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The CDC’s Greatest Cover Up? Information About Lyme Disease They Don’t Want You To Know About

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Lyme disease, do you have it? If you did, you probably wouldn’t know – unless you’re one of the chronic sufferers that have had to visit over 30 doctors to get a proper diagnosis. Lyme disease tests are highly inaccurate, often inconclusive or indicating false negatives.

Why? Because this clever bacteria has found a way to dumb down the immune system and white blood cells so that it’s not detectable until treatment is initiated. To diagnose Lyme properly you must see a “Lyme Literate MD (LLMD),” however, more and more doctors are turning their backs on patients due to sheer fear of losing their practices! Insurance companies and the CDC will do whatever it Ttakes to stop Chronic Lyme Disease from being diagnosed, treated, or widely recognized as an increasingly common issue.

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Lyme is considered by the medical field to “only” transmit by way of a tick infected with bacteria. However, the CDC itself admits it is under-reported, and believes there are between 300,000 to half a million new cases each year. That makes Lyme disease almost twice as common as breast cancer and six times more common than HIV/AIDS. Where are all of these new cases coming from? (It’s interesting to note that since Avril Lavigne recently went public with her Chronic Lyme Disease battle, mainstream news outlets like The Daily Mail have been mentioning Lyme can be transmitted by mosquitoes, too!)

lyme-disease-tick

When Lyme isn’t detected in the early stages, it becomes Chronic Lyme, a condition which the CDC and IDSA both deny even exists. They will continue to deny it, because if there’s one thing insurance companies hate, it’s chronic disorders they have to spend time and money treating. Therefore, a panel with ties to insurance companies gathered to write up official Lyme guidelines that assure patients are only allowed a few weeks of antibiotic treatment and are not to be diagnosed with Chronic Lyme Disease (even if clear symptoms persist and invade the nervous system). Over half of the panelists who wrote the IDSA Lyme guidelines announcing that Chronic Lyme is not real — including the panel chairman — have obvious conflicts of interest including financial interests in drug companies, diagnostic tests, and patents, as well as consulting agreements with insurance companies. Researchers and scientists with evidence in support of Chronic Lyme were intentionally excluded from the panel. Because of these unjust Lyme guidelines, insurance companies have the “right” to deny coverage for the treatment of long-term Lyme disease. Doctors have even lost their practices for successfully diagnosing and treating Chronic Lyme, as shown in the film Under Our Skin. In the case of Dr. Joseph Jemsek of North Carolina, he not only lost his license, but also his livelihood. Dr. Jemsek can no longer practice simply because he gave antibiotics to Chronic Lyme sufferers, and was then sued by BCBS for 100 million dollars, following which he had to declare bankruptcy. You can read his closing remarks to the NC Medical Board just before they pulled his license here. You can also watch his story in the documentary at the end of this post.

Busted – Big Pharma bucks taint the IDSA

Connecticut Attorney General Richard Blumenthal investigated the IDSA panel members for possible violation of antitrust laws and conflicts of interest.

Of the 14 panel authors of the first edition guidelines: 6 of them or their universities held patents on Lyme or its co-infections, 4 received funding from Lyme or co-infection test kit manufacturers, 4 were paid by insurance companies to write Lyme policy guidelines or consult in Lyme legal cases, and 9 received money from Lyme disease vaccine manufacturers. Some of the authors were involved in more than one conflict of interest. (Source: ‘Under Our Skin [2008])

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Study: Strong Evidence Of Sexual Transmission

The bacteria that causes Lyme disease is Borrelia burgdorferi, a type of corkscrew-shaped bacteria known as a spirochete. The Lyme spirochete is a cousin to Treponema pallidum, the spirochete that causes syphilis.

Dr. Alan MacDonald, MD who appears in the documentary ‘Under Our Skin’ (2008), says in the film that he found found Borrelia (Lyme) DNA in 7 out of 10 postmortem Alzheimers patients’ brains. This makes perfect sense, since syphilis, its cousin, also invades the brain in tertiary or neurosyphilis. Dr. Klinghardt, MD (also quoted from ‘Under Our Skin’) stated that he’s “never had a single patient with Alzheimer’s, ALS, Parkinson’s Disease or Multiple Sclerosis who tested negative for Borrelia.”


Dr. Alan MacDonald, MD talks about Lyme.

Why are so many people suffering from Lyme disease and its allegedly associated chronic disorders, such as Alzheimers and ALS? A new study suggests that just like its spirochete cousin that causes syphilis, Lyme disease may be sexually transmitted! The study was presented at the annual Western Regional Meeting of the American Federation for Medical Research, and an abstract of the research was published in the January issue of the Journal of Investigative Medicine.

Medical Daily reports,

The study — presented at the annual Western Regional Meeting of the American Federation for Medical Research — a collaborative effort by an international team of scientists — tested semen samples and vaginal secretions of three groups of patients to investigate whether passing Lyme disease to a partner through unprotected sex is a possibility. The study observed control subjects without evidence of Lyme disease, random subjects who tested positive for Lyme disease, and married heterosexual couples engaging in unprotected sex who tested positive for the disease. The presence of B. burgdorferi and identical strains of the bacterium were of particular interest to the researchers in unprotected sex in spouses.

