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10 Ways You Can Supercharge Your Dopamine Levels Without Medication

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“Dopamine is a neurotransmitter that helps control the brain’s reward and pleasure centers. Dopamine also helps regulate movement and emotional response, and it enables us not only to see rewards, but to take action to move toward them.”  

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There are a lot of articles on the internet about dopamine and how it affects your mood, behaviour, energy, and focus. What’s not commonly spoken about, however, is how dopamine is affected by your perception. Discussed more rarely still is the reason why your dopamine levels may be low. Below are 10 ways to increase your dopamine levels, courtesy of Power of Positivity, as well as my own observations regarding the underlying issues which may have led to each situation and how to tackle them.

Related CE Article:  Dopamine & Serotonin: Is Depression Really The Result of a Chemical Imbalance? 

1. Don’t Get Addicted

“Many people get addicted to something because it gives them some kind of instant gratification – drugs, alcohol, sex, pornography, shopping, and other addictive behaviors actually have the opposite effect on dopamine levels in the long-term. In essence, when we get overly addicted to something, the ‘reward circuitry’ of our brain kicks into overdrive and we crave the ‘quick hit.’ This is not a sustainable solution for dopamine production, which can and should be done naturally.” 

What’s missing here is the fact that addiction is quite often a result of low dopamine, meaning addiction is more of an attempt to fix an already existing problem. In essence, “the underpinning of your addictive personality is a lack of fulfillment from within, with a resulting urge to achieve fulfillment through substances, objects, or events that relieve the inevitable pain – for a while.” (source)

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“When we receive a reward of any kind, dopamine is released in our brains. Over time, this stimulus and release of dopamine can lead to learning. Researchers have recently found that how quickly and permanently we learn things relates directly to how much dopamine we have available in our brains. As we get rewarded over and over again for something, we learn that we should keep doing whatever that is very deeply, and it’s hard to unlearn those kinds of behaviours.” (source)

What this means is that low dopamine is a response to a lifestyle that doesn’t offer much in terms of reward to the person living it. It may be a response to the environment you’re living in, the clothes you’re wearing, the tight budget you’re working within, the relationship choices you’ve made or have been made for you, or a result of trauma where there was no perceived reward. It’s very easy to understand how dopamine levels may appear low when we consider all the potentials leading to less rewarding lifestyles and life experiences.

What’s necessary, then, is less of a ‘don’t get addicted’ approach and more of an ‘increase the rewards in your life’ style of applied advice. The fact is, you’ll constantly feel less fulfilled through low dopamine when you’re not (or are unable to) fill your day with things that inspire and reward you. What this means is, the most effective protection against addiction and the greatest advantage to high dopamine levels is a defense against low-rewarding activities and an offence of rewarding actions, activities, and ultimately, a lifestyle of fulfillment and achievement.

Also, because addiction is most often rooted in past traumatic experiences, where emotions create a fight-or-flight response that becomes rooted in your core emotions, it’s vitally important to seek proper and effective help in dissolving past trauma. Doing so can only help you perceive more rewarding experiences in your life, rather than filtering experiences through a ‘traumatized’ awareness.

2. Checklist Small Tasks

“Dopamine increases when we are organized and finish tasks – regardless if the task is small or large. So, don’t allow your brain to worry about things that need to be done. Instead, write these tasks down and then check them off one at a time. It’s been shown that it’s more satisfying to the brain’s dopamine levels when we physically check something off of our to-do list. Also, write down and check stuff off regardless if you can mentally remember the tasks.” 

While reading the book Principles of Self-ManagementI came across a brilliantly well-researched understanding of motivation when it comes to tasks. In short, if a task is greater than 25% of a change in a person’s routine, the person will be overwhelmed and feel incapable of achieving it. This leads them to self-defeat and self-sabotage to avoid accomplishing the task. On the other side, if a task is less than 10% different from a person’s normal routine, they won’t do it because it won’t have enough meaning for them to do so. As such, it’s wise to make sure you write down goals and tasks that are in between this 10-25% range of new behaviours and actions; otherwise, you just won’t do it.

However, this 10-25% range is simply a guide for tasks that are not directly linked to our highest values. In reality, if you can link a task to your highest values and see clearly how it will help you accomplish what’s truly most important to you, you’ll do it. If you can’t see how it will help fulfill your highest values, you’ll procrastinate, hesitate, and get frustrated in the attempt to do it. By linking a task to your highest values, you’ll both increase the chances of you doing it and also increase the reward you will feel when you accomplish it, a result of producing more dopamine in the brain.

