- The Facts:
This article was originally written and published at Greenmedinfo.com, written by the GreenMedInfo Research Group and posted here with permission.
- Reflect On:
Juice fasts, formerly relegated to groups on the fringes of society, are now embraced by mainstream culture. Once only a ritual rite of passage for those embedded in natural medicine circles, juice fasts have now become ubiquitous, marketed by health gurus, infomercials, and integrative medical doctors alike.
Juice fasts, formerly relegated to groups on the fringes of society, are now embraced by mainstream culture. Once only a ritual rite of passage for those embedded in natural medicine circles, juice fasts have now become ubiquitous, marketed by health gurus, infomercials, and integrative medical doctors alike.
Despite an abundance of anecdotal evidence and the testimonies of countless juicing enthusiasts, well-designed controlled studies on the subject have remained scant (1).
Gut Microbiota: The Gateway to Good Health
The gut microbiota, or the one hundred trillion commensal bacteria that inhabit our gastrointestinal tracts, may be the vehicle through which juice fasts elicit their beneficial effects. Not only is a disturbed microbiota implicated in the pathogenesis of obesity and metabolic disorders, but weight reduction has been reported to engender improvements in levels of bacterial species that contribute to inflammatory processes (2). In particular, “Obesity is associated with lower bacterial diversity, phylum and genus-level changes, and altered representation of bacterial genes and metabolic pathways involved in nutrient harvest” (2, p. 394).
One study performed by Remely and colleagues (2015) examined the effects of a traditional diet in an Austrian monastery, comprised of small amounts of soup, cereal, fruit and vegetable juices, and herbal teas (2). This intervention, implemented in obese subjects, significantly increased microbial diversity as well as numbers of Bifidobacteria, Akkermansia, and Faecalibacterium prausnitzii. Mucin-degrading Akkermansia, which have high mucosal adherence and are correlated with a healthy gut microbial community, are depleted in inflammatory disorders such as Crohn’s disease and ulcerative colitis (3, 4).
The researchers also reported that populations of Enterobacteria and Lactobacilli associated with inflammation declined after the intervention (2). The authors concluded, “Our results show that caloric restriction affects the gut microbiota by proliferating mucin-degrading microbial subpopulations,” demonstrating that juice fasts may operate through this mechanism (p. 394). Other models of caloric restriction have similarly yielded decreases in Streptococcacae, which incite mild inflammation, and increases in Lactobacillus species, which competitively inhibit pathogens and produce declines in inflammatory cytokine levels (5).
Polyphenol-Induced Microbiome Changes Favorably Influence Health
Fruits and vegetables represent the richest reservoir of phenolic compounds, which resist absorption in the small intestine and instead are metabolized by the colonic bacteria into compounds which modulate populations of gut flora. Researchers speculate that the microbiota may be a previously under-recognized avenue through which polyphenols promote health, improve metabolic parameters, and mitigate inflammation (6).
For instance, when rats are given quercetin, a flavonoid found in plant foods such as apples and onions, microbial dysbiosis induced by a high-fat high-sucrose diet is inhibited (7, 8). The rats in this experiment likewise exhibited suppressed growth of bacterial species correlated with diet-induced obesity, such as Erysipelotrichaceae, Eubacterium cylindroides, and Bacillus, alongside an attenuated ratio of Firmicutes to Bacteroidetes (7). Further, when administered in concert, quercetin and trans-resveratrol prevented weight gain in a rodent model, whereas individually, they each improved insulin resistance (7). In isolation, supplementation with trans-resveratrol also modified expression of tight-junction proteins and inflammatory gene profiles, influencing intestinal permeability in ways likely mediated by the microbiota (7).
In another study, mice receiving Concord grape polyphenols with a high-fat diet exhibited improved profiles of glucose tolerance, adiposity, and weight gain, and had enhanced expression of fasting-induced adipocyte factor, which restricts triglyceride storage (6). The mice receiving grape polyphenols similarly displayed reduced levels of inflammatory markers, such as the inflammatory cytokines tumor necrosis factor (TNF)-α and interleukin (IL)-6, the endotoxin released from gram-negative bacteria called lipopolysaccharide (LPS), and inducible nitric oxide synthase (iNOS) (6). In addition, grape polyphenols improved intestinal barrier function by up-regulating the genes for occludin and proglucagon, the former of which is a tight junction architectural protein, and the latter of which is a precursor to proteins that maintain mucosal barrier integrity and promote insulin production (6).
Importantly, grape polyphenols induced dramatic alterations in the community of commensal microbes. This botanical reduced the ratio of Firmicutes and Bacteroidetes, which is significant since an increased ratio of Firmicutes to Bacteroidetes, which is induced by a high-fat, high sugar diet, has been shown to increase host adiposity when transplanted into germ-free mice (9, 10, 11). The grape polyphenols also significantly augmented populations of Akkermansia muciniphila, an obligate anaerobic species which blooms after gastric bypass surgery and promotes weight loss when transplanted into germ-free recipients (11, 12). In addition, cross-sectional studies have underscored that higher levels of A. municiphila appear in lean individuals relative to obese individuals (13). Because A. muciniphila is vulnerable to reactive oxygen species, the free radical scavenging capacity of grape polyphenols can create a more hospitable environment for this species and other obligate anaerobes that benefit health (6).
Likewise, cranberry polyphenols induced similar anti-diabetic effects in mice fed a high-fat, high sucrose (HFHS) diet (14). Administration of cranberry extract improved insulin sensitivity and glucose handling, lowering intestinal, plasma, and hepatic triglyceride levels, and reduced intestinal and hepatic inflammation and oxidative stress (14). Cranberry extract similarly attenuated circulating levels of LPS, effectively preventing the HFHS-induced metabolic endotoxemia that contributes to the pathophysiology of cardiovascular disease (14). Moreover, like grape polyphenols, treatment with cranberry extract led to dramatic elevations in A. muciniphila, which confers protection against metabolic syndrome features (14).