The control subjects were found to test negative for the bacterium in semen samples or vaginal secretions, as expected by the researchers. The researchers found traces of B. burgdorferi in the vaginal secretions of all women with Lyme disease. In contrast, approximately half of the men with the disease tested positive for the bacterium in semen samples. In addition, one of the heterosexual couples with Lyme disease were found to have identical strains of the bacterium in their genital secretions.

One researcher in the study notes, “There is always some risk of getting Lyme disease from a tick bite in the woods. But there may be a bigger risk of getting Lyme disease in the bedroom.”

“Our findings will change the way Lyme disease is viewed by doctors and patients,” said Marianne Middelveen, lead author of the study. “It explains why the disease is more common than one would think if only ticks were involved in transmission.” But will this actually change the way Lyme disease is viewed? Or will the money funneled in by insurance companies and vaccine manufacturers continue to blind and corrupt the IDSA board members? When is enough, enough?

The study was a joint effort by a team of scientists which included dermatologists, molecular biologists, microbiologists, internists, and family practitioners. The most revealing aspect of the study, in my opinion, is the fact I mentioned earlier: one of the heterosexual couples with Lyme disease showed identical strains of the Lyme spirochete in their genital secretions. “The presence of the Lyme spirochete in genital secretions and identical strains in married couples strongly suggests that sexual transmission of the disease occurs,” said Dr. Mayne.

Gestational Transmission From Mother To Child

From LymeDisease.org:

A North Carolina State University researcher has discovered that Bartonella (a common Lyme co-infection) can be passed to unborn babies, causing chronic infections and possibly birth defects. Dr. Ed Breitschwerdt and his research group tested blood and tissue samples taken over a period of years from a mother, father and son who had suffered chronic illnesses for over a decade. Autopsy samples from their daughter–the son’s twin who died shortly after birth–contained DNA evidence of B. henselae and B. vinsonii subsp. berkhoffi infection, which was also found in the other members of the family. Breitschwerdt’s research appears online in the April 14 Journal of Clinical Microbiology.

You can read a transcript of one of Breitschwerdt’s interviews on Bartonella here.

Multiple Strains Of Lyme?

In 2002, W.T. Harvey, an MD from Houston, began finding large numbers of chronically ill Borrelia burgdorferi PCR- and seropositive patients in the area around his home and practice. Houston, Texas is declared a zoonotically “non-endemic” area, so he set out to understand just how this epidemic was occurring. W.T. Harvey had no competing financial interest (as the CDC and IDSA do) and received no grants when writing his study on Lyme.

“In order to understand this finding prior to sufficient data availability, we chose to examine critically the currently accepted but troublesome ‘Lyme disease’ concepts,” Harvey’s study reads. “Our method was to analyze each foundation ‘Lyme disease’ premise within the context of available medical and veterinary literature, then to reconstruct the disease model consistent with the preponderance of that data. We find the present conceptualization of the illness seriously truncated, with a high likelihood of two distinct but connected forms of human B. burgdorferi infection. The yet-unrecognized form appears to have a broader clinical presentation, wider geographic distribution, and vastly greater prevalence. We conclude that ‘Lyme disease’ currently acknowledges only its zoonosis arm and is a limited conceptualization of a far more pervasive and unrecognized infection state that must be considered a global epidemic.

Could You Have Lyme From Your Pets?

Suzy Cohen of suzycohen.com is a registered pharmacist and best-selling author. When she graduated from pharmacy school in 1989, she believed that medication was the answer to helping patients get healthy. When that didn’t always work, she began to do some serious research. In one article addressing the truth about Lyme, she writes:

“Most Lyme sufferers have pet cats and dogs, they are not aware that their pets gave it to them. But it happens like this, your pets go out into the yard to do their duty, and ticks jump on them, especially in May and June, their breeding season but any time of the year is possible. Your pet totes these ticks into your house and then you cuddle with your pet. The ticks get on you, and numb your skin. They are teeny tiny, about the size of a poppy seed and you’ll never know you got bit. They like every part of your body, but especially warmer areas, like armpits for example. You may never know. Sometimes the Lyme can happen from a cat scratch or bite. When I ask pet owners about their pets, they go into a bit of denial, because of the great love they have for pets. But you have to realize pets, for as delightful as they are, are tick taxis. If you have Lyme, and get bit again by your pet, you are potentially introducing new coinfections or re-innoculating yourself with more Lyme organisms. It explains why some people just can’t get well, or get setbacks even under treatment.”

Borrelia spirochetes have been found in the urine of infected dogs, among several other animals. Studies on mice have found that the spirochetes in urine remained viable for 18-24 hours and concluded that “[u]rine may provide a method for contact non-tick transmission of B. burgdorferi in natural rodent populations particularly during periods of nesting and/or breeding.” Evidence for direct contact transmission has been demonstrated in mice. These findings suggest that further research is needed to evaluate alternate methods of Lyme transmission, such as by the urine of infected animals to humans. 

