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Study “Confirms That The Full Degree of Harm of Antidepressants Is Not Reported”

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In Brief

  • The Facts:

    Multiple studies outlined in this article indicate a serious issue with the efficacy of anti-depressant drugs, and the lengths that pharmaceutical companies go to hide potential dangers.

  • Reflect On:

    How much science is there really behind the efficacy of anti-depressant drugs?

A study published in the British Medical Journal  by researchers at the Nordic Cochrane Center in Copenhagen showed that pharmaceutical companies were not disclosing all information regarding the results of their drug trials. Researchers looked at documents from 70 different double-blind, placebo-controlled trials of selective serotonin reuptake inhibitors (SSRI) and serotonin and norepinephrine reuptake inhibitors (SNRI) and found that the full extent of serious harm in clinical study reports went unreported. These are the reports sent to major health authorities like the U.S. Food and Drug Administration.

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Tarang Sharma, a PhD student at Cochrane and lead author of the study, said:

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We found that a lot of the appendices were often only available upon request to the authorities, and the authorities had never requested them. I’m actually kind of scared about how bad the actual situation would be if we had the complete data. (source)

Due to problems with selective reporting, even within CSRs, raw data from clinical drug trials should be preferred when conducting systematic reviews, with CSRs being the next-best option. As SSRIs and SNRIs can have very serious detrimental effects on children and adolescents, far more than previously noted, their use in young people should be reconsidered. In fact, even when considering all ages, placebo seems to be a better pill than an antidepressant drug because the patients weigh the benefits against the harms when they decide whether to stay in a trial or to drop out. (source)

Joanna Moncrieff, a psychiatrist and researcher at University College London, elaborates:

This study confirms that the full degree of harm of antidepressants is not reported. They are not reported in the published literature, we know that – and it appears that they are not properly reported in clinical study reports that go to the regulators and from the basis of decisions about licensing. (source)

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Peter Gotzsche, a clinician researcher at Cochrane and the co-author of the study, actually tried to gain access to clinical trial reports almost a decade ago for anti-obesity pills. Unfortunately, the European Medicines Agency (EMA) denied them the reports:

They talked about commercial confidentiality although there was absolutely nothing in these reports that was commercially confidential. We explained that all this secrecy actually cost human lives, but they weren’t interested in that at all. (source)

It took years of requests and complaints for this to happen and, while Gotzsche is pleased they were able to achieve this breakthrough, he reminds us that similar progress has yet to made in the United States. He went on to state that researchers need better access to data from clinical trials to conduct assessments unimpeded by industry influence:

It’s deeply unethical when patients volunteer to benefit science and then we let drug companies decide that we cannot get access to the raw data. The testing of drugs should be a public enterprise. (source)

Moncrieff (quoted above) then goes on to express further concerns:

We really don’t have good enough evidence that antidepressants are effective and we have increasing evidence that they can be harmful. So we need to go into reverse and stop this increasing trend of prescribing [them]. (source)

One of the latest studies published on the subjects titled “Should antidepressants be used for major depressive disorder” published in the British Medical Journal states,

The benefits of antidepressants seem to be minimal and possibly without any importance to the average patient with major depressive disorder. Antidepressants should not be used for adults with major depressive disorder before valid evidence has shown that the potential beneficial effects outweigh the harmful effects.

Related Study: Suicidality and aggression during antidepressant treatment:systematic review and meta-analyses based on clinical study reports

Many Antidepressant Studies Found Tainted by Pharma Company Influence

A study published in the Journal of Clinical Epidemiology revealed that a third of meta-analyses of antidepressant studies were written by pharma employees and that these were 22 times less likely than other meta-studies to include negative statements about the drug. That same month another research group reported that after reanalyzing the data from Study 329, a 2001 clinical trial of Paxil funded by GlaxoSmithKline, they uncovered exaggerated efficacy and undisclosed harm to adolescents.