3. Create Something

“For us writers, painters, sculptors, poets, singers, dancers, and other artists, we can identify with this. When we’re in creative mode, we can become hyper-focused. As a result, we can enter a state called flow. Dopamine is the brain chemical that allows us to achieve this state. The lesson is this: take up a hobby or activity in which you actually create something tangible. Try something like arts, crafts, auto repair, drawing, photography, or something else that sounds interesting.” 

Sparking your creative drive is an effective way to increase your potential for feeling great, achieving goals, and inspiring yourself through your accomplishments. However, it can also be a distraction from a feel-bad lifestyle, if it’s not maintained with a purpose in mind. Whenever you’re working on a project, creative or not, that truly inspires you, you’ll activate your ‘flow state,’ where time and space seem to stand still. So how to you determine what it is that truly inspires you?

The most important goal in revealing your most authentic creative energy is to remove the creative energies of other people from your life. So many of us look up to the creations of others, whether works of art or music, and their works or talents take up time and space in our own minds. This isn’t necessarily bad, but it can influence your own beliefs about what you can create. If you compare yourself to others and minimize yourself, you’ll repress your own creative ability. This can affect your dopamine levels, because if you can’t see your own creations as rewarding to you, as much as someone else’s, you’ll feel inferior and incapable.

One very effective way of neutralizing the influence other people have on your mind is to literally look at the negatives or downsides of their accomplishment. This isn’t to practice being a critic, but rather, enable you to de-infatuate with their creative powers and stop minimizing your own. Once you recognize that your creative endeavours can exist on the level of those you admire, through practice (just like they did), you’ll increase your ability to see your own creations as meaningful and rewarding.

 4. Exercise

“Same ‘ole, same ‘ole, we know. We’ve discussed repeatedly the importance and benefits of physical exercise, and we’re just going to add to this list again. So, not only does exercise help us relieve stress, achieve better physical health and make us more productive; it boosts our dopamine levels. More specifically, exercise increases multiple neurotransmitters – serotonin and endorphins, besides dopamine, receive a boost. Here’s something else cool: the exercise needn’t not be arduous. Simply taking a stroll or climbing some stairs will achieve a good dopamine jolt.” 

Exercise is important, but it can also become a crutch or an addiction if it’s not something being integrated into your daily life. Many people go to the gym to work out, yet don’t live a life that requires the body they’re building. Another thing is actually placing a value on exercise itself. Many people buy the gym memberships, yet never use them. So what’s the easiest way to make exercise a part of your life?

There’s a branch of exercise called ‘functional training’ in which exercises are tailored to help you with your daily tasks. This is much more helpful than just ‘workouts,’ because if you can train your body into a state where your daily tasks are not taxing on your energy, you’ll breeze through the day and have more energy at the end of it. Staying in a high energy state instead of being brought down by your daily tasks will help you be more inspired during your day and innately feel more inspired to exercise.

5. Get a Streak Going

“As with creating a checklist, getting a streak going is a great way to increase dopamine levels. For the purpose of this article, a streak is a visual reminder of how many days in a row you’ve achieved something.

Get a calendar specifically for this purpose: write down whatever goal you have and the days of the week or month when they are scheduled. For example, if you work out on Monday, Wednesday and Friday, mark these days on the calendar for the month. As you finish a workout, mark it off on the calendar. Keep a streak going, and you’ll keep the dopamine coming.”

While the ‘streak’ is a useful tool for celebrating accomplishments, it unfortunately has a downside: routine. Doing something enough times becomes a routine, especially if the action isn’t continuously fulfilling to your highest values. To counter this, try adapting the ‘goal’ or ‘action’ in terms of efficiency and effectiveness. By continuously finding ways to improve the performance of the behaviour, over time, you can look back at how many times you’ve done it, but also how much better you’ve become at it. This way, your performance becomes a competition with yourself, which increases your potential for feeling rewarded as you master a skill.

6. Increase Tyrosine

“Of the chemicals that make up dopamine, none are more important than tyrosine. In fact, tyrosine is considered the building block of dopamine. Therefore, it is important that you get enough of this protein. There’s a large list of foods that increase Tyrosine, including: Almonds, Avocados, Bananas, Beef, Chicken, Chocolate, Coffee, Eggs, Green Tea, Watermelon, Yogurt.” 

Food is a reward, not a chore. This is the difference between living to eat and eating to live. While it’s important to utilize foods to your advantage, it’s just as important to recognize that the brain is its own best pharmacy. Few foods actually make it past the blood-brain barrier and this actually includes tyrosine.