Other studies have elucidated that dealcoholized red wine polyphenols and cocoa-derived flavanols elicit similar effects on the gut microbiota (15). Collectively, polyphenols “modulate the human gut microbiota by decreasing the abundance of Firmicutes and increasing Bifidobacteria, Lactobacillus and Verrucomicrobia, which is also a key difference in the gut microbiota found in obese and lean individuals” (15, p.1).
Based on the aforementioned findings, researchers suggest that myriad distinct polyphenols and bioactive compounds may exert similar effects, both directly and indirectly, on the gut microbiome. They propose that diverse classes of dietary antioxidants may engender health benefits by conferring a survival advantage for certain commensal species (6). According to Roopchand and colleagues (2015), “We propose that this altered gut microbiota is, in part, responsible for the altered intestinal gene expression, epithelial integrity, and inflammatory markers, which then leads to decreased fat deposition and glucose absorption, along with increased insulin secretion” (6, p. 2857).
Changes in Gut Microbiota After a Juice Fast
Based on the premise that changes in microbial composition influence health, researchers designed a study to examine whether a three-day juice fast, followed by reversion to a customary diet for two weeks, would favorably influence the microbiota composition of twenty healthy subjects with low fruit and vegetable consumption (15). A root juice mix was blended from beet, apple, ginger, and lemon, whereas a citrus juice mix consisted of apple, pineapple, mint, and lemon, and the green juice mixes contained romaine lettuce, apple, cucumber, celery, lemon, and small fractions of kale, parsley, and spinach (15). Also included was a mix consisting of filtered water, lemon, cayenne, almond, vanilla bean, dates, and sea salt (15).
Whereas proportions of certain intestinal bacteria, such as Fusobacteria, Actinobacteria, Verrucomicrobia, and Proteobacteria remained consistent, a significant decrease in Firmicutes and increases in both Cyanobacteria and Bacteroidetes were observed in subjects undergoing the juice fast compared to baseline (15). Firmicutes and Bacteroidetes represent the two most abundant bacterial phyla in human populations, representing 40-60% and 20-40% of the microbiota, respectively (16).
Increased Firmicutes in relation to Bacteroidetes has been correlated with obesity and body mass index (BMI) in some human studies (17). According to researchers, “Comparisons of the distal gut microbiota of genetically obese mice and their lean littermates, as well as those of obese and lean human volunteers have revealed that obesity is associated with changes in the relative abundance of the two dominant bacterial divisions, the Bacteroidetes and the Firmicutes” (18, p.1027). The microbiome characteristic of the obese phenotype, in turn, has been correlated with increased harvesting of energy from the diet, and produces obesity when germ-free mice are colonized with the obese microbiota (18).
This trend, which has been supported by some studies and refuted by others, was reinforced by the present juice fast, where a significant positive correlation between weight at day four and Firmicutes proportion, and a significant negative correlation between weight at day four and Bacteroidetes proportion was observed (13, 15, 18). These changes in microbiota may mitigate or perpetuate metabolic syndrome features by regulating gut barrier function, as animal models have confirmed that a compromised gut barrier enables translocation of bacteria and antigens, which evokes inflammation from the gut-associated sub-mucosal lymphoid system (13).
In addition, Bacteroides species such as B. ovatus, B. thetaiotaomicron, and B. uniformis can ferment a wide array of indigestible complex polysaccharides, such as fruit- and vegetable-based xylan and pectin (19). These carbohydrates serve as fermentable substrates or prebiotics, which are metabolized into health promoting, gut sealing, cardioprotective short chain fatty acids. According to Flint and colleagues (2012), “Certain dominant species, notably among the Bacteroidetes, are known to possess very large numbers of genes that encode carbohydrate active enzymes and can switch readily between different energy sources in the gut depending on availability” (19, p. 289). The enrichment in Bacteroides species after the juice fast reinforces the prebiotic effects of juice, since similar increases in Bacteroides species such as B. acidifaciens, B. ovatus, and B. xylanisolvens were witnessed in studies of subjects with metabolic syndrome who included resistant starch in their diets (20).
In one particular study, flourishing of Bacteroides species was accompanied by significant decreases in fasting glucose, glycosylated hemoglobin, cholesterol levels, body fat, waist circumference, and pro-inflammatory markers, which speaks to the metabolic benefits incurred with strategies that augment Bacteroides populations (20). In addition, another rodent study showed that B. thetaiotaomicron combined with probiotics decreased mean body weight and reduced levels of postprandial triglycerides in rats fed a high fat diet, further illustrating the benefit of these specific microbes (21).
After the juice fast, populations of Bacteroides, Odoribacteri, Paraprevotella, Barnesiella, and Halospirulina were all enhanced at day four compared to baseline, whereas Eisenbergiella, Dialister, Ruminiclostridium, Subdoligranulum, and Streptococcus were all suppressed at day four compared to baseline, illuminating the immediate and dramatic effect that fruit and vegetable polyphenols can elicit on the microbiota (15). These other genera, however, besides Streptococcus, returned to baseline levels at day seventeen, indicating the need for regular polyphenol consumption to maintain favorable microbiome changes (15).
Effect of a Juice Fast on Inflammation
Although plasma antioxidant capacity remained unchanged after the juice fast, lipid peroxidation, as measured by urine malondialdehyde (MDA), significantly decreased by 40% at day four compared to baseline (15). The researchers attribute this to either the low-fat nature of the juice fast, such that fewer lipids are available for oxidative degradation, or the antioxidant protection conferred by juice polyphenols for lipids during digestion (15).