Almost 80 percent of meta-analyses in the review had some sort of industry tie, either through sponsorship, which the authors defined as direct industry funding of the study, or conflicts of interest, defined as any situation in which one or more authors were either industry employees or independent researchers receiving any type of industry support (including speaking fees and research grants). Especially troubling, the study showed about 7 percent of researchers had undisclosed conflicts of interest. “There’s a certain pecking order of papers,” says Erick Turner, a professor of psychiatry at Oregon Health & Science University who was not associated with the research. “Meta-analyses are at the top of the evidence pyramid.” Turner was “very concerned” by the results but did not find them surprising. “Industry influence is just massive. What’s really new is the level of attention people are now paying to it.” (source)

Related CE Article: Depression: It’s Not Your Serotonin

The Takeaway

This corporate domination is exactly why, in 2014, the current Editor-in-Chief of The Lancet stated that “the case against science is straightforward: much of the scientific literature, perhaps half, may simply be untrue.” (source) It’s why Arnold Symour Relman emphasized that the “medical profession is being bought by the pharmaceutical industry, not only in terms of the practice of medicine, but also in terms of teaching and research.” He thought it was  “disgraceful” that the academic institutions of this country are allowing themselves to be the paid agents of the pharmaceutical industry.” (source)

This isn’t a secret, but it’s quite odd how substances like opioids get approved by our federal health regulatory agencies, which have clearly been compromised as well.

 

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Bill Gates’ Global Agenda & How We Can Resist His War On Life

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In March 2015, Bill Gates showed an image of the coronavirus during a TED Talk and told the audience that it was what the greatest catastrophe of our time would look like. The real threat to life, he said, is ‘not missiles, but microbes.’ When the coronavirus pandemic swept over the earth like a tsunami five years later, he revived the war language, describing the pandemic as ‘a world war’.

‘The coronavirus pandemic pits all of humanity against the virus,’ he said.

In fact, the pandemic is not a war. The pandemic is a consequence of war. A war against life. The mechanical mind connected to the money machine of extraction has created the illusion of humans as separate from nature, and nature as dead, inert raw material to be exploited. But, in fact, we are part of the biome. And we are part of the virome. The biome and the virome are us. When we wage war on the biodiversity of our forests, our farms, and in our guts, we wage war on ourselves.

The health emergency of the coronavirus is inseparable from the health emergency of extinction, the health emergency of biodiversity loss, and the health emergency of the climate crisis. All of these emergencies are rooted in a mechanistic, militaristic, anthropocentric worldview that considers humans separate from–and superior to–other beings. Beings we can own, manipulate, and control. All of these emergencies are rooted in an economic model based on the illusion of limitless growth and limitless greed, which violate planetary boundaries, and destroy the integrity of ecosystems and individual species.

New diseases arise because a globalized, industrialized, inefficient agriculture invades habitats, destroys ecosystems, and manipulates animals, plants, and other organisms with no respect for their integrity or their health. We are linked worldwide through the spread of diseases like the coronavirus because we have invaded the homes of other species, manipulated plants and animals for commercial profits and greed, and cultivated monocultures. As we clear-cut forests, as we turn farms into industrial monocultures that produce toxic, nutritionally empty commodities, as our diets become degraded through industrial processing with synthetic chemicals and genetic engineering, and as we perpetuate the illusion that earth and life are raw materials to be exploited for profits, we are indeed connecting. But instead of connecting on a continuum of health by protecting biodiversity, integrity, and self-organization of all living beings, including humans, we are connected through disease.

According to the International Labour Organization, ‘1.6 billion informal economy workers (representing the most vulnerable in the labour market), out of a worldwide total of two billion and a global workforce of 3.3 billion, have suffered massive damage to their capacity to earn a living. This is due to lockdown measures and/or because they work in the hardest-hit sectors.’ According to the World Food Programme, a quarter of a billion additional people will be pushed to hunger and 300,000 could die every day. These, too, are pandemics that are killing people. Killing cannot be a prescription for saving lives.

Health is about life and living systems. There is no ‘life’ in the paradigm of health that Bill Gates and his ilk are promoting and imposing on the entire world. Gates has created global alliances to impose top-down analysis and prescriptions for health problems. He gives money to define the problems, and then he uses his influence and money to impose the solutions. And in the process, he gets richer. His ‘funding’ results in an erasure of democracy and biodiversity, of nature and culture. His ‘philanthropy’ is not just philanthrocapitalism. It is philanthroimperialism.