Conclusion & How To Learn More:

“Lyme is one of the many microbes that has entered our system. And I feel as a physician that things are getting to a degree that’s serious. We’re watching other mammals die out and just think, ‘well, I’m glad it’s not me.’ However, as our environment becomes increasingly polluted, so do our bodies. And then we grow bugs [parasites, pathogens] in us that are not compatible with human life anymore.” 
Dr. Klinghardt, MD, ‘Under Our Skin’ (2008).
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As Dr. Klinghardt said, this is getting serious. Or as Dr. Harvey put it, this is an epidemic. These patients, along with solid science, are being purposefully ignored because IDSA panelists have been bribed and bought. 

Could you have Lyme? I suspect I might after a series of flea bites in 2011, and I’m almost positive my mother has had it for a very long time. Her doctors are finally thinking the same. This is no shock to me; as Dr. Klinghardt stated above, Lyme is one of the many microbes that has entered our system. We are all exposed to pathogens and parasites on a daily basis, and are never taught anything about how to cleanse or maintain a largely uninhabitable inner environment (hint: a strong immune system)! In fact, I’m on my third parasite cleanse and still passing worms. What else are we housing that we don’t know about? Why is all of this information ignored?

Lyme presents itself in symptoms often misdiagnosed as Crohn’s Disease, Chronic Fatigue Syndrome, ALS, MS, Alzheimer’s, Colitis, Encephalitis, Fibromyalgia, Fifth’s Disease, Arthritis, Cystitis, IBS, Lupus, Prostatitis, Psychiatric Disorders (bipolar, depression), Sjogren’s Syndrome, sleep disorders, thyroid disease, and more.

This is a long list, and the number of people who go misdiagnosed or undiagnosed altogether is staggering. As I said, Lyme and hundreds of other pathogens and parasites have taken up residence in our bodies. We have improved our outer practices of hygiene, yet have increased our sources of autointoxication: GMO foods, processed food-like products, overeating, fluoride in water, and chemicals in everything from household cleaners to plastics – just to name a few.

Please watch “Under Our Skin” to learn more about Chronic Lyme disease and how the medical industry continues to ignore this epidemic. The full documentary is available here with a short preview below.

A Quick Important Notice:

The demand for Collective Evolution's content is bigger than ever, except ad agencies and social media keep cutting our revenues. This is making it hard for us to continue.

In order to stay truly independent, we need your help. We are not going to put up paywalls on this website, as we want to get our info out far and wide. For as little as $3 a month, you can help keep CE alive!

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Awareness

22 Out Of 25 Popular Burger Chains Just Failed Their Antibiotic Use Report

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In Brief

  • The Facts:

    A recent study was done examining how well top fast food chains actually implemented their antibiotic use policies in their beef. 22 of 25 failed including McDonald's, Sonic, Burger King and In-N-Out.

  • Reflect On:

    Do you still eat fast food? If so, why do you find yourself doing so? What healthier choices can be made instead? If we want to see a healthier world, population and animal kingdom, we have to choose what we support more wisely.

The modern-day food industry seems to pay no attention to health. Thankfully, global consciousness is shifting in several ways including how we live as humans, view our health, our economy, education, politics, and the environment. You could say that humanity is going through one MASSIVE change.

Today, billions of animals in the United States alone are raised, tortured, and slaughtered for human consumption. This reckless production and consumption, in turn, has created enormous environmental and health problems that continue to accelerate. That being said, awareness on this issue (food) in particular, has come along way. We are seeing changes in the food guide, a shift towards plant-based diets, and more corporations catering to new choices people are making around food and health. This is a good thing!

One common trend helping to create change is the continues ‘bad press’ unhealthy players in the food industry are getting.

The latest news to come out regarding food quality within fast food comes from a report recently released by six major consumer and environmental groups. They graded America’s 25 largest burger chains and their use of antibiotics in their beef supply.

22 popular fast food restaurants completely failed, including giants like McDonald’s, Burger King, Sonic and In-N-Out.  The evaluation looked at each chain’s antibiotic use policies and whether these policies were truly implemented in their product. They also examined how transparent the chains were with their antibiotic use.

The Problem With Antibiotic Use

Antibiotics given to farm animals can lead to antibiotic-resistant bacteria, among other things. This is actually one of the top threats to global public health, which is exemplified by the fact that each year, more than 2 million Americans alone suffer from these infections.

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In September 1999, Albrecht and Schutte published “Homeopathy Versus Antibiotics in Metaphylaxis of Infectious Diseases: A Clinical Study in Pig Fattening and Its Significance to Consumers” in Alternative Therapies. The study compared outcomes for four randomly assigned groups of pigs that were given placebo, homeopathic treatment, a standard blend of antibiotics and other conventional drugs in a routine low prophylactic dose, or conventional drugs in a high therapeutic dose.

There were 1440 pigs involved in the study, which took place at an intensive livestock farm in Germany. The primary outcome measured was the incidence of respiratory disease, a common problem for pigs on such farms.

The results were astounding.