This latter hypothesis is supported by research demonstrating that polyphenol-rich juices containing cyanidin glycosides and epigallocatechin gallate (EGCG) supplemented for two weeks led to decreases in plasma MDA (22). In addition, red wine polyphenols have been shown to completely prevent the rise in plasma MDA that occurs due to oxidized fats (23). Similarly, rosmarinic acid, a polyphenol in oregano, significantly reduces MDA concentration in plasma and urine after burger consumption (24). Thus, the high polyphenol content in juices may protect against the carcinogenic and atherosclerotic effects of lipid peroxidation.
In addition, after the juice fast, day four nitric oxide (NO) concentrations were increased by five-fold and three-fold, in urine and plasma, respectively, compared to baseline, indicating the vasodilatory effect of fruit and vegetable nitrate content (15). Optimizing NO levels may prevent cardiovascular disease, since disturbed activity of endothelial nitric oxide synthase (eNOS) is implicated in the pathophysiology of endothelial dysfunction, impaired arterial compliance, and hypertension. This is consistent with prior work which elucidated that nitrate-rich beet juice improves vascular function in hypercholesterolemic patients, as illustrated by increases in flow-mediated dilatation (FMD) and aortic pulse wave velocity and by decreases in platelet-monocyte aggregates compared to placebo (25). These changes may also be mediated by the microbiome, and nitrate-reducing bacteria specifically, since in one study, nitrate treatment modified the proportions of 78 bacterial taxa in the salivary microbiome compared to placebo (25).
Lastly, during the juice intervention, significant decreases in body weight and body mass index (BMI) occurred which persisted after the two-week follow-up period (15). Well-being scores remained consistent with baseline at day three, but there was a significant increase in well-being at the conclusion of the study (15). However, both NO and MDA concentrations returned to initial baseline values at day seventeen, suggesting that continued consumption of polyphenols is required to maintain anti-inflammatory benefits (15).
Although the fiber is largely removed from juice, this study highlights that juicing still elicits a prebiotic effect due to its polyphenol content, and that it can therefore favorably modify the microbiome by selectively stimulating the growth of beneficial commensal bacteria. Thus, juicing, with an emphasis on lower glycemic vegetables, may be both a prudent adjunctive strategy for people with gastrointestinal distress who cannot tolerate large quantities of fiber, and for individuals with metabolic derangements.
1. Horne, B.D., Muhlestein, J.B., & Anderson, J.L. (2015). Health effects of intermittent fasting: hormesis or harm? A systematic review. The American Journal of Clinical Nutrition, 102, 464–470, doi: 10.3945/ajcn.115.109553 (2015).
2. Remely, M. et al. (2015). Increased gut microbiota diversity and abundance of Faecalibacterium prausnitzii and Akkermansia after fasting: a pilot study. Wiener Klinische Wochenschrift, 127, 394–398, doi: 10.1007/s00508-015-0755-1
3. Png, C.W. et al. (2010). Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria. American Journal of Gastroenterology, 105(11), 2420-2428.
4. Belzer, C., & de Vos, W.M. (2012). Microbes inside-from diversity to function: the case of Akkermansia. International Society of Microbial Ecology Journal, 8(8), 1449-1458.
5. Zhang, C. et al. (2013). Structural modulation of gut microbiota in life-long calorie-restricted mice. Natural Communications, 4, 2163.
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7. Etxeberria, U. et al. (2015). Reshaping faecal gut microbiota composition by the intake of trans-resveratrol and quercetin in high-fat sucrose diet-fed rats. Journal of Nutritional Biochemistry, 26(6), 651-660. doi: 10.1016/j.jnutbio.2015.01.002. 41-46.
8. Lee, J., & Mitchell, A.E. (2012). Pharmacokinetics of quercetin absorption from apples and onions in healthy humans. Journal of Agricultural and Food Chemistry, 60, 3874-3881.
9. Carmody, R.N. et al. (2015). Diet dominates host genotype in shaping the murine gut micorbiota. Cell Host Microbe, 2015, 72-84.
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11. Liou, A.P. et al. (2013). Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity. Science of Translational Medicine, 5, 178ra141.
12. Zhang, H. et al. (2009). Human gut microbiota in obesity and after gastric bypass. Proceedings of the National Academy of Sciences (USA), 106, 2365-2370.
13. Stenman, L. K., Burcelin, R. & Lahtinen, S. Establishing a causal link between gut microbes, body weight gain and glucose metabolism in humans – towards treatment with probiotics. Beneficial microbes 1–12, doi:10.3920/BM2015.0069 (2015).
14. Anhê, F.F. et al. (2015). A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice. Gut, 64, 872-883.
15. Henning, S.M., et al. (2017). Health benefit of vegetable/fruit juice-based diet: Role of microbiome. Scientific Reports, 7. doi:10.1038/s41598-017-02200-6
16. Million, M. et al. (2013). Gut bacterial microbiota and obesity. Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 19, 305–313, doi: 10.1111/1469-0691.12172
17. Koliada, A. et al. (2017). Association between body mass index and Firmicutes/Bacteroidetes ratio in an adult Ukrainian population. BioMed Central Microbiology. https://doi.org/10.1186/s12866-017-1027-1
18. Turnbaugh, P.J. et al. (2006). An obesity-associated gut microbiome with increased capacity for energy harvest. Nature, 444, 1027–1031, doi:10.1038/nature05414
19. Flint, H.J. et al. (2012). Microbial degradation of complex carbohydrates in the gut. Gut Microbes, 3(4), 289-306.
20. Upadhyaya, B. et al. (2016). Impact of dietary resistant starch type 4 on human gut microbiota and immunometabolic functions. Scientific Reports, 6, 28797, doi: 10.1038/srep28797 (2016).