“Tyrosine is one of the 22 key amino acids that are used for building proteins around the body. In addition to this, however, it also raises the levels of certain neurotransmitters in the brain, namely dopamine and norepinephrine. These are famous for being ‘feel good’ chemicals that can help boost mood and elevate concentration, making tyrosine a popular nootropic. However, tyrosine is completely incapable of passing the BBB. This way, no matter how much of it you were to take, you’d feel almost no effects.” (source)

The truth is, tyrosine must be bonded with another molecule to make it past the blood-brain barrier, so tyrosine in itself isn’t capable of making significant impacts on the brain. However, through natural digestion and regulating healthy bodily function, it can assist the brain in having to work less on fixing an unhealthy system, which in turn can help increase the potential for dopamine and dopamine related good feelings.

7. Listen to Music

“Do you ever wonder why music makes you happy? I mean, we can be in the dumps one moment but once we put on our favorite jam, we’re swaying and shaking away…feeling pretty good about ourselves too! The reason for this is that listening to music increases dopamine levels. In fact, scientists say that listening to music has the same effect as eating our favorite foods or watching our favorite T.V. show. So, when you’re feeling down, throw on some of your favorite tunes and jam out!”

Listening to music can increase dopamine levels temporarily, but what we’re really looking for is a lasting fulfillment feeling so you can make your daily life enjoyable and productive for your goals. Also, popular music these days is often manufactured in such a way as to prey on your brain’s chemical dependency, making much of music a form of substance addiction.

However, music has been a part of human history since as far as we can see, so its influence on our brain is greatly appreciated. In fact, one of the greatest cultural appreciations throughout history has been music. So, listen to music, but just make sure it’s not the only source of dopamine in your life.

 8. Meditate

“As with exercise, we are discovering more and more benefits to meditation. We are again adding to the list. As we discussed, the human brain is susceptible to a variety of addictions. One other addictive habit that we have is overthinking. In fact, some Buddhists have a phrase for this addiction: ‘monkey mind.’

Overthinking is not merely a distracting habit, it’s also a genuine compulsion that leaves us in a perplexing state, while also having a negative effect on our spiritual development. However, scientists are finally catching up to what Buddhists have known for thousands of years: meditation and mindfulness are essential to a healthy mind.”

Meditation can be a highly effective form of dopamine increase if done properly, as it can weed out the mental influences which may be causing your chemistry to be less than desired. With the intent of reaching a state of self-fulfillment, meditation clears out the mental clutter and replaces it with presence and fulfillment for just being alive. This is a state available to every human and can help assist our daily lives by increasing our awareness of what feels good for us and what we don’t resonate with.

9. Take Supplements

“While there are some great ways to increase dopamine levels, sometimes we’re facing a time crunch. Fortunately, there are natural supplements on the market that have been shown to increase dopamine levels. Here are a few:

Acetyl-l-tyrosine: Another building block of dopamine. A healthy dose of this makes it easier for the brain to produce dopamine.

Curcumin: An active ingredient that’s also common in curry spices and turmeric.

Ginkgo Biloba: A tremendously popular wonder supplement that’s also believed to boost dopamine levels and keep it circulating in the brain longer.

L-theanine: Increases multiple neurotransmitters in the brain, including dopamine. Green tea is a terrific source for this.” (source)

While supplements can impact our dopamine response, they should by no means replace your own inner potential for fulfillment. That responsibility lies with you and you alone. However, with respect to inner wisdom, without knowing what feeling amazing actually feels like, it’s difficult to strive for it as a goal. Supplements can help us get there so we can have a reference point for what our potential can be. The trick is to facilitate change in our lives, enough so that the need for supplementation to feel good is lower than the feel goods we actually experience in our life.

10. Toxic Cleansing

“As miraculous as our bodies are, we do accumulate toxins and bacteria that is bad for us. Endotoxins are the kind that can cause our immune systems to get out of whack, and it also constrains the production of dopamine. Here are a couple tips for helping cleanse the gut of endotoxins: eat fermented food, get enough sleep, and resist the urge to indulge in fatty or sugary foods.”

Whenever you’re not fulfilled in your life, you run the risk of overindulging in sugary and sweet foods in an attempt to temporarily fulfill yourself. However, if you find fulfillment through the challenge and support of your day, you’re more likely to eat for the tasks you’re doing instead of eating just to feel good.

How you eat and how fulfilled you are are directly correlated. If you’re actively enjoying the challenges of your life, you’re more likely to consume foods that serve your highest interests and health, because you see a reason to eat well. Controlling how you eat is less important than finding fulfillment in what you do.