Homeopathic treatment was far superior to prophylactic doses of antibiotics in preventing respiratory disease. The prophylactic antibiotic treatment made it only 11 percent less likely (than placebo) that the pigs would become sick. But homeopathic remedies made it 40 percent less likely. When the antibiotics were raised to therapeutic levels, meaning a level that is only given when people or an animal was sick, it became 70 percent less likely that the pigs would become diseased.

The significance of this is that homeopathic treatment on animals would already be better than routine antibiotic treatment. When an animal is actually sick, the farmer would then have the choice to increase homeopathic or use a legitimately high-level dose of antibiotics. This, significantly less cost and significantly fewer antibiotics in meat.

The List

The Takeaway

Simple, avoid fast food. There are many out there who seem to believe that people will always consume this food, but we fail to recognize that it’s not just our choice. The “food” these corporations offer is highly addictive to people, and that’s done on purpose.

If we can connect with caring about our health, quality of life and well-being of animals and the planet, these are places you must steer away from. In general, eating meat does not support the health and wellbeing of us nor animals, but this is a choice we each make.

Recommended Articles

A Native American Perspective On Veganism

Plant-Based Protein VS. Protein From Meat: Which One Is Better For You? 

Doctor Explains How Humans Have A “Strict” Vegan Physiology

Vegan Activist James Aspey Beautifully Shows How To Consciously Inform People

9 Things That Happen When You Stop Eating Meat

Internal Medicine Physician Shares What Happens To Your Body When You Stop Eating Meat

Animals – Why Do We Love One But Eat The Other? 

The Heart Disease Rates of Meat-Eaters Versus Vegetarians & Vegans

Were Those Who Roamed The Earth Before US Nearly All Vegetarian?

A Quick Important Notice:

The demand for Collective Evolution's content is bigger than ever, except ad agencies and social media keep cutting our revenues. This is making it hard for us to continue.

In order to stay truly independent, we need your help. We are not going to put up paywalls on this website, as we want to get our info out far and wide. For as little as $3 a month, you can help keep CE alive!

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Epigenetic Memories Are Passed Down 14 Successive Generations, Game-Changing Research Reveals

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In Brief

  • The Facts:

    It's amazing how much information can be passed on to our offspring. Scientist have discovered that our DNA has memories, and these can also be passed down. We are talking about thoughts, feelings, emotions and perceptions.

  • Reflect On:

    Biological changes are shaped by our environment, as well as our thoughts, feelings, emotions and reaction to that environment. Our DNA can be changed with belief, the placebo is a great example. Thoughts feelings and emotions are huge in biology.

This article was written by the Greenmedinfo research group, from Greenmedinfo.com. Posted here with permission.

Until recently, it was believed that our genes dictate our destiny. That we are slated for the diseases that will ultimately beset us based upon the pre-wired indecipherable code written in stone in our genetic material. The burgeoning field of epigenetics, however, is overturning these tenets, and ushering in a school of thought where nurture, not nature, is seen to be the predominant influence when it comes to genetic expression and our freedom from or affliction by chronic disease.

Epigenetics: The Demise of Biological Determinism

Epigenetics, or the study of the physiological mechanisms that silence or activate genes, encompasses processes which alter gene function without changing the sequence of nucleotide base pairs in our DNA. Translated literally to mean “in addition to changes in genetic sequence,” epigenetics includes processes such as methylation, acetylation, phosphorylation, sumolyation, and ubiquitylation which can be transmitted to daughter cells upon cell division (1). Methylation, for example, is the attachment of simple methyl group tags to DNA molecules, which can repress transcription of a gene when it occurs in the region of a gene promoter. This simple methyl group, or a carbon bound to three hydrogen molecules, effectively turns the gene off.

Post-translational modifications of histone proteins is another epigenetic process. Histones help to package and condense the DNA double helix into the cell nucleus in a complex called chromatin, which can be modified by enzymes, acetyl groups, and forms of RNA called small interfering RNAs and microRNAs (1). These chemical modifications of chromatin influence its three-dimensional structure, which in turn governs its accessibility for DNA transcription and dictates whether genes are expressed or not.

We inherit one allele, or variant, of each gene from our mother and the other from our father. If the result of epigenetic processes is imprinting, a phenomenon where one of the two alleles of a gene pair is turned off, this can generate a deleterious health outcome if the expressed allele is defective or increases our susceptibility to infections or toxicants (1). Studies link cancers of nearly all types, neurobehavioral and cognitive dysfunction, respiratory illnessesautoimmune disorders, reproductive anomalies, and cardiovascular disease to epigenetic mechanisms (1). For example, the cardiac antiarrhythmic drug procainamide and the antihypertensive agent hydralazine can cause lupus in some people by causing aberrant patterns of DNA methylation and disrupting signalling pathways (1).

Genes Load the Gun, Environment Pulls the Trigger

Pharmaceuticals, however, are not the only agents that can induce epigenetic disturbances. Whether you were born via vaginal birth or Cesarean section, breastfed or bottle-fed, raised with a pet in the house, or infected with certain childhood illnesses all influence your epigenetic expression. Whether you are sedentary, pray, smoke, mediate, do yoga, have an extensive network of social support or are alienated from your community—all of your lifestyle choices play into your risk for disease operating through mechanisms of epigenetics.

