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‘Gluten Brain’: Wheat Cuts Off Blood Flow To Frontal Cortex

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In Brief

  • The Facts:

    This article was written by Sayer Ji, Founder of Greenmedinfo LLC, where it originally appeared.

  • Reflect On:

    Wheat consumption has been linked to psychiatric conditions like schizophrenia for over 60 years, but recent research indicates the mind-altering properties of this popular food are, in part, caused by it cutting off blood flow to the frontal cortex.

As far back as 1954, reports of the full or partial resolution of schizophrenia following a gluten free diet began to surface in the medical literature. I explored this remarkable phenomenon in a previous article titled, “60 Years of Research Links Gluten Grains to Schizophrenia.” While the explanation for this intriguing connection has remained focused on the disruption of the gut-brain axis and the presence in wheat of a wide range of pharmacologically active and mostly opioid receptor modulating polypeptides with glutathione-depleting properties, a new and possibly more disturbing explanation is beginning to surface: wheat consumption also cuts off blood flow to the brain.

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Starting with a 1997 case study published in the Journal of Internal Medicine involving a 33-year-old patient, with pre-existing diagnosis of ‘schizophrenic’ disorder, who first came to medical attention for severe diarrhea and weight loss (classical symptoms of gluten intolerance), brain scan technology determined that cerebral hypoperfusion (decreased blood flow to the brain) was occurring within the patient’s frontal cortex.[i] A gluten free diet resulted not only in the normalization of intestinal damage and autoantibodies, but also in the return of blood flow to the frontal cortex, and the resolution of schizophrenic symptoms.

Then, in 2004, a follow up study was performed to verify if the 1997 case study was just a fluke, or perhaps a widespread effect of untreated celiac disease. Published in the American Journal of Medicine, researchers from the Institute of Internal Medicine, Catholic University, Rome, Italy, compared 15 untreated celiac patients without neurological or psychiatric disorders other than anxiety or depression, with 15 celiac patients who were on a gluten-free diet for almost 1 year, and 24 healthy volunteers of similar sex and age. All subjects underwent cerebral single photon emission computed tomography examination.

The results were remarkable, with dramatically increased incidence of impaired brain blood flow in untreated celiac patients, reported as follows:

Of the 15 untreated celiac patients, 11 (73%) had at least one hypoperfused brain region, compared with only 1 (7%) of the 15 celiac patients on a gluten-free diet and none of the controls (P = 0.01). Cerebral perfusion was significantly lower (P <0.05) in untreated celiac patients, compared with healthy controls, in 7 of 26 brain regions. No significant differences in cerebral perfusion were found between celiac patients on a gluten-free diet and healthy controls.”

They concluded: “There is evidence of regional cerebral blood flow alteration in untreated celiac patients.”

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Discussion

So, let’s take a closer look at what cerebral (brain) hypoperfusion means.

Hypoperfusion is simply decreased blood flow through an organ. Whether it is an internal organ like the kidney, a muscle or the brain, the organ will experience lower availability of oxygen (hypoxia) and nutrients, and will therefore function at a suboptimal level.  Cerebral hypoperfusion, therefore, is decreased blood flow to the brain – an organ with extremely high energy demands, and upon which our entire consciousness depends.

Dr. David Perlmutter, author of the #1 New York Times bestselling book Grain Brain, has made great strides in introducing the concept to the world that grains adversely affect brain health. We know that the carbohydrate content of grains alone contribute to disrupting insulin-mediated glucose homeostasis within neurons, ultimately contributing to their suboptimal functioning and in some cases demise, but the discovery that wheat in particular has blood flow disrupting properties to the frontal cortex of the brain, has profound implications.

For example, it is know that the frontal lobe house the ‘executive functions of the brain, including:

  • Recognizing future consequences resulting from current actions
  • Choosing between ‘good’ and ‘bad’ actions
  • Overriding and suppressing socially unacceptable responses
  • Retaining longer term memories which are not task-based.
  • Determine similarities and differences between things or events.

