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Why The Law Forbids The Medicinal Use of Natural Substances

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In Brief

  • The Facts:

    This article was written by Sayer Ji, founder of Greenmedinfo.com where this article first appeared. Posted here with permission.

  • Reflect On:

    Why is nature legal? Why do we always get the medication that can be patented? Why are these medications the only ones doctors are allowed to recommend?

According to the FDA’s legal definition, a drug is anything that “diagnoses, cures, mitigates, treats, or prevents a disease.”

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The problem with this definition is that there are numerous substances, as readily available and benign as found on our spice racks, which have been proven by countless millennia of human experience to mitigate, prevent and in some cases cure disease, and which cannot be called drugs according to the FDA.

How can this be? Well, the FDA has assumed for itself Godlike power, requiring that its official approval be obtained before any substance can legally be used in the prevention and treatment of disease.

The FDA’s legal-regulatory control therefore is totalitarian and Napoleonic in construct; what it does not explicitly permit as a medicine is implicitly forbidden.

Historically the FDA has required new drugs undergo expensive and elaborate multi-phased clinical trials, which are out of the grasp of any ordinary interest who might want to demonstrate the efficacy of a non-patentable (and therefore unprofitable) herb, food or spice.

The average out-of-pocket cost for obtaining a new drug approval is 2.6 billion dollars,[1] and therefore an investor putting capital into bringing to market a substance that does not lend itself to market exclusivity and therefore cannot produce a return on investment, is committing economic suicide, if not also breaking the law. The investor actually has a legally-binding fiduciary responsibility to its shareholders to make a profit. And therefore, capital will not flow into any would-be commodity that can be produced or obtained with ease, including most things that grow freely on this Earth.

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It is an interesting footnote in history that shortly after the Declaration of Independence,  Congress declared that natural substances, e.g. water or salt, were God’s gift to mankind and that therefore products of nature should be limited in their patent protection. While this was a noble declaration, it has actually been used against those whose rights it would protect. It has forced private interests to synthetically alter natural substances — for instance the burgeoning biotech field of recombinant DNA technology, i.e. genetically modified organisms (GMOs) — for the sole reason that it guarantees them ownership/patent rights.

In fact, a medical system that, due to its corporate structure, legally requires it make a profit threatens to destroy and/or incriminate itself if non-patented, non-profitable natural substances or therapies are employed. It also results in so much collateral damage to those it purports to serve that it could rightly be called a modern form ofhuman sacrifice.

As a result, instead of choosing prospective medicines logically: because they work, are easily accessible, and safe, billions of dollars flow in the exact opposite direction, capitalizing only those substances which are unnatural, and therefore while proprietary are almost invariably unsafe and less effective, and whose access and administration can be intensively controlled.

Has The Attempt To Co-opt Medicine Through the Drug-Based Model Undone Itself? 

And yet, there is a silver lining to the story. Due to the fact that our bodies are ultimately constructed from the natural things (food, air and water), and obey very strict natural laws such as the well-known principle of chirality (handedness) – the fact that all amino acids in our body turn a beam of polarized light in the left-handed direction (L-lysine) and sugars to the right-handed direction (D-ribose)– one cannot simply create biologically active, synthetic drugs arbitrarily, as a mistake in handedness (or similar property) could be fatal (this is the lethal problem with ibuprofen). Nature, therefore, still provides an elegant biomolecular architecture of irreproducible intelligence and complexity, from which synthetic analogs are modeled and/or derivatives are spun.

As a result, billions of dollars of drug industry and government money (i.e. tax payer money) flow into finding lead compounds for drug development.  Nature is put on the rack, if you will, and her secrets teased from her through innumerable animal and test tube experiments, in order to find compounds that can then be converted into synthetic, patented drugs.

Inadvertently, some of the very same companies and interests which require that natural substances not receive the same drug-approval status as synthetic ones, are funding research that prove basic vitaminsfoods and spices are as effective or more effective – and usually much safer – than the drugs  they are developing to replace or supplant them.

This means that tens of thousands of studies do exist showing that natural substances may prevent and/or treat disease, at least in the in vitro (test tube) and animal models. These results often confirm traditional uses in Ayurvedic, Chinese and other traditional systems of medicine, and therefore may be compelling enough for individuals or healthcare practitioners to use the information to inform their treatment decisions.

