role for Magnesium in Depression

Preliminary animal studies pointed to a role of magnesium in depression, as depletion of magnesium in the diet of mice lead to enhanced depression- and anxiety-related behavior such as increased immobility time in the forced swim test (12). In the forced swim test, a common assay for examining depression-like behavior in rodents, the animal is confined to a container filled with water and observed as it attempts to escape. The time in which the animal exhibits immobility is used as a barometer of despair, indicating that the animal has succumbed to a fate of drowning (1).

This model is confirmed by studies showing that administering substances with antidepressant properties such as Hypericum perforatum, also known as St. John’s Wort, can significantly decrease the time the animal spends without locomotor activity (12). In addition, the time the animal spends immobilized is influenced by many of the factors that are changed as a consequence of depression in humans, such as drug-withdrawal-induced anhedonia, impaired sleep, and altered food consumption (1).

Human Studies Confirm the Role of Magnesium in Depression

There is a paucity of research on the influence of specific micronutrients in depression and results are inconsistent, but several studies have revealed low serum magnesium in this mood disorder. It is well-documented, for example, that dietary magnesium deficiency in conjunction with stress can lead to neuropathologies and symptoms of psychiatric disorders. Researchers echo this sentiment, stating that, “Dietary deficiencies of magnesium, coupled with excess calcium and stress may cause many cases of other related symptoms including agitation, anxiety, irritability, confusion, asthenia, sleeplessness, headache, delirium, hallucinations and hyperexcitability” (11, p. 362).

The Hordaland Health study in Western Norway illustrated an inverse association between standardized energy-adjusted magnesium intake and depression scores, meaning that people who consumed less magnesium had higher rates of depression (13). When the serum and cerebrospinal fluid of acutely depressed patients diagnosed with major depressive disorder or bipolar patients in a depressive episode were compared to healthy controls, the calcium to magnesium ratio was found to be elevated in the former (14). Calcium and magnesium are minerals which antagonize one another and compete for absorption, since each of these minerals is a divalent cation (a positive ion with a valence of two). Suicidality, one of the primary manifestations of severe depression, is accompanied by low cerebrospinal fluid levels of magnesium despite normal calcium levels, lending credence to the role of magnesium in positive emotionality (15).

Magnesium Effective in Bipolar Disorder, Fibromyalgia, PMS, and Chronic Fatigue Syndrome

A formulation of magnesium aspartate hydrochloride known as Magnesiocard has been shown to invoke mood-stabilizing effects in patients with severe rapid cycling bipolar disorder in one open study label (16). In half of the patients treated, this magnesium preparation had results equivalent to lithium, the standard of care for this patient population, such that the researchers suggested: “The possibility that Magnesiocard could replace or improve the efficacy of lithium as a preventive treatment of manic-depressive illness merits further clinical investigation” (16, p. 171). When used as an adjunctive therapy in severe, therapy-resistant mania, magnesium sulphate infusions significantly reduced the use of lithium, benzodiazepines and neuroleptics, so much so that the researchers concluded that it “may be a useful supplementary therapy for the clinical management of severe manic agitation” (17, p. 239).

In another randomized trial of elderly patients with type 2 diabetes and magnesium deficiency, elemental magnesium administered at 450 mg per day was found to have equivalent efficacy to 50 mg of the antidepressant drug Imipramine in treating depressive symptoms (18). Magnesium citrate taken at 300 mg per day has likewise been shown to decrease depression and other symptoms in patients with fibromyalgia as indicated by significant decreases in the fibromyalgia impact questionnaire (FIQ) and Beck depression scores (19).

Data also indicate that supplementation with 360 mg of magnesium administered to women with premenstrual syndrome (PMS) three times a day in the second half of the cycle is effective for so-called negative affect and other premenstrual-related mood symptoms (20). Lastly, intramuscular magnesium sulphate administered every week for six weeks has been proven to be effective in improving emotional state and other parameters in chronic fatigue syndrome (CFS) (21).

Mechanism of Action for Antidepressant Effects of Magnesium

According to researchers, “Biological systems discussed to be involved in the pathophysiology of affective disorders and the action of mood stabilizing drugs are affected by Mg, such as the activity of the hypothalamus–pituitary–adrenocortical (HPA) system, corticotropin releasing factor (CRF)-, GABA- and glutamatergic (via NMDA receptors) neurotransmission and several transduction pathways including protein kinase C” (12). Not only that, but magnesium elicits similar effects on nocturnal hormonal secretion and sleep brain waves to lithium salts, which are used as a treatment modality for bipolar disorder, supporting the role of magnesium as a mood stabilizer (22).