So the next time you find yourself craving that candy bar, ask yourself if there isn’t something else you could eat that could help you find fulfillment. Also, notice what you are doing at the time you’re craving sugar and ask yourself if it’s really something you need to do, or can you delegate it to someone else so you can get back to things that inspire you. By focusing on what inspires and fulfills you, you’ll find yourself actively seeking to better your health without having to really focus on it.

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Lebanese Hospital Becomes The World’s First To Go 100 Percent Vegan (Food)

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CE Staff Writer 7 minute read

In Brief

  • The Facts:

    A hospital in Lebanon has become the first in the world to adopt a completely vegan menu.

  • Reflect On:

    Are people aware of the physical and emotional torture the majority animals we eat go through? Are people aware that a diet free of animal products can be very beneficial for human health. Are people aware that animal agriculture is destroying Earth?

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Take a moment and breathe. Place your hand over your chest area, near your heart. Breathe slowly into the area for about a minute, focusing on a sense of ease entering your mind and body. Click here to learn why we suggest this.

At the beginning of March, Hayek Hospital in Beirut, Lebanon became the first hospital in the world to serve 100 percent vegan only meals. Prior to this change, patients had a choice between animal based meals and vegan meals, and included with that was information about the health benefits of choosing plant-based foods versus the dangers of consuming animal products. The hospital made the announcement via their Instagram page, stating that “Our patients will no longer wake up from surgery to be greeted with ham, cheese, milk, and eggs…the very food(s) that may have contributed to their health problems in the first place.”

When the World Health Organization classifies processed meat as a group 1A carcinogenic (causes cancer) same group as tobacco and red meat as group 2A carcinogenic, then serving meat in the hospital is like serving cigarettes in a hospital. When the CDC (Centers for Disease Control and Prevention) declare that 3 out of 4 new or emerging infectious disease comes from animals. When adopting a plant based exclusive diet has been successfully proven not only to stop the evolution of certain diseases but it can also reverse them. We then, have the moral responsibility to act upon and align our beliefs with our actions. Taking the courage to look at the elephant in in the eye.

Their various statements also point to the role that animal agriculture plays in spawning infectious diseases, citing the Centers for Disease Control’s estimate that 3 out of 4 new or emerging infectious diseases come from animals. “We believe it’s well about time to tackle the root cause of diseases and pandemics, not just treat symptoms,” they note.

This was a great statement. The modern day medical industry only seems to be focused on medications, and only medications that can turn a hefty profit, to treat and cure disease instead of addressing root causes. It’s good to see things changing, but a big problem remains. If a plant that grows in abundance, for example, has the potential to cure a disease, will we ever hear about it? Will the medical industry be interested in it? Probably not, but when a drug is made and patented from that plant in a specific way, that’s when we will. This is not to say that modern day medicine is useless, but today now more than ever a big problem exists, and this problem may be killing more people than it’s helping.

Arnold Seymour Relman (1923-2014), a Harvard professor of medicine and also a former Editor-in-Chief of NEMJ, was frustrated that “the medical profession is being bought by the pharmaceutical industry, not only in terms of the practice of medicine, but also in terms of teaching and research. The academic institutions of this country are allowing themselves to be the paid agents of the pharmaceutical industry. I think it’s disgraceful.” (source)

According to Forks Over Knives,

While Hayek is the first hospital to completely purge animal products from its menu, a number of hospitals have begun offering more plant-based options in recent years. Both New York and California have enacted laws requiring hospitals to offer a plant-based option with every meal. In 2018 NYC Health + Hospitals/Bellevue launched the Plant-Based Lifestyle Medicine Program to help patients transition to a whole-food, plant-based lifestyle.

The American Medical Association passed a resolution in 2017 calling on U.S. hospitals to provide healthful plant-based meals to promote better health in patients, staff, and visitors. The American College of Cardiology has issued similar recommendations.

In my opinion, “veganism is a very fine form of nutrition” (Dr. Ellsworth Wareham, heart surgeon), and as mentioned above, there is plenty of science to back up that statement.  I’ve written about it many times before from a health perspective.

Here’s an article that goes into more detail and science if you’re interested, it also addresses history, and how our teeth and guts are designed and more. Here’s another one regarding a study that found a strong association between eating animal protein and a premature death from all causes, including multiple cancers and type 2 diabetes.

The studies cited in that article note that meat eating is strongly associated with up to a 75 percent increased chance of early mortality, and that protein from animals may cause harm, while protein from plants may help reverse disease and have a protective effect.