The Case For Curcumin In the Prevention and Treatment of Disease

The government biomedical and life sciences database known as Medline contains over 28 million published study citations, and is accessible to search through engines such as Pubmed.gov.  3.6 million of them contain reference to cancer.  250,000 of them remain after applying the “Complementary Medicine” filter.   There are 1,042 topics related to cancer which can be found indexed on the GreenMedInfo.com database, referencing 838 natural substances of potential value.

Turmeric, and particularly its polyphenolic constituent known as curcumin, which gives the spice its golden hue, is one of the most extensively studied natural compounds of all time, with11,700 references to it on the National Library of Medicine’s bibliographic database known as Medline [as of 6.01.2018]. And yet, despite having been shown to have therapeutic value in over 800 disease states in animal and in vitro studies, it still has not been the subject of extensive human clinical research – for the reasons stated above.

GreenMedInfo.com, an open source natural medicine database, has indexed curcumin’s anti-cancer properties in over 50 cancers, with the top 10 most cancers researched in association with curcumin listed below.

Source: http://www.greenmedinfo.com/substance/curcumin

As one can see curcumin holds great promise. It has been repeatedly demonstrated to possess simultaneously both chemoprotective/chemosensitizing and radioprotective/radiosensitizing properties, meaning it is capable of reducing the adverse effects on healthy cells caused by chemotherapy and radiotherapy, as well as enhance the cancer-killing properties of these conventional therapies. It also has an exceptionally high margin of safety, at least an order of magnitude greater than commonly used conventional chemotherapy agents such as 5-fluoruracil.[2] Given these facts curcumin, at the very least, should be considered an ideal candidate for use as an adjuvant in integrative cancer care, and perhaps as a first-line treatment alternative to conventional chemo-agents.

To learn more about our Turmeric/Curcumin Research, watch my latest update:

Link To Original Article

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References

[1] https://cen.acs.org/articles/92/web/2014/11/Tufts-Study-Finds-Big-Rise.html

[2] Curcumin’s LD50 (lethal dose, 50%) in mice is at least 2,000 mg/kg, versus 5-fluorouracil 115 mg/kg, or


Sayer Ji is founder of Greenmedinfo.com, a reviewer at the International Journal of Human Nutrition and Functional Medicine, Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of the National Health Federation, Steering Committee Member of the Global Non-GMO Foundation.

 

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Awareness

Studies Show What A Whole Foods Vegan Diet Does For People With Diabetes

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In Brief

  • The Facts:

    Multiple studies have shown that a whole foods, plant-based diet can help manage, prevent, and, in some cases, even reverse diabetes.

  • Reflect On:

    Why is dietary intervention not a priority of conventional doctors? Especially when it can be much more beneficial to the patient than medication?

Food truly is medicine, and nutrition is a great way to combat multiple diseases. What’s extremely confusing is why so many doctors still choose to prescribe medication first, without considering the power of nutrition. Many doctors are not even aware of the power of nutrition and its ability to heal diseases, and this is probably because they know next to nothing about it given that they learn nothing about it in medical school.

However, things are changing. There are an abundance of doctors who are not prescribing medication when it’s not needed, and instead prescribing a proper diet. Many of them are starting to educate themselves using the literature and science surrounding nutrition. It’s not only doctors, but patients are choosing to self educate themselves now as well.

When it comes to the medical industry, self education is important, given the fact that “The medical profession is being bought by the pharmaceutical industry, not only in terms of the practice of medicine, but also in terms of teaching and research. The academic institutions of this country are allowing themselves to be the paid agents of the pharmaceutical industry.”   Arnold Seymour Relman (1923-2014), Harvard Professor of Medicine and Former Editor-in-Chief of the New England Medical Journal (source)

Not long ago, Dr. Asseem Malhotra, a well-known Doctor in Britain, had some choice words to say in front of the European Parliament about modern-day medical education and the overall knowledge doctors possess. He’s one of many who continues to emerge and speak out. You can read more about that here.

When it comes to type 2 diabetes, it’s one of the diseases that can easily be managed with a proper diet. The undue influence the pharmaceutical industry has on the medical industry and doctors’ lack of understanding of nutrition is why, I believe, more than 370 million people around the world suffer from diabetes, and approximately 100 million Americans have it or are likely to get it.