Magnesium operates as an agonist, or a stimulatory molecule, for γ-aminobutyric acid (GABA) receptors (22). GABA is the main inhibitory neurotransmitter in the central nervous system. By binding to the GABA receptor and replicating the effects of GABA, magnesium may alleviate anxiety. Magnesium may also elicit its antidepressant effects by acting as an inorganic antagonist of N-methyl-d-aspartic acid (NMDA) receptor function (Poleszak et al., 2007). Receptor antagonists are ligands, or substances, which bind to a receptor but inhibit its activity rather than activating it. NMDA receptors, which occur on the surface of nerve cells, are activated in part by glutamate, one of the excitatory amino acids in the brain.

Researchers state that, “Dysfunction of NMDA receptors seems to play a crucial role in the neurobiology of disorders such as Parkinson’s diseaseAlzheimer’s diseaseepilepsy, ischemic stroke, anxiety and depression,” such that, “ligands interacting with different sites of NMDA receptor complex are widely investigated as potential agents for the treatment of a variety of neuropsychiatric disorders” (22). In fact, drug inhibitors at the NMDA receptor complex, such as ketamine, demonstrate antidepressant effects (23, 24), but also induce such severe side effects that their clinical utility is limited (31). Magnesium, on the other hand, may have a similar mechanism of action by interfering with NMDA receptor activation without the adverse consequences of drug-induced NMDA receptor blockade (25).

Recent Study Proves Efficacy of Oral Magnesium for Depression

A recent open-label, randomized, cross-over trial was conducted in outpatient primary care clinics on 126 adults diagnosed with depression (26). During the intervention, 248 mg of elemental magnesium chloride per day, obtained from four 500 mg tablets, was administered for six weeks and compared to six weeks of no treatment, and subjects were evaluated for changes in depressive symptoms (26).

Magnesium administration results in clinically significant improvements in scores on both the Patient Health Questionnaire-9 (PHQ-9), a validated measure of the severity of depression and response to treatment, as well as the Generalized Anxiety Disorders-7 (GAD-7), a sensitive self-reported screening tool for severity of anxiety disorders (26). Impressively, results appeared in as little as two weeks, representing the dramatic improvement that nutrient restoration can facilitate (26). Impressively, however, magnesium exerted anti-depressant effects regardless of baseline magnesium level. It also exhibited efficacy independent of the gender, age, or baseline severity of depression of subjects, as well as their use of antidepressant medications (26). The authors of the study conclude, “Magnesium is effective for mild-to-moderate depression in adults. It works quickly and is well tolerated without the need for close monitoring for toxicity” (26).

Populations At Risk for Magnesium Deficiency

Half of the population of the United States was found to consume less than the recommended amount of magnesium when estimated a decade ago (27). Not only is magnesium lost with certain medical conditions, but this mineral is excreted as a consequence of biological activities such as sweating, urinating, and defecating as well as excess production of stress hormones (7, 11). In addition, because low magnesium has been correlated with various disease states, increasing magnesium status may mitigate risk of these diseases.

For instance, researchers note that, “Low magnesium intakes and blood levels have been associated with type 2 diabetes, metabolic syndrome, elevated C-reactive protein, hypertension, atherosclerotic vascular disease, sudden cardiac death, osteoporosis, migraine headache, asthma, and colon cancer” (27, p. 153). In addition, magnesium deficiency at a cellular level “elicits calcium-activated inflammatory cascades independent of injury or pathogens” (27, p. 153). Low magnesium is associated with systemic inflammation, and inflammation is at the root of most chronic and degenerative diseases.

Testing for Magnesium and Food Sources of Magnesium

While the first inclination of some physicians may be to test magnesium levels for an objective parameter of deficiency, the widely used serum or plasma magnesium does not accurately reflect magnesium levels stored in other tissues (28, 29). In addition, both this hematological index of magnesium status, referred to as total magnesium, and the erythrocyte magnesium level, indicative of the levels of magnesium inside red blood cells, are not negatively affected until severe magnesium deprivation has occurred (7). Therefore, these testing methodologies are not accurate enough to catch preliminary or subclinical magnesium deficiency.

Good food sources of magnesium include pumpkin and squash seed kernels, Brazil nuts, almonds, cashews, peanuts, pine nuts, quinoa, spinach, Swiss chard, beet greens, potatoes, artichoke hearts, dates, bananas, coconut milk, prickly pear, black beans, lima beans, soybeans, and seafood sources including halibut, abalone, anchovy, caviar, conch, crab, oyster, scallop, snail, and pollock. However, it is important to note that magnesium can be leeched from vegetables when food is boiled, and that fiber in excess can decrease magnesium absorption by increasing gastrointestinal motility (7).

Most Bioavailable Forms of Magnesium

As elucidated by the researchers, “Over-the-counter magnesium can be offered as an alternative therapy to those patients hesitant to begin antidepressant treatment and is easily accessible without a prescription” (26). Because the soil is no longer enriched in magnesium, supplementation may be warranted. Organic salts of magnesium, including the acetate, ascorbate, aspartate, bicitrate, gluconate, and lactate forms are more soluble and biologically active over the magnesium mineral salts such as magnesium oxide, magnesium carbonate, magnesium chloride, and magnesium sulfate (7).