If wheat consumption, through some as of yet unknown mechanism, interferes with blood flow to the brain in susceptible individuals, and as a result disrupts the executive functions of the brain, abstaining from it should be considered a reasonable precautionary behavior, assuming we wish to retain these critical functions related to morality, cognizance, and social responsibility. I explore other socio-political implications of the Western world’s several thousand year old love affaird with wheat, the ‘king of grains,’ in my essay The Dark Side of Wheat.

For additional research on the adverse health effects of wheat, read my article: Wheat: 200 Clinically Confirmed Reasons Not To Eat It or view GreenMedInfo.com’s biomedical research database on the topic: Wheat Toxicity

Also, for more information on the brain-specific harmful effects of wheat, read the following articles or watch the video:


Original article link


Additional References

[i] A De Santis, G Addolorato, A Romito, S Caputo, A Giordano, G Gambassi, C Taranto, R Manna, G Gasbarrini. Schizophrenic symptoms and SPECT abnormalities in a coeliac patient: regression after a gluten-free diet. J Intern Med. 1997 Nov ;242(5):421-3. PMID: 9408073


Sayer Ji is founder of Greenmedinfo.com, a reviewer at the International Journal of Human Nutrition and Functional Medicine, Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of the National Health Federation, Steering Committee Member of the Global Non-GMO Foundation.


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Awareness

Glyphosate & Colorectal Cancer in Young Adults

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In Brief

  • The Facts:

    This article was written by By Lyn Redwood, RN, MSN, President of Children’s Health Defense.

  • Reflect On:

    How did our federal health regulatory agencies ever approve something so dangerous and damaging to human health?

In Part I, “The Disturbing Increase in Colorectal Cancer in Young Adults,” we called attention to the steep rise in colorectal cancer incidence in young people in their twenties and thirties and discussed the risks associated with viral vaccines. In Part II, we discuss glyphosate as another plausible culprit in the colorectal cancer epidemic.

Gut bacteria play a pivotal role in shoring up brain health and overall health. This fact has become a widely acknowledged talking point in scientific circles as well as in the popular press. The reverse is also true—when diet or environmental factors produce gut dysbiosis (an imbalance of the microbes that reside in the gastrointestinal tract), the imbalance can “impact the pathologies of many diseases.”

Colorectal cancer has increased by 51% in Americans under age 50 since the mid-1990s, and researchers suggest that “early life exposures…may be contributing to the rise” in that age group. A leading hypothesis is that gut dysbiosis is playing an active part—perhaps by disrupting young people’s immune response and triggering overactivation of cell signaling proteins in the colon. Some researchers have even posited a “bidirectional self-feeding relationship” between the gut microbiome and colorectal cancer, with gut dysbiosis contributing to colorectal cancer growth and progression, and tumor growth in turn disturbing the gut microbiome.

Autism investigators have been at the forefront of research on the gut microbiome. They point to environmental toxins and antibiotic use as two influences that can shift the gut’s microbial composition in an unfavorable direction. Scientists attribute up to 85% of colorectal cancers to environmental and microbial factors. Glyphosate (the leading ingredient of Roundup) is both an herbicide and a patented antimicrobial. Could the upward trend in glyphosate usage that began roughly three decades ago have something to do, therefore, with the skyrocketing incidence of colorectal cancer in young people? Although recent court cases linking Roundup to cancer have focused mostly on other types of cancer such as non-Hodgkin’s lymphoma, the evidence that glyphosate wreaks havoc with gut bacteria has led many researchers to suspect that the answer is yes.

Glyphosate in the air and everywhere

These days, glyphosate exposure affects everyone, not just farmworkers. Newsweek reported in 2016 that the world is “awash in glyphosate,” with a fifteen-fold increase in Roundup use since the mid-1990s. American agriculture sprays glyphosate on at least 70 food crops. As a result, glyphosate residues are now rampant in the U.S. food supply, including in the processed Cheerios, Doritos and Oreos so frequently gobbled up by children and adolescents.

Studies have documented concerning levels of glyphosate in Americans’ urine and breastmilk. One study of U.S. adults found that average glyphosate levels in urine increased by a factor of thirteen over the two-decade period between 1993–1996 and 2014–2016—and seven out of ten study participants had glyphosate levels above the limits of detection. Mean levels of a glyphosate metabolite called AMPA measured approximately 36 times higher in the second time period. Moms Across America has reported high levels of glyphosate in three out of ten breastmilk samples tested.