It’s firmly established in scientific literature and quite clear now that moving to a whole-food, plant-based diet can drastically reduce the symptoms of type 1 diabetes and can even help manage, or in many cases completely reverse, type 2 diabetes and pre-diabetes. Giving up animal products and processed foods helps as well, and there is an abundance of research that shows this.

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Perhaps one of the most important pieces of evidence is the fact that there are real life success stories. Forks over Knives has a plethora of examples and real-life case studies that support the notion that eliminating animal products and following a healthy, whole-foods diet can make it easier to live with diabetes.

In 2016, Harvard T.H. Chan School of Public Health published a study that showed plant-based diets can lower the risk of type 2 diabetes by a third. This involves simply switching out animal products for plant-based alternatives. A whole-foods, plant-based diet is rich in beneficial dietary fiber, antioxidants, and micronutrients, and low in saturated fats. This is excellent for overall health outcomes, whether they’re related to diabetes or not.

Multiple studies have shown that red and processed meats (also recently linked to cancer by the WHO), as well as animal protein in general, increase the risk of type 2 diabetes. In omnivore populations, the risk of diabetes is doubled compared with vegans. Another study found that eating meat once a week or more over a 17-year period increased the risk of diabetes by a startling 74%. A follow up study was conducted and found that increasing red meat intake by more than just half a serving per day was closely associated with an almost 50% increased risk of contracting diabetes over four years.

Removing animal products and shifting to a diet consisting of whole and minimally processed plant foods can reduce the problems created by type 1 and type 1.5 autoimmune diabetes big time. Although there’s no cure for this type of diabetes, the right diet has plenty of benefits. Cyrus Khambatta, PhDwrites that following a low-fat, whole-foods plant-based lifestyle can:

  • Boost insulin sensitivity and reduce insulin use by more than 40 percent after six months.
  • Lead to more predictable blood glucose, making it easier to manage diabetes.
  • Increase blood flow to tissues in the body and reduce the likelihood of diabetes-related nerve damage.
  • Reduce the burden on the kidneys, decreasing the chances of getting kidney disease.

People have also reversed type 2 diabetes with a plant-based diet and fasting.

For more on that you can refer to the article linked below:

The Complete Guide To Fasting & Reversing Type 2 Diabetes: A Special Interview With Dr. Jason Fung.

Here are some other related articles you might be interested in as well:

9 Things That Happen When You Stop Eating Meat

Internal Medicine Physician Shares What Happens To Your Body When You Stop Eating Meat 

Plant-Based Protein VS. Protein From Meat: Which One Is Better For Your Body

Scientist: Milk From Cows Has “The Most Relevant Carcinogen Ever Identified” & “Turns on Cancer”

Scientist Explains How Cow’s Milk Leeches Calcium From Your Bones & Makes Them Weaker

Studies Show What Happens To Your Heart When You Go Vegan or Vegetarian

The Takeaway

The takeaway here is to recognize that a whole foods, plant-based diet can be life changing. There are a number of studies that have emerged and continue to emerge showing this, while many more show a strong connection between various diseases and eating meat. It makes one ponder, are humans even designed/supposed to eat meat, or has this simply been the tactic of clever marketing by the big food industry? Something to think about.

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Awareness

Research Reveals How Sugar CAUSES Cancer

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In Brief

  • The Facts:

    This article was written by Sayer Ji, Founder of Greenmedinfo.com where it first originally appeared. Posted here with permission.

  • Reflect On:

    The average American consumes their body weight annually in this cancer-causing substance, and yet hospitals freely feed it to their cancer patients, seemingly oblivious to the harm it does.

Hospitals feed cancer patients sugar and high carbohydrate diets for a simple reason: they are abysmally ignorant of the role of nutrition in health and disease — hence their burgeoning growth, packed rooms, and ‘return customers.’

Even though the science itself shows – at least since the mid-20’s with Otto Warburg’s cancer hypothesis — that tumors prefer to utilize sugar fermentation to produce energy rather than the much more efficient oxygen-based phosphorylation* – hospitals have actually invited corporations like McDonald’s to move into their facilities  to ‘enhance’ their patient’s gustatory experience, presumably to provide comfort and take the edge off of the painful surgery, radiation and chemo treatments erroneously proffered to them as the only reasonable ‘standard of care.’