There are hundreds of these studies, and the ones I cite are just a few examples.

This is obviously a very controversial topic in the eyes of many, and it’s not hard at all to find conflicting information on the subject. I am no doubt bias in my beliefs and opinions here.

One thing is for certain, the way we treat animals on this planet is extremely heartbreaking and unnecessary. Animals are separated from their families, raised for slaughter and are kept in torturous conditions on a daily basis. It’s truly unbelievable and horrific. It’s the biggest genocide and example of both physical and emotional torture the world has ever seen. I don’t think anybody can witness what really goes on in most slaughterhouses can come out not being impacted.

On top of this, animal agriculture is one of, if not the greatest contributer to environmental degradation and pollution on our planet. Animal agriculture is actually the leading cause of deforestation. Every single day, close to 100 plant/animal/insect species are lost because of this practice.

Final Thoughts: At the end of the day it seems that, from a health perspective, processed meats, and other meats are no doubt harmful to human health. People can make the argument that other animal products may not be and that we are meant to consume them. People can also make the complete opposite argument. One thing that can’t be argued is, again, the torture, physical and emotional abuse that comprise the source of where animal products come from for the majority of people who eat them.

There is a big split, as with many other topics, amongst people on this issue. There are even vegan influencers who are creating splits within the ‘vegan community’ itself, which is unfortunate. I personally believe that, from a health perspective, animal products are not at all required for anybody and are again, overall, harmful to human health.

The more pressing issue, again, is the treatment of our animal brothers and sisters, and how we are constantly using and abusing them. It’s indicative of world that lacks empathy, compassion, understanding and love, as well as our inability to see ourselves in another. This can be seen in many aspects of the current human experience, be it war, human trafficking and more. That being said, it’s great to see human consciousness shifting towards a more compassionate, empathetic type of awareness. This is evident by the “vegan” movement alone, as it’s become quite large over the past few years and will continue to grow. Some of the biggest animal food producers have already gone out of business, and it’s great to see more people in the health community as well recognize that it’s a win for health, a win for environment, and most importantly, a win for the very emotional, intelligent, animals, who are similar to us in so many ways. We have so much to learn from them.

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Caloric Restriction vs. Fasting: Why One Can Result In Weight Gain While The Other Helps Burn Fat

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In Brief

  • The Facts:

    In the video below, Dr. Jason Fung explains the difference between caloric restriction and sending the body into "starvation" mode compared to fasting.

  • Reflect On:

    Fasting has been used as a health intervention for thousands of years, and is being used today by doctors who are educated on the topic. Why is it completely ignored by mainstream medicine? Is it because "big pharma" can't make any money off of it?

Before you begin...

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Take a moment and breathe. Place your hand over your chest area, near your heart. Breathe slowly into the area for about a minute, focusing on a sense of ease entering your mind and body. Click here to learn why we suggest this.

Some would say that the best solution to weight gain is eating right and exercising. I couldn’t agree more. Obesity is one of the deadliest problems humanity faces today, and just as important as diet and exercise is for addressing this issue, even more important are the emotional and personal reasons as to why so many people damage themselves and make themselves more prone to serious disease.

Apart from diet and exercise, initiating a proper fasting regimen can have tremendous health outcomes, especially for overweight people. It wasn’t but a decade ago when fasting to lose weight was considered unhealthy and dangerous. Today, we have a tremendous amount of science that’s been published clearly showing that fasting can be an effective health intervention for people of all body types, especially for people who are overweight and suffer from certain diseases. It’s an excellent way to help your body burn fat. Fasting has been used and is currently being used as an intervention for type two diabetes, cancer and more. Fasting has been shown to trigger stem cell regeneration, autophagy, which in turn can help clear out toxins and damaged cells, repair DNA, improve metabolism, lower blood sugar, boost brain function, reduce the risk of age related disease, lessen inflammation which improves a wide range of health issues from arthritic pain to asthma and more. It’s no wonder why so many ancient cultures from different parts of the world used fasting as medicine and as a health intervention.

As shown in the science, fasting is generally safe for everybody. This many not be true if you already have underlying health conditions or are taking certain medications. This is why it’s important to consult a health professional about it, but the issue is, the majority of health professionals are not well educated in fasting interventions. Those who have educated themselves have been treating their patients with fasting and are drawn to it due to its ability to provide so many benefits.