However, case studies have shown remarkably rapid recovery from major depression, in less than seven days, when magnesium glycinate and magnesium taurinate are administered at dosages of 125 to 300 mg with each meal and at bedtime (11). Magnesium threonate may also be explored as a therapeutic option, as it may have better penetrance of the blood brain barrier and restore neurological levels of magnesium. This form, which is delivered directly to the brain, may improve cerebral signaling pathways and synaptic connections between nerve cells as well as support learning and memory, although the studies have been conducted in animal models (30).

Researchers report that magnesium is usually effective for treating depression in general use, and that comorbid conditions occurring in these case studies, including “traumatic brain injury, headache, suicidal ideation, anxiety, irritability, insomnia, postpartum depression, cocaine, alcohol and tobacco abuse, hypersensitivity to calcium, short-term memory loss and IQ loss were also benefited” by magnesium supplementation (11, p. 362). Barring abnormal kidney function, the Institute of Medicine sets the upper tolerable limit for intake at 350 mg of elemental magnesium per day, but there are few adverse side effects documented unless consumed in inordinate doses (26).

Before changing your medication or nutraceutical regimen, always consult a functional or integrative medical doctor for contraindications. However, given the benign nature of magnesium supplementation and the ubiquity of magnesium insufficiency, depressedpatients should be offered this as a first line strategy alongside a holistic root-cause resolution approach to treating depression (26).

For additional research on magnesium, visit our database on the subject. 

References

1. Yankelevitch-Yahav, R. et al. (2015). The Forced Swim Test as a Model of Depressive-like Behavior. Journal of Visualized Experiments,  97, 52587.

2. Srilakshmi, P., & Versi, L. (2012). Review of sexual dysfunction due to selective serotonin repute inhibitors. AP Journal of Psychological Medicine, 13(1), 28-31.

3. Dording, C.M. et al. (2002). The pharmacologic management of SSRI-induced side effects: a survey of psychiatrists. Annals of Clinical Psychiatry, 14(3), 143-147.

4. Moore, T.J., Glenmullen, J., & Furberg, C.D. (2010). Prescription drugs associated with reports of violence towards others. PLoS One, 5, e15337.

5. Maslej, M.M. et al. (2017). The Mortality and Myocardial Effects of Antidepressants Are Moderated by Preexisting Cardiovascular Disease: A Meta-Analysis. Psychotherapy and Psychosomatics, 86, 268-282.

6. Antonuccio, D.O., Burns, D.D., & Danton, W.G. (2002). Antidepressants: A Triumph of Marketing Over Science? Prevention & Treatment, Volume 5(25).

7. Newhouse, I., & Finstad, E.W. (2000). The Effects of Magnesium Supplementation on Exercise Performance. Journal of Sports Medicine, 10(3), 195-200.

8. Welch, A.A., Skinner, J., & Hickson, M. (2017). Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort. Nutrients, 9(11), E1189. doi: 10.3390/nu9111189.

9. Abbasi, B. et al. (2012). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of Research in Medical Science, 17(12), 1161-1169.

10. Mursu, J. et al. (2015). The association between serum 25-hydroxyvitamin D3 concentration and risk of disease death in men: modification by magnesium intake. European Journal of Epidemiology, 30(4), 343-347.  doi: 10.1007/s10654-015-0006-9.

11. Eby, G.A., & Eby, K.L. (2006). Rapid recovery from major depression using magnesium treatment. Medical Hypotheses, 67(2), 362-370.

12. Singewald, N. et al. (2004). Magnesium-deficient diet alters depression- and anxiety-related behavior in mice–influence of desipramine and Hypericum perforatum extract. Neuropharmacology, 47(8), 1189-1197.

13. Jacka, F.N. et al. (2009). Association between magnesium intake and depression and anxiety in community-dwelling adults: the Hordaland Health Study. Australian and New Zealand Journal of Psychiatry, 43(1), 45-52. doi: 10.1080/00048670802534408.

14. Levine, J. et al. (1999). High serum and cerebrospinal fluid Ca/Mg ratio in recently hospitalized acutely depressed patients. Neuropsychobiology, 39(2), 63-70.

15. Banki, C.M. et al. (1995). Cerebrospinal fluid magnesium and calcium related to amine metabolites, diagnosis, and suicide attempts. Biological Psychiatry, 20, 163-171.

16. Chouinard, D. et al. (1990). A pilot study of magnesium aspartate hydrochloride (Magnesiocard) as a mood stabilizer for rapid cycling bipolar affective disorder patients. Progress in Neuro-Psychopharmacology, Biology, and Psychiatry, 14, 171-180.

17. Heiden, A. et al. (1999). Treatment of severe mania with intravenous magnesium sulphate as a supplementary therapy. Psychiatry Research, 3, 239-246.