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In fact, the Centers for Disease Control (CDC) states that genetics account for only 10% of disease, with the remaining 90% owing to environmental variables (2). An article published in the Public Library of Science One (PLoS One) entitled “Genetic factors are not the major causes of chronic diseases” echoes these claims, citing that chronic disease is only 16.4% genetic, and 84.6% environmental (3). These concepts make sense in light of research on the exposome, the cumulative measure of all the environmental insults an individual incurs during their life course that determines susceptibility to disease (4)

In delineating the totality of exposures to which an individual is subjected over their lifetime, the exposome can be subdivided into three overlapping and intertwined domains. One segment of the exposome called the internal environment is comprised of processes innate to the body which impinge on the cellular milieu. This encompasses hormones and other cellular messengers, oxidative stress, inflammation, lipid peroxidation, bodily morphology, the gut microbiotaaging and biochemical stress (5).

Another portion of the exposome, the specific external environment, consists of exposures including pathogens, radiation, chemical contaminants and pollutants, and medical interventions, as well as dietary, lifestyle, and occupational elements (5). At an even broader sociocultural and ecological level is the segment of the exposome called the general external environment, which may circumscribe factors such as psychological stress, socioeconomic status, geopolitical variables, educational attainment, urban or rural residence, and climate (5).

Transgenerational Inheritance of Epigenetic Change: Endocrine Disruptors Trigger Infertility in Future Generations

Scientists formerly speculated that epigenetic changes disappear with each new generation during gametogenesis, the formation of sperm and ovum, and after fertilization. However, this theory was first challenged by research published in the journal Science which demonstrated that transient exposure of pregnant rats to the insecticide methoxychlor, an estrogenic compound, or the fungicide vinclozolin, an antiandrogenic compound, resulted in increased incidence of male infertility and decreased sperm production and viability in 90% of the males of four subsequent generations that were tracked (1).

Most notably, these reproductive effects were associated with derangements in DNA methylation patterns in the germ line, suggesting that epigenetic changes are passed on to future generations. The authors concluded, “The ability of an environmental factor (for example, endocrine disruptor) to reprogram the germ line and to promote a transgenerational disease state has significant implications for evolutionary biology and disease etiology” (6, p. 1466). This may suggest that the endocrine-disrupting, fragrance-laden personal care products and commercial cleaning supplies to which we are all exposed may trigger fertility problems in multiple future generations.

Transgenerational Inheritance of Traumatic Episodes: Parental Experience Shapes Traits of Offspring

In addition, traumatic experiences may be transmitted to future generations via epigenetics as a way to inform progeny about salient information needed for their survival (7). In one study, researchers wafted the cherry-like chemical acetophenone into the chambers of mice while administering electric shocks, conditioning the mice to fear the scent (7). This reaction was passed onto two successive generations, which shuddered significantly more in the presence of acetophenone despite never having encountered it compared to descendants of mice that had not received this conditioning (7).

The study suggests that certain characteristics of the parental sensory environment experienced before conception can remodel the sensory nervous system and neuroanatomy in subsequently conceived generations (7). Alterations in brain structures that process olfactory stimuli were observed, as well as enhanced representation of the receptor that perceives the odor compared to control mice and their progeny (7). These changes were conveyed by epigenetic mechanisms, as illustrated by evidence that the acetophenone-sensing genes in fearful mice were hypomethylated, which may have enhanced expression of odorant-receptor genes during development leading to acetophenone sensitivity (7).

The Human Experience of Famine and Tragedy Spans Generations

The mouse study, which illustrates how germ cells (egg and sperm) exhibit dynamic plasticity and adaptability in response to environmental signals, is mirrored by human studies. For instance, exposures to certain stressors such as starvation during the gestational period are associated with poor health outcomes for offspring. Women who undergo famine before conception of her offspring have been demonstrated to give birth to children with lower self-reported mental health and quality of life, for example (8).

Studies similarly highlight that, “Maternal famine exposure around the time of conception has been related to prevalence of major affective disorders, antisocial personality disorders, schizophrenia, decreased intracranial volume, and congenital abnormalities of the central nervous system” (8). Gestational exposure to the Dutch Famine of the mid-twentieth century is also associated with lower perceived health (9), as well as enhanced incidence of cardiovascular disease, hypertension, and obesity in offspring (8). Maternal undernourishment during pregnancy leads to neonatal adiposity, which is a predictor of future obesity (10), in the grandchildren (11).

The impact of epigenetics is also exemplified by research on the intergenerational effects of trauma, which illuminates that descendants of people who survived the Holocaust exhibit abnormal stresshormone profiles, and low cortisol production in particular (12). Because of their impaired cortisol response and altered stress reactivity, children of Holocaust survivors are often at enhanced risk for post-traumatic stress disorder (PTSD), anxiety, and depression (13).

Intrauterine exposure to maternal stress in the form of intimate partner violence during pregnancy can also lead to changes in the methylation status of the glucocorticoid receptor (GR) of their adolescent offspring (14). These studies suggest that an individual’s experience of trauma can predispose their descendants to mental illness, behavioral problems, and psychological abnormalities due to “transgenerational epigenetic programming of genes operating in the hypothalamic-pituitary-adrenal axis,” a complex set of interactions among endocrine glands which determine stress response and resilience (14).