The coronavirus pandemic and lockdown have revealed even more clearly how we are being reduced to objects to be controlled, with our bodies and minds as the new colonies to be invaded. Empires create colonies, colonies enclose the commons of the indigenous living communities and turn them into sources of raw material to be extracted for profits. This linear, extractive logic is unable to see the intimate relations that sustain life in the natural world. It is blind to diversity, cycles of renewal, values of giving and sharing, and the power and potential of self-organising and mutuality. It is blind to the waste it creates and to the violence it unleashes. The extended coronavirus lockdown has been a lab experiment for a future without humanity.

On March 26, 2020, at a peak of the coronavirus pandemic and in the midst of the lockdown, Microsoft was granted a patent by the World Intellectual Property Organization (WIPO). Patent WO 060606 declares that ‘Human Body Activity associated with a task provided to a user may be used in a mining process of a cryptocurrency system….’

The ‘body activity’ that Microsoft wants to mine includes radiation emitted from the human body, brain activities, body fluid flow, blood flow, organ activity, body movement such as eye movement, facial movement, and muscle movement, as well as any other activities that can be sensed and represented by images, waves, signals, texts, numbers, degrees, or any other information or data.

The patent is an intellectual property claim over our bodies and minds. In colonialism, colonisers assign themselves the right to take the land and resources of indigenous people, extinguish their cultures and sovereignty, and in extreme cases exterminate them. Patent WO 060606 is a declaration by Microsoft that our bodies and minds are its new colonies. We are mines of ‘raw material’–the data extracted from our bodies. Rather than sovereign, spiritual, conscious, intelligent beings making decisions and choices with wisdom and ethical values about the impacts of our actions on the natural and social world of which we are a part, and to which we are inextricably related, we are ‘users.’ A ‘user’ is a consumer without choice in the digital empire.

But that’s not the totality of Gates’ vision. In fact, it is even more sinister–to colonise the minds, bodies, and spirits of our children before they even have the opportunity to understand what freedom and sovereignty look and feel like, beginning with the most vulnerable.

In May 2020, Governor Andrew Cuomo of New York announced a partnership with the Gates Foundation to ‘reinvent education.’ Cuomo called Gates a visionary and argued that the pandemic has created ‘a moment in history when we can actually incorporate and advance [Gates’] ideas…all these buildings, all these physical classrooms–why with all the technology you have?’

In fact, Gates has been trying to dismantle the public education system of the United States for two decades. For him students are mines for data. That is why the indicators he promotes are attendance, college enrollment, and scores on a math and reading test, because these can be easily quantified and mined. In reimagining education, children will be monitored through surveillance systems to check if they are attentive while they are forced to take classes remotely, alone at home. The dystopia is one where children never return to schools, do not have a chance to play, do not have friends. It is a world without society, without relationships, without love and friendship.

As I look to the future in a world of Gates and Tech Barons, I see a humanity that is further polarized into large numbers of ‘throw away’ people who have no place in the new Empire. Those who are included in the new Empire will be little more than digital slaves.

Or, we can resist. We can seed another future, deepen our democracies, reclaim our commons, regenerate the earth as living members of a One Earth Family, rich in our diversity and freedom, one in our unity and interconnectedness. It is a healthier future. It is one we must fight for. It is one we must claim.

We stand at a precipice of extinction. Will we allow our humanity as living, conscious, intelligent, autonomous beings to be extinguished by a greed machine that does not know limits and is unable to put a break on its colonisation and destruction? Or will we stop the machine and defend our humanity, freedom, and autonomy to protect life on earth?

Written By Dr. Vandana Shiva- The above is excerpted from Vandana Shiva’s book Oneness vs. the 1%: Shattering Illusions, Seeding Freedom (Chelsea Green Publishing, August 2020) and is reprinted with permission from the publisher.