One of these doctors is Dr. Jason Fung, who on his blog and his YouTube channel, as well as the books he’s written provides a wealth of information and science regarding fasting. I often refer people to the work of Fung, or others like Dr. Valter Longo if they want to begin their own research about fasting. Again, there is a wealth of science and “scholarly” articles available on the subject for anybody who wants to search for it as well. It’s not heard to find.

In the video below, Fung explains why fasting is much different from caloric restriction or having your body go into “starvation mode.”  You can also check out his article, “The difference between calorie restriction and fasting” for some great information as well.

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Click below to watch a sneak peek of our brand new course!

Our new course is called 'Overcoming Bias & Improving Critical Thinking.' This 5 week course is instructed by Dr. Madhava Setty & Joe Martino

If you have been wanting to build your self awareness, improve your.critical thinking, become more heart centered and be more aware of bias, this is the perfect course!

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The Deeper Questions Behind The “Lab Origins” Debate

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13 minute read

In Brief

  • The Facts:

    It is being slowly accepted that SARS-COV2 originated in a laboratory. The delay in this admission has not been due to media "spin" alone but from scientists themselves.

  • Reflect On:

    How can we "trust the science" if the scientists are being disingenuous?

Before you begin...

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Take a moment and breathe. Place your hand over your chest area, near your heart. Breathe slowly into the area for about a minute, focusing on a sense of ease entering your mind and body. Click here to learn why we suggest this.

As the majority of Americans gather around the prevailing voice of our trusted medical institutions, those opposing it seem to be digging in their heels as well. Why is this happening? After all, we are not arguing over religion or political ideology (or at least we shouldn’t be). This pandemic and its management falls squarely in the realm of science, something that should be objective and indisputable. How is the layperson supposed to make sense of the growing polarity concerning this issue? Unless one has related training in virology, epidemiology, statistics and a decent understanding of the history and the sequence of investigations that have led scientific opinion to consensus positions before this pandemic, there is no way to be “scientific”. How are we to know whether the edicts coming from our leaders are reasonable and founded? This puts us in a difficult position, one that we are unable or unwilling to acknowledge: we have to trust someone else. The question is, whom?

Mainstream Media is beginning to acknowledge that SARS-COV2 originated in a lab

There has recently been a shift in the mainstream narrative. Some of these mainstream sources have been willing to take a hard look at where this virus came from: the “lab origins” thesis. In this recent interview with evolutionary biologists Heather Heying and Bret Weinstein, popular satirist and political commentator Bill Maher admits that “it would almost be a conspiracy theory to think it didn’t start in a lab.” The reasons for this are clear to anyone who has looked beyond the veil of simplistic statements and abjectly poor investigative journalism coming from mainstream sources. Gain of Function studies on SARS viruses were being conducted in publicly funded laboratories in this country for years prior to 2014. One could argue this was part of bioterrorism research just as easily as it was part of a pandemic preparedness effort. It is not so hard to see that in order to be prepared to combat a highly contagious and virulent pathogen we must be able to study the pathogen itself. Pandemic preparedness and bioterrorism research are basically the same thing.

As the story unfolds in the mainstream narrative, it is becoming apparent that the wet market hypothesis will soon be jettisoned for its sheer implausibility. Is it likely that this virus could survive in a bat or pangolin for generations while mutating in such a way that it could not only immediately survive in a human body but be so virulent as well? What are the factors that would be involved in allowing this new strain to behave unlike previous SARS viruses in terms of its copious presence in our nasopharyngeal cavities, apparent transmissibility in the asymptomatic and enduring pathogenicity when floating around in the air or lurking on surfaces? The answer is far more than one, making this wet market to global pandemic story all the more unacceptable.

As establishment science comes to its senses, we are left with the reality that the pandemic has most probably been the consequence of a laboratory research that got out of control. It may not be excusable or forgivable but at least we can take comfort that our attention has been refocused on what is plausible. However simply acknowledging the high probability of lab origins and moving forward with all the same initiatives to combat this virus is not enough. There are more questions that need to be posed first.

How did some Scientists “spin” the science?

This argument over SARS-COV2 origin is not new at all. It was being hotly debated a year ago for some of the same reasons I mentioned above. The lab origin thesis was effectively (and prematurely) purged from “acceptable” discussions when a paper entitled “The Proximal Origin of SARS-COV2” (KG Anderson et al) appeared in Nature Medicine (March 17, 2020). This piece served as the foundation of a wall of scientific opinion that was rapidly erected to contain the dangerous “conspiracy theory” that the virus was a product of human intention and ingenuity. If you were to read the piece it would be hard to not end up shrugging your shoulders and going along with the authors’ thesis. The authors are well-respected and published scientists that include W. Ian Lipkin, pathologist, neurobiologist and epidemiologist at Columbia University,  internationally recognized for his work around W. Nile Virus and SARS. They are assured in their conclusions and offer the reader, among other things, a comparative study of the peptide structure and genetic sequence of this virus and closely related variants. 