18. Barragán-Rodríguez, L., Rodríguez-Morán, M., & Guerrero-Romero, F. (2008). Efficacy and safety of oral magnesium supplementation in the treatment of depression in the elderly with type 2 diabetes: a randomized, equivalent trial. Magnesium Research, 21(4), 218-223.

19. Bagis, S. et al. (2013). Is magnesium citrate treatment effective on pain, clinical parameters and functional status in patients with fibromyalgia? Rheumatology International, 33(1), 167-172. doi: 10.1007/s00296-011-2334-8.

20. Facchinetti, F. et al. (1991). Oral magnesium successfully relieves premenstrual mood changes. Obstetrics and Gynecology, 78(2), 177-181.

21. Cox, I.M. et al. (1991). Red blood cell magnesium and chronic fatigue syndrome. The Lancet, 337(8744), 757-760.

22. Held, K. et al. (2002). Oral Mg(2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans. Pharmacopsychiatry, 35(4), 135-143.

23. Zarate, C.A. Jr. et al. (2006). A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Archives of General Psychiatry, 63, 856-864.

24. Berman, R.M. et al. (2000). Antidepressant effect of ketamine in depressed patients. Biological Psychiatry, 47, 351-354.

25. Poleszak, E. et al. (2007). NMDA/glutamate mechanism of antidepressant-like action of magnesium in forced swim test in mice. Elsevier Pharmacology Biochemistry and Behavior, 88(2).

26. Tarleton, E.K. et al. (2017). Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PLoS One, 12(6), e0180067. doi: 10.1371/journal.pone.0180067.

27. Rosanoff, A., Weaver, C.M., & Rude, R.K. (2012). Suboptimal magnesium status in the United States: are the health consequences underestimated? Nutrition Reviews, 70(3), 153-164. doi: 10.1111/j.1753-4887.2011.00465.x.

28. Altura, B.T. et al. (1994). Characterization of a new ion selective electrode for ionized magnesium in whole blood, plasma, serum, and aqueous samples. Scandinavian Journal of Clinical Lab Investigations, 54(Suppl. 217), 21–36.

29. Weller, E. et al. (1998). Lack of effect of oral Mg-supplementation on Mg in serum, blood cells and calf muscle. Medical Science Sports Exercise, 30, 1584–1591.

30. Slutsky, I. et al. (2010). Enhancement of learning and memory by elevating brain magnesium. Neuron, 65(2), 165-177. doi: 10.1016/j.neuron.2009.12.026.

31. Willetts, J., Balster, R.L., & Leander, J.D. (1990). The behavioral pharmacology of NMDA receptor antagonists. Trends in Pharmacological Science, 11, 423-428.

Ali Le Vere holds dual Bachelor of Science degrees in Human Biology and Psychology, minors in Health Promotion and in Bioethics, Humanities, and Society, and is a Master of Science in Human Nutrition and Functional Medicine candidate. Having contended with chronic illness, her mission is to educate the public about the transformative potential of therapeutic nutrition and to disseminate information on evidence-based, empirically rooted holistic healing modalities. Read more at @empoweredautoimmune on Instagram and at www.EmpoweredAutoimmune.com: Science-based natural remedies for autoimmune disease, dysautonomia, Lyme disease, and other chronic, inflammatory illnesses.

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“I Tried Every Diet & Nothing Worked” How Mucus Free Living Saved This Woman’s Life

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In Brief

  • The Facts:

    After a year on a high-fat/high-protein lifestyle, Livia Macdonald nearly died. After adopting a 'mucus-free' lifestyle, a diet rich in fresh fruit and vegetables, she cured her depression, anxiety, and health issues.

  • Reflect On:

    True healing takes time and commitment, and a willingness to face the emotions and trauma buried beneath our eating habits.

In 2011, Livia Macdonald was looking for answers to her health. At nearly 300 lbs and stuck in the despairs of chronic illness, she was ready to make a big change. The first step—divorcing allopathic medicine all together. Like many others stepping away from conventional medicine, Livia found herself enveloped by the siren of holistic healthcare, adopting the protocols laid out by natural-health celebrity and functional medicine doctor, Mark Hyman.

Following Hyman’s vitality guidelines, Livia cut out grains, starches, and processed sugars, while incorporating more vegetables, ‘healthy’ fats and animal products into her diet.

I was told that high protein and high fats is the way to go because our brain needs fat. I even made my own ghee and ate loads of coconut oil and eggs every day,” she told Collective Evolution.

At first the high-fat diet did wonders for Livia’s health. She felt more energized, had more mental clarity, and even began to drop weight. “I lost almost 80 lbs the first year on the [high-fat] diet,” she said.

But after twelve months of a high-fat lifestyle, Livia said her body began to shut down.

“I started to feel awful. Like everything turned on me. I got severe depression, anxiety, shaking, internal tremors, my organs started to really hurt, I had them checked and my pancreas had so many fat deposits all over it and my cholesterol was through the roof after being optimal. My entire body started to shut down and I became bed ridden for an entire year.”