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British Foreign Secretary Says “False Positive Rate” For COVID-19 Is “Very High”

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In Brief

  • The Facts:

    British Foreign Secretary Dominic Raab recently stated that "The false positive rate rate is very high, so only seven percent of tests will be successful in identifying those that actually have the the virus"

  • Reflect On:

    Why is there so much conflicting information out there? How can the general population be expected to arrive at any sort of truth when this is the case? This puts critical thinking at the utmost of importance in these times.

What Happened: British Foreign Secretary Dominic Raab recently made an appearance on Sky News, and when asked about testing inside of airports he stated that, “The challenge is the false positive rate is very high, so only seven percent of tests will be successful in identifying those that actually have the the virus. So the truth is, we can’t just rely on that…”

He went on to mention that we must rely on self-isolation at home, and have further testing there as well as an overall effort to ramp up testing, but my question is, are the tests used at home any more accurate? Does this mean the infection fatality rate is actually higher because not as many people are infected? Or does this mean, as multiple studies have pointed out, that the number of infected people greatly exceed our current numbers (thus greatly lowing the fatality rate) and that the tests simply aren’t capable or properly identifying these people?

A false positive test means that people who test positive for the virus may not actually have it.

This theme has been floating around quite a bit lately, radio show host Julia Hartley-Brewer was one of the latest to do so as you can see below.

In July, professor Carl Heneghan, director for the centre of evidence-based medicine at Oxford University and outspoken critic of the current UK response to the pandemic, wrote a piece titled: “How many Covid diagnoses are false positives?” He has argued that due to a bit of a fluke involving some slightly complicated statistics, the proportion of positive tests that are false in the UK could be as high as 50%.

Former scientific advisor at Pfizer, Dr Mike Yeadon argued the proportion of positive tests that are false is actually “around 90%”.

The Bulgarian Pathology Association has taken the stance that the testing used to identify the new coronavirus in patients is “scientifically meaningless.” He criticized the World Health Organization (WHO) and called them “a criminal medical organization” for creating fear and hysteria without, according to him, providing any verifiable scientific proof of a pandemic. This may seem confusing as it goes against information that’s been published. For example, the National Institutes of Health (NIH) claims that “Potent antibodies found in people recovered from COVID-19.” (source) So it’s understandable how many people would not agree with the stance of the association, and claim that it is indeed false, and that’s an understandable perception,

They cite an article published in “Off Guardian” that makes some very interesting points. I recommend you read the entire article here to get the full scope of their reasoning.

Are they right? According to a recent Huffington Post article, “Yes, but only in a statistical sense. Applied to the real-world, the conclusions don’t stand up and are wildly misleading.”

The article is titled, “N0, 90 % of Coronavirus Tests Are Not ‘False Positives’ And This Is Why: Experts explain why a theory doing the rounds about the number of people wrongly diagnosed with cOVID-19 is simply not true.” 

According to Dr. Matthew Oughton, an infectious diseases specialist at the McGill University Health Centre and the Jewish General Hospital in Montreal,”The rate of false positives with this particular test is quite low. In other words, if the test comes back saying positive, then believe it, it’s a real positive.”

These are just a few of many examples of conflicting information.

Why This Is Important: It’s not hard to see why there is so much conflicting information out there. Expert in the field are completely separated in their belief with regards to the false positive issue, and there is information on both sides of the coin that completely, 100 percent contradicts the other perspective. How is the general population, or those who are taking the time to look into this issue supposed to arrive at any conclusion? At this point it seems nearly impossible, and what we often see from mainstream media is simply sharing a perspective or pushing a viewpoint for political purposes rather than a general desire to get to any sort of concrete truth.

This discrepancy highlights why in today’s day and age it’s important to conduct your own research and be aware of multiple perspectives. We must share information that comes from ‘credible’ sources, or information that is backed up with reasoning, questioning, proof and evidence. What seems to be happening with covid I find is that many people are sharing a lot of unsubstantiated information which makes it harder for the ‘alternative’ thinking community to arrive at any kind of truth. There are multiple examples. It also delegitimizes the ‘truth’ movement in this time of deceit and misinformation, and it allows ‘fact-checkers’ as well as mainstream media to group all of us who are in pursuit of truth as “conspiracy theorists” and justify their campaign of censorship on information that opposes the mainstream narrative.