21. Olli, K. et al. (2016). Independent and Combined Effects of Lactitol, Polydextrose, and Bacteroides thetaiotaomicron on Postprandial Metabolism and Body Weight in Rats Fed a High-Fat Diet. Frontiers in Nutrition, 3, 15, doi: 10.3389/fnut.2016.00015
22. Bub, A. et al. (2003). Fruit juice consumption modulates antioxidative status, immune status and DNA damage. Journal of Nutritional Biochemistry, 14(2), 90-98.
23. Gorelik, S. et al. (2007). A novel function of red wine polyphenols in humans: prevention of absorption of cytotoxic lipid peroxidation products. The Official Journal of the Federation of American Societies for Experimental Biology, 22(1).
24. Li, Z. et al. (2010). Antioxidant-rich spice added to hamburger meat during cooking results in reduced meat, plasma, and urine malondialdehyde concentrations. The American Journal of Clinical Nutrition, 91, 1180–1184. doi:10.3945/ajcn.2009.28526
25. Velmurugan, S. et al. (2016). Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study. The American Journal of Clinical Nutrition, 103, 25–38, doi: 10.3945/ajcn.115.116244
Studies Show We Can Heal With Sound, Frequency & Vibration
- The Facts:
Multiple studies and examples have shown how sound, frequency and vibration can literally alter physical material matter. Research has also shown that sound, frequencies and vibration can be used as a significant healing method for various ailments.
- Reflect On:
How plausible would it be for these interventions to become a regular part of therapy, just as much as pharmaceutical drugs are now?
Cymatics is a very interesting topic. It illustrates how sound frequencies move through a particular medium such as water, air, or sand and as a result directly alter physical matter. There are a number of pictures all over the internet as well as youtube videos that demonstrate how matter (particles) adjust to different sounds and different frequencies of sound.
When it comes to ancient knowledge, sound, frequency and vibration have always been perceived as powerful forces that can influence and alter life all the way down to the cellular level. Sound healing methods are often used by Shamans, who employ drums and singing to access trance states. Research has even demonstrated that drumming and singing can can be used to slow fatal brain disease, and it can generate a sense of oneness with the universe . Sound therapy is getting more popular, and it can have many medical applications, especially within the psychological and mental health realms.
Sound, frequency and vibration are used all throughout the animal kingdom, and there are many examples. If we look at the wasp, they use antennal drumming to alter the caste development or phenotype of their larvae. Conventional thinking has held for quite some time that differential nutrition alone can explain why one larvae develops into a non-reproductive worker and one into a reproductive female (gyne). However, this is not the case, according to a 2011 study:
“But nutrition level alone cannot explain how the first few females to be produced in a colony develop rapidly yet have small body sizes and worker phenotypes. Here, we provide evidence that a mechanical signal biases caste toward a worker phenotype. In Polistes fuscatus, the signal takes the form of antennal drumming (AD), wherein a female trills her antennae synchronously on the rims of nest cells while feeding prey-liquid to larvae. The frequency of AD occurrence is high early in the colony cycle, when larvae destined to become workers are being reared, and low late in the cycle, when gynes are being reared. Subjecting gyne-destined brood to simulated AD-frequency vibrations caused them to emerge as adults with reduced fat stores, a worker trait. This suggests that AD influences the larval developmental trajectory by inhibiting a physiological element that is necessary to trigger diapause, a gyne trait.”
This finding indicates that the acoustic signals produced through drumming within certain species carry biologically meaningful information (literally: ‘to put form into’) that operate epigenetically (i.e. working outside or above the genome to affect gene expression).
Pretty fascinating, isn’t it? Like many other ancient lines of thought, this has been backed by modern day scientific research.
Another example comes from cancer research. In his Tedx talk, “Shattering Cancer with Resonant Frequencies,” Associate Professor and Director of Music at Skidmore College, Anthony Holland, tells the audience that he has a dream. That dream is to see a future where children no longer have to suffer from the effects of toxic cancer drugs or radiation treatment, and today he and his team believe they have found the answer, and that answer is sound. Holland and his team wondered if they could affect a cell by sending a specific electric signal, much like we do with LCD technology. After searching the patent database for a device that could accomplish this, they came across a therapeutic device invented by New Mexico physician Dr. James Bare. The device uses a plasma antenna that pulses on and off, which, as Holland explains, is important because a constant pulse of electricity would produce too much heat and therefore destroy the cell. For the next 15 months, Holland and his team searched for the exact frequency that would directly shatter a living microorganism. The magic number finally came in the form of two inputs, one high frequency and one low. The high frequency had to be exactly eleven times higher than the low, which in music is known as the 11th harmonic. At the 11th harmonic, micro organisms begin to shatter like crystal glass.
After consistently practicing until they became efficient at the procedure, Holland began working with a team of cancer researchers in an attempt to destroy targeted cancer cells. First they looked at pancreatic cancer cells, eventually discovering these cells were specifically vulnerable between 100,000 – 300,000 Hz.
Next they moved onto leukemia cells, and they were able to shatter the leukemia cells before they could divide. But, as Holland explains in his talk, he needed bigger stats in order to make the treatment a viable option for cancer patients.
In repeated and controlled experiments, the frequencies, known as oscillating pulsed electric field (OPEF) technology, killed an average of 25% to 40% of leukemia cells, going as high as 60% in some cases. Furthermore, the intervention even slowed cancer cell growth rates up to 65%.
You can read more about the story, find sources, and watch that TEDx talk here.
Another example occurred in 1981, when biologist Helene Grimal partnered with composer Fabien Maman to study the relationship of sound waves to living cells. For 18 months, the pair worked with the effects of 30-40 decibel sounds on human cells. With a camera mounted on a microscope, the researchers observed uterine cancer cells exposed to different acoustic instruments (guitar, gong, xylophone) as well as the human voice for 20-minute sessions.