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During this difficult time Livia came across the work of Dr. Robert Morse, a regenerative detoxification specialist well known in the natural health world. One of the foundations of Dr. Morse’s teachings is that man is a part of the primate family, and therefore we are primarily a frugivore species whose bodies thrive off of fruit, some vegetables and herbs. Livia says that a lightbulb went off in her head immediately upon reading Dr. Morse’s work.

My intuition was screaming that this was the missing piece of my puzzle, and that he speaks the absolute truth.”

Arnold Ehret wrote “The Mucusless Diet Healing System,” a resource for the chronically ill. Ehret’s protocols implement systematic fasting, as well as a diet of raw fruit and vegetables.

Next, Livia discovered the work of a 19th century natural health educator named Arnold Ehret. Ehret’s rise to fame came through his in depth knowledge about the body, specifically in healing chronic disease through systematic fasting and a diet similar to what Morse prescribes—raw fruit and vegetables.

His magnum opus, The Mucusless Diet Healing System, detailed his many years working in a clinic for the chronically ill while implementing his detox protocols to cure their diseases. Ehret’s work garnered a cult-following throughout the early 20th century and inspired the works of well-known detox specialists like Robert Morse himself, Paul Braggs, and Alfredo Bowman.

Adopting A Mucus-Free Lifestyle

But Livia said her biggest aha moment did not come until she discovered the work of South-African detox specialist  Alexandra Cousins. Inspired by the teachings of Robert Morse and Arnold Ehret, Cousins takes their healing principles and merges them with the shamanic and emotional work which she feels is the missing piece for those seeking full-bodied healing.

What I am witnessing is that trauma, PTSD, OCD, addictions are running everyone’s lives,” she writes in her Facebook group, Living Mucus Free. “The degree will vary but we all have it unless we have specifically addressed it. It is safe to say that all my clients, especially the chronically ill suffer from some form of unresolved trauma. If you have adrenal, hormonal, thyroid, or CFS issues, you are dealing with trauma residue. Living mucus free tends to bring up all our unresolved trauma. As we no longer consume foods that numb us or stimulate us, trauma rises to the surface so that it can be felt and dealt with.”

Having endured years of ill-health herself and having tried almost every diet trend out there, Cousins eventually found solace through a lifestyle termed Living Mucus Free (LMF). Mucus, for those wondering, is the residue which builds in the body from eating non-species-specific food, i.e., animal products, grains, or most cooked food. This mucus putrefies and plaques to the intestinal walls, eventually causing acids to build up in the body and damage our organs and glands.

LMF does away with mucus-causing foods while utilizing fruit, vegetables, herbs, systematic fasting, lymphatic movement, and various trauma-release therapies. Today, Cousins teaches what she’s learned at detox retreats around the globe and inspires thousands through her fierce social media presence.

Alexandra Cousins; founder ‘Living Mucus Free’. Cousins teaches people how to heal their chronic illness through the principles of cellular detoxification.

Sweet potato pizza via Living Mucus Free.

Photo by Livia Macdonald.

Livia says she has dedicated herself to the Living Mucus Free principles with great results, incorporating daily intermittent fasting, herbal tinctures, movement and breathing practices targeted at draining the lymphatic system, as well as raw food diet.

“I have been vegan one year and living mucus free for 10 months now. My anxiety and depression cleared up within two months, never to return. I have so much more clarity and mental focus now and that is getting better with time, not worse. I am slowly healing my endocrine system and gaining more energy back, I am no longer bed ridden since the first couple of months on this lifestyle.. all my spiritual and emotional stuff has surfaced to be healed and it’s truly a fascinating and incredible journey to learn the truth and realize just how wrongly we have been conditioned in such a deep way.”

The emphasis in Living Mucus Free is elimination—getting out of the body’s way and allowing it to do its job of eliminating acids, toxins, undigested food material and mucoid plaque. This is primarily achieved through daily dry fasting and eating watery, astringent fruit, which pulls out toxins as it transits the digestive tract.

Another principle to the Living Mucus Free lifestyle is eating little to no fat while detoxing, a principle that goes against many of the high-fat diet trends of today. But as Alexandra Cousins explains, in the case of those who are cellularly degenerate, fats only serve to cover up their issues. Fats are anti-inflammatory, buffering the acidity in the body but never pulling the acids out. A temporary bandaid for true healing.

Livia feels this is what happened in her case, and it is why she thinks so many initially feel great adopting a high-fat diet.

“I feel the high fat diet works for some because it suppresses and clogs their lymphatic system so naturally they will feel instant relief. But now that I understand how the body actually works, of course you are going to show improvement at the beginning if you remove junk food, sugars/grains, dairy etc.”

Cousins also speaks much to the notion that fats, salts, animal products, and processed foods are stimulating to our nervous system which cover up our emotional wounds, so when we begin to remove these foods and focus on detoxifying the body, we are suddenly faced with old emotions or traumatic memories, and this, Alex says, is mostly what Living Mucus Free is about.