With covid, we’ve seen some of the world’s leading experts in the field experience censorship simply for sharing information, opinions and evidence that contradicts the World Health Organization. Michael Levitt, a Biophysicist and a professor of structural biology at Stanford University is one of countless scientists to who have criticized the WHO as well as Facebook for censoring different information and informed perspectives regarding the Coronavirus.

Another huge issue we are facing today is people not reading articles, simply reading headlines and drawing their own conclusions without examining the sources used in the article to see how legit it actually is. We’ve left our minds available to those who wish to mould them and shape our perception of major events for ulterior motives.

The Takeaway

The mainstream and traditional media seem to be failing to have important conversations that are controversial, while at the same time perhaps there isn’t enough rigour and critical thinking in alternative media communities. Given we are deeply feeling the need to make sense of our world, is it time we begin to look at developing the inner faculties necessary to move beyond ideology, limited thinking patterns and truly begin looking at what evidence around us says?

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Infection Fatality “Estimates” For Covid-19 Via CDC: .00003%, .0002%, .005% & .054%

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In Brief

  • The Facts:

    The CDC has released "scenarios" based on a set of numerical values for biological and epidemiological characteristics of COVID-19 illness, which is caused by the SARS-CoV-2 virus. The emphasize they are are not predictions of estimated impact.

  • Reflect On:

    Why is there so much conflicting information out there when it coms to COVID-19? Does the politicization of science play a role?

What Happened: The CDC has a page on their website titled “Covid-19 Pandemic Planning Scenarios.” According to them, “Each scenario is based on a set of numerical values for biological and epidemiological characteristics of COVID-19 illness, which is caused by the SARS-CoV-2 virus. These values—called parameter values—can be used in models to estimate the possible effects of COVID-19 in U.S. states and localities. This document was first posted on May 20, 2020, with the understanding that the parameter values in each scenario would be updated and augmented over time, as we learn more about the epidemiology of COVID-19.  The September 10 update is based on data received by CDC through August 8, 2020.”

The Pandemic Planning Scenarios according to the CDC, are “designed to help inform decisions by public health officials who use mathematical modeling, and by mathematical modelers throughout the federal government.  Models developed using the data provided in the planning scenario tables can help evaluate the potential effects of different community mitigation strategies (e.g., social distancing).  The planning scenarios may also be useful to hospital administrators in assessing resource needs…”

In their latest update, age-specific estimates of Infection Fatality Ratios have been updated, one parameter measuring healthcare usage has been replaced with the median number of days from symptom onset to positive SARS-CoV-2 test, and a new parameter has been included: Ratio of Estimated Infections to Reported Case Counts, which is based on recent serological data from a commercial laboratory survey in the U.S.

 

Scenarios 1 through 4 are based on parameter values that represent the lower and upper bounds of disease severity and viral transmissibility (moderate to very high severity and transmissibility). The parameter values used in these scenarios are likely to change as we obtain additional data about the upper and lower bounds of disease severity and the transmissibility of SARS-CoV-2, the virus that causes COVID-19. Scenario 5 represents a current best estimate about viral transmission and disease severity in the United States, with the same caveat: the parameter values will change as more data become available.

The CDC emphasizes the following:

The scenarios are intended to advance public health preparedness and planning.  They are not predictions or estimates of the expected impact of COVID-19.  The parameter values in each scenario will be updated and augmented over time, as we learn more about the epidemiology of COVID-19.  Additional parameter values might be added in the future (e.g., population density, household transmission, and/or race and ethnicity).

For complete information regarding COVID-19 planning scenarios from the CDC, you can click here.

More Info on COVID-19 Infection/Fatality: According to the World Health Organization (WHO), “An important characteristic of an infectious disease, particularly one caused by a novel pathogen like SARS-CoV-2, is its severity, the ultimate measure of which is its ability to cause death. Fatality rates help us understand the severity of a disease, identify at-risk populations, and evaluate quality of healthcare.”

In early August, they provided a scientific brief explaining how it’s calculated, and how difficult it is to calculate and list all of the variables involved. You can read that here.