They discovered that, when exposed to sound, cancer cells lost structural integrity until they exploded at the 14-minute mark. Far more dramatic was the sound of a human voice — the cells were destroyed at the nine-minute mark.
After this, they decided to work with two women with breast cancer. For one month, both of the women gave three-and-a-half-hours a day to “toning” or singing the scale. Apparently, the woman’s tumor became undetectable, and the other woman underwent surgery. Her surgeon reported that her tumor had shrunk dramatically and “dried up.” It was removed and the woman had a complete recovery and remission.
These are only a few out of multiple examples that are floating around out there.
Let’s not forget about when Royal Rife first identified the human cancer virus using the world’s most powerful microscope. After identifying and isolating the virus, he decided to culture it on salted pork. At the time this was a very good method for culturing a virus. He then took the culture and injected it into 400 rats, which, as you might expect, created cancer in all 400 rats very quickly. The next step for Rife was where things took an interesting turn. He later found a frequency of electromagnetic energy that would cause the cancer virus to diminish completely when entered into the energy field. You can read more about that story here.
A 2014 study published in the Journal of Huntington’s Disease found that two months of drumming intervention in Huntington’s patients (considered an irreversible, lethal neurodegenerative disease) resulted in “improvements in executive function and changes in white matter microstructure, notably in the genu of the corpus callosum that connects prefrontal cortices of both hemispheres.” The study authors concluded that the pilot study provided novel preliminary evidence that drumming (or related targeted behavioral stimulation) may result in “cognitive enhancement and improvements in callosal white matter microstructure.”
A 2011 Finnish study observed that stroke patients who were given access to music as cognitive therapy had improved recovery. Other research has shown that patients suffering from loss of speech due to brain injury or stroke regain it more quickly by learning to sing before trying to speak. The phenomenon of music facilitating healing in the brain after a stroke is called the “Kenny Rogers Effect.”
A 2012 study published in Evolutionary Psychology found that active performance of music (singing, dancing and drumming) triggered endorphin release (measured by post-activity increases in pain tolerance), whereas merely listening to music did not. The researchers hypothesized that this may contribute to community bonding in activities involving dance and music-making.
According to a study published by the National Institute of Health, “Music effectively reduces anxiety for medical and surgical patients and often reduces surgical and chronic pain. [Also,] Providing music to caregivers may be a strategy to improve empathy, compassion, and care.” In other words, music is not only good for patients, it’s good for those who care for them as well.
Below is an interesting interview with Dr. Bruce Lipton. You can view his curriculum vitae here.
The information presented in this article isn’t even the tip of the iceberg when it comes the the medical applications of sound, frequency and vibration, which are all obviously correlated. One thing is clear, however, which is that there are many more methods out there, like the ones discussed in this article, that should be taken more seriously and given more attention from the medical establishment. It seems all mainstream medicine is concerned about is making money and developing medications that don’t seem to be representative of our fullest potential to heal. “Alternative” therapies shouldn’t be labelled as alternative, they should be incorporated into the norm.
Mental Health Problems—The Sad “New Normal” on College Campuses
College campuses are witnessing record levels of student mental health problems, ranging from depression and anxiety disorders to self-injurious behaviors and worse. A clinician writing a few years ago in Psychology Today proclaimed it neither “exaggeration” nor “alarmist” to acknowledge that young Americans are experiencing “greater levels of stress and psychopathology than any time in the nation’s history”—with ramifications that are “difficult to overstate.”
The problems on college campuses are manifestations of challenges that begin sapping American children’s health at younger ages. For example, many students enter college with a crushing burden of chronic illness or a teen-onset mental health diagnosis that has made them dependent on psychotropic or other medications. The childhood prevalence of different forms of cognitive impairment has also increased and is associated with subsequent mental health difficulties. In addition, a majority of American students are now unprepared academically for their college careers, as evidenced by historically low levels of achievement on standardized tests. Once in college, large proportions of students—increasingly characterized as emotionally fragile—blame mental health challenges for significantly interfering with their ability to perform. The outcomes of these trends—including rising suicide rates among students and declining college completion rates—bode poorly for young people’s and our nation’s future.
… more than three in five (63%) respondents reported experiencing overwhelming anxiety in the past year, while two in five (42%) reported feeling so depressed that it was difficult to function.
Crippling anxiety and depression
A 2018 survey at 140 educational institutions asked almost 90,000 college students about their health over the past 12 months. The survey found that more than three in five (63%) respondents reported experiencing “overwhelming anxiety” in the past year, while two in five (42%) reported feeling “so depressed that it was difficult to function.” Students also reported that anxiety (27%), sleep difficulties (22%) and depression (19%) had adversely affected their academic performance.
In the same survey, 12% of college students reported having “seriously considered suicide.” Another study, which looked at college students with depression, anxiety and attention-deficit/hyperactivity disorder (ADHD) who had been referred by college counseling centers for psychopharmacological evaluation, found that the same proportion—12%—had actually made at least one suicide attempt. Half of the students in the latter study had previously received a prescription for medication, most often antidepressants.
Colleges are feeling the squeeze, with demand growing nationally for campus mental health services. A study by Penn State’s Center for Collegiate Mental Health reported an average 30% to 40% increase in students’ use of counseling centers between 2009 and 2015 at a time when enrollment grew by just 5%. According to Penn State’s report, the “increase in demand is primarily characterized by a growing frequency of students with a lifetime prevalence of threat-to-self indicators.”