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Glyphosate and the gut

A variety of in-progress clinical trials are exploring the link between the intestinal microbiota and colorectal cancer. Completed studies have already shown that individuals with colorectal cancer “display instability in the composition of their gut bacterial communities when compared with healthy controls” and have elevated levels of unfavorable bacterial species. Several of these species exhibit “pro-inflammatory and pro-carcinogenic properties, which could consequently have an impact on colorectal carcinogenesis.” In fact, researchers suggest that measurement of these out-of-whack bacterial populations could have “potential value as a marker of colon cancer.”

The widespread and intensive use of glyphosate has exacerbated “distortions in microbial communities.” Researchers note that:

Shifts in microbial compositions due to selective pressure by glyphosate may have contributed to the proliferation of plant and animal pathogens. …[W]e hypothesize that the selection pressure for glyphosate-resistance in bacteria could lead to shifts in microbiome composition and increases in antibiotic resistance to clinically important antimicrobial agents.

Researchers Anthony Samsel and Stephanie Seneff have written extensively about glyphosate in a series of papers elucidating “pathways to modern diseases.” They note that in animals, glyphosate “has been shown to disrupt gut bacteria…, preferentially killing beneficial forms and causing an overgrowth of pathogens.” Overgrowth of opportunistic pathogens can lead to a breakdown of the gut lining and the development of “leaky gut” syndrome. Researchers describe “the loss of gut barrier integrity” as “an early event which contributes to chronic inflammation,” and they have observed both gut dysbiosis and a dysfunctional intestinal barrier in colorectal cancer patients.

Turning a blind eye

Far from sticking up for American consumers, U.S. regulatory agencies such as the Environmental Protection Agency (EPA) and Food and Drug Administration (FDA) have largely turned a blind eye to concerns about glyphosate safety. The environmental website EcoWatch reported in 2016 that although the FDA routinely tests foods for pesticide residues, it had never tested for glyphosate residues until that year; EPA critics believe that the agency “has been unduly influenced by the agrichemical industry.” EcoWatch also observed that U.S. regulators allow a much higher “acceptable daily intake” of glyphosate than is permitted in other countries.

In July, 2019, Children’s Health Defense filed a lawsuit against Beech-Nut Nutrition Company, asserting that the company’s labeling and marketing practices “deceive parents who seek to be mindful of what is contained in the baby foods they provide to their infants.” Independent laboratory testing identified multiple synthetic pesticides, including glyphosate, in Beech-Nut’s “Naturals” line of baby food. Children’s Health Defense and Chairman and Chief Legal Counsel Robert F. Kennedy, Jr. take the health of our most precious resource—our children—very seriously and are at the forefront of legal efforts to challenge fraud and free children from exposure to toxic chemicals.

The rising toll of colorectal cancer deaths in young people who are in the prime of life points to the urgent need to reset regulatory priorities and put people before profits. Glyphosate’s deleterious effects on the gut microbiome—just one of many problems associated with the herbicide—are one more nail in the coffin for a toxic product that is well past its use-by date.

Sign up for free news and updates from Robert F. Kennedy, Jr. and the Children’s Health Defense. CHD is planning many strategies, including legal, in an effort to defend the health of our children and obtain justice for those already injured. Your support is essential to CHD’s successful mission.

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Awareness

Johnson & Johnson Found To Have Knowingly Allowed Asbestos In Their Baby Powder

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In Brief

  • The Facts:

    Johnson and Johnson have recently lost lawsuits for negligence in knowingly allowing carcinogenic substances in their talc-based hygiene products.

  • Reflect On:

    Are we starting to turn the page on an era where human health and safety are not the prime considerations in the manufacturing of consumer products?

We are starting to awaken to the fact that it seems to be the rule, and not the exception, that large Western corporations put profits above human health considerations. The only time they seem to give any regard to human health concerns is when their forecasts of potential lawsuits down the road would likely exceed the cost measures needed to ensure the safety of their product.

Johnson & Johnson is just one of a long line of corporate perpetrators who believed that covering up and lying about known health concerns would make better business sense than taking the time and resources to actually address those health concerns within their products.