The Physicians For Informed Consent (PIC) recently published a report titled “Physicians for Informed Consent (PIC) Compares COVID-19 to Previous Seasonal and Pandemic Flu Periods.” In their article, they stated the following:

The public has been made aware of the number of COVID-19 deaths and reported cases that have occurred since the beginning of the current pandemic; however, the number of unreported cases has not been widely known or publicized. Recently, the Centers for Disease Control and Prevention (CDC) estimated that more than one-third of SARS-CoV-2 (the coronavirus that can lead to COVID-19) infections are asymptomatic, meaning that initial estimations of its severity were grossly overestimated. Now, for the first time, Physicians for Informed Consent (PIC) has collated data from U.S. antibody studies and produced an educational document outlining how an accurate case-fatality rate (CFR) requires antibody studies in order to guide and measure medical care and public health policies.

Similar to CDC estimations, PIC’s analysis results in a COVID-19 CFR of 0.26%, which is comparable to the CFRs of previous seasonal and pandemic flu periods. “Knowing the CFR of COVID-19 allows for an objective standard by which to compare both non-pharmaceutical interventions and medical countermeasures,” said Dr. Shira Miller, PIC’s founder and president. “For example, safety studies of any potential COVID-19 vaccine should be able to prove whether or not the risks of the vaccine are less than the risks of the infection.

“Regardless of proof of safety, however, a potential COVID-19 vaccine should only be voluntary, in order to safeguard a patient’s human right to determine what will happen with his or her body,” said Dr. Miller.

You can view the PIC’s educational document assessing COVID-19 severity and how they came to their conclusion, here. Obviously the data is always delayed and things are constantly changing with regards to COVID-19 numbers.

Another variable is the fact that deaths being attributed to COVID-19 may not even be a result of COVID-19. You can read more about that and see some examples here.

John P. A. Ioannidis, a professor of medicine and epidemiology at Stanford University has said that the infection fatality rate is close to 0 percent for people under the age of 45 years old, explaining how that number rises significantly for people who are older, as with most other respiratory viruses. You can read more about that and access that here.

Michael Levitt, a Biophysicist and a professor of structural biology at Stanford University, is one of many who have criticized the WHO as well as Facebook for censoring different information and informed perspectives regarding the Coronavirus. He has shared his experience thus far:

Almost all of the science we were hearing, for example like organizations like the World Health Organization (WHO) was wrong…This has been a disgraceful situation for science..Reports were released openly, shared by email, and all I got back was abuse. And you got to see that everything I said in that first six weeks was actually true and for political reasons, we as scientists let our views be corrupted. The data had very clear things to say. Nobody said to be “let me check your numbers” they all just said “stop talking like that.”

More than 500 German doctors & scientists have signed on as representatives of an organization called the “Corona Extra-Parliamentary Inquiry Committee” to investigate what’s happening on our planet with regards to COVID-19. They are also confused at what’s going on. You can read more about that here.

A common theme during this pandemic has been many of the world’s leading scientists in the field criticizing the measures taken by governments for something that may not be as severe as it’s been made out to be.

An article published in the British Medical Journal  has suggested that quarantine measures in the United Kingdom as a result of the new coronavirus may have already killed more UK seniors than the coronavirus has during the peak of the virus. You can access that and read more about it here

Dr. Sucharit Bhakdi, a specialist in microbiology and one of the most cited research scientists in German history is also part of Corona Extra-Parliamentary Inquiry Committee mentioned above and has also expressed the same thing, multiple times early on in the pandemic all the way up to today.

Implementation of the current draconian measures that are so extremely restrict fundamental rights can only be justified if there is reason to fear that a truly, exceptionally dangerous virus is threatening us. Do any scientifically sound data exist to support this contention for COVID-19? I assert that the answer is simply, no. – Bhakdi. You can read more about him here.

The Takeaway: We have to ask ourselves, why are so many experts in the field being completely censored. Why is there so much information being shared that completely contradicts the narrative of our federal health regulatory agencies and organizations like the WHO? Why are we being made to believe that there is no solution for this except for a vaccine? Why is it so hard to find out what’s going on these days, and why is there so much conflicting information out there? Does the politicization of science play a role?

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