Most colleges expect new students to have had the full complement of CDC-recommended childhood vaccines and to top up before college matriculation with any vaccines or doses that they may have previously missed. In particular, universities are likely to emphasize tetanus-diphtheria-pertussis (Tdap) and measles-mumps-rubella (MMR) boosters; the human papillomavirus (HPV) vaccine; meningococcal vaccination; and annual flu shots.
… found particularly strong associations for three disorders common on college campuses—anorexia nervosa, obsessive-compulsive disorder and anxiety disorders—and observed a surge in diagnosed disorders after influenza vaccination (one of the vaccines that college students are most likely to get).
It is unlikely that clinics are issuing warnings to freshly vaccinated college students about potential adverse consequences to watch out for, yet two universities (Penn State and Yale) made news in 2017 when their researchers published a study showing a temporal relationship between newly diagnosed neuropsychiatric disorders and vaccines received in the previous three to twelve months. Although the researchers analyzed health records for 6- to 15-year-old children, not college students, they found particularly strong associations for three disorders common on college campuses—anorexia nervosa, obsessive-compulsive disorder and anxiety disorders—and observed a surge in diagnosed disorders after influenza vaccination (one of the vaccines that college students are most likely to get). They also detected significant temporal associations linking meningitis vaccination to both anorexia and chronic tic disorders.
To distance themselves from too strongly implicating vaccines, these researchers later proposed several less controversial mechanisms to explain their findings, including the presence of predisposing inflammatory or genetic factors. One of the researchers even suggested that the “trauma” of getting “stuck with needles” might be triggering the adverse neuropsychiatric outcomes.
This absurd sidestepping ignores considerable experimental evidence from both animals and humans linking the immune responses produced by vaccines (and vaccine adjuvants) to adverse mental health symptoms. In fact, some researchers vaccinate healthy animals or people on purpose just to study this phenomenon. For example:
- A study intentionally injected mice with the vaccine used against tuberculosis (BCG vaccine) to induce “depression-like behavior,” finding that the vaccine-induced depression was resistant to treatment with standard antidepressants.
- Another study in mice found that both the antigens and the aluminum adjuvant in the Gardasil HPV vaccine produced significantly more behavioral abnormalities, including depression, in the exposed mice compared to unexposed mice.
- University of California researchers followed healthy undergraduates for one week before and one week after influenza vaccination; in the absence of any physical symptoms, they detected increased post-vaccination inflammation that was associated with more mood disturbances—especially “depressed mood and cognitive symptoms.”
- Another study of influenza vaccination compared vaccine recipients who had preexisting depression and anxiety to “mentally healthy” recipients, finding that both groups had “decreased positive affect” following vaccination; however, the vaccine’s impact on mood was “more pronounced for those with anxiety or depression.”
- Neuroscientists at Oxford injected healthy young adults with typhoid vaccine to explore “the link between inflammation, sleep and depression,” finding that the vaccine “produced significant impairment in several measures of sleep continuity” in the vaccine group compared to placebo; the researchers noted in their conclusions that impaired sleep is both a “hallmark” and “predictor” of major depression.
- Another group of UK researchers who likewise injected healthy young adult males with the typhoid vaccine found that, within hours, the vaccine had produced measurable social-cognitive deficits.
Interestingly, a study conducted in 2014 found that vaccine-mental health effects may cut both ways. Researchers who assessed self-reported depression and anxiety (and other measures) in 11-year-olds before and up to six months after routine vaccination found that children who reported more initial depressive and anxious symptoms had a stronger vaccine response(defined by “elevated and persistently higher antibody responses”) and that this association remained even after controlling for confounders. Given that this type of overactive vaccine response can be a harbinger of autoimmunity, some researchers have urged more attention to these “bidirectional” effects.
… we are kidding ourselves if we ignore the possible contribution of a cumulative vaccine load that has children receiving dozens of doses by age 18 …
afe spaces or safe vaccines?
As “safe spaces” multiply on college campuses, and elite private institutions offer dumbed-down for-credit courses like “The Sociology of Miley Cyrus” or “Beginning Dungeons and Dragons,” it is time to take stock of the health challenges—both mental and physical—that are sabotaging college students’ chances of success. Researchers already have noted a disturbing mismatchbetween available cognitive abilities and the types of “non-routine analytical-cognitive” skills that our nation will increasingly need in the future. While variables such as student debt certainly factor into college students’ stress equation, we are kidding ourselves if we ignore the possible contribution of a cumulative vaccine load that has children receiving dozens of doses by age 18—and piles on even more when kids go off to college.
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Vaccine Rhetoric vs. Reality—Keeping Vaccination’s Unflattering Track Record Secret
Note: This is Part VI in a series of articles adapted from the second Children’s Health Defense eBook: Conflicts of Interest Undermine Children’s Health. The first eBook, The Sickest Generation: The Facts Behind the Children’s Health Crisis and Why It Needs to End, described how children’s health began to worsen dramatically in the late 1980s following fateful changes in the childhood vaccine schedule.]
A concerted and “heavy-handed” effort is under way to censor information that contradicts the oversimplified sound bites put forth by public health agencies and the media about vaccines. However, while brazen, in-your-face censorship—and attacks on health freedom—have ratcheted up to an unprecedented degree, officialdom’s wish to keep vaccination’s unflattering track record out of the public eye is nothing new.
There is a chasm between vaccine rhetoric and reality for most if not all vaccines, but four vaccines—varicella (chickenpox), rotavirus, human papillomavirus (HPV) and pertussis-containing vaccines—offer especially instructive before-and-after case studies. Analysis of the U.S. experience with these vaccines raises important questions. First, why did the Food and Drug Administration (FDA) race to approve—and why does the Centers for Disease Control and Prevention (CDC) heavily promote—vaccines such as varicella and rotavirus when there is little public health justification for them? Second, why are federal agencies ignoring the many serious risks that have surfaced in the vaccines’ wake—problems unheard of before the vaccines’ introduction?