But the times are changing, with new research requiring these medical institutions to reform their dietary strategies, at least if they wish to claim that their interventions are in fact ‘evidence-based,’ as they so often claim.

Study Reveals Sugar Doesn’t Just Feed But Causes Cancer

A groundbreaking study, uncovered by one of our volunteer researchers at Greenmedinfo, is the first of its kind to identify sugar, not only as fuel source for an already existing cancer, but as a primary driver in oncogenesis – i.e. the initiation of cancerous characteristics (phenotype) within previously healthy cells.

Published in the Journal of Clinical Investigation and titled, Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways, researchers addressed a common perception (or misperception) in the cancer research community regarding sugar’s relationship to cancer: namely, “increased glycolysis [sugar based metabolism] is frequently viewed as a consequence of oncogenic events that drive malignant cell growth and survival.”

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Contrary to this conventional view, the new study “provide[s] evidence that increased glycolytic activation itself can be an oncogenic event.”  That is to say, the activation of sugar-based metabolism in a cell – driven by both the presence of increased quantities of glucose and the increase glucose receptors on the cell membrane surface (i.e. “overexpression of a glucose transporter”) – drives cancer initiation.

Moreover, the study found that “Conversely, forced reduction of glucose uptake by breast cancer cells led to phenotypic reversion.” In other words, interfering with sugar availability and uptake to the cell causes the cancer cell to REGRESS towards its pre-cancer structure-function (phenotype).

What Are The Implications of This Research to the Diet?

What this new research indicates is that sugar – of which Americans consume an astounding 160 lbs annually (imagine: 31 five-pound bags for each of us!) – is one of the primary causes of metabolic cell changes in the body consistent with the initiation and promotion of cancer. And, the research indicates that removing it from the diet, and depriving the cells of it, could REVERSE cancer. Why is this so surprising? It’s because Americans have been lead like lambs to the slaughter to think of “prevention” as “early detection,” focusing not on identifying and removing the well known nutritional and environmental causes of cancer, rather, to spend their time, energy, and money on cause-marketing campaigns focused on “finding a cure” — as if one didn’t already exist right in front of our noses, or more aptly, on the end of our forks.

Hidden Sugar, Crouching Cancer

It has been estimated by the USDA that the average American consumes 200 lbs of grain products annually. Why is this relevant to the question of sugar in the diet? Because refined carbohydrate products – e.g. crackers, bread, pasta, cereal – are actually ‘hidden’ forms of sugar. In fact, puffed rice causes your blood to become sweeter (and presumably feeds more cancer cells sugar) than white sugar, as it is higher on the glycemic index. Adding the two figures together – annual per capita consumption of sugar and grain-based products – we get a jaw dropping 360 lbs of sugar (both overt (table sugar/high fructose corn syrup) and covert (grain carbs) annually – all of which may contribute to promoting the ideal metabolic situation of cancer cells: aerobic glycolysis.

This is one reason why the ketogenic diet – that is, a fat- and protein-focused diet devoid of carbohydrate, both in simple (sugar) and complex (grain product) form – has been found so useful in the most aggressive of cancers: including brain cancer. Once you ‘pull the rug out’ from under the sugar/carb-craving cancer cells, they are forced to either undergo programmed cell death (apoptosis) or re-differentiate back into non-cancerous phenotypes.

If It’s So Bad For Us, Why Do We Eat So Much?

One of the primary reasons why we eat sugar and carbohydrate rich diets is because they are addictive. Within minutes of consuming sugar/carbs our body goes through a neuroendocrine roller coaster. Your brain can not survive very long without glucose, the fundamental energy unit of the cell, and will ‘freak out’ if deprived of a steady stream of this ‘nutrient’ within only 2-3 minutes. The endocrine system, on the other hand, perceives the danger of high sugar – namely, glycation associated damage to protein and lipid structures within the cells of our body; think: blood caramelizing, getting sticky, and gumming up the finely tuned works – and will release hormones such as insulin, adrenaline and cortisol, in order to try to get the elevated sugar in the blood and tissues under control. Insulin forces the sugar into storage within the cell, both as glycogen and as fat, but often does its job too well, causing available glucose levels in the brain to be depleted – setting off a vicious cycle of ’emergency signals’ telling the body to release more cortisol and adrenaline to increase the levels of glucose in the blood. This, of course, will result in additional insulin production and release, causing the same cycle to be repeated over and over again.