Body Cells Pass Genetic Information Directly Into Sperm Cells

Not only that, but studies are illuminating that genetic information can be transferred through the germ line cells of a species in real time. These paradigm-shifting findings overturn conventional logic which postulates that genetic change occurs over the protracted time scale of hundreds of thousands or even millions of years. In a relatively recent study, exosomes were found to be the medium through which information was transferred from somatic cells to gametes.

This experiment entailed xenotransplantation, a process where living cells from one species are grafted into a recipient of another species. Specifically, human melanoma tumor cells genetically engineered to express genes for a fluorescent tracer enzyme called EGFP-encoding plasmid were transplanted into mice. The experimenters found that information-containing molecules containing the EGFP tracer were released into the animals’ blood (15). Exosomes, or “specialized membranous nano-sized vesicles derived from endocytic compartments that are released by many cell types” were found among the EGFP trackable molecules (16, p. 447).

Exosomes, which are synthesized by all plant and animal cells, contain distinct protein repertoires and are created when inward budding occurs from the membrane of multivesicular bodies (MVBs), a type of organelle that serves as a membrane-bound sorting compartment within eukaryotic cells (16). Exosomes contain microRNA (miRNA) and small RNA, types of non-coding RNA involved in regulating gene expression (16). In this study, exosomes delivered RNAs to mature sperm cells (spermatozoa) and remained stored there (15).

The researchers highlight that this kind of RNA can behave as a “transgenerational determinant of inheritable epigenetic variations and that spermatozoal RNA can carry and deliver information that cause phenotypic variations in the progeny” (15). In other words, the RNA carried to sperm cells by exosomes can preside over gene expression in a way that changes the observable traits and disease risk of the offspring as well as its morphology, development, and physiology.

This study was the first to elucidate RNA-mediated transfer of information from somatic to germ cells, which fundamentally overturns what is known as the Weisman barrier, a principle which states that the movement of hereditary information from genes to body cells is unidirectional, and that the information transmitted by egg and sperm to future generations remains independent of somatic cells and parental experience (15).

Further, this may bear implications for cancer risk, as exosomes contain vast amounts of genetic information which can be source of lateral gene transfer (17) and are abundantly liberated from tumor cells (18). This can be reconciled with the fact that exosome-resembling vesicles have been observed in various mammals (15), including humans, in close proximity to sperm in anatomical structures such as the epididymis as well as in seminal fluid (19). These exosomes may thereafter be propagated to future generations with fertilization and augment cancer risk in the offspring (20).

The researchers concluded that sperm cells can act as the final repositories of somatic cell-derived information, which suggests that epigenetic insults to our body cells can be relayed to future generations. This notion is confirmatory of the evolutionary theory of “soft inheritance” proposed by French naturalist Jean-Baptiste Lamarck, whereby characteristics acquired over the life of an organism are transmitted to offspring, a concept which modern genetics previously rejected before the epigenetics arrived on the scene. In this way, the sperm are able to spontaneously assimilate exogenous DNA and RNA molecules, behaving both as vector of their native genome and of extrachromosomal foreign genetic material which is “then delivered to oocytes at fertilization with the ensuing generation of phenotypically modified animals” (15).

Epigenetic Changes Endure Longer Than Ever Predicted

In a recent study, nematode worms were manipulated to harbor a transgene for a fluorescent protein, which made the worms glow under ultraviolet light when the gene was activated (21). When the worms were incubated under the ambient temperature of 20° Celsius (68° Fahrenheit), negligible glowing was observed, indicating low activity of the transgene (21). However, transferring the worms to a warmer climate of 25°C (77° F) stimulated expression of the gene, as the worms glowed brightly (21).

In addition, this temperature-induced alteration in gene expression was found to persist for at least 14 generations, representing the preservation of epigenetic memories of environmental change across an unprecedented number of generations (21). In other words, the worms transmitted memories of past environmental conditions to their descendants, through the vehicle of epigenetic change, as a way to prepare their offspring for prevailing environmental conditions and ensure their survivability.

Future Directions: Where Do We Go From Here?

Taken cumulatively, the aforementioned research challenges traditional Mendelian laws of genetics, which postulate that genetic inheritance occurs exclusively through sexual reproduction and that traits are passed to offspring through the chromosomes contained in germ line cells, and never through somatic (bodily) cells. Effectively, this proves the existence of non-Mendelian transgenerational inheritance, where traits separate from chromosomal genes are transmitted to progeny, resulting in persistent phenotypes that endure across generations (22).

This research imparts new meaning to the principle of seven generation stewardship taught by Native Americans, which mandates that we consider the welfare of seven generations to come in each of our decisions. Not only should we embody this approach in practices of environmental sustainability, but we would be wise to consider how the conditions to which we subject our bodies—the pollution and toxicants which permeate the landscape and pervade our bodies, the nutrient-devoid soil that engenders micronutrient-poor food, the disruptions to our circadian rhythm due to the ubiquity of electronic devices, our divorce from nature and the demise of our tribal affiliations—may translate into ill health effects and diminished quality of life for a previously unfathomed number of subsequent generations.