With the rollout of mass varicella vaccination, shingles started cropping up to an unprecedented extent in both children and adults, eliminating boosting for adults and shifting downward the average age at which shingles occurs.
Varicella and rotavirus vaccines
The rationale for the varicella and rotavirus vaccines was dubious from the start. In the U.S. and other wealthy countries, varicella and rotavirus were nearly universal and mostly benign childhood infections; in those settings, the pre-vaccine impact of the two conditions was largely measured in terms of “healthcare costs, missed daycare, and loss of time from work for parents/guardians” rather than in terms of serious illness or mortality.
Childhood chickenpox infections served an important purpose for all, conferring lifelong immunity to infected children while boosting adult immunity to the related shingles (herpes zoster) virus. With the rollout of mass varicella vaccination, shingles started cropping up to an unprecedented extent in both children and adults, eliminating boosting for adults and shifting downward the average age at which shingles occurs. Vaccine waning also began increasing young adults’ risk for varicella outbreaks and complications later in life, presenting “perverse public health implications.” Meanwhile, the CDC and its local public health partners worked hard to conceal these unwanted chickenpox vaccine outcomes from the public.
Rotavirus vaccines have had a similarly checkered history. Soon after their introduction in the U.S., reports emerged of a substantially increased risk in infants of an otherwise rare bowel complication called intussusception. The FDA knew about the problem during the prelicensing regulatory review process but ignored it. Although the agency subsequently withdrew its approval for one of the problematic rotavirus vaccines, it was not until after an estimated 500,000 children received at least one million doses. The FDA never explained the “precise mechanism” by which the discontinued vaccine caused intussusception.
Two rotavirus vaccines that display the same intussusception risks are still on the U.S. market. Both are contaminated with foreign DNA from porcine viruses capable of causing severe immunodeficiency in pigs. Had the presence of these “adventitious agents” been discovered prior to vaccine licensure, the FDA probably would have been forced to shelve the vaccines, yet they remain on the vaccine schedule to this day.
The speed with which the FDA gave them [HPV vaccines Gardasil and Gardasil-9] the go-ahead—despite obvious red flags regarding their safety—illustrates the insincerity of the agency’s assertions that its vaccine approval process is committed to minimizing risks.
The HPV vaccines Gardasil and Gardasil-9 (manufactured by Merck) represent perhaps an even more compelling case study of risk-laden vaccines that should have attracted strong up-front regulatory scrutiny—but didn’t. The speed with which the FDA gave them the go-ahead—despite obvious red flags regarding their safety—illustrates the insincerity of the agency’s assertions that its vaccine approval process is committed to minimizing risks.
The FDA not only gave the quadrivalent Gardasil a free pass but has repeatedly reapproved it and the nine-valent Gardasil-9 for wider use. (Gardasil-9 is a newer formulation that contains more than twice the amount of neurotoxic aluminum adjuvant as Gardasil.) In 2009, the FDA also okayed GlaxoSmithKline’s HPV vaccine, Cervarix, but Merck’s FDA-facilitated stranglehold on the market prompted the company to withdraw Cervarix from the U.S. in 2016. Merck is now aggressively expanding its Gardasil “franchise” into other countries, generating unprecedentedworldwide demand, while continuing to “rev up” U.S. sales.
Since 2006, the FDA’s Gardasil-related decisions have included:
- 2006: Granting fast-tracked approval for the original quadrivalent Gardasil vaccine (girls and women aged 9 to 26 years)
- 2009: Approving Gardasil’s use in boys and men (ages 9-26)
- 2014: Approving Gardasil-9 (girls ages 9-26, boys ages 9-15)
- 2015: Approving Gardasil-9 for boys ages 16-26
- 2018: Approving Gardasil-9 for older women and men (ages 27-45)
An eight-month investigation by Slate identified numerous troubling aspects of the clinical trials that encouraged U.S. and European regulators to approve Gardasil. The Slate reporter also criticized regulators for allowing “unreliable methods to be used to test the vaccine’s safety.” These included Merck’s use of “a convoluted method” that made it difficult to objectively evaluate and report side effects; its failure to document “symptom severity, duration, outcome, or overall seriousness”; restriction of adverse event reporting to just 14 days following each injection; and reliance on the subjective opinion of clinical trial investigators regarding “whether or not to report any medical problem as an adverse event.” Not infrequently, clinical trial participants who shared complaints of debilitating symptoms with trial investigators were dismissed with the response, “This is not the kind of side effects we see with this vaccine.”
The author of the Slate investigation reported:
Experts I talked to were baffled by the way Merck handled safety data in its trials. According to…a professor…who studies side effects, letting investigators judge whether adverse events should be reported is “not a very safe method of doing things, because it allows bias to creep in.” …Of the short follow-up…,“It’s not going to pick up serious long-term issues, which is a pity. Presumably, the regulators believe that the vaccine is so safe that they don’t need to worry beyond 14 days.”
Two years after Gardasil’s initial approval, Judicial Watch pronounced it a “large-scale public health experiment.” Post-licensure studies carried out since then confirm that HPV vaccines have grave risks, including impaired fertility, demyelinating disease, chronic limb pain, circulatory abnormalities and autoimmune illness, to name just some of the disabilities reported in the aftermath of HPV vaccines’ introduction. Overall, the “rate of reported serious adverse reactions (including deaths) from HPV vaccination” is many times higher than the cervical cancer mortality rate.
Recent data suggest that HPV vaccines may be increasing cervical cancer risks.