This seemingly endless vicious cycle is responsible for the insatiable cravings a high carb/sugar diet generates – not to mention the fructose-based hedonic effects generated in the brain that modulate both opioid and dopamine receptors in the nervous system (not unlike alcohol), and the pharmacologically active peptides in many gluten-containing grains, which also drive addictive behaviors and an almost psychotic fixation on getting carbs at each meal.

No wonder we have an epidemic of cancer in a world where the Westernized diet prevails. Certainly, we do not mean to indicate that a sugar/carb-rich diet is the only cause of cancer. There are many other factors that contribute to cancer initiation and promotion, such as:

  • Chemical exposure
  • Radiation exposure
  • Chronic stress that suppresses the immune system
  • Vaccines containing hidden retroviruses and cancer causing viruses
  • Natural infection with bacteria and viruses that are cancer causing
  • Lack of sleep
  • Insufficient nutrients (lack of methyl donors such as B12, folate, and B6 will prevent the body from ‘turning off’ (methylating) cancer-promoting genes

Even though cancer is a complex, multi-factorial phenomena, with variables we can not always control, one thing we can do is control what goes into our mouth. Sugar, for instance, does not belong there if we truly want to prevent and/or treat cancer.  And don’t forget, carbohydrates that don’t taste sweet on the front end – bread, crackers, cereal – certainly convert to sugar in the body within minutes post-consumption.

In a nutshell, if you are concerned about cancer, have cancer, or would like to prevent recurrence, removing sugar and excess carbohydrates is a must. Not only is it common sense, but it is now validated by experimental research.

Additional Research

Note: another recent study found that Candida albicans (yeast) also contributes to cancer initiation and promotion. C. albicans thrives on sugar, lending additional support to the notion that sugar (consumed excessively) may be a primary driver of the cancer epidemic in those consuming the modern Western diet. For information on sugar alternatives that are not synthetic toxicants like Splenda (sucralose), read my latest article on the topic:  4 Sugar Alternatives That Won’t Poison You.


 *Note: Cancer cells prefer to ferment sugar as a form of energy even when there is sufficient oxygen available to the cells to do so; hence Warburg’s description of cancer metabolism as ‘aerobic glycolysis’ or the so-called ‘Warburg effect’

Originally published: 2017-12-04

Article udpated: 2019-07-19


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Health

Acetaminophen—Not Worth the Risk

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Acetaminophen has been around for over a century and is the most widely used drug compound in the world. In the U.S., acetaminophen (also called paracetamol or APAP) is present as an active ingredient in over 600 prescription and over-the-counter medications marketed to relieve pain or reduce fever, including Tylenol. Every week, nearly one in four Americans takes an acetaminophen-containing medication, and pediatricians routinely recommend acetaminophen as the treatment of choice for fever in children.

Despite its ubiquity, acetaminophen also has many critics. These argue that the drug’s path to prominence has been littered with errors, false assumptions and undue complacency about risks. Documented problems include life-threatening liver damage in individuals who consume acetaminophen in “excess amounts”—something that is all too easy to do, given the drug’s different aliases and the sheer number of products in which it is present—as well as cardiovascular disease and renal injury risks associated with long-term use. In the critics’ view, these and other problems make acetaminophen “one of the most dangerous compounds in medical use.”

In the U.S., roughly 500 deaths are attributable to acetaminophen each year, as well as 100,000 poison control calls, 50,000 emergency room visits and 10,000 hospitalizations. Most acetaminophen-related emergency department visits are in young children (under age 5), adolescents or young adults. The problem of accidental (or intentional) overdoses is worrisome enough, but there are other reasons to be concerned about acetaminophen use in young people—notably, the drug’s association with asthma and developmental disorders such as autismThe research linking acetaminophen to these epidemic-level chronic conditions suggests that the drug’s automatic inclusion in the childhood medicine cabinet ought to be reconsidered.

… two different studies found that acetaminophen use in the first year of life predicted asthma at age three and at six to seven years of age, respectively.