I am a physician and was led to this piece months ago in my research into this topic. I admit that I was left scratching my head. It wasn’t until I tuned in to a blog surrounding this and other issues hosted by Dr. Meryl Nass, a respected and dutiful researcher of pandemics and bioterrorism, that l was able to grasp where the misdirection was introduced. Dr. Nass correctly points out that it may not be possible to irrefutably prove that the virus was of lab origin or not, however it is the erroneous assumptions and unsound logic the authors of the Nature Medicine article use that point to the obscuration of the facts in a manner we could reasonably deem as deliberate.

After presenting us with a thorough description of the structure of SARS-COV-2 and analysis of its means of entering human cell lines via the Angiotensin Converting Enzyme 2 (ACE2) receptor, the authors introduce their challenge to the lab origins position. The authors state:

“While the analyses above suggest that SARS-CoV-2 may bind human ACE2 with high affinity, computational analyses predict that the interaction is not ideal and that the RBD sequence is different from those shown in SARS-CoV to be optimal for receptor binding. Thus, the high-affinity binding of the SARS-CoV-2 spike protein to human ACE2 is most likely the result of natural selection on a human or human-like ACE2 that permits another optimal binding solution to arise. This is strong evidence that SARS-CoV-2 is not the product of purposeful manipulation.”

Anderson et al are presenting their first line of attack on the Lab Origins hypothesis. Because their computational analysis predicts that a different and more “optimal” receptor-binding domain (RBD) portion of the spike protein on SARS-COV-2 could have been built, they say, it must have arisen naturally. The authors are assuming that if the virus was the product of bioterrorists they would have designed it differently. Is this sound logic? It is not. First, the authors are presupposing that their computational method is the only one available for use. Second, there is no reason to assume that a bioterrorist would choose the genetic solution that was “optimal”. Moreover, picking a “solution” identical to a computationally derived genetic sequence would leave an obvious clue that human hands were involved. This is in fact what the authors are correctly pointing out. 

This line of reasoning sheds light upon their foundational assumptions about the sophistication and intentions of would-be bioterrorists. Are they experimenters in laboratories building a novel coronavirus to a computer model’s specs to study it? Or are they true bioterrorists seeking to design a bioweapon that has no trace of human manipulation? Obviously one cannot know. Making either assumption cannot be part of any rigorous forensic analysis.

The authors go on:

“It is improbable that SARS-CoV-2 emerged through laboratory manipulation of a related SARS-CoV-like coronavirus. As noted above, the RBD of SARS-CoV-2 is optimized for binding to human ACE2 with an efficient solution different from those previously predicted. Furthermore, if genetic manipulation had been performed, one of the several reverse-genetic systems available for betacoronaviruses would probably have been used. However, the genetic data irrefutably show that SARS-CoV-2 is not derived from any previously used virus backbone.”

Here the authors are introducing yet another unfounded assumption: If the virus was designed as a biological weapon, why would a known coronavirus backbone necessarily be used as a basis for genetic manipulation? Certainly that option would be entertained by a team of bioterrorism researchers, but it is illogical to begin with that assumption. There are undoubtedly coronavirus backbones that have been genetically manipulated and remain behind closed doors and outside of public databases, i.e. unknown. It is equally logical to conclude that because no known backbone was used the virus was purposefully manipulated.  

In any case, genetic manipulation is not the only way to create a backbone of a virus. The oldest way is to use passage, a laboratory technique where a virus is cultured through a series of cell lines from different species resulting in a viable product that will survive in the target species. Other techniques are also readily available: exposing a known virus to mutagenic factors, collecting those that survive and repeating the process or simply mixing related viruses together to see what recombinant products result. None of these methods will result in a “solution” that would be in any way predictable at the outset. Indeed, that is the advantage of using such techniques. This is a fact that is well known to virologists, making the authors’ analysis all the more suspicious.

It is undeniable that the authors were using poor logic and unfounded assumptions to make unsound conclusions. This should have been obvious to the scientific community at that time, and this paper should not have made it through the editorial process of such a respected publication as Nature Medicine. The disquieting thing is that quite the opposite occurred. The article instead served as the seminal piece to squelch all arguments for the lab origin hypothesis once a flurry of subsequent publications cited it. Who should be held accountable for this? The authors? The editorial committee of Nature Medicine? The cadre of scientists that chose to use this publication to “manufacture consensus”? The mainstream media for failing in their responsibility to offer a balanced view of the debate around this article? None can be held solely responsible and all were required to perpetuate the distortion. The implications here are very serious and impossible to ignore.