In a February 2019 letter to the CDC, Children’s Health Defense Chairman Robert F. Kennedy, Jr. noted, “During Gardasil’s clinical trials, an extraordinary 49.5% of the subjects receiving Gardasil reported serious medical conditions within seven months of the start of the clinical trials. Because Merck did not use a true placebo in its clinical trials, its researchers were able to dismiss these injuries as sad coincidences.” A current civil case brought on behalf of a 24-year-old who has suffered from systemic autoimmune dysregulation since receiving her third Gardasil vaccine at age 16 alleges that Merck “committed fraud during its clinical trials and then failed to warn [vaccine recipients] about the high risks and meager benefits of the vaccine.” The trial’s legal team is benefiting from the support of an “A-team” of plaintiffs’ law firms and attorneys, including Kennedy, Jr.
Recent data suggest that HPV vaccines may be increasing cervical cancer risks. A 2017 study out of Australia—which has heavily promoted routine HPV vaccination since 2007—reported an increased risk of difficult-to-detect malignant cervical lesions among the HPV-vaccinated. In all countries where HPV vaccination coverage is high, including Australia, official cancer registries show “an increase in the incidence of invasive cervical cancer” in the vaccinated age groups. In England, “2016 national statistics showed a worrying and substantial increase in the rate of cervical cancer…at ages 20-24”—the first HPV-vaccinated cohort.
The proper decision would be to take HPV vaccines off the market, but the FDA and CDC continue to look the other way. Both agencies’ unwavering support for Gardasil has clearly helped Merck’s commercial bottom line, so much so that the CDC director at the time of Gardasil’s approval (Julie Gerberding) went on to be appointed president of Merck’s profitable vaccine division (worth $5 billion globally) in 2009. The agencies’ willingness to aggressively promote HPV vaccination despite its readily apparent dangers illustrates a “public health flimflam” of the first order. Before the U.S. introduction of HPV vaccination, a decades-long pattern of declining cervical cancer rates was already well underway, thanks to routine cervical cancer screening. HPV vaccines have never even been proven to prevent cervical cancer. In 2016, researchers admitted that they would be unable to ascertain HPV vaccines’ long-term efficacy for “at least another 15-20 years.”
Officials also seem to have little interest in modern evidence documenting many vaccines’ inability to provide the promised protection, even when vaccine coverage is widespread.
Alongside their many misplaced claims about various vaccines’ rationale and safety record, the FDA and CDC—as echo chambers for the vaccine industry—also have misinformed the public about vaccine effectiveness. Back in 1899, doctor William Bailey (vaccination enthusiast and member of the State Board of Health in Louisville, Kentucky) was more honest, cautioning that “nothing is gained by claiming too much” about vaccine-induced immunity and stating that “the degree of immunity may vary with time and circumstance”—presaging the troublesome modern phenomena of vaccine failure and waning immunity. In the present day, officials are only too willing to “claim too much,” conveniently ignoring historical evidence that reductions in infectious disease had little to do with vaccines and far more to do with improvements in sanitation and nutrition. Officials also seem to have little interest in modern evidence documenting many vaccines’ inability to provide the promised protection, even when vaccine coverage is widespread.
The acellular version of pertussis (whooping cough)—a component of U.S. vaccines such as DTaP and Tdap—is one of the vaccines noted for its abysmal effectiveness. The vaccine is supposed to protect against the respiratory infection caused by Bordetella pertussis. Instead, according to recent studies, pertussis is making a “surprising” comeback; between 1990 and 2005, pertussis epidemics increased in the U.S. “in both size and frequency,” and over half of all cases occurred in highly vaccinated adolescents aged 10 to 20 years old. In fact, not only is pertussis at its highest level since the mid-1950s, but, according to CDC researchers, it is showing signs of being vaccine-resistant. The CDC researchers also note “substantial heterogeneity among vaccine recipients in terms of the durability of the protection they receive.”
… the researchers concluded in 2017 that all currently available evidence suggests that DTP vaccine may kill more children from other causes than it saves from diphtheria, tetanus or pertussis …
West Africa has used the DTP vaccine since the 1980s—formulated with a whole-cell pertussis component instead of acellular pertussis—and it has an even more horrifying safety and effectiveness record than its acellular counterparts. Research published in 2017 by a prestigious team of international scientists and led by vaccinology expert Dr. Peter Aaby found that DTP vaccination had a negative effect on child survival, with fivefold higher mortality in young DTP-vaccinated infants (ages three to five months) compared to as-yet-unvaccinated infants. When the researchers published results in 2018 for slightly older DTP-vaccinated children (ages six months to three years), they continued to observe more than double the risk of death as similarly situated unvaccinated children. Explaining that vaccines can increase susceptibility to other infections, the researchers concluded in 2017 that “all currently available evidence suggests that DTP vaccine may kill more children from other causes than it saves from diphtheria, tetanus or pertussis” and added in 2018 that “all studies of the introduction of DTP have found increased overall mortality.”
Learning from history
Efforts to counter the official vaccine narrative with evidence about negative consequences date back to the days of smallpox. A doctor practicing in the 1870s observed that smallpox mortality doubled (from roughly 7% to 15%) after adoption of smallpox vaccination. During an outbreak in 1871 and 1872, this doctor stated, faith in vaccination received a “rude…shock” when “[e]very country in Europe was invaded with a severity greater than had ever been witnessed during the three preceding centuries.” The doctor also noted that “many vaccinated persons in almost every place were attacked by small-pox before any unvaccinated persons took the disease.” In this individual’s estimation, these facts were “sufficient to overthrow the entire theory of the protective efficacy of vaccination.”
In the present era, federal agencies continue to tout difficult-to-justify but money-spinning vaccines as beneficial, even in the face of substantial evidence to the contrary. Now, more than ever, it is important to illuminate the risks and downsides that public health agencies do not want us to know about.
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