“When we detox on a cellular level, we are consistently clearing old information, old cellular memory in the form of emotion which is held in physical waste stored in the body, replacing it with new cellular information,” Alex Cousins, Living Mucus Free.

For those looking for a quick fix, Living Mucus Free probably isn’t the right fit. Those living the Mucus Free lifestyle don’t make false promises that you will be healed after a 30 day detox. The journey is slow and steady, one with bumps along the way known as healing crises. During a healing crisis any number of uncomfortable symptoms can arise as the body expels old debris and toxins. But as Livia says, walking through the discomfort is the only way towards true healing.

I believe that our society has everything so backwards,” says Livia. “We are taught to chase feeling good, and run away from feeling bad, and Living Mucus Free isn’t going to feel good in the beginning as it brings up our weaknesses for healing.”

The reward, as promised by Cousins, Morse, Ehret, and thousands of others who have healed through regenerative detox principles, is beyond anything we can imagine:

Unimaginable health and vitality, weight loss and reversed ageing, improved energy levels, mental clarity and confidence, liberation from anxiety, mood swings and self-doubt, resolution of stored trauma and a deeper connection to source, vastly improved sex life and orgasms.”

Is Living Mucus Free really the key to such incredible feats? The answer, it seems, is to be discovered only by those willing to walk through the fire to find out.

For more information about Living Mucus Free, visit Alexandra Cousins’ website, Living Mucus Free.

For amazing mucus free recipes and to continue following Livia’s journey, check her out Instagram or Facebook, or her website, LiveAlittleRaw.

Help Support Collective Evolution

The demand for Collective Evolution's content is bigger than ever, except ad agencies and social media keep cutting our revenues. This is making it hard for us to continue.

In order to stay truly independent, we need your help. We are not going to put up paywalls on this website, as we want to get our info out far and wide. For as little as $3 a month, you can help keep CE alive!

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Health

Measles Outbreaks: How a Witch Hunt Against Parents of Unvaccinated Children Was Unleashed

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In Brief

  • The Facts:

    Artilce written Vera Sharav, Children’s Health Defense Contributing Writer.

  • Reflect On:

    Why does the mainstream media label this as 'anti-vax' when it's just factual information? Why don't they ever address it or try to counter it?

We are witness to an orchestrated frenzy that has been revved-up by vaccine stakeholders – i.e., those who have a direct or indirect financial stake in vaccines– through the corporate / academic institutions that employ them. Their unified objective is to achieve maximum utilization of vaccines, and total compliance with vaccination schedules set by the government in collaboration with vaccine manufacturers.

During the measles outbreak in California in 2015, a large number of suspected cases occurred in recent vaccinees. Of the 194 measles virus sequences obtained in the United States in 2015, 73 were identified as vaccine sequences.

Contrary to the barrage of “fake news” promulgated by government public health officials and the media to influence public opinion, the fact is, most childhood infectious disease “outbreaks” include both vaccinated and unvaccinated children. What’s more, when the infection has been tested, vaccine strain has often been identified as the cause of infection.

In 2015, a “measles outbreak” in California’s Disney Land garnered nationwide front page publicity and dire warnings by public health officials and vaccine “authorities”. They generated high public anxiety. This fear mongering led to the demonization of unvaccinated children, who were perceived as the spreaders of disease.

Never disclosed to the public, but known to CDC officials is the following evidence that has finally been published in the Journal of Clinical Microbiology (2017):

“During the measles outbreak in California in 2015, a large number of suspected cases occurred in recent vaccinees. Of the 194 measles virus sequences obtained in the United States in 2015, 73 were identified as vaccine sequences (R. J. McNall, unpublished data).”[1]

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Rebecca J. McNall, a co-author of the published report, is a CDC official in the Division of Viral Diseases, who had the data proving that the measles outbreak was in part caused by the vaccine. It is evidence of the vaccine’s failure to provide immunity.

But this crucial information has been concealed, and continues to be withheld from the public.  After all, how many have read the belated disclosure in the Journal of Microbiology?

So, the mumps outbreak at Texas detention centers occurred following children’s MMR vaccination!  Does anyone fail to see the connection between vaccination and an infectious disease outbreak?

Current Mumps Outbreak Following Vaccination

The Texas Tribune headline announced: Nearly 200 People In Texas Detention Facilities Have Contracted Mumps, March 1 2019. Since October, 186 children and adults contracted mumps at migrant detention facilities across Texas, according to a state health agency. These include immigrants and employees.

Lara Anton, a spokeswoman for the Department of State Health Services, said in an email that patients range in age from 13-66 and that “there has been no reported transmission to the community.” She added that the state doesn’t know the vaccination status of detained migrant adults or the children who entered the U.S. with them but that “all unaccompanied minors are vaccinated when they are detained.”