Who can we rely upon to faithfully report “the science”?

Are there no stops to the dissemination of baseless “scientific” opinion? This is a question that rarely gets asked because we tend to assume that in the end, scientific consensus will be reached without the need for oversight. We are talking about science and scientists here, not policy makers or private industrialists with conflicts of interest and personal gains that hang in the balance. Yet the lines between science, industry and policy-making are blurrier the closer we look. In any case, who can we rely upon to ensure that the scientists are doing their job in formulating sound approaches to the problems at hand? There isn’t anyone, other than the scientists themselves. So what went wrong here? How did the Anderson paper end up deftly hamstringing a viable theory about the origins of SARS-COV2 a year ago using specious logic and unnecessary assumptions? Why didn’t anyone say anything? Despite what is generally known, many did.

Here’s where things get hopeful, depending on how you look at them. It would be wrong to dismiss all virologists, epidemiologists and researchers as slaves to corporate funded research institutions and group-think. Behind the veil of headlines that tout the rigor of the data and fuel the “trust the science” mantra there are collections of perspicacious and tireless researchers and journalists that have been pushing back against the established opinion and raising valid concerns about the hijacking of the narrative by members of their own ilk. Notably RFK Jr.’s Children’s Health Defense and Dr. Joseph Mercola have published an excellent paper that comprehensively summarized the ongoing work of Dr. Alina Chan of MIT’s Broad Institute who has documented the timeline and significance of how the spin has been manufactured by the scientific community themselves. Of course, many are familiar with Mr. Kennedy and Dr. Mercola not because of what they are bringing to complex discussions but because of their stigmatization as purveyors of “anti-vax” and “pseudoscience” opinions. Once so marked they are felled by the mainstream media machine with all the efficiency and discrimination of a logger’s chainsaw in an old-growth forest.

There are others that are broadcasting the same signal of reason. DRASTIC (Decentralized Radical Autonomous Search Team Investigating Covid-19) is a group of independent scientists, journalists and researchers that have been bringing attention to the suspicious ways that the debate surrounding the origin of SARS-COV2 has been marginalized within the scientific community itself (more about their work here). For example, “A Statement in support of the scientists, public health professionals and medical professionals of China combatting Covid-19” appeared in the correspondence section of the esteemed medical journal Lancet in March of 2020. In this letter the authors explicitly characterize any dissent to the natural origins hypothesis as “rumour, disinformation and conspiracy theories”. 

What are we to make of such accusations leveled against scientists by scientists? This sort of rhetoric has no place in any scientific discussion of any kind and should be a matter of real concern for everyone. Has science been corrupted by the same forces that are undeniably turning investigative journalism into a means of promulgating propaganda in some instances? If that were the case, how then are we to “trust the science”?

The Predicament that we are in

We are in an uncomfortable situation. Unless we can independently dismantle the arguments like those in the Anderson paper, or can understand the significance of the appearance of a mysterious 12 nucleotide sequence in the SARS-COV2 genome that confers the virus with a polybasic furin cleavage site (resulting in a substantial increase in virulence described here), or can appreciate the implications of a situation where scientific journals publish papers without requiring authors to supply the raw data required for independent genomic confirmation, we are stuck. If the science is being spun or misrepresented or poorly reported, there would be no way to know it.

Determining the origin of SARS-COV2 is an important question that still needs to be answered definitively. Attempting to answer this question has brought light to more disturbing questions. We cannot expect the layperson to comprehend the scientific studies that underpin our approach to this pandemic, let alone critique the logic and assumptions made by the authors of these papers. Expecting that a news correspondent, mainstream or otherwise, is anymore capable of dissecting such information is not realistic either. Until we come to grips with this we will not be able to grasp the enormity of the crisis we are facing.

The Takeaway

An honest examination into the origin of SARS-COV2 suggests a danger more pernicious than the virus itself. How much of scientific opinion is dictated by non-scientific interests? How many other “consensus” positions are rooted in inexcusably poor reasoning and assumptions? If we can only rely on independent researchers to bring clarity to these topics, who is going to give them a voice? If there is a fact that can be extracted from this debate it would be that “trusting the science” and trusting what a media source says about “the science” can be two very different things. 

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