Contaminated Baby Powder: The Height Of Indignity

One would think, regardless of an understanding that the bottom line is a priority for most private companies, that the health and safety of a nursing mother and her newborn child would be sacrosanct for any industry. The reality is that this is simply not the case, even though J&J could have mitigated this problem from the start.

Companies that mine talc are required to take extra steps to ensure the absence of asbestos in their talc. Instead, J&J allegedly went to great lengths to fake it.

Not only did the company know about the asbestos contamination, evidence suggests, but J&J also failed to warn its customers about the link between Baby Powder and cancer or replace its talc with a safer alternative. As a result, J&J guaranteed its customers’ exposure to asbestos.

And regardless of their size or numbers, asbestos fibers are lethal at any capacity. As the World Health Organization (WHO) has stressed repeatedly, there is no safe level of exposure. (source)

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The Testimony of Scientist James Webber

Baby Powder’s contamination with asbestos (a mineral that naturally occurs near talc) has long been the subject of lawsuits. But only in recent years has evidence begun to unravel J&J’s defense – that the company had no idea – and threatened its success in lawsuits to come.

In March, a California jury awarded $29 million to Terry Leavitt, a woman who said that asbestos in Johnson & Johnson’s talcum-powder-based products caused her terminal mesothelioma. Environmental scientist James Webber testified in her high-profile California trial and made these observations:

During several hours on the stand, Webber explained how he ran tests that showed “clear” evidence of asbestos contamination in the mines from which J&J sourced talc.

“The testing I have seen [shows] that it was present at least as early as 1971 and up through the late 1990s,” said Webber, who ran an asbestos laboratory in New York state.

Despite denying it publicly, J&J had observed this contamination in internal memos. Its notes dismissed the amount of asbestos in its talc as “but a trace,” Webber alleged. But that was just an optimistic interpretation of superficial testing, he said: the tests used methods too weak to detect microscopic asbestos fibers. Webber insisted the actual tests results revealed there could be millions of asbestos fibers per gram of talc.

And J&J’s inaccurate reports were allegedly only the tip of the iceberg. In some instances, Webber said, photos attached to J&J’s reports revealed that “they had been seeing it and not reporting it.”  (source)

And It’s Getting Worse

The $29 million verdict, in California Superior Court in Oakland, was the latest defeat for the healthcare conglomerate facing more than 13,000 talc-related lawsuits nationwide. And things may be getting even worse for J&J, according to ZeroHedge:

Johnson & Johnson shares are down over 5% after Bloomberg reports that, according to people with knowledge of the matter, the U.S. Justice Department is pursuing a criminal investigation into whether Johnson & Johnson lied to the public about the possible cancer risks of its talcum powder…

Now, a grand jury in Washington is examining documents related to what company officials knew about any carcinogens in their products, the people said.

The Takeaway

It seems as though corporations have long been willing to take the calculated risk of short-cuts and denials instead of ensuring that their products are safe for public use. My suspicion is that a part of our collective awakening process will be issuing in a new business paradigm in which human health and safety become paramount.

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Awareness

Prescription Infant Formulas Found To Be Contaminated With Aluminum

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In Brief

  • The Facts:

    Multiple brands of prescription infant formula were found to contain high levels of aluminum.

  • Reflect On:

    Should we be questioning the quality of products that come from pharmaceutical production? Do we veer away from natural methods of raising children more than we should? At what cost?

You may not think aluminum is a big deal, but it is. For anybody who has looked into aluminum toxicology, it’s quite clear and apparent that it has no place inside of any living biological organism. Putting it simply, it wreaks havoc on our biology. High amounts of aluminum have been found in the brains of people with Alzheimer’s disease, with experts in the field believing that aluminum brain accumulation may be one of the main causes of Alzheimer’s disease.

It’s also been discovered within the brains of MS patients, and some of the highest aluminum content ever recorded in brain tissue has also been discovered in people with autism. Aluminum is associated with several diseases. But an adult body can do a great job of flushing out aluminum.