The Texas cases are not unique! Numerous similar outbreaks of mumps in have occurred in vaccinated children in New York, and in the U.S. Territory of Guam in 2009.[2]

So, the mumps outbreak at Texas detention centers occurred following children’s MMR vaccination!  Does anyone fail to see the connection between vaccination and an infectious disease outbreak?

CDC Pink Book acknowledges:

“From 1985 through 1988, 42% of cases occurred in persons who were vaccinated on or after their first birthday. During these years, 68% of cases in school-aged children (5–19 years) occurred among those who had been appropriately vaccinated. The occurrence of measles among previously vaccinated children (i.e., vaccine failure) led to a recommendation for a second dose in this age group.

During the 1989 -1991 measles resurgence, incidence rates for infants were more than twice as high as those in any other age group. The mothers of many infants who developed measles were young, and their measles immunity was most often due to vaccination rather than infection with wild virus. As a result, a smaller amount of antibody was transferred across the placenta to the fetus, compared with antibody transfer from mothers who had higher antibody titers resulting from wild-virus infection. The lower quantity of antibody [in the vaccine] resulted in immunity that waned more rapidly, making infants susceptible at a younger age than in the past.”

…  38% of measles cases in the U.S. were in vaccinated persons.

CDC further acknowledges that: despite relatively high vaccination rates, small measles outbreaks continue to occur. Since 2008, most of these outbreaks were imported or linked to importation from other countries. In 2011, CDC reported 220 measles cases – “62% were in persons not vaccinated.” That means that 38% of measles cases in the U.S. were in vaccinated persons.

The CDC Pink Book further acknowledges that: “Some studies indicate that secondary vaccine failure (waning immunity) may occur after successful vaccination”. Evidence of MMR vaccine-induced infection undermines the protective rationale for its indiscriminate, mass use, much less, mandating its use against parents’ objections.

200 measles cases in the U.S. do not justify the current media frenzy;

The empirical evidence is based on reality; the evidence cannot be wiped out by the faith-based “safe and effective” chant.

Empirical evidence refutes the faked epidemiological vaccine studies that are only draped with the mantle of “science”.

200 measles cases in the U.S. do not justify the current media frenzy; this frenzy is fomented by collaborating vaccine stakeholders with financial conflicts of interest who should be held accountable for subjecting an unknown number of children to defective vaccines – some of which were the cause of infectious disease outbreaks.

Two congressional hearings called for enforcement of mandatory childhood vaccination, citing the current measles outbreaks. The committees invited only vaccine promoters who endorsed mandatory vaccination of children, but not of adults.

February 27th hearing, the House Committee on Energy and Commerce:

Dr. Dr. Anthony Fauci, Director of the National Institute of Allergy and Infectious Diseases declared: “Risks from vaccines are almost non-measurable…” In an earlier interview with Frontline, Dr. Fauci is on record stating:

“We know historically that it’s much more difficult to get adults vaccinated for a variety of sociological and other reasons, whereas when you have the children, you can get it out of the way …”

Dr. Nancy Messonnier, director of the National Center for Immunization and Respiratory Diseases at the CDC declared:

“I do believe that parents’ concerns about vaccines leads to undervaccination, and most of the cases that we’re seeing are in unvaccinated communities. Outbreaks of measles occur when measles gets into these communities of unvaccinated people. The only way to protect against measles is to get vaccinated.”

March 5th hearing, Senate Health, Education, Labor & Pensions (HELP) committee:  John G. Boyle, CEO of the Immune Deficiency Foundation (whose core benefactors are bio-pharma corporations) upped the decibel, declaring:

“The current decline in vaccine usage is literally bringing back plagues of the past.”

Senator Rand Paul, a HELP Committee member, was the only member of the committee who voiced some reservations about the stampede toward depriving U.S. citizens of their human right to choose what’s in the best interest of their children!

Why is the public health armamentarium aimed at eliminating “unvaccinated” children rather than on preventing a true catastrophic epidemic of neurodevelopmental injuries in children?

The focus of concern and public anger should be directed at the failure of the public health establishment to methodically investigate the contributing cause[s] of the genuine, empirically documented childhood epidemic – the relentless, ever-increasing rise in the number of neurologically injured children has climbed to 1 in 36 in the U.S. The numbers of those affected is now in the millions.

*Witch Hunt defined: “the searching out for persecution and deliberate harassment of those with unpopular views” Merriam Webster’s; “a rigorous campaign to round up or expose dissenters on the pretext of safeguarding the welfare of the public” Collins English Dictionary.

References:

  1. Journal of Clinical Microbiology (2017)
  2. CDC. Pink Book, Chapter 15 Mumps
  3. CDC Pink Book, Chapter 13 Measles

Sign up for free news and updates from Robert F. Kennedy, Jr. and the Children’s Health Defense. CHD is planning many strategies, including legal, in an effort to defend the health of our children and obtain justice for those already injured. Your support is essential to CHD’s successful mission.