Hazards of modern agriculture, the industrial revolution, and contemporary living are the “known or suspected drivers behind epigenetic processes…including heavy metals, pesticides, diesel exhaust, tobacco smoke, polycyclic aromatic hydrocarbons, hormones, radioactivity, viruses, bacteria, and basic nutrients” (1, p. A160). Serendipitously, however, many inputs such as exercise, mindfulness, and bioactive components in fruits and vegetables such as sulforaphane in cruciferous vegetables, resveratrol from red grapes, genistein from soy, diallyl sulphide from garlic, curcumin from turmeric, betaine from beets, and green tea catechin can favorably modify epigenetic phenomena “either by directly inhibiting enzymes that catalyze DNA methylation or histone modifications, or by altering the availability of substrates necessary for those enzymatic reactions” (23, p. 8).

This quintessentially underscores that the air we breathe, the food we eat, the thoughts we allow, the toxins to which we are exposed, and the experiences we undergo may persevere in our descendants and remain in our progeny long after we are gone. We must be cognizant of the effects of our actions, as they elicit a ripple effect through the proverbial sands of time.

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References

1. Weinhold, B. (2006). Epigenetics: The Science of Change. Environmental Health Perspectives, 114(3), A160-A167.

2. Centers for Disease Control and Prevention. (2014). Exposome and Exposomics. Retrieved from https://www.cdc.gov/niosh/topics/exposome/

3. Rappaport, S.M. (2016). Genetic factors are not the major causes of chronic diseases. PLoS One, 11(4), e0154387.

4. Vrijheid, M. (2014). The exposome: a new paradigm to study the impact of environment on health. Thorax, 69(9), 876-878. doi: 10.1136/thoraxjnl-2013-204949.

5. Wild, C.P. (2012). The exposome: from concept to utility. International Journal of Epidemiology, 41, 24–32. doi:10.1093/ije/dyr236

6. Anway, M.D. et al. (2005). Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science, 308(5727), 1466-1469.

7. Dias, B.G., & Ressler, K.J. (2014). Parental olfactory experience influences behavior and neural structure in subsequent generations. Nature Neuroscience, 17(1), 89-98.

8. Stein, A.D. et al. (2009). Maternal exposure to the Dutch Famine before conception and during pregnancy: quality of life and depressive symptoms in adult offspring. Epidemiology, 20(6), doi:  10.1097/EDE.0b013e3181b5f227.

9. Roseboom, T.J. et al. (2003). Perceived health of adults after prenatal exposure to the Dutch famine. Paediatrics Perinatal Epidemiology, 17, 391–397.

10. Badon, S.E. et al. (2014). Gestational Weight Gain and Neonatal Adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Study-North American Region. Obesity (Silver Spring), 22(7), 1731–1738.

11. Veenendaal, M.V. et al. (2013). Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine. BJOG, 120(5), 548-53. doi: 10.1111/1471-0528.

12. Yehuda, R., & Bierer, L.M. (2008). Transgenerational transmission of cortisol and PTSD risk. Progress in Brain Research, 167, 121-135.

13. Aviad-Wilcheck, Y. et al. (2013). The effects of the survival characteristics of parent Holocaust survivors on offsprings’ anxiety and depression symptoms. The Israel Journal of Psychiatry and Related Sciences, 50(3), 210-216.

14. Radke, K.M. et al. (2011). Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor. Translational Psychiatry, 1, e21. doi: 10.1038/tp.2011.21.

15. Cossetti, C. et al. (2014). Soma-to-Germline Transmission of RNA in Mice Xenografted with Human Tumour Cells: Possible Transport by Exosomes. PLoS One, https://doi.org/10.1371/journal.pone.0101629.

16. Zomer, A. et al. (2010). Exosomes: Fit to deliver small RNA. Communicative and Integrative Biology, 3(5), 447–450.

17. Balaj, L. et al. (2011) Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences. Natural Communications, 2, 180.

18. Azmi, A.S., Bao, B., & Sarkar, F.H. (2013). Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. Cancer Metastasis Review, 32, 623-643

19. Poliakov, A. et al. (2009). Structural heterogeneity and protein composition of exosomes-like vesicles (prostasomes) in human semen. Prostate, 69, 159-167.

20. Cheng, R.Y. et al. (2004) Epigenetic and gene expression changes related to transgenerational carcinogenesis. Molecular Carcinogenesis, 40, 1–11.

21. Klosin, A. et al. (2017). Transgenerational transmission of environmental information in C. elegans. Science, 356(6335).

22. Lim, J.P., & Brunet, A. (2013). Bridging the transgenerational gap with epigenetic memory. Trends in Genetics, 29(3), 176-186. doi: 10.1016/j.tig.2012.12.008

23. Choi, S.-W., & Friso, S. (2010). Epigenetics: A New Bridge between Nutrition and Health Advances in Nutrition: An International Review Journal, 1(1), 8-16. doi:10.3945/an.110.1004.