Despite the fact that aluminum has no place within earth’s biota, it’s still present in many of our medications, our food, and even in the water that we drink due to contamination since the industrial revolution. Aluminum inside the body is a new phenomenon and still understudied. Again, there is a threshold, and aluminum that is injected via vaccines doesn’t exit the body–there is strong evidence that it remains inside the body and ends up in distant organs and eventually inside of the brain. If you want to access more studies on that topic, you can read this article I published that provides them and goes into more detail. You can also watch this interview with Christopher Exley, where he also points to that fact.

A new study published in the International Journal of Environmental Research and Public Health has shown that multiple popular infant prescriptions are contaminated with aluminum. You may be asking how much aluminum, but the authors make it a point to stress that there are no safe amounts of aluminum levels that can be inside of a human body, let alone a newborn baby. That being said, the amounts found are listed within the abstract of the study:

Historical and recent data demonstrate that off-the-shelf infant formulas are heavily contaminated with aluminium. The origin of this contamination remains to be elucidated though may be imported via ingredients, packaging and processing. Specialised infant formulas exist to address health issues, such as low birth weight, allergy or intolerance and medical conditions, such as renal insufficiency. The aluminium content of these prescription infant formulas is measured here for the first time. We obtained 24 prescription infant formulas through a paediatric clinic and measured their total aluminium content by transversely heated graphite furnace atomic absorption spectrometry following microwave assisted acid/peroxide digestion. The aluminium content of ready-to-drink formulas ranged from 49.9 (33.7) to 1956.3 (111.0) μg/L. The most heavily contaminated products were those designed as nutritional supplements for infants struggling to gain weight. The aluminium content of powdered formulas ranged from 0.27 (0.04) to 3.27 (0.19) μg/g. The most heavily contaminated products tended to be those addressing allergies and intolerance. Prescription infant formulas are contaminated with aluminium.

Another very important point made right off the bat by the authors:

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Human exposure to aluminium is a serious health concern. Aluminium exposure in infants is understandably a burgeoning issue. While infant exposure to aluminium continues to be documented, its consequences, immediate and in the future, have received only scant attention and research is required to understand the biological availability of aluminium through formula feeding. For example, how much aluminium is absorbed across the neonate gut and its subsequent fate, including excretion.

There is already too much aluminium in infant formulas and herein we have measured its content in a large number of prescription formulas, products which are fed to vulnerable infants in their first months of life. Many of these products are heavily contaminated with aluminium.

As for the specific infant formulas, you can refer to the study. The researchers obtained 24 prescription infant formulas via the Paediatric Clinic of Russells Hall Hospital in Dudley, United Kingdom. The ready-to-drink and powdered products were new, ready-to-be used and unopened samples. These formulas are for babies with some sort of growth restriction, like for preterm infants or infants who have poor weight gain. There were also powdered formulas for allergies and intolerances and powdered formulas with additional amino acids.

The authors contacted each manufacturer and expressed that they denied knowing that there was any aluminum in their products, which means it’s still a mystery as to their source. The authors hypothesize on a number of ways that aluminum could be entering into the formulas.

In their conclusion, the authors emphasize that:

Where possible, breast milk feeding should be prioritised, as the aluminium content of breast milk is invariably an order of magnitude lower than in formula feeds. Where infant formulas are the only source of nutrition for many infants in their first weeks and months of life, aluminium ingested in formula feeds will be the major contributor to their body burden of aluminium. The last thing that vulnerable infants fed specialised formulas for their specific nutritional/medicinal need is additional aluminium in their diet.

Detoxing

There is a lot of information out there on how a person can detox from aluminum and other heavy metals. There are multiple studies, and based on what I’ve looked into, water with high amounts of Silica are effective in draining aluminum out of your body and brain. Herbs like cilantro and substances like chlorella and spirulina are also great for removing some metals. The information is out there, so be sure to do your research.

The Takeaway

It’s concerning to think about what these corporations are doing. Again, aluminum should hold no place in our society, it should’ve remained well below our surface as part of the Earth’s crust for a reason. It wasn’t until humans began digging it out and using it for a number of things, irresponsibly I might add, that we started to see the health implications which still go largely ignored by the medical community.

In fact, heavy metal accumulation and detoxification of aluminum haven’t been addressed at all, which is odd given the fact that heavy metal accumulation is linked to a variety of diseases.

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