 

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Two Doctors Explain Autophagy, How To Induce It (Fasting) & What It Does To The Human Body (Video)

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In Brief

  • The Facts:

    Dr. Guido Kroemer and Rhonda Patrick sit down and discuss autophagy, how to induce it and it's health benefits.

  • Reflect On:

    Why do we never hear about fasting interventions as an 'official' treatment for certain from our federal health regulatory agencies when there is so much scientific proof?

Fasting and caloric restriction, if done correctly in a healthy and appropriate manner, combined with a healthy diet can have tremendous benefits for the human body. Interventions like fasting are gaining tremendous amounts of popularity, and that is in large part due to the fact that this information is being spread across the world via alternative media outlets and independent websites, youtube channels, etc. It’s not really a health topic that we’re hearing from mainstream media sources or our federal health regulatory agencies. Why? Because you can’t make money off of fasting. Perhaps when drugs are developed that mimic the effects of fasting, that’s when its popularity will skyrocket; but unfortunately, modern day health authorities don’t really seem to be as concerned with our health and wellbeing as they are about profiting and making money, and nobody is going to make any money if people starting eating less. That being said, the information revolution cannot be stopped, and fasting is now on the minds of many, and for good reason.

On October 3rd, 2016, the Nobel Assembly at Karolinska Institutet awarded the Nobel Prize in Physiology or Medicine to Yoshinori Ohsumi for his discoveries of mechanisms for autophagy, a term that translates to “self-eat.” In short, autophagy is the body’s self-cleaning system, a mechanism in which cells get rid of all the broken down, old cell machinery (organelles, proteins and cell membranes). It is a regulated, orderly process to degrade and recycle cellular components.

The process of autophagy is like replacing parts in a car—sometimes we need a new engine or battery for the car to function better. The same thing happens within each of our cells. During autophagy, old cellular debris is sent to specialized compartments within the cell called “lysosomes.” Lysosomes contain enzymes that degrade the old debris, breaking it down into smaller components to be reused again by the cell.

Scientists have found that fasting for 12 to 24+ hours triggers autophagy, which is thought to be one of the reasons that fasting is associated with longevity. There is a large body of research that connects fasting to improved blood sugar control, reduced inflammationweight loss, and improved brain function, and Oshumi’s findings provide greater insight into this research.

“Sporadic short-term fasting, driven by religious and spiritual beliefs, is common to many cultures and has been practiced for millennia, but scientific analyses of the consequences of caloric restriction are more recent… short-term food restriction induces a dramatic upregulation of autophagy in cortical and Purkinje neurons. As noted above, disruption of autophagy can cause neurodegenerative disease, and the converse also may hold true: upregulation of autophagy may have a neuroprotective effect.

Food restriction is a simple, reliable, inexpensive and harmless alternative to drug ingestion and, therefore, we propose that short-term food restriction may represent an attractive alternative to the prophylaxis and treatment of diseases in which candidate drugs are currently being sought.”

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If you look at the plethora of studies that’ve been published regarding caloric restriction and fasting, the benefits are overwhelming. These benefits are seen across the board, not just in humans, but in animals as well. Some of these benefits are talked about below in a fascinating interview and discussion between Dr. Rhonda Patrick  and Dr. Guido Kroemer. Dr. Patrick, as her website states, “is dedicated to the pursuit of longevity and optimal health and shares the latest research on nutrition, aging, and disease prevention with her audience. She has a gift for translating scientific topics into understandable takeaways for all levels of education and interest.” She has a lot of great content on her Youtube channel with some very interesting people who are leaders in their respective field.

Dr. Guido Kroemer is currently a Professor at the Faculty of Medicine of the University of Paris Descartes, Director of the research team “Apoptosis, Cancer and Immunity” of the French Medical Research Council (INSERM), Director of the Metabolomics and Cell Biology platforms of the Gustave Roussy Comprehensive Cancer Center, Deputy Director of the Cordeliers Research Center, and Hospital Practitioner at the Hôpital Européen George Pompidou, Paris, France. He is also a Foreign Adjunct Professor at the Karolinska Institutet, Stockholm, Sweden.

The Takeaway

The takeaway here is to recognize the potential of dietary interventions for certain ailments. It’s also to recognize the importance of seeking out knowledge and wisdom, and not just relying on your doctor for advice or prescription medications.

Related CE Articles on Fasting

How To Activate Autophagy: Your Body’s Self-Cleansing System

Autophagy, Fasting & Exercise: Scientist Reveal Multiple Ways You Can Slow Down The Process of Aging

The Complete Guide To Fasting & Reversing Type 2 Diabetes: A Special Interview With Dr. Jason Fung

Neuroscientist Shows What Fasting Does To Your Brain & Why Big Pharma Won’t Study It

Scientists Explain How Fasting Fights Cancer, Triggers Stem Cell Regeneration & Changes Your Brain (In A Good Way)

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