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Awareness

Brain Imaging Shows Autistic Brains Contain HIGH Amounts of Aluminum

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In Brief

  • The Facts:

    A study published early in 2018 identified very high amounts of aluminum lodged in the brains of multiple people with autism.

  • Reflect On:

    We know little about where the heavy metals used as adjuvants in vaccines end up in the body. We now know that injected aluminum doesn't exit the body like aluminum intake from other sources. When injected, it ends up in the brain.

A study published earlier in 2018 should have made headlines everywhere, as it discovered historically high amounts of aluminum in autistic brains. The study was conducted by some of the worlds leading scientists in the field.

Five people were used in the study, four males and one female, all between the ages of 14-50. Each of their brains contained unsafe and high amounts of aluminum compared to patients with other diseases where high brain aluminum content is common, like Alzheimer’s disease, for example.

Of course, this caused people to downplay the study, citing a low sample group, but that’s not entirely a valid argument given the reason why this study was conducted. As cited in the study above, recent studies on animals, published within the past few years, have supported a strong connection between aluminum, and aluminum adjuvants used in human vaccinations, and Autism Spectrum Disorder (ASD.)

Studies have also shown that injected aluminum does not exit the body, and can be detected inside the brain even a year after injection. That being said, when we take aluminum in from sources such as food, the body does a great job of getting it out, but there is a threshold. It’s important to acknowledge that the aluminum found in the brain, could be due to the presence of aluminum adjuvants in vaccines. This latest study also identified the location of aluminum in these tissues, and where they end up. This particular study was done on humans, which builds upon, and still supports, the findings of the animal studies.

This is also important because the majority of studies that previously examined human exposure to aluminum have only used hair, blood and urine samples. The study also makes a clear statement regarding vaccines, stating that “Paediatric vaccines that include an aluminum adjuvant are an indirect measure of infant exposure to aluminum and their burgeoning use has been directly correlated with increasing prevalence of ASD.”

 Aluminum, in this case, was found in all four lobes of the brain.

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The aluminum content of brain tissues from donors with a diagnosis of ASD was extremely high (Table 1). While there was significant inter-tissue, inter-lobe and inter-subject variability the mean aluminium content for each lobe across all 5 individuals was towards the higher end of all previous (historical) measurements of brain aluminium content, including iatrogenic disorders such as dialysisencephalopathy[13][15][16][17][18][19]. All 4 male donors had significantly higher concentrations of brain aluminum than the single female donor. We recorded some of the highest values for brain aluminum content ever measured in healthy or diseased tissues in these male ASD donors

We Know, And Have Known, Aluminum Is Not Safe, Yet We Ignore It

When we talk about the ‘safe’ amount of aluminum here, there is no such thing. Aluminum is extremely toxic to any biological process, it’s not meant for us which is why it stayed deep within the Earth until we took it out. It has no place within us, and that’s simply due to the fact that it causes nothing but havoc. This makes it odd that we would put them in vaccinations despite the fact that for 100 years there has been no appropriate safety testing.

Aluminum is an experimentally demonstrated neurotoxin and the most commonly used vaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants, medical science’s understanding about their mechanisms of action is still remarkably poor. There is also a concerning scarcity of data on toxicology and pharmacokinetics of these compounds. In spite of this, the notion that aluminum in vaccines is safe appears to be widely accepted. Experimental research, however, clearly shows that aluminum adjuvants have a potential to induce serious immunological disorders in humans.

The quote above comes from a study published in 2011, it’s 2018 now and we’ve come along way in our understanding. We are starting to see even more research confirming the statement above.

Almost every study you read regarding previous studies on aluminum adjuvants within vaccines emphasized how the nature of its bioaccumulation is unknown, and a serious matter. We now know that it goes throughout the body, into distant organs eventually ends up in the brain.

Another fairly recent study from 2015 points out:

Evidence that aluminum-coated particles phagocytozed in the injected muscle and its draining lymph notes can disseminate within phagocytes throughout the body and slowly accumulate in the brain further suggests that alum safety should be evaluated in the long term.(source)

The pictures below come from the recent 2018 study and show ‘bright spots’ that indicate heavy metals in the brain.

 

The more recent study discussed in this article is adding to that evidence. Below you can watch one of the most recent interviews with Dr. Eric Exly, one of the world’s foremost leading authors on the subject, and one of the authors of this most recent study. He is a Biologist (University of Stirling) with a Ph.D. in the ecotoxicology of aluminum. You can read more about his background here.

Take Away

People need to understand that despite media bullying, it’s ok to question vaccine safety, and there is plenty of reason to. There are many concerns, and heavy metals are one of them. In fact, the persistence and abundant presence of heavy metals in our environment, foods and medications is a concern, one that has been the clear cause for a variety of health ailments, yet it’s one that’s hardly addressed by the medical industry.

You can detox from this with items such as Spirulina, and waters that contain a high Silica content. There are studies that show various methods of detoxing can be used to get this lodged aluminum, or some of it, out of your body, organs and brain. This is where educating yourself regarding the medicinal value of food and nutrition is a key Perhaps this can be a motivation to better your diet, especially if you have, are someone, or know someone with an ASD diagnosis.

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