Acetaminophen and atopic conditions

Numerous studies link acetaminophen use during pregnancy with increased asthma risks in offspring. Research also points to an association between use in infancy and asthma later on. For example, two different studies found that acetaminophen use in the first year of life predicted asthma at age three and at six to seven years of age, respectively.

The associations hold true not just for asthma but also for allergies and eczema. Polish researchers reported “a significant dose-dependent increase” in the risk of asthma, allergy and eczema symptoms in three age groups who used acetaminophen in the previous 12 months: children (ages 6-7), adolescents (ages 13-14) and adults (ages 20-44). A multi-center European study found that the drug was “strongly positively associated with asthma” in 20- to 45-year-old adults taking acetaminophen on a weekly basis, compared with less frequent users.

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Taking stock of the size and consistency of the evidence, Spanish researchers—while stopping short of recommending an outright acetaminophen ban—have advocated for a significant rollback on its use:

“It is absolutely clear that the scientific literature is sending a large and consistent signal that challenges the traditional excellent safety profile of acetaminophen in children. […] A widespread, professional-based recommendation of limiting acetaminophen use to those cases in which ibuprofen cannot be administered would reduce the childhood population exposure to a minimum and would provide a good opportunity to minimize the detrimental effect of acetaminophen.”

… the authors note that the long-term effects of acetaminophen exposure on neural development have never been evaluated in humans and point out that even at very low doses, acetaminophen triggers immune system activation and oxidative stress responses—both of which are hallmarks of autism.

Autism and developmental disorders

In addition to asthma, research has linked prenatal acetaminophen use to “lower performance intelligence quotient (IQ), …autism spectrum disorder, neurodevelopmental problems (gross motor development, communication), attention-deficit/hyperactivity disorder, poorer attention and executive function, and behavioral problems in childhood.”For example, a longitudinal study that looked at language development in two-and-a-half year-olds whose mothers had taken acetaminophen during the first trimester of pregnancy found a significant association between prenatal acetaminophen use and language delays, particularly in boys. The researchers concluded, “Given…the importance of language development, these findings…would suggest that pregnant women should limit their use of this analgesic during pregnancy.”

There is especially compelling research tying acetaminophen use to autism spectrum disorder (ASD). In a 2017 study (written by a “who’s who” of autism researchers at Duke, Harvard and the University of Colorado), the authors note that “the long-term effects of acetaminophen exposure on neural development have never been evaluated in humans” and point out that even at very low doses, acetaminophen “triggers immune system activation and oxidative stress responses”—both of which are hallmarks of autism. They also assemble evidence for both prenatal and postnatal associations between acetaminophen use and neurological problems in children, including mentioning a reported link between circumcision-related acetaminophen use and increased autism prevalence.

Many parents report witnessing the onset of regressive autism following their child’s concurrent receipt of acetaminophen and vaccines.

Impaired detoxification

Studies published in 2018 propose that acetaminophen may function as an ASD risk factor in combination with other pharmaceutical and environmental toxins. For example, researchers speculate that acetaminophen magnifies the damage done by antibiotics and glyphosate because it impairs sulfate metabolism and depletes the master antioxidant—glutathione—that the body needs in order to engage in effective detoxification.

Many parents report witnessing the onset of regressive autism following their child’s concurrent receipt of acetaminophen and vaccines. However, researchers desirous of keeping the focus on acetaminophen tend to avoid discussing possible vaccine-related synergistic effects. This is somewhat puzzling, given vaccines’ aluminum content and aluminum’s capacity to impair detoxification in much the same way as acetaminophen. In fact, there are multiple mechanisms “whereby significant quantities of aluminium introduced via immunisation could produce chronic neuropathology in genetically susceptible children,” including oxidative stress, glutathione depletion and increased inflammation. The “synchronicity…between the onset of the autism epidemic and the surge in acetaminophen use” is undeniable, but so is the synchronicity between autism and the ever-expanding childhood vaccine schedule.

No more candy

For years, health providers and parents have handed out acetaminophen-containing products like candy, heedless of the compound’s documented toxicity. Johnson & Johnson, the manufacturer of Tylenol and one of the world’s largest pharmaceutical companies, has been only too happy to continue encouraging perceptions of a “favorable safety profile”; however, recurrent lawsuits and recalls and the abundant literature describing toxic outcomes suggest that it may be time for acetaminophen’s glory days to come